Researchtool

Genetic factors influencing the course of SARS-CoV-2 infection.

Overview of variants in dbSNP annotated in Pubtator with MESH terms filtered by the term “SARS-CoV”.

EPI-Dx - ATLAS Biolabs GmbH
ATLAS Biolabs GmbH - Molekulargenetische Analysen - Molecular genetic analyses
Data sourcesInfoProcessing time: Thu, 3. Jun. 2021 - 17:09:09 - Thu, 3. Jun. 2021 - 17:34:22
  • Search term: SARS-CoV
  • Genes: 1135
  • Mutations: 3534
  • Affy IDs: 964 on Microarray Axiom HGCoV-2

Enter Pubmed IDs seperated by comma:

Mutation - Affy ID Ref/Alt Gene Entrez Chr:Pos Cnt Publication
rs#2660
/
: 1
 15766558
Polymorphisms of interferon-inducible genes OAS-1 and MxA associated with SARS in the Vietnamese population.
Hamano E, et. al. (2005); Biochem. Biophys. Res. Commun.; 2005 Apr 22; 329(4) 1234-9
MESH:C000657245 SARS-CoV Ab|SARS-CoV infection|SARS-CoV infected|SARS-CoV
MESH:C537769 OAS-1 SARS infected
MESH:C580335 Non-hypoxemic
MESH:D000860 hypoxemia
MESH:D001102 viral infection|viral infections
MESH:D003141 infectious disease
MESH:D003920 diabetes mellitus
MESH:D006525 viral hepatitis
MESH:D006526 HCV infection|hepatitis C virus (HCV) infection|hepatitis C viral infection|hepatitis C virus infection
MESH:D007938 leukemia
MESH:D012131 respiratory syndrome
MESH:D015658 virus infection
MESH:D018352 coronavirus|respiratory syndrome coronavirus|respiratory syndrome coronavirus infection|Coronavirus|SARS coronavirus infection|SARS-associated coronavirus (SCOV) infection
MESH:D019698 chronic hepatitis C
MESH:D020022
MESH:D045169 SARS|SARS infected|hypoxemic SARS|non-hypoxemic SARS|SARS infection
rs10002395
T/G
GYPB 2994 4:144011706 1
 33981715
How Genetics Might Explain the Unusual Link Between Malaria and COVID-19.
Rusmini M, et. al. (2021); Front Med (Lausanne); 2021 ; 8 650231. doi:10.3389/fmed.2021.650231
MESH:C000657245 covid-19|COVID-19 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|malaria-COVID-19|COVID19|SARS-CoV-2 infections|2019 and malaria|COVID-19|new coronavirus disease|SARS-CoV-2 pneumonia|coronavirus 2 infection|covid|covid_19|Covid-19|CoV-2 infections
MESH:C536778 Carnitine deficiency
MESH:D000163 AIDS
MESH:D000740 anemia|malaria anemia
MESH:D001102 virus infection|viral infections
MESH:D001201 ascites of MethA sarcoma
MESH:D001281 AF
MESH:D002100 cachexia
MESH:D003643 mortality|deaths|deaths for malaria
MESH:D005221 fatigue
MESH:D005334 malarial fever|fever
MESH:D005955 G6PD deficiency GNAS
MESH:D006261 headache
MESH:D006528 hepatoma
MESH:D006973 Hypertension|hypertension-malaria|hypertension
MESH:D007239 malarial infection|falciparum infection|infections|Falciparum infection|infected|infection
MESH:D007249 inflammation
MESH:D008171 eQTLs slope lung eQTL
MESH:D008175 lung carcinoma
MESH:D008286 malabsorption
MESH:D008288 malaria HBB|malaria infections|malaria parasites|Malaria|malaria parasite|malaria|malaria infection|malaria GYPC
MESH:D008661 Inborn errors of type I
MESH:D009080 kawasaki disease|Kawasaki disease
MESH:D009369 cancer|tumor
MESH:D010272 malarial parasites
MESH:D011014 lung inflammation
MESH:D012131 respiratory failure
MESH:D014947 endothelial injury
MESH:D015658 HIV
MESH:D016778 Falciparum parasitaemia
MESH:D016779 cerebral malaria
MESH:D018352 coronavirus disease
MESH:D020258 neurotoxicity
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D060085 secondary carnitine deficiency syndromes
rs1001881892
A/G
SH2D3C 10044 9:127758297 1
 32577641
Sarbecovirus comparative genomics elucidates gene content of SARS-CoV-2 and functional impact of COVID-19 pandemic mutations.
Jungreis I, et. al. (2020); bioRxiv; 2020 Jun 03 . doi:10.1101/2020.06.02.130955
MESH:C000657245 SARS-CoV-2 infected|COVID-19
MESH:D001102 virus-infected
MESH:D001750 embryonic neurogenesis
MESH:D004474 hypothetical ORFs
MESH:D012140 respiratory disease
rs1002211420
G/A,C
BMP2K 55589 4:78833675 1
 33187978
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.
