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ACE2", "polymorphism", "DPP4" and "telemedicine" was conducted on Pubmed and EMBASE till 7th August 2020. RESULT: Possible polymorphisms in ACE2 gene can play a role in influencing the virus entry in host body. Telemedicine can bring a new revolution for medical sector. CONCLUSION: COVID-19 severity is more heinous among diabetic population. So far, the in-silico studies involving human ACE2-viral Spike (S) interaction showed inconsistent predictions regarding some SNPs. But without actual in-vivo studies, a holistic understanding can't be established.">COVID-19 and diabetes; Possible role of polymorphism and rise of telemedicine. Sayed S, et. al. (2021); Prim Care Diabetes; 2021 02 ; 15 (1) 4-9. doi:10.1016/j.pcd.2020.08.018
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MESH:C000657245 covid-19|SARS-CoV-2 infection|SARS-CoV infection|COVID-19MESH:C565965 TSI IBS CEU GBR FIN EAS SAS AFR AMR SRB|TSI IBS FIN GBR CEU EAS SAS AFR AMR PLGMESH:D000077277 esophageal squamous cell carcinomaMESH:D001102 viral diseases|viral infection|viral infectionsMESH:D003141 infectious diseasesMESH:D003550 cystic fibrosisMESH:D003643 mortality|deathMESH:D003922 type I diabetesMESH:D007239 infections|infection|infectedMESH:D009103 multiple sclerosisMESH:D010195 pancreatitisMESH:D011014 pneumoniaMESH:D012120 acute respiratory syndrome|acute respiratory syndrome coronavirus infectionMESH:D012140 respiratory diseaseMESH:D012598 sclerosisMESH:D015658 HIV infection|HIV-1 infection|human diseases or disordersMESH:D016098 GSDMESH:D018352 respiratory syndrome coronavirus infectionMESH:D030342 Mendelian diseasesMESH:D045169 severe acute respiratory syndromeMESH:D055744 invasive aspergillosis
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MESH:C000657245 SARS-CoV infection|SARS-CoV and SARS-CoV-mt|SARS-CoV-mt-infected|CoV infection|SARS-CoV and SARS-CoV|CoV genera|SARS-CoV infectivity|SARS-CoV N antibody|chemokines Bat CoV|alpha-CoV, beta-CoV, gamma-CoV and delta-CoV|alpha-CoV and beta-CoV|SARS-CoV and MERS-CoV|SARS-CoV-infected|SARS-CoV and SARS-CoV-mt-infected|SARS-CoV-mt|SARS-CoV|CoV belonging|CoV|SARS-CoV- and SARS-CoV-mt-infected|CoV and beta-CoVMESH:C536751 SCoV-WTMESH:C538265 attenuated CoVMESH:C564422 respiratory syndrome coronavirus ADP-ribose-1"-phosphate dephosphorylationMESH:D001991 infectious bronchitisMESH:D003333 HCoV-229E, HCoV-HKU1MESH:D003924 HKU9-1, HKU9-2MESH:D004751 enteric diseasesMESH:D007239 mock-infected|infectionMESH:D007674 embryonic kidneyMESH:D011014 pneumoniaMESH:D012128 respiratory distress syndromeMESH:D012131 respiratory infection|viral respiratory disease|respiratory syndrome|respiratory syndrome CoV|respiratory diseaseMESH:D012497 beta-CoVMESH:D015430 SARS-CoV nsp1 gains accessMESH:D015658 virus infectionMESH:D016537 HKU9-1, belonging to beta-CoVBMESH:D018352 Coronavirus|respiratory syndrome coronavirus infection|coronavirus respiratory infections|SARS-coronavirus causes disease|respiratory syndrome CoV and Middle East respiratory syndrome CoV|Middle East respiratory syndrome CoV|coronavirus MHV-A59|Coronavirus Nonstructural|respiratory syndrome coronavirus Nsp15|coronavirus infections|respiratory syndrome coronavirus 3a|SARS Coronavirus|respiratory syndrome coronavirus|coronavirus|SARS-coronavirus-host|MERS|rhinovirus and coronavirusMESH:D018455 SARS-CoV SMESH:D042822 CoV genome|SARS-CoV genomeMESH:D045169 Coronaviruses post-SARS
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The Rho ADP-ribosylating C3 exoenzyme binds cells via an Arg-Gly-Asp motif. Rohrbeck A, et. al. (2017); J. Biol. Chem.; 2017 10 27; 292(43) 17668-17680. doi:10.1074/jbc.M117.798231
The Nigral Coup in Parkinson's Disease by alpha-Synuclein and Its Associated Rebels. Sian-Hulsmann J, et. al. (2021); Cells; 2021 Mar 09 ; 10 (3) . doi:10.3390/cells10030598
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2 infected|CoV-2 infected|SARS-CoV-2-infected|COVID 19|Covid-19|COVID-19|COVIDMESH:C535733 der Substantia nigra pars compacta beim idiopathischen Parkinson-Syndrom.StructureMESH:C537475 Mitochondrial complex I deficiencyMESH:C562385 iron dyshomeostasisMESH:C566823 autosomal-dominant parkinsonismMESH:D000068079 motor dysfunction|motor abnormalitiesMESH:D000079225 StressMESH:D000080874 alpha-synucleinopathy|neurodegenerative synucleinopathiesMESH:D000370 hypogeusiaMESH:D000544 Alzheimer's disease|Alzheimer's disease brainsMESH:D000857 Hyposmia|hyposmiaMESH:D000860 hypoxiaMESH:D001102 viral infection|immunodeficiency virus-infected|immunodeficiency virus infection|viral infectionsMESH:D001284 atrophyMESH:D001480 extrapyramidal movement disordersMESH:D001927 encephalopathy|EncephalopathyMESH:D002534 hypoxic brain injuryMESH:D003141 LB diseaseMESH:D003643 Death|neurodegenerative cell deathMESH:D003693 deliriumMESH:D003704 dementiaMESH:D003711 demyelinating diseaseMESH:D003920 diabetesMESH:D004409 akinesiaMESH:D004660 encephalitisMESH:D004672 encephalitis BMESH:D005911 gliosisMESH:D006333 autonomic failureMESH:D006432 iron storage diseaseMESH:D006623 Verteilung von NoradrenalinMESH:D007153 deficiency|immunodeficiency virus/HIVMESH:D007239 