Stebbing J, et. al. (2021); Sci Adv; 2021 01 ; 7 (1) . doi:10.1126/sciadv.abe4724
MESH:C000657245 SARS-CoV-2 pneumonia|COVID-19 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|2019-nCoV acute respiratory disease|SARS-CoV-2 infections|SARS-CoV-2-infected|Covid-19|COVID-19|COVID
MESH:C536439 endotheliitis
MESH:D000370 Ageusia/anosmia
MESH:D001102 viral infection|viral infections
MESH:D001145 arrhythmias
MESH:D001168 arthritis
MESH:D001172 adult rheumatoid arthritis|rheumatoid arthritis|RA
MESH:D001281 atrial fibrillation
MESH:D001748 urinary obstruction
MESH:D001778 coagulopathy|coagulation
MESH:D002177 candidiasis
MESH:D002318 Cardiovascular disease|CVD|cardiovascular disease
MESH:D002908 Chronic obstructivelung disease
MESH:D003139 common cold
MESH:D003141 infectious disease
MESH:D003371 Cough
MESH:D003643 Died|mortality|Mortality|died|death
MESH:D003920 diabetes mellitus|Diabetes
MESH:D003967 diarrhea|Diarrhea
MESH:D004417 Dyspnea
MESH:D005334 Fever
MESH:D006261 Headache
MESH:D006331 heart disease
MESH:D006333 heart failure
MESH:D006471 gastrointestinal bleed
MESH:D006528 hepatocellular carcinoma
MESH:D006561 facial herpes simplex infection
MESH:D006973 Hypertension|hypertension|hypertensive
MESH:D007154 immune dysfunction
MESH:D007239 infections|infection|infected
MESH:D007249 inflammation
MESH:D007676 Chronic kidney failure|chronic kidney failure
MESH:D008171 lung damage
MESH:D008231 lymphocytopenia
MESH:D008661 Inborn errors of type I
MESH:D009102 organ failure
MESH:D009325 nausea
MESH:D009369 Cancer|cancer
MESH:D009393 nephritis
MESH:D011014 pneumonia
MESH:D011471 malignant prostate
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure
MESH:D013274 gastric malignancy
MESH:D013923 Thromboembolism
MESH:D013927 thrombotic|thrombosis
MESH:D014552 urinary tract infections
MESH:D014839 vomiting
MESH:D016470 bacteremia
MESH:D016638 critically ill
MESH:D017093 Liver spheroids|liver injury|liver spheroid|Liver injury
MESH:D018352 Coronavirus infections
MESH:D018980 Williams E
MESH:D019965 neurocognitive disorders
MESH:D025861 Coagulation abnormalities
MESH:D029424 chronic obstructive pulmonary disease|COPD
MESH:D029461 SD
MESH:D051436 Chronic kidney disease
MESH:D053632 SCID
MESH:D055370 lung injury
MESH:D055985 latent tuberculosis infection
MESH:D056486 endotheliitis and liver injury|liver function abnormalities|liver function and disease
MESH:D057049 thrombotic microangiopathy
MESH:D057772 Pulmonary vascular endothelialitis|vascular endotheliitis
MESH:D058625 Chronic liver injury
MESH:D064420 toxicity|toxicities
rs10025455
C/G
GYPB 2994 4:143998417 1
 33981715
How Genetics Might Explain the Unusual Link Between Malaria and COVID-19.
Rusmini M, et. al. (2021); Front Med (Lausanne); 2021 ; 8 650231. doi:10.3389/fmed.2021.650231
MESH:C000657245 covid-19|COVID-19 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|malaria-COVID-19|COVID19|SARS-CoV-2 infections|2019 and malaria|COVID-19|new coronavirus disease|SARS-CoV-2 pneumonia|coronavirus 2 infection|covid|covid_19|Covid-19|CoV-2 infections
MESH:C536778 Carnitine deficiency
MESH:D000163 AIDS
MESH:D000740 anemia|malaria anemia
MESH:D001102 virus infection|viral infections
MESH:D001201 ascites of MethA sarcoma
MESH:D001281 AF
MESH:D002100 cachexia
MESH:D003643 mortality|deaths|deaths for malaria
MESH:D005221 fatigue
MESH:D005334 malarial fever|fever
MESH:D005955 G6PD deficiency GNAS
MESH:D006261 headache
MESH:D006528 hepatoma
MESH:D006973 Hypertension|hypertension-malaria|hypertension
MESH:D007239 malarial infection|falciparum infection|infections|Falciparum infection|infected|infection
MESH:D007249 inflammation
MESH:D008171 eQTLs slope lung eQTL
MESH:D008175 lung carcinoma
MESH:D008286 malabsorption
MESH:D008288 malaria HBB|malaria infections|malaria parasites|Malaria|malaria parasite|malaria|malaria infection|malaria GYPC
MESH:D008661 Inborn errors of type I
MESH:D009080 kawasaki disease|Kawasaki disease
MESH:D009369 cancer|tumor
MESH:D010272 malarial parasites
MESH:D011014 lung inflammation
MESH:D012131 respiratory failure
MESH:D014947 endothelial injury
MESH:D015658 HIV
MESH:D016778 Falciparum parasitaemia
MESH:D016779 cerebral malaria
MESH:D018352 coronavirus disease
MESH:D020258 neurotoxicity
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D060085 secondary carnitine deficiency syndromes
rs1003253923
C/T
CA4 762 17:60168125 1
 32513865
Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California.
Deng X, et. al. (2020); Science; 2020 07 31 ; 369 (6503) 582-587. doi:10.1126/science.abb9263
MESH:C000657245 SARS-CoV-2 infected|coronavirus disease 2019|Coronavirus Disease 2019|COVID-19
MESH:D001102 virus disease
MESH:D003643 deaths
MESH:D007239 infections|infected|infection
MESH:D011014 pneumonia
MESH:D015047 zoonotic
OMIM:176500 British Columbia
rs10044354
C/T
LNPEP 4012 5:96984791 1
 33262772
HLA-A29 and Birdshot Uveitis: Further Down the Rabbit Hole.
Kuiper JJW, et. al. (2020); Front Immunol; 2020 ; 11 599558. doi:10.3389/fimmu.2020.599558
MESH:C000657245 SARS-CoV-2 Infection
MESH:C562393 Skin Cutaneous Melanoma
MESH:C564616 tissue-resident memory T(H)17
MESH:D000080365 Birdshot chorioretinopathy|Retinochoroiditis|birdshot retinopathy|Birdshot Retinochoroiditis|birdshot chorioretinitis|Birdshot Chorioretinitis|Birdshot retinochoroidopathy|Birdshot Chorioretinopathy|birdshot retinochoroidopathy|birdshot chorioretinopathy|Birdshot Retinochoroidopathy|Birdshot chorioretinopathy or Birdshot retinochoroidopathy|birdshot retinochoroiditis|Familial Birdshot Chorioretinopathy
MESH:D000853 eye disease
MESH:D001172 Rheumatoid Arthritis
MESH:D001327 autoimmune kidney disease|autoimmune disease|Endocrine Autoimmune Disease|autoimmune disease of the kidney
MESH:D002609 CHS
MESH:D002833 stromal choroiditis|loss of choroidal|Stromal Choroiditis|choroidal stroma|eye choroid
MESH:D003103 uveoretinitis
MESH:D004487 edema
MESH:D005598 Spontaneous retinopathy
MESH:D006505 chronic hepatitis
MESH:D007239 infected|infection
MESH:D007249 choroidal inflammation|inflammation of the choroidal stroma|inflammation spilling|Inflammation|eye inflammation|inflammatory disorders|inflammation|retinal inflammation
MESH:D007511 ischemia
MESH:D007625 degeneration of the retina
MESH:D008180 systemic lupus erythema
MESH:D008269 cystoid macular edema
MESH:D008527 medulloblastoma
MESH:D008545 melanoma|Melanoma|melanoma tumor|malignant melanoma|melanoma immunoreactivity
MESH:D009369 cancerous|cancer|tumor|melanoma cancer|tumors
MESH:D009461 dysfunctional
MESH:D009471 Neuromyelitis optica
MESH:D009798 Intraocular candidiasis
MESH:D010859 pigmented
MESH:D011014 inflammatory lung disease|Pulmonary Inflammation
MESH:D011565 psoriasis
MESH:D012162 degeneration
MESH:D012164 retinal disease|Chorioretinopathy|retinal degenerative disease
MESH:D012173 birdshot retinitis
MESH:D012216 rheumatic disease
MESH:D012640 fits
MESH:D013167 Spondyloarthritis|ankylosing spondylitis|Ankylosing Spondylitis
MESH:D014605 birdshot uveitis|Autoimmune Uveitis|Birdshot Uveitis|autoimmune uveitis|uveitis|Uveitis
MESH:D014606 anterior uveitis|Acute Anterior Uveitis
MESH:D014607 Vogt-Koyanagi-Harada Disease|Vogt-Koyanagi-Harada disease|Harada (VKH) disease
MESH:D015179 colorectal tumor
MESH:D015212 inflammatory bowel disease
MESH:D019572 retina involvement
MESH:D056660 autoinflammatory disease
MESH:D058387 candidemia
MESH:D064806 dysbiosis
rs1005074063
G/A
SH2D3C 10044 9:127767176 2
 32742035
Variant analysis of SARS-CoV-2 genomes.
Koyama T, et. al. (2020); Bull World Health Organ; 2020 Jul 01 ; 98 (7) 495-504. doi:10.2471/BLT.20.253591
MESH:C000657245 novel infections|covid-19|SARS-CoV-2 pneumonia|coronavirus disease 2019|novel coronavirus pneumonia|COVID-19
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004417 shortness of breath
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D007239 infected
MESH:D009765 obesity
MESH:D011014 pneumonia
MESH:D012140 respiratory disease
MESH:D014786 loss
MESH:D015047 zoonotic
MESH:D016638 critically ill
MESH:D018352 Coronavirus disease
MESH:D055370 chronic lung disease
 33637820
Hospitalization and mortality associated with SARS-CoV-2 viral clades in COVID-19.
Nakamichi K, et. al. (2021); Sci Rep; 2021 02 26 ; 11 (1) 4802. doi:10.1038/s41598-021-82850-9
MESH:C000657245 SARS-CoV-2 infection|Covid-19|COVID-19|COVID
MESH:D002318 CVD|Cardiovascular Diseaseb|cardiovascular disease|Cardiovascular Diseasea
MESH:D003141 cCardiovascular disease|aCardiovascular disease|bCardiovascular disease
MESH:D003643 mortality|Death|deaths|death
MESH:D003920 diabetes|Diabetes
MESH:D006333 Heart Failure|Chronic Heart Failure
MESH:D006349 valvular diseases
MESH:D006973 Hypertension|hypertension
MESH:D007037 Hypothyroid
MESH:D007239 infections|infected|infection
MESH:D009203 MI myocardial infarction
MESH:D009369 Cancer|malignancy|cancer
MESH:D011014 pneumonia
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D016638 critically ill
MESH:D018352 MERS
MESH:D020246 deep venous thrombosis|DVT Deep Venous Thrombosis
MESH:D020521 stroke
MESH:D029424 COPD chronic obstructive pulmonary disease|COPD
MESH:D051436 Chronic Kidney Disease 15|Chronic Kidney Disease|chronic renal disease
MESH:D056486 hepatic disease
MESH:D058540 AIC
rs10050860 Affx-27211195
C/T
ERAP1 51752 5:96786506 1
 33567739
ERAP1 and ERAP2 Enzymes: A Protective Shield for RAS against COVID-19?
D'Amico S, et. al. (2021); Int J Mol Sci; 2021 Feb 08 ; 22 (4) . doi:10.3390/ijms22041705
MESH:C000657245 CoV-2 infection|COVID-19 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|COVID-19 coronavirus disease|Covid-19|COVID-19
MESH:D000079225 Stress
MESH:D000783 vascular damage
MESH:D001102 virus-infected|viral infections
MESH:D001327 autoimmune disease|autoimmune diseases|Autoimmune disease
MESH:D002312 ventricular hypertrophy
MESH:D002318 cardiovascular disease
MESH:D003141 Infectious Diseases|MAF Disease
MESH:D003643 mortality|deaths|death
MESH:D003920 diabetes
MESH:D005355 fibrosis|Fibrosis
MESH:D006973 Hypertension|hypertension|hypertensive|Hypertensive
MESH:D007008 hypokalemia
MESH:D007022 hypotension
MESH:D007239 Infection|infection|infected
MESH:D007249 inflammatory disorders|inflammation
MESH:D008661 Inborn errors of type I
MESH:D009102 multi-organ dysfunction
MESH:D009336 TNFalpha tumor necrosis
MESH:D009369 cancer|tumor
MESH:D009447 neuroblastoma
MESH:D009461 dysfunctional
MESH:D009765 obesity
MESH:D012120 respiratory syndrome
MESH:D012131 Respiratory Failure|respiratory failure
MESH:D015658 HIV-1 Infection
MESH:D018352 Coronavirus infections
MESH:D055370 lung injury|pulmonary injury
MESH:D055371 acute lung failure
rs10069690 Affx-25654623
C/T
TERT 7015 5:1279675 1
 26621837
Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations.