Infections|Infection|infected|infectionMESH:D007249 inflammation|acute inflammationMESH:D008569 memory TMESH:D008659 metabolic diseasesMESH:D009069 Movement disordersMESH:D009127 Hypokinetic-rigid movement disordersMESH:D009336 Tumor necrosisMESH:D009410 neuronal loss|SN neuronal loss|neuronal dysfunction|neuronal necrosis|neuronal cell death|SN neuronal degeneration|neuronal damageMESH:D009421 neurological defectsMESH:D009422 neurological symptomsMESH:D009443 Lewy neuritisMESH:D009461 motor deficits|dysfunctionalMESH:D010300 Parkinson's Disease|idiopathic Parkinson's disease|PD brains|Parkinson's|PD|parkinsonsim and Parkinson's disease|Parkinson's disease|familial Parkinson's disease|Parkinson disease|PD-like injury|Lewy bodies of Parkinson disease|Parkinson Disease|neurodegenerative disorder Parkinson's disease|Idiopathic Parkinson's disease|Parkinson's disease-a multifactorial neurodegenerative disorder|autosomal dominant PDMESH:D010301 encephalitis lethargica|encephalitic parkinsonism|postencephalitic parkinsonism|Encephalitis lethargicaMESH:D010302 Parkinson|parkinsonismMESH:D010859 pigmentationMESH:D012120 respiratory syndromeMESH:D012128 acute respiratory distress syndrome|ARDSMESH:D012162 degeneration via microgliosisMESH:D012791 systems atrophies|degeneration in multiple systems atrophyMESH:D013167 SpondyloarthritisMESH:D013226 status epilepticusMESH:D013651 mitochondriopathy, dysfunction of metal homeostasisMESH:D014202 tremorMESH:D015526 HIV dementia|Parkinsonism in HIV dementia|AIDS Dementia ComplexMESH:D015658 HIV-infected|HIV infectionMESH:D016464 lysosomal disordersMESH:D018352 coronavirus diseaseMESH:D018476 bradykinesiaMESH:D019636 neurodegenerative disorders|neurodegenerative maladies|Neurodegeneration|neurodegenerative diseases|neurodegeneration|SN neurodegeneration|neurodegenerative disorderMESH:D020031 Epstein-BarrMESH:D020258 neurotoxic|neurotoxicityMESH:D020271 Neurological DiseasesMESH:D020521 strokesMESH:D020734 parkinsonian deficits|autosomal recessive parkinsonism|parkinsonian brains|Parkinson-like syndrome|parkinsonian|parkinsonian brainMESH:D020961 Lewy body disease|Lewy body diseasesMESH:D028361 mitochondrial deficits|mitochondrial dysfunction|Mitochondrial dysfunctionMESH:D030342 genetic defect|genetic abnormality|neuropathogenesis of the disorderMESH:D034721 system dysfunctionMESH:D057165 proteostasisMESH:D064420 cytotoxicity|toxicityMESH:D065703 Neuronal ApoptosisOMIM:256040 proteasomal dysfunction
Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases. Li L, et. al. (2020); Brain Behav Immun; 2020 Oct 08 . doi:10.1016/j.bbi.2020.10.007
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2-infected|coronavirus disease-2019|COVID-19|COVID19 InfectMESH:C535882 JohnsonMESH:C536050 OGDMESH:C536395 HSV encephalitis|HSV-1 infection|HSV-2 infectionMESH:C538265 IC Attenuates Reactive AstrogliosisMESH:C566985 brain atrophyMESH:D000067390 ColdMESH:D000070642 Traumatic Brain Injury|traumatic brain Injury|traumatic brain injuryMESH:D000080874 synucleinopathies|synucleinopathyMESH:D000163 AIDS brains|acquired immunodeficiency syndrome|AIDSMESH:D000370 hypogeusia/hyposmia|ageusiaMESH:D000544 Alzheimer|Alzheimer's disease|Alzheimer disease brains|Alzheimer's Disease|AD|Alzheimer diseaseMESH:D000690 amyotrophic lateral sclerosis|Amyotrophic lateral sclerosisMESH:D000783 spinal cord ischemiaMESH:D000857 anosmiaMESH:D001102 Neurotropic virus infections|Virus Infections|virus-infected|Viral diseases|viral infections|Infectious Diseases Viral infection|Viral infections|Virus Infection|virus infection|viral infectionMESH:D001327 autoimmunityMESH:D001424 bacterial infections|astroglial TLRs in bacterial infections|bacterial infectionMESH:D001480 axonal damageMESH:D001523 behavioral deficits|neuro-psychiatric disordersMESH:D001925 brain damage|Brain DamageMESH:D001927 encephalopathyMESH:D001930 ischemic brain injuryMESH:D002006 Brucella infections|Brucella abortus infection|Brucella infection|brucellosis increasesMESH:D002493 astroglial TLRs in CNS disease|CNS dysfunction|CNS injury and disease|Traumatic CNS injury|CNS injury|CNS disorders|traumatic CNS injuries|astroglial TLRs to CNS injuries|CNS disease and injuryMESH:D002494 central nervous system infection|astroglial TLRs in CNS infections|CNS infections|CNS infections via involvement of TLRs|Infections of the Central Nervous System|CNS infection|central nervous system infectionsMESH:D002534 hypoxic injury|hypoxic damageMESH:D002544 ischemic focal stroke|artery ischaemic strokeMESH:D002545 Cerebral Ischemia|cerebral ischemia|brain ischemiaMESH:D002561 cerebrovascular diseaseMESH:D003072 memory loss and cognitive deficits|cognitive impairment|Cognitive impairment|HIV infection of the brain impairs cognitiveMESH:D003141 cardiorespiratory disease|infectious diseasesMESH:D003643 mortality|Death|death|Mortality and DiseaseMESH:D003711 demyelination|chronic demyelinating diseaseMESH:D004194 Damage and Lethal Disease|injuries and diseasesMESH:D004487 swelling|ischemia Astrocyte swelling/edema|edemaMESH:D004660 meningitis/encephalitis|Encephalitis|encephalitisMESH:D004673 acute disseminated encephalomyelitisMESH:D004679 encephalomyelitisMESH:D005911 white matter gliosis|gliosisMESH:D005935 Tumor Necrosis Factor-alphaMESH:D006313 Neurosensory dysfunctionMESH:D006333 heart failureMESH:D006816 HD|Huntington's disease|Huntington diseaseMESH:D006984 hypertrophyMESH:D007027 hypothalamicMESH:D007153 immunodeficiency virus|TLR4 deficiency|TLR3 Deficiency|TLR deficiency|TLR3 deficiencyMESH:D007154 immune system failureMESH:D007239 Infections|infection|Infection|Infected|life-long infection|infections|infected|neuronal infectionMESH:D007249 inflammation|RAGE-TLR Crosstalk Sustains Chronic Inflammation|inflammatory disease|InflammationMESH:D007511 ischemicMESH:D008107 ALS-like diseaseMESH:D008113 familial ALSMESH:D008581 meningitisMESH:D008831 microcephaly and congenital brain anomaliesMESH:D009103 multiple sclerosis|multiple sclerosis brainMESH:D009336 necroticMESH:D009369 cancer|TumorMESH:D009410 neuronal death|neuronal degeneration|neuronal loss|neuronal injury|neuronal damage|neuronal toxicity|axonal degenerationMESH:D009422 neurological symptoms|nervous system injury and disease|neurological dysfunction|neurological disorders|Non-Cell-Autonomous Neurodegeneration|Neurological DisordersMESH:D009437 neuropathic painMESH:D009461 degeneration and dysfunction|neurological deficitsMESH:D010146 painMESH:D010243 paralysisMESH:D010300 Parkinson's Disease|Neuropathology of Parkinson disease|PD|Abeta Neuronal death Parkinson's Disease|Parkinson's disease|Parkinson's disease brain|Parkinson's disease brainsMESH:D010301 encephaliticMESH:D011273 prolongs neuroinflammationMESH:D011537 itchMESH:D012131 respiratory failureMESH:D012598 sclerosis|SclerosisMESH:D012640 seizuresMESH:D012769 heat shock proteinsMESH:D012892 glucose deprivationMESH:D013118 spinal cord astrocytic swellingMESH:D013119 spinal cord injuries|spinal cord injuryMESH:D013120 glia of ALS spinal cordMESH:D014901 WNV infectionsMESH:D014947 injuriesMESH:D015047 zoonoticMESH:D015427 spinal cord ischemia-reperfusion injuryMESH:D015526 AIDS dementiaMESH:D015658 HIV-infected|HIV infection|HIV-1 infection|immunodeficiency virus type 1 infectionMESH:D016263 HIV-1-associated neuropathologyMESH:D016920 bacterial meningitisMESH:D017827 JosephMESH:D018177 flavivirus infections|flavivirus infectionMESH:D018352 coronavirus infections|MERS|coronavirus infection|Middle East Respiratory Syndrome|Middle East respiratory syndrome coronavirus infectionMESH:D018980 WilliamsMESH:D019636 Neurodegeneration|injury and neurodegenerative diseases|neurodegenerative diseases|neurodegeneration|Neurodegenerative diseases|neurodegenerative disorders|astroglial TLRs to neurodegenerative diseases|neurodegenerative disorder|neurodegenerative diseaseMESH:D019965 neurocognitive impairmentMESH:D020258 astrocyte neurotoxicity|Neurotoxic|neurotoxicMESH:D020271 neurological diseaseMESH:D020295 degeneration of ventral midbrainMESH:D020521 stroke|StrokeMESH:D045169 Severe Acute Respiratory Syndrome Coronavirus InfectionMESH:D056486 hepatitis coronavirusMESH:D056784 white matter lesionsMESH:D064420 toxicity
Diversity and versatility of p38 kinase signalling in health and disease. Canovas B, et. al. (2021); Nat Rev Mol Cell Biol; 2021 Jan 27 . doi:10.1038/s41580-020-00322-w
Human iPSC-Based Modeling of Central Nerve System Disorders for Drug Discovery. Qian L, et. al. (2021); Int J Mol Sci; 2021 Jan 26 ; 22 (3) . doi:10.3390/ijms22031203
The Nigral Coup in Parkinson's Disease by alpha-Synuclein and Its Associated Rebels. Sian-Hulsmann J, et. al. (2021); Cells; 2021 Mar 09 ; 10 (3) . doi:10.3390/cells10030598
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2 infected|CoV-2 infected|SARS-CoV-2-infected|COVID 19|Covid-19|COVID-19|COVIDMESH:C535733 der Substantia nigra pars compacta beim idiopathischen Parkinson-Syndrom.StructureMESH:C537475 Mitochondrial complex I deficiencyMESH:C562385 iron dyshomeostasisMESH:C566823 autosomal-dominant parkinsonismMESH:D000068079 motor dysfunction|motor abnormalitiesMESH:D000079225 StressMESH:D000080874 alpha-synucleinopathy|neurodegenerative synucleinopathiesMESH:D000370 hypogeusiaMESH:D000544 Alzheimer's disease|Alzheimer's disease brainsMESH:D000857 Hyposmia|hyposmiaMESH:D000860 hypoxiaMESH:D001102 viral infection|immunodeficiency virus-infected|immunodeficiency virus infection|viral infectionsMESH:D001284 atrophyMESH:D001480 extrapyramidal movement disordersMESH:D001927 encephalopathy|EncephalopathyMESH:D002534 hypoxic brain injuryMESH:D003141 LB diseaseMESH:D003643 Death|neurodegenerative cell deathMESH:D003693 deliriumMESH:D003704 dementiaMESH:D003711 demyelinating diseaseMESH:D003920 diabetesMESH:D004409 akinesiaMESH:D004660 encephalitisMESH:D004672 encephalitis BMESH:D005911 gliosisMESH:D006333 autonomic failureMESH:D006432 iron storage diseaseMESH:D006623 Verteilung von NoradrenalinMESH:D007153 deficiency|immunodeficiency virus/HIVMESH:D007239 Infections|Infection|infected|infectionMESH:D007249 inflammation|acute inflammationMESH:D008569 memory TMESH:D008659 metabolic diseasesMESH:D009069 Movement disordersMESH:D009127 Hypokinetic-rigid movement disordersMESH:D009336 Tumor necrosisMESH:D009410 neuronal loss|SN neuronal