Zhang Y, et. al. (2016); Oncotarget; 2016 Jan 05; 7(1) 759-70. doi:10.18632/oncotarget.6397
MESH:C000657245 SARS-CoV infection
MESH:C562393 cutaneous melanoma
MESH:D000077274 nasopharyngeal carcinomas|nasopharyngeal carcinoma
MESH:D000230 adenocarcinoma
MESH:D001943 breast cancer
MESH:D002280 basal cell carcinoma
MESH:D002294 squamous cell carcinoma
MESH:D002583 cervical cancers
MESH:D002971 cleft lip palate
MESH:D003316 congenital corneal diseases
MESH:D005910 glioma
MESH:D006509 Hepatitis B virus (HBV) infection
MESH:D006528 hepatocellular carcinoma
MESH:D007105 complex disease
MESH:D008175 lung cancer|lung tumors|GWAS of lung cancer
MESH:D008545 melanoma
MESH:D009303
MESH:D009362 tumor-node-metastasis
MESH:D009369 Cancer|non-tumor|tumor|tumors|malignancy|cancer|cancers|Guangxi Cancer
MESH:D010051 serous ovarian|ovary cancer|ovarian tumor|serous ovarian cancer
MESH:D010190 pancreatic cancer
MESH:D010195 pancreatic
MESH:D011471 prostate cancers
MESH:D015179 colorectal cancer|colon cancer|colorectal cancers
MESH:D015451 chronic lymphocytic leukemia
MESH:D016889 endometrial cancer|endometrial cancers
MESH:D020022
MESH:D020031 Epstein-Barr virus infection
MESH:D052556 NPC carcinogenesis
MESH:D063646 carcinogenesis
rs10073340
C/T
CLPTM1L 81037 5:1321758 1
 26621837
Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations.
Zhang Y, et. al. (2016); Oncotarget; 2016 Jan 05; 7(1) 759-70. doi:10.18632/oncotarget.6397
MESH:C000657245 SARS-CoV infection
MESH:C562393 cutaneous melanoma
MESH:D000077274 nasopharyngeal carcinomas|nasopharyngeal carcinoma
MESH:D000230 adenocarcinoma
MESH:D001943 breast cancer
MESH:D002280 basal cell carcinoma
MESH:D002294 squamous cell carcinoma
MESH:D002583 cervical cancers
MESH:D002971 cleft lip palate
MESH:D003316 congenital corneal diseases
MESH:D005910 glioma
MESH:D006509 Hepatitis B virus (HBV) infection
MESH:D006528 hepatocellular carcinoma
MESH:D007105 complex disease
MESH:D008175 lung cancer|lung tumors|GWAS of lung cancer
MESH:D008545 melanoma
MESH:D009303
MESH:D009362 tumor-node-metastasis
MESH:D009369 Cancer|non-tumor|tumor|tumors|malignancy|cancer|cancers|Guangxi Cancer
MESH:D010051 serous ovarian|ovary cancer|ovarian tumor|serous ovarian cancer
MESH:D010190 pancreatic cancer
MESH:D010195 pancreatic
MESH:D011471 prostate cancers
MESH:D015179 colorectal cancer|colon cancer|colorectal cancers
MESH:D015451 chronic lymphocytic leukemia
MESH:D016889 endometrial cancer|endometrial cancers
MESH:D020022
MESH:D020031 Epstein-Barr virus infection
MESH:D052556 NPC carcinogenesis
MESH:D063646 carcinogenesis
rs10078761
T/A
SLC6A18 348932 5:1249479 1
 26621837
Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations.
Zhang Y, et. al. (2016); Oncotarget; 2016 Jan 05; 7(1) 759-70. doi:10.18632/oncotarget.6397
MESH:C000657245 SARS-CoV infection
MESH:C562393 cutaneous melanoma
MESH:D000077274 nasopharyngeal carcinomas|nasopharyngeal carcinoma
MESH:D000230 adenocarcinoma
MESH:D001943 breast cancer
MESH:D002280 basal cell carcinoma
MESH:D002294 squamous cell carcinoma
MESH:D002583 cervical cancers
MESH:D002971 cleft lip palate
MESH:D003316 congenital corneal diseases
MESH:D005910 glioma
MESH:D006509 Hepatitis B virus (HBV) infection
MESH:D006528 hepatocellular carcinoma
MESH:D007105 complex disease
MESH:D008175 lung cancer|lung tumors|GWAS of lung cancer
MESH:D008545 melanoma
MESH:D009303
MESH:D009362 tumor-node-metastasis
MESH:D009369 Cancer|non-tumor|tumor|tumors|malignancy|cancer|cancers|Guangxi Cancer
MESH:D010051 serous ovarian|ovary cancer|ovarian tumor|serous ovarian cancer
MESH:D010190 pancreatic cancer
MESH:D010195 pancreatic
MESH:D011471 prostate cancers
MESH:D015179 colorectal cancer|colon cancer|colorectal cancers
MESH:D015451 chronic lymphocytic leukemia
MESH:D016889 endometrial cancer|endometrial cancers
MESH:D020022
MESH:D020031 Epstein-Barr virus infection
MESH:D052556 NPC carcinogenesis
MESH:D063646 carcinogenesis
rs10080 Affx-3101209
G/A
NRP1 8829 10:33178180 1
 33934196
Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection.