loss|neuronal dysfunction|neuronal necrosis|neuronal cell death|SN neuronal degeneration|neuronal damageMESH:D009421 neurological defectsMESH:D009422 neurological symptomsMESH:D009443 Lewy neuritisMESH:D009461 motor deficits|dysfunctionalMESH:D010300 Parkinson's Disease|idiopathic Parkinson's disease|PD brains|Parkinson's|PD|parkinsonsim and Parkinson's disease|Parkinson's disease|familial Parkinson's disease|Parkinson disease|PD-like injury|Lewy bodies of Parkinson disease|Parkinson Disease|neurodegenerative disorder Parkinson's disease|Idiopathic Parkinson's disease|Parkinson's disease-a multifactorial neurodegenerative disorder|autosomal dominant PDMESH:D010301 encephalitis lethargica|encephalitic parkinsonism|postencephalitic parkinsonism|Encephalitis lethargicaMESH:D010302 Parkinson|parkinsonismMESH:D010859 pigmentationMESH:D012120 respiratory syndromeMESH:D012128 acute respiratory distress syndrome|ARDSMESH:D012162 degeneration via microgliosisMESH:D012791 systems atrophies|degeneration in multiple systems atrophyMESH:D013167 SpondyloarthritisMESH:D013226 status epilepticusMESH:D013651 mitochondriopathy, dysfunction of metal homeostasisMESH:D014202 tremorMESH:D015526 HIV dementia|Parkinsonism in HIV dementia|AIDS Dementia ComplexMESH:D015658 HIV-infected|HIV infectionMESH:D016464 lysosomal disordersMESH:D018352 coronavirus diseaseMESH:D018476 bradykinesiaMESH:D019636 neurodegenerative disorders|neurodegenerative maladies|Neurodegeneration|neurodegenerative diseases|neurodegeneration|SN neurodegeneration|neurodegenerative disorderMESH:D020031 Epstein-BarrMESH:D020258 neurotoxic|neurotoxicityMESH:D020271 Neurological DiseasesMESH:D020521 strokesMESH:D020734 parkinsonian deficits|autosomal recessive parkinsonism|parkinsonian brains|Parkinson-like syndrome|parkinsonian|parkinsonian brainMESH:D020961 Lewy body disease|Lewy body diseasesMESH:D028361 mitochondrial deficits|mitochondrial dysfunction|Mitochondrial dysfunctionMESH:D030342 genetic defect|genetic abnormality|neuropathogenesis of the disorderMESH:D034721 system dysfunctionMESH:D057165 proteostasisMESH:D064420 cytotoxicity|toxicityMESH:D065703 Neuronal ApoptosisOMIM:256040 proteasomal dysfunction
360" days post-injection (dpi), pathological alphaSyn conversion or clinical symptoms in transgenic TgM83+/- mice hemizygously expressing mutated (A53T) human alphaSyn (Prusiner et al. 2015, PNAS 112:E5308-E5317). To advance the assessment of possible alphaSynPD hazards by providing further data, we examined neuropathological and clinical effects upon i.c. transmission of brain, stomach wall and muscle tissue as well as blood from PD patients in TgM83+/- mice up to 612 dpi. This revealed a subtle, yet distinctive stimulation of localized alphaSyn aggregation in the somatodendritic compartment and dystrophic neurites of individual or focally clustered cerebral neurons after challenge with brain and stomach wall homogenates. No such effect was observed with transmitted blood or homogenized muscle tissue. The detected stimulation of alphaSyn aggregation was not accompanied by apparent motor impairments or overt neurological disease in TgM83+/- mice. Our study substantiated that transmitted alphaSynPD seeds, including those from the stomach wall, are able to propagate in new mammalian hosts. The consequences of such propagation and potential safeguards need to be further investigated.">Transmissible alpha-synuclein seeding activity in brain and stomach of patients with Parkinson's disease. Thomzig A, et. al. (2021); Acta Neuropathol; 2021 Apr 24 . doi:10.1007/s00401-021-02312-4
MESH:C000598645 spheroid-like alphaSyn immunolabellingMESH:C000657245 SARS-CoV-2-infected|Covid-19MESH:C536778 SCDMESH:C537412 substantia nigra reticulataMESH:C564858 PK-resistant alphaSyn depositsMESH:D000068079 motor impairmentsMESH:D000079822 cerebral alphaSyn depositsMESH:D000080874 synucleinopathyMESH:D000544 Alzheimer's disease|Alzheimer's|Alzheimer's transfer|AD|Alzheimer diseaseMESH:D001259 ataxiaMESH:D001284 atrophyMESH:D001791 alphaSyn aggregation|hMW alphaSynPD aggregates|immunolabelling of alphaSynPD aggregates|cerebral alphaSyn aggregation|immunolabelling of hMW alphaSynPD aggregates|cerebral aggregation|subtle cerebral aggregation|alphaSynPD aggregates|aggregated alphaSynPDMESH:D001796 cerebral protein aggregationMESH:D001927 encephalopathiesMESH:D002543 intracerebralMESH:D002544 ischemic strokeMESH:D003643 died|deathMESH:D003704 dementiaMESH:D006402 cerebral protein aggregation disease|alphaSyn aggregation disease|alphaSyn aggregation diseases|protein aggregation diseasesMESH:D006623 Nachweis der Freiheit von einer KrankheitMESH:D006816 HDMESH:D007049 iatrogenic alphaSynPDMESH:D007239 infection|infectedMESH:D009069 movement impairment|movement disorderMESH:D009207 MJMESH:D009422 neurological impairments or disease|neurological impairments|neurological symptomsMESH:D010243 paralysisMESH:D010300 idiopathic Parkinson's disease|NBH Non-PD|PD brains|Parkinson disease|Parkinson s disease|PD|Parkinson's disease|neuropathological hallmark of Parkinson's diseaseMESH:D010302 Parkinson|parkinsonismMESH:D014202 tremorMESH:D015431 weight lossMESH:D016472 motor diseaseMESH:D016657 cerebral amyloid angiopathyMESH:D018376 apathy or abnormalitiesMESH:D019636 nigrostriatal neurodegeneration|neurodegenerative protein aggregation disorders|neurodegenerative diseases|neurodegenerative protein aggregation disease|neurodegeneration|neurodegenerative diseaseMESH:D020271 Neurological disease|neurological diseaseMESH:D020961 Lewy body diseasesMESH:D053632 LB-linked alphaSynPDMESH:D058225 dystrophic neurite|somatodendritic/dystrophic neurite|neuritic alphaSyn|dystrophic neuritesMESH:D060825 impairments