Hashemi SMA, et. al. (2021); Arch Virol; 2021 May 02 . doi:10.1007/s00705-021-05070-6
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV infection|COVID19|SARS-CoV-2 infections|novel coronavirus pneumonia|CoV-2 infection|novel coronavirus infections|SARS-CoV-2-infected|COVID-19|new coronavirus disease|SARS-CoV-1 infection Itoyama|Coronavirus disease 2019|2019 infection|SARS-CoV-1 infection outcome Patarcic|SARS-CoV-1 infection|Covid-19|coronavirus disease-2019
MESH:C535882 Johnson L
MESH:C536174 panbronchiolitis
MESH:C538614 renal cell carcinoma
MESH:C564969 multi-organ disease
MESH:C567355 immunodeficiency virus-mediated syncytia
MESH:D000544 Alzheimer's disease|Alzheimer disease
MESH:D000860 hypoxemia|hypoxia
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001424 bacterial infections
MESH:D001847 bone homeostasis
MESH:D001943 breast cancer
MESH:D002318 cardiovascular disease|cardiovascular systems|cardiovascular diseases
MESH:D002537 atherosclerotic cerebral infarction
MESH:D002544 acute cerebral infarction
MESH:D002908 rhinovirus illness
MESH:D003141 atherothrombotic disease|infectious diseases
MESH:D003428 nosocomial infection
MESH:D003643 mortality|deaths|mortalities|death|mortal
MESH:D003920 diabetes|diabetes mellitus
MESH:D003924 type 2 diabetes|type 2 diabetes mellitus
MESH:D004194 multiple diseases and disorders|numerous diseases and disorders
MESH:D004487 alveolar edema
MESH:D004646 emphysema
MESH:D004675 tick-borne encephalitis
MESH:D005355 fibrosis
MESH:D005921 glomerulosclerosis
MESH:D006331 congenital heart disease
MESH:D006333 heart failure
MESH:D006461 hemolysis
MESH:D006509 hepatitis B virus infection|hepatitis B
MESH:D006526 HCV infection|hepatitis C virus (HCV) infection|hepatitis C virus infection|hepatitis C viral infection
MESH:D006973 hypertension|hypertensive
MESH:D007239 Decreased infection|infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 Collapsing glomerulopathy|kidney disease|nondiabetic nephropathy|glomerulopathy
MESH:D008103 hepatic fibrosis
MESH:D008171 pulmonary damage|lung disease|lung damage
MESH:D008288 malaria parasites
MESH:D008545 melanoma|malignant melanoma
MESH:D008659 metabolic disorders
MESH:D008661 Inborn errors of type I
MESH:D009103 multiple sclerosis
MESH:D009336 tumour necrosis
MESH:D009362 metastasis of tumors
MESH:D009369 cancerous|cancer|cancers|tumor|carcinoma
MESH:D009393 nephritis
MESH:D010051 ovaries
MESH:D010190 invasiveness of pancreatic cancer
MESH:D010300 PD
MESH:D011014 pneumonia|lung inflammation
MESH:D011471 prostate cancer metastasis|NCI-H660 prostate cancer|prostate cancer|aggressive prostate cancer|sporadic prostate cancer
MESH:D011565 psoriasis
MESH:D011654 pulmonary edema
MESH:D011658 pulmonary fibrosis
MESH:D011660 hypoxaemic cor pulmonale
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome|ARDS|adult respiratory distress syndrome
MESH:D012131 respiratory failure|pulmonary failure
MESH:D012140 chronic respiratory disease|respiratory disease
MESH:D012141 respiratory viruses infections|upper respiratory tract infections
MESH:D012598 sclerosis
MESH:D012769 shock
MESH:D012871 skin diseases
MESH:D013927 thrombotic
MESH:D015140 vascular dementia
MESH:D015179 colorectal cancer
MESH:D015619 respiratory system edema
MESH:D015658 HIV infection|HIV-1 infection
MESH:D016638 critical illness|critically ill
MESH:D018352 MERS-CoV infection|respiratory syndrome coronavirus infection|coronavirus disease|SARS coronavirus infection|CoV-1 infection|coronavirus infection|Coronavirus infection|Middle East respiratory syndrome-coronavirus infection
MESH:D019698 chronic hepatitis C virus infection
MESH:D020258 neurotoxicity
MESH:D045169 severe acute respiratory syndrome|SARS infection
MESH:D050197 atherosclerotic|atherosclerosis|atherosclerotic lesions
MESH:D051436 chronic kidney disease
MESH:D054058 acute coronary syndrome
MESH:D054990 idiopathic pulmonary fibrosis
MESH:D055370 lung injury
MESH:D055371 acute lung failure|acute lung injury
MESH:D058186 Acute kidney injury
MESH:D059446 asplenia
rs10082466
A/G
MBL2 4153 10:52766862 1
 33681468
MBL2 polymorphisms in a variety of infectious diseases by the future studies.">The ambiguous role of mannose-binding lectin (MBL) in human immunity.