The Nigral Coup in Parkinson's Disease by alpha-Synuclein and Its Associated Rebels. Sian-Hulsmann J, et. al. (2021); Cells; 2021 Mar 09 ; 10 (3) . doi:10.3390/cells10030598
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2 infected|CoV-2 infected|SARS-CoV-2-infected|COVID 19|Covid-19|COVID-19|COVIDMESH:C535733 der Substantia nigra pars compacta beim idiopathischen Parkinson-Syndrom.StructureMESH:C537475 Mitochondrial complex I deficiencyMESH:C562385 iron dyshomeostasisMESH:C566823 autosomal-dominant parkinsonismMESH:D000068079 motor dysfunction|motor abnormalitiesMESH:D000079225 StressMESH:D000080874 alpha-synucleinopathy|neurodegenerative synucleinopathiesMESH:D000370 hypogeusiaMESH:D000544 Alzheimer's disease|Alzheimer's disease brainsMESH:D000857 Hyposmia|hyposmiaMESH:D000860 hypoxiaMESH:D001102 viral infection|immunodeficiency virus-infected|immunodeficiency virus infection|viral infectionsMESH:D001284 atrophyMESH:D001480 extrapyramidal movement disordersMESH:D001927 encephalopathy|EncephalopathyMESH:D002534 hypoxic brain injuryMESH:D003141 LB diseaseMESH:D003643 Death|neurodegenerative cell deathMESH:D003693 deliriumMESH:D003704 dementiaMESH:D003711 demyelinating diseaseMESH:D003920 diabetesMESH:D004409 akinesiaMESH:D004660 encephalitisMESH:D004672 encephalitis BMESH:D005911 gliosisMESH:D006333 autonomic failureMESH:D006432 iron storage diseaseMESH:D006623 Verteilung von NoradrenalinMESH:D007153 deficiency|immunodeficiency virus/HIVMESH:D007239 Infections|Infection|infected|infectionMESH:D007249 inflammation|acute inflammationMESH:D008569 memory TMESH:D008659 metabolic diseasesMESH:D009069 Movement disordersMESH:D009127 Hypokinetic-rigid movement disordersMESH:D009336 Tumor necrosisMESH:D009410 neuronal loss|SN neuronal loss|neuronal dysfunction|neuronal necrosis|neuronal cell death|SN neuronal degeneration|neuronal damageMESH:D009421 neurological defectsMESH:D009422 neurological symptomsMESH:D009443 Lewy neuritisMESH:D009461 motor deficits|dysfunctionalMESH:D010300 Parkinson's Disease|idiopathic Parkinson's disease|PD brains|Parkinson's|PD|parkinsonsim and Parkinson's disease|Parkinson's disease|familial Parkinson's disease|Parkinson disease|PD-like injury|Lewy bodies of Parkinson disease|Parkinson Disease|neurodegenerative disorder Parkinson's disease|Idiopathic Parkinson's disease|Parkinson's disease-a multifactorial neurodegenerative disorder|autosomal dominant PDMESH:D010301 encephalitis lethargica|encephalitic parkinsonism|postencephalitic parkinsonism|Encephalitis lethargicaMESH:D010302 Parkinson|parkinsonismMESH:D010859 pigmentationMESH:D012120 respiratory syndromeMESH:D012128 acute respiratory distress syndrome|ARDSMESH:D012162 degeneration via microgliosisMESH:D012791 systems atrophies|degeneration in multiple systems atrophyMESH:D013167 SpondyloarthritisMESH:D013226 status epilepticusMESH:D013651 mitochondriopathy, dysfunction of metal homeostasisMESH:D014202 tremorMESH:D015526 HIV dementia|Parkinsonism in HIV dementia|AIDS Dementia ComplexMESH:D015658 HIV-infected|HIV infectionMESH:D016464 lysosomal disordersMESH:D018352 coronavirus diseaseMESH:D018476 bradykinesiaMESH:D019636 neurodegenerative disorders|neurodegenerative maladies|Neurodegeneration|neurodegenerative diseases|neurodegeneration|SN neurodegeneration|neurodegenerative disorderMESH:D020031 Epstein-BarrMESH:D020258 neurotoxic|neurotoxicityMESH:D020271 Neurological DiseasesMESH:D020521 strokesMESH:D020734 parkinsonian deficits|autosomal recessive parkinsonism|parkinsonian brains|Parkinson-like syndrome|parkinsonian|parkinsonian brainMESH:D020961 Lewy body disease|Lewy body diseasesMESH:D028361 mitochondrial deficits|mitochondrial dysfunction|Mitochondrial dysfunctionMESH:D030342 genetic defect|genetic abnormality|neuropathogenesis of the disorderMESH:D034721 system dysfunctionMESH:D057165 proteostasisMESH:D064420 cytotoxicity|toxicityMESH:D065703 Neuronal ApoptosisOMIM:256040 proteasomal dysfunction
Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19). Zubiaur P, et. al. (2020); Clin Transl Sci; 2020 Sep 16 . doi:10.1111/cts.12866
Multifactorial Rare Diseases: Can Uncertainty Analysis Bring Added Value to the Search for Risk Factors and Etiopathogenesis? Taruscio D, et. al. (2021); Medicina (Kaunas); 2021 Jan 28 ; 57 (2) . doi:10.3390/medicina57020119
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals. Zeberg H, et. al. (2021); Proc Natl Acad Sci U S A; 2021 Mar 02 ; 118 (9) . doi:10.1073/pnas.2026309118
Association of CXCR6 with COVID-19 severity: Delineating the host genetic factors in transcriptomic regulation. Dai Y, et. al. (2021); bioRxiv; 2021 Feb 19 . doi:10.1101/2021.02.17.431554
Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality. Nakanishi T, et. al. (2021); medRxiv; 2021 Mar 12 . doi:10.1101/2021.03.07.21252875
The landscape of host genetic factors involved in infection to common viruses and SARS-CoV-2. Kachuri L, et. al. (2020); medRxiv; 2020 May 30 . doi:10.1101/2020.05.01.20088054
Germline Genetic Variants of Viral Entry and Innate Immunity May Influence Susceptibility to SARS-CoV-2 Infection: Toward a Polygenic Risk Score for Risk Stratification. Grolmusz VK, et. al. (2021); Front Immunol; 2021 ; 12 653489. doi:10.3389/fimmu.2021.653489
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression. Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
Genetic susceptibility to infectious diseases: Current status and future perspectives from genome-wide approaches. Mozzi A, et. al. (2017); Infect. Genet. Evol.; 2017 Sep 22. doi:10.1016/j.meegid.2017.09.028
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control. Salpini R, et. al. (2021); J Antimicrob Chemother; 2021 01 19 ; 76 (2) 396-412. doi:10.1093/jac/dkaa444
Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19). Zubiaur P, et. al. (2020); Clin Transl Sci; 2020 Sep 16 . doi:10.1111/cts.12866
Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment. Al-Eitan LN, et. al. (2020); Rev Med Virol; 2020 Nov 17 2194. doi:10.1002/rmv.2194
Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19). Zubiaur P, et. al. (2020); Clin Transl Sci; 2020 Sep 16 . doi:10.1111/cts.12866
Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment. Al-Eitan LN, et. al. (2020); Rev Med Virol; 2020 Nov 17 2194. doi:10.1002/rmv.2194
Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection. Hashemi SMA, et. al. (2021); Arch Virol; 2021 May 02 . doi:10.1007/s00705-021-05070-6
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design. Sorokina M, et. al. (2020); Sci Data; 2020 09 16 ; 7 (1) 309. doi:10.1038/s41597-020-00652-6
Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19. Roy Wong LY, et. al. (2021); bioRxiv; 2021 Apr 21 . doi:10.1101/2021.04.20.440676
DNA genotyping of the ABO gene showed a significant association of the A-group (A1/A2 variants) with severe COVID-19. Gómez J, et. al. (2021); Eur J Intern Med; 2021 Feb 25 . doi:10.1016/j.ejim.2021.02.016
Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene Variants. Iyer GR, et. al. (2020); Front Genet; 2020 ; 11 861. doi:10.3389/fgene.2020.00861
Development and application of sensitive, specific and rapid CRISPR-Cas13-based diagnosis. Gao D, et. al. (2021); J Med Virol; 2021 Feb 18 . doi:10.1002/jmv.26889
Implications of SARS-CoV-2 Mutations for Genomic RNA Structure and Host microRNA Targeting. Hosseini Rad Sm A, et. al. (2020); Int J Mol Sci; 2020 Jul 07 ; 21 (13) . doi:10.3390/ijms21134807
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression. Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression. Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
Genetic deficiency and polymorphisms of cyclophilin A reveal its essential role for Human Coronavirus 229E replication. von Brunn A, et. al. (2015); Curr Opin Virol; 2015 Oct; 1456-61. doi:10.1016/j.coviro.2015.08.004
- MERS-CoV infectionsMESH:C000657245 CoV|SARS-CoV, HCoV-NL63|HCoV-NL63, HCoV-HKU1, SARS-CoV and MERS-CoV|coronaviruses SARS-CoV, HCoV-NL63|SARS-CoV and MERS-CoV viruses|SARS-CoV|CoV infectionMESH:C537931 pan-CoVMESH:D001102 viral infectionMESH:D002371 Feline CoV (FCoV) serotypes IMESH:D003324 coronary artery diseaseMESH:D003333 SARS-CoV, HCoV-229E|CoV-229E|HCoV-229E-LUC virus-infectedMESH:D006526 HCV infection|hepatitis C virus infectionMESH:D006528 hepatocellular carcinomaMESH:D007239 FCoV infection|infections|infectionMESH:D011014 pneumoniaMESH:D011488 CoV proteinsMESH:D012131 respiratory syndromeMESH:D012141 respiratory tract infections|infection of respiratory and gastrointestinalMESH:D014842 von Hahn|vonMESH:D015658 virus infectionMESH:D016766 Feline Infectious Peritonitis|CoV Feline Infectious Peritonitis VirusMESH:D018352 middle east respiratory syndrome coronavirus infection|middle East respiratory syndrome|coronavirus HKU1|coronavirus|SARS-coronavirus-host|coronavirus infection|Ausbruch von MERS-Coronavirus|Respiratory Syndrome Coronavirus|SARS coronavirus tightlyMESH:D030342 genetic deficiency|Genetic deficiencyMESH:D045169 Coronaviruses post-SARS
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression. Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression. Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
Will a little change do you good? A putative role of polymorphisms in COVID-19. Paim AAO, et. al. (2021); Immunol Lett; 2021 Apr 23 . doi:10.1016/j.imlet.2021.04.005
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression. Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression. Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
Development and application of sensitive, specific and rapid CRISPR-Cas13-based diagnosis. Gao D, et. al. (2021); J Med Virol; 2021 Feb 18 . doi:10.1002/jmv.26889
Molecular effects and retinopathy induced by hydroxychloroquine during SARS-CoV-2 therapy: Role of CYP450 isoforms and epigenetic modulations. Paniri A, et. al. (2020); Eur J Pharmacol; 2020 Nov 05 ; 886 173454. doi:10.1016/j.ejphar.2020.173454
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals. Zeberg H, et. al. (2021); Proc Natl Acad Sci U S A; 2021 Mar 02 ; 118 (9) . doi:10.1073/pnas.2026309118
Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection. Hashemi SMA, et. al. (2021); Arch Virol; 2021 May 02 . doi:10.1007/s00705-021-05070-6
COVID-19 one year into the pandemic: from genetics and genomics to therapy, vaccination, and policy. Novelli G, et. al. (2021); Hum Genomics; 2021 May 10 ; 15 (1) 27. doi:10.1186/s40246-021-00326-3
Effects of host genetic variations on response to, susceptibility and severity of respiratory infections. Ghafouri-Fard S, et. al. (2020); Biomed. Pharmacother.; 2020 Aug ; 128 110296. doi:10.1016/j.biopha.2020.110296
Potential immunomodulatory effects of vitamin D in the prevention of severe coronavirus disease 2019: An ally for Latin America (Review). Turrubiates-Hernández FJ, et. al. (2021); Int J Mol Med; 2021 04 ; 47 (4) . doi:10.3892/ijmm.2021.4865
The effect of angiotensin-converting enzyme levels on Covid-19 susceptibility and severity: a Mendelian randomization study. Butler-Laporte G, et. al. (2020); Int J Epidemiol; 2020 Dec 08 . doi:10.1093/ije/dyaa229
Germline Genetic Variants of Viral Entry and Innate Immunity May Influence Susceptibility to SARS-CoV-2 Infection: Toward a Polygenic Risk Score for Risk Stratification. Grolmusz VK, et. al. (2021); Front Immunol; 2021 ; 12 653489. doi:10.3389/fimmu.2021.653489
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals. Zeberg H, et. al. (2021); Proc Natl Acad Sci U S A; 2021 Mar 02 ; 118 (9) . doi:10.1073/pnas.2026309118
Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene Variants. Iyer GR, et. al. (2020); Front Genet; 2020 ; 11 861. doi:10.3389/fgene.2020.00861
Targeting Host Defense System and Rescuing Compromised Mitochondria to Increase Tolerance against Pathogens by Melatonin May Impact Outcome of Deadly Virus Infection Pertinent to COVID-19. Tan DX, et. al. (2020); Molecules; 2020 Sep 25 ; 25 (19) . doi:10.3390/molecules25194410
Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment. Al-Eitan LN, et. al. (2020); Rev Med Virol; 2020 Nov 17 2194. doi:10.1002/rmv.2194
Clinico-Biological Features and Clonal Hematopoiesis in Patients with Severe COVID-19. Duployez N, et. al. (2020); Cancers (Basel); 2020 Jul 21 ; 12 (7) . doi:10.3390/cancers12071992
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections. Egli A, et. al. (2014); Emerg Microbes Infect; 2014 Jul; 3(7) 51. doi:10.1038/emi.2014.51
MESH:C000657245 SARS-CoVMESH:C536528 van der WaalsMESH:C564133 atopyMESH:D001102 Viral infections|viral infection|viral tropism|Viral infection|viral infectionsMESH:D001249 asthmaMESH:D001327 autoimmune disease|autoimmune diseasesMESH:D001424 bacterial infectionsMESH:D003141 Infectious diseases|infectious diseasesMESH:D003586 cytomegalovirus infectionMESH:D004342 allergic airway diseaseMESH:D005767 gastrointestinalMESH:D006509 hepatitis BMESH:D006526 hepatitis C viral|hepatitis C|hepatitis C virus infections|HCV-infected|chronic HCV infection|Sendai virusand hepatitis C virus|hepatitis C virus-infected|impaired clearance of hepatitis C|HCV infection|hepatitis C virus 1B infection|HIV/HCV co-infected|hepatitis C virus infectionMESH:D006528 hepatomaMESH:D007239 CMV-infected|infectionMESH:D007249 inflammationMESH:D007251 influenza A virus infectionMESH:D007674 embryonic kidneyMESH:D008171 infection of lung|lung diseasesMESH:D008180 systemic lupus erythematosusMESH:D009103 multiple sclerosisMESH:D011565 psoriasisMESH:D014766 CMV viremiaMESH:D015179 CMV infection increases colonicMESH:D015458 T-cell leukemia virus type-1 mono-infectionMESH:D015658 HIV/HCV-coinfected|Hantaan virus infection|HIV|Virus infection|HIV-1 coinfected|immunodeficiency virus type 1 infectionMESH:D018352 respiratory syndrome coronavirusMESH:D019698 chronic hepatitis C virus infection|chronic hepatitis C|chronic hepatitis C viral infection|chronic hepatitis C virus type 1 infection|acute hepatitis CMESH:D020336 spastic paraparesisMESH:D056486 posttransplant hepatitis c infection|liver damage|hepatitisMESH:D059787 acute virus infectionMESH:D060085 HCV-coinfected
Potential immunomodulatory effects of vitamin D in the prevention of severe coronavirus disease 2019: An ally for Latin America (Review). Turrubiates-Hernández FJ, et. al. (2021); Int J Mol Med; 2021 04 ; 47 (4) . doi:10.3892/ijmm.2021.4865
Naringerin as candidate drug against SARS-CoV-2: The role for TPC2 genomic variants in COVID-19. Di Maria E, et. al. (2020); Pharmacol Res; 2020 Dec 24 105402. doi:10.1016/j.phrs.2020.105402
Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene Variants. Iyer GR, et. al. (2020); Front Genet; 2020 ; 11 861. doi:10.3389/fgene.2020.00861
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections. Egli A, et. al. (2014); Emerg Microbes Infect; 2014 Jul; 3(7) 51. doi:10.1038/emi.2014.51