Kalia N, et. al. (2021); Open Med (Wars); 2021 ; 16 (1) 299-310. doi:10.1515/med-2021-0239
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 lung injury|COVID-19|SARS-CoV-1 infection|COVID
MESH:C562390 humoral immunodeficiencies
MESH:C563602 MBL2 deficiency|MBL deficiency|MBL-deficient
MESH:D000014 opsonic defect
MESH:D000163 AIDS
MESH:D000309 insufficiency
MESH:D000740 anemia
MESH:D001102 viral infection
MESH:D001172 rheumatoid arthritis
MESH:D001327 autoimmune diseases
MESH:D001943 breast cancer
MESH:D002318 cardiovascular abnormalities in Kawasaki disease
MESH:D003141 infectious diseases
MESH:D003550 cystic fibrosis|cystic fibrosis lung disease
MESH:D003643 mortality
MESH:D005368 filariasis
MESH:D006069 Neisseria meningitidis
MESH:D006509 hepatitis B
MESH:D006526 Hepatitis C virus infection
MESH:D007153 opsonic defect in immunodeficient|deficiency|immunodeficiency
MESH:D007239 malarial infection|infections|infection
MESH:D007896 leishmaniasis|Leishmaniasis
MESH:D007898 visceral leishmaniasis
MESH:D007918 leprosy
MESH:D008103 liver cirrhosis
MESH:D008107 liver disease
MESH:D008171 lung disease
MESH:D008180 systemic lupus erythematosus
MESH:D008288 malaria
MESH:D009203 postoperative myocardial infarction
MESH:D009336 necrotic
MESH:D009369 cancerous|tumor|melanoma cancer|lymphoma cancer
MESH:D010051 ovarian cancer
MESH:D010190 pancreatic cancer
MESH:D010272 parasitism|parasitic
MESH:D011008 pneumococcal pneumonia
MESH:D011014 pneumonia
MESH:D012131 respiratory failure
MESH:D012141 lung infections|respiratory tract infections
MESH:D012552 schistosomiasis
MESH:D012640 seizure
MESH:D013203 Staphylococcus aureus septicaemia
MESH:D013285 deficiency and concomitant immunodefects
MESH:D014352 trypanosomiasis
MESH:D014376 tuberculosis
MESH:D014397 pulmonary tuberculosis
MESH:D014848 vulvovaginal infections
MESH:D015179 colorectal cancer|colon cancer
MESH:D015658 immunodeficiency virus (HIV) infection|HIV/AIDS infected|HIV infection
MESH:D018352 respiratory syndrome coronavirus infection
MESH:D019694 chronic hepatitis B infection
MESH:D055370 lung injury
MESH:D064420 cytotoxicity
OMIM:120970 CRD
rs1009293589
A/G
GPI 2821 19:34399598 1
 29466428
Hemagglutinin-specific neutralization of subacute sclerosing panencephalitis viruses.
Muñoz-Alía MÁ, et. al. (2018); PLoS ONE; 2018; 13(2) 0192245. doi:10.1371/journal.pone.0192245
MESH:C000657245 SARS-CoV
MESH:C531768 panencefalitis esclerosante
MESH:C537366 Celma ML
MESH:D001102 viral infection|viral tropism
MESH:D001927 brain disease|brain diseases
MESH:D003643 death
MESH:D003967 diarrhea
MESH:D004194 damage to MeV-infected
MESH:D004660 virus encephalitis|encephalitis
MESH:D004679 encephalomyelitis
MESH:D005198 FBS
MESH:D005862 Autonoma de Madrid
MESH:D006526 Hepatitis C virus epitope
MESH:D006816 HD
MESH:D006938 retargeted VSV-FH
MESH:D007239 MeV infection
MESH:D009175 mycoplasma
MESH:D010031 otitis
MESH:D010051 hamster ovary
MESH:D011014 giant cell pneumonia|pneumonitis
MESH:D011535 PBS-T
MESH:D013344 panencephalitis|panencephalitis viruses
MESH:D015658 virus initiates infection
MESH:D018981 N-glycosylation efficiency
OMIM:615273 N-linked deglycosylation
rs10100465
G/A
LOC105375721 105375721 8:117614040 1
 33277640
Host genetics and infectious disease: new tools, insights and translational opportunities.
Kwok AJ, et. al. (2021); Nat Rev Genet; 2021 03 ; 22 (3) 137-153. doi:10.1038/s41576-020-00297-6
MESH:C000657245 covid-19|SARS-CoV-2 infection|Covid-19|COVID-19|COVID
MESH:C535338 total meningitis
MESH:C536020 agammaglobulinaemia|X-linked agammaglobulinaemia
MESH:C537005 C5-C9 deficiency C5, C6, C7
MESH:C537409 X-linked agammaglobulinemia
MESH:C537979 candidiasis CARD9
MESH:C563662 Invasive pneumococcal|invasive pneumococcal disease
MESH:C565169 pus Complement deficiencies C3 deficiency C3 AR Recurrent pyogenic infections
MESH:C565533 CYBA
MESH:C567115 primary immunodeficiency disorders Combined humoral
MESH:D000073296 non-infectious disease
MESH:D000081207 Primary immunodeficiencies|primary immunodeficiency disorders
MESH:D000163 AIDS
MESH:D000267 adhesion deficiency
MESH:D000544 AD
MESH:D000857 anosmia
MESH:D001102 virus disease|virus infection|viral infections
MESH:D001168 progressive polyarthritis|arthritis
MESH:D001170 infectious arthritis
MESH:D001228 Aspergillus infections
MESH:D001260 Ataxia telangiectasia|Ataxia-telangiectasia
MESH:D001327 autoimmunity|autoimmune diseases
MESH:D001424 Pyogenic bacterial infections|bacterial infections
MESH:D002177 candidiasis
MESH:D002180 X-linked Oral candidiasis
MESH:D002494 central nervous system infections
MESH:D003092 colitis
MESH:D003139 common cold
MESH:D003141 infectious disease|Infectious diseases|infectious diseases|multiple diseases|Infectious disease|infectious disease GWAS
MESH:D003371 cough
MESH:D003457 cryptosporidiosis Phagocytic cell defects Chronic granulomatous disease
MESH:D003643 mortality|death
MESH:D003715 dengue fever
MESH:D003881 Invasive dermatophytic
MESH:D003967 diarrhoea
MESH:D004342 allergy|hypersensitivity
MESH:D004660 encephalitis TLR3 AD Encephalitis|encephalitis
MESH:D004819 Epidermodysplasia verruciformis TMC6
MESH:D005334 fever
MESH:D005955 thalassaemia and glucose 6-phosphate dehydrogenase (G6PD) deficiency
MESH:D006105 chronic granulomatous disease|Chronic granulomatous disease|Granulomatous lesions