MESH:C000657245 SARS-CoVMESH:C536528 van der WaalsMESH:C564133 atopyMESH:D001102 Viral infections|viral infection|viral tropism|Viral infection|viral infectionsMESH:D001249 asthmaMESH:D001327 autoimmune disease|autoimmune diseasesMESH:D001424 bacterial infectionsMESH:D003141 Infectious diseases|infectious diseasesMESH:D003586 cytomegalovirus infectionMESH:D004342 allergic airway diseaseMESH:D005767 gastrointestinalMESH:D006509 hepatitis BMESH:D006526 hepatitis C viral|hepatitis C|hepatitis C virus infections|HCV-infected|chronic HCV infection|Sendai virusand hepatitis C virus|hepatitis C virus-infected|impaired clearance of hepatitis C|HCV infection|hepatitis C virus 1B infection|HIV/HCV co-infected|hepatitis C virus infectionMESH:D006528 hepatomaMESH:D007239 CMV-infected|infectionMESH:D007249 inflammationMESH:D007251 influenza A virus infectionMESH:D007674 embryonic kidneyMESH:D008171 infection of lung|lung diseasesMESH:D008180 systemic lupus erythematosusMESH:D009103 multiple sclerosisMESH:D011565 psoriasisMESH:D014766 CMV viremiaMESH:D015179 CMV infection increases colonicMESH:D015458 T-cell leukemia virus type-1 mono-infectionMESH:D015658 HIV/HCV-coinfected|Hantaan virus infection|HIV|Virus infection|HIV-1 coinfected|immunodeficiency virus type 1 infectionMESH:D018352 respiratory syndrome coronavirusMESH:D019698 chronic hepatitis C virus infection|chronic hepatitis C|chronic hepatitis C viral infection|chronic hepatitis C virus type 1 infection|acute hepatitis CMESH:D020336 spastic paraparesisMESH:D056486 posttransplant hepatitis c infection|liver damage|hepatitisMESH:D059787 acute virus infectionMESH:D060085 HCV-coinfected
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections. Egli A, et. al. (2014); Emerg Microbes Infect; 2014 Jul; 3(7) 51. doi:10.1038/emi.2014.51
MESH:C000657245 SARS-CoVMESH:C536528 van der WaalsMESH:C564133 atopyMESH:D001102 Viral infections|viral infection|viral tropism|Viral infection|viral infectionsMESH:D001249 asthmaMESH:D001327 autoimmune disease|autoimmune diseasesMESH:D001424 bacterial infectionsMESH:D003141 Infectious diseases|infectious diseasesMESH:D003586 cytomegalovirus infectionMESH:D004342 allergic airway diseaseMESH:D005767 gastrointestinalMESH:D006509 hepatitis BMESH:D006526 hepatitis C viral|hepatitis C|hepatitis C virus infections|HCV-infected|chronic HCV infection|Sendai virusand hepatitis C virus|hepatitis C virus-infected|impaired clearance of hepatitis C|HCV infection|hepatitis C virus 1B infection|HIV/HCV co-infected|hepatitis C virus infectionMESH:D006528 hepatomaMESH:D007239 CMV-infected|infectionMESH:D007249 inflammationMESH:D007251 influenza A virus infectionMESH:D007674 embryonic kidneyMESH:D008171 infection of lung|lung diseasesMESH:D008180 systemic lupus erythematosusMESH:D009103 multiple sclerosisMESH:D011565 psoriasisMESH:D014766 CMV viremiaMESH:D015179 CMV infection increases colonicMESH:D015458 T-cell leukemia virus type-1 mono-infectionMESH:D015658 HIV/HCV-coinfected|Hantaan virus infection|HIV|Virus infection|HIV-1 coinfected|immunodeficiency virus type 1 infectionMESH:D018352 respiratory syndrome coronavirusMESH:D019698 chronic hepatitis C virus infection|chronic hepatitis C|chronic hepatitis C viral infection|chronic hepatitis C virus type 1 infection|acute hepatitis CMESH:D020336 spastic paraparesisMESH:D056486 posttransplant hepatitis c infection|liver damage|hepatitisMESH:D059787 acute virus infectionMESH:D060085 HCV-coinfected
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections. Egli A, et. al. (2014); Emerg Microbes Infect; 2014 Jul; 3(7) 51. doi:10.1038/emi.2014.51
MESH:C000657245 SARS-CoVMESH:C536528 van der WaalsMESH:C564133 atopyMESH:D001102 Viral infections|viral infection|viral tropism|Viral infection|viral infectionsMESH:D001249 asthmaMESH:D001327 autoimmune disease|autoimmune diseasesMESH:D001424 bacterial infectionsMESH:D003141 Infectious diseases|infectious diseasesMESH:D003586 cytomegalovirus infectionMESH:D004342 allergic airway diseaseMESH:D005767 gastrointestinalMESH:D006509 hepatitis BMESH:D006526 hepatitis C viral|hepatitis C|hepatitis C virus infections|HCV-infected|chronic HCV infection|Sendai virusand hepatitis C virus|hepatitis C virus-infected|impaired clearance of hepatitis C|HCV infection|hepatitis C virus 1B infection|HIV/HCV co-infected|hepatitis C virus infectionMESH:D006528 hepatomaMESH:D007239 CMV-infected|infectionMESH:D007249 inflammationMESH:D007251 influenza A virus infectionMESH:D007674 embryonic kidneyMESH:D008171 infection of lung|lung diseasesMESH:D008180 systemic lupus erythematosusMESH:D009103 multiple sclerosisMESH:D011565 psoriasisMESH:D014766 CMV viremiaMESH:D015179 CMV infection increases colonicMESH:D015458 T-cell leukemia virus type-1 mono-infectionMESH:D015658 HIV/HCV-coinfected|Hantaan virus infection|HIV|Virus infection|HIV-1 coinfected|immunodeficiency virus type 1 infectionMESH:D018352 respiratory syndrome coronavirusMESH:D019698 chronic hepatitis C virus infection|chronic hepatitis C|chronic hepatitis C viral infection|chronic hepatitis C virus type 1 infection|acute hepatitis CMESH:D020336 spastic paraparesisMESH:D056486 posttransplant hepatitis c infection|liver damage|hepatitisMESH:D059787 acute virus infectionMESH:D060085 HCV-coinfected