MESH:D006509 hepatitis B vaccination|HBV infection|hepatitis B|hepatitis B virus infection
MESH:D006525 viral hepatitis|Viral hepatitis
MESH:D006526 HCV infection|acute hepatitis C virus (HCV) infections|hepatitis C virus infection|hepatitis C virus
MESH:D007022 falciparum parasite to hijack red blood cell cytoskeletal remodelling
MESH:D007105 complex disease
MESH:D007153 Complement deficiencies|immunodeficiency disorders|TLR3 deficiencies|deficiency|complement deficiencies|immunodeficiencies|TLR3 deficiency|immunodeficiency
MESH:D007154 immunological abnormalities
MESH:D007239 skin infections|falciparum-infected|Infections|infection|rhinovirus infections|infections|infected|benign infection
MESH:D007249 inflammation
MESH:D007418 paralytic
MESH:D007710 Klebsiella
MESH:D007918 leprosy lesions|leprosy
MESH:D008232 X-lymphoproliferative disease
MESH:D008288 malaria|Malaria|hepatitis and malaria
MESH:D008586 pneumococcal meningitis
MESH:D008589 meningococcal disease|meningococcal infection|Meningococcal disease|meningococcal
MESH:D008661 inborn error|Inborn errors of type I|inborn errors|Inborn errors
MESH:D009181 fungal infections
MESH:D009336 tumour necrosis
MESH:D009361 invasive disease
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D010272 parasitic infection
MESH:D010518 periodontitis
MESH:D011014 pneumonia|pneumonitis
MESH:D011020 Pneumocystis jirovecii pneumonia
MESH:D011051 paralytic poliomyelitis
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 upper respiratory tract infections
MESH:D012214 Rheumatic heart disease|rheumatic heart disease
MESH:D012409 Rubella vaccination|rubella
MESH:D012480 nontyphoidal Salmonella bacteraemia|Salmonella bacteraemia
MESH:D012640 fitness
MESH:D012878 non-melanoma skin cancer
MESH:D013734 AR Cutaneous and mucosal lesions
MESH:D013746 tetanus
MESH:D014005 Deep dermatophytosis and inherited CARD9 deficiency
MESH:D014376 tuberculosis|Tuberculosis|tuberculosis hyper
MESH:D014390 meningeal tuberculosis
MESH:D014397 pulmonary tuberculosis
MESH:D014435 Non-typhoidalSalmonellainfection Non-typhoidal Salmonella bacteraemia|Typhoid Enteric fever
MESH:D014901 Nile neuroinvasive disease
MESH:D015212 inflammatory bowel disease|inflammatory bowel diseases
MESH:D015658 immunodeficiency virus (HIV) infection|Refs HIV infection|HIV infection|HIV-1 infection|HIV disease
MESH:D016393 hypogammaglobulinaemia or B cell lymphoma
MESH:D016470 bacteremia
MESH:D016511 Combined immunodeficiency|combined immunodeficiency|deficiencies Severe combined immunodeficiency
MESH:D016638 critical illness|critical disease
MESH:D016778 falciparum malaria
MESH:D016870 disseminated Neisseria infections
MESH:D018805 sepsis and pneumonia|sepsis
MESH:D018980 Williams
MESH:D019142 Ebola virus disease
MESH:D019595 Dengue fever Dengue shock syndrome|dengue hemorrhagic fever|dengue shock syndrome
MESH:D019694 Hepatitis B Chronic HBV infection
MESH:D019698 Hepatitis C Chronic HCV infection|chronic hepatitis C
MESH:D020031 Epstein-Barr virus infection
MESH:D020803 simplex virus encephalitis
MESH:D030342 inherited IRF9 deficiency|inherited MDA5 deficiency|genetic disorders|genetic defect|pneumococcal genetic variation|inherited TLR3 deficiency
MESH:D040181 X-linked Invasive disease
MESH:D045169 pneumonitis IRF7 X-linked Severe lung infection
MESH:D053306 hyper-IgM syndrome|hyper IgM syndromes|bronchiectasis Hyper-IgM syndrome AID
MESH:D053358 X-linked anhidrotic ectodermal dysplasia
MESH:D053360 hypohydrotic ectodermal dysplasia
MESH:D053632 IRAK-4 deficiency|bronchiectasis X-linked agammaglobulinaemia BTK X-linked|X-linked Haemophagocytosis
MESH:D056486 Hepatitis
MESH:D058495 haploinsufficiency|Haploinsufficient
rs1010288477
A/G
RTN2 6253 19:45488511 1
 33490695
Understanding the implications of SARS-CoV-2 re-infections on immune response milieu, laboratory tests and control measures against COVID-19.
Mustapha JO, et. al. (2021); Heliyon; 2021 Jan ; 7 (1) 05951. doi:10.1016/j.heliyon.2021.e05951
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|SARS-COv-2 infection|novel coronavirus disease|SARS-CoV-2 infections|CoV-2 infection|SARS-CoV-2 infected|SARS-CoV-2-infected|CoV-2 infection impairs dendritic cell|COVID-19|COVID
MESH:D000860 hypoxia
MESH:D001102 viral infection|viral infections
MESH:D001249 asthma
MESH:D002637 chest pain
MESH:D002908 chronic disease
MESH:D003371 dry cough
MESH:D003643 mortality|deaths|died
MESH:D003967 diarrhoea|diarrhea
MESH:D004244 dizziness
MESH:D004417 dyspnea
MESH:D005221 fatigue
MESH:D005334 pyrexia|fever
MESH:D006261 titters rise|headache
MESH:D007239 -infection|Infection|-infections|primary infection|infections|infection|infected
MESH:D008171 lung diseases
MESH:D008881 migraine
MESH:D009325 nausea
MESH:D010608 sore throat
MESH:D011014 pneumonia
MESH:D012131 respiratory disorder
MESH:D012220 rhinitis
MESH:D016638 critically ill
MESH:D018352 coronavirus infections|coronavirus infection
MESH:D018908 muscular weakness|muscle weakness
MESH:D052556 Nova Scotia
MESH:D055370 pulmonary injury
MESH:D063806 myalgia
rs1010930015
A/C
TBK1 29110 12:64460250 2
 32918943
The role of Host Genetics in susceptibility to severe viral infections in humans and INSIGHTS into host genetics of severe COVID-19: A systematic review.
Elhabyan A, et. al. (2020); Virus Res.; 2020 Sep 09 198163. doi:10.1016/j.virusres.2020.198163
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|SARS-CoV infection|SARS-CoV disease|COVID19|SARS CoV infectionORs|SARS CoV infection|COVID19 infection|Coronavirus Disease 2019|Coronavirus Disease-2019|COVID-19 disease|SARS-CoV infections|Covid-19|COVID-19|COVID
MESH:C535297 respiratory papillomatosis
MESH:C535750 IL-18BP deficiency
MESH:C536395 Virus-1(HSV-1) TLR3
MESH:D000073618 varicella zoster virus infections
MESH:D000402 airway hyperresponsiveness
MESH:D000860 hypoxemia
MESH:D001102 virus(IAV) infection|virus(VZV) infection|viral infections|viral disease|viral infection|virus infection|Virus Diseases|virus(VZV) infections
MESH:D001171 Still's disease
MESH:D001327 Autoimmune disease
MESH:D001766 complete TLR3 deficiency
MESH:D002318 cardiovascular disease
MESH:D003586 Disseminated cytomegalovirus infection
MESH:D003643 Mortality|Death|deaths|died|death
MESH:D003920 diabetes mellitus
MESH:D004660 virus encephalitis|Encephalitis|encephalitis
MESH:D005334 enterohemorrhagic fever|fever
MESH:D006480 hemorrhagic fever
MESH:D006509 hepatitis B virus infection
MESH:D006525 Hepatitis A virus(HAV|viral hepatitis|hepatitis A virus
MESH:D006973 hypertension
MESH:D007153 immune deficiency|UNC-93B deficiency|deficiency|immunological deficiencies|TLR3 deficiency|immunodeficiency|immunodeficiencies
MESH:D007239 rhinovirus infections|infections|infection|infected
MESH:D007249 allergic inflammation|Allergic Airway Inflammation|inflammation
MESH:D008661 Inborn Errors|Inborn Errors of RNA Lariat Metabolism|inborn errors|Inborn errors
MESH:D009102 organs injury
MESH:D009336 necrosis
MESH:D009369 malignancy
MESH:D010212 Papilloma virus infection
MESH:D011014 pneumonitis
MESH:D012030 error
MESH:D012120 acute respiratory syndrome|acute respiratory syndrome coronavirus infection
MESH:D012128 Acute respiratory distress syndrome|acute respiratory distress syndrome|ARDS
MESH:D012131 Respiratory Failure
MESH:D012140 respiratory disease
MESH:D012141 respiratory tract infections|respiratory infections
MESH:D012400 rotavirus infection
MESH:D013344 sclerosing panencephalitis|panencephalitis
MESH:D014376 tuberculosis
MESH:D015658 HIV infection|HIV|HIV-1 Infection
MESH:D017093 liver failure
MESH:D018186 Acute Pneumovirus Infection|pneumovirus
MESH:D018357 Respiratory Syncytial Virus Infection
MESH:D019595 Dengue hemorrhagic fever
MESH:D019636 Neurological deterioration
MESH:D020803 Herpes simplex encephalitis|TLR3 deficiency in herpes simplex encephalitis
MESH:D030342 inherited MDA5 deficiency|autosomal recessive and dominant TRIF deficiency|hereditary disorder of inflammasome|inherited TLR3 deficiency
MESH:D030361 Papillomavirus(HPV) infection N
MESH:D045169 Severe acute respiratory syndrome
OMIM:617237 49 T
 33219336
Host genetic susceptibility to viral infections: the role of type I interferon induction.
Bourdon M, et. al. (2020); Genes Immun; 2020 Nov 20 . doi:10.1038/s41435-020-00116-2
MESH:C000657245 SARS-CoV infection|SARS-CoV-2 infections|COVID-19|SARS-CoV-Infected
MESH:C535833 deficiencies increased
MESH:C536395 HSV-1 infection
MESH:C537849 ND CHIKV KO ND
MESH:D001102 viral diseases|Virus Disease|Viral Infection|viral infections|Virus Infection|Viral Diseases|viral infection|virus infection
MESH:D001766 complete TLR3 deficiency
MESH:D001768 myocarditic lesions
MESH:D001927 encephalopathy
MESH:D001988 bronchiolitis|IFNbeta Bronchiolitis|IFNbeta Bronchiolitis HRV
MESH:D003141 infectious diseases|Infectious disease
MESH:D003333 deficient human embryonic kidney
MESH:D003586 cytomegalovirus infection|cytomegalovirus (MCMV) infection
MESH:D003643 mortality|died
MESH:D003711 demyelinating disease
MESH:D004660 virus encephalitis|encephalitis
MESH:D004683 encephalomyelitis virus infection
MESH:D005355 fibrosis
MESH:D006327 KOs block
MESH:D006331 cardiac injury|cardiac anomalies
MESH:D006482 virus hemorrhagic fever
MESH:D006509 HBV hepatitis B virus|hepatitis B virus infection
MESH:D006526 hepatitis C virus
MESH:D007153 IFNbeta-deficient|Mavs deficiency|TLR3 deficiency
MESH:D007239 absence of infection|VV infection|IAV infection|infection|metapneumovirus infection|CHIKV infection|Infection|rhinovirus infections|infections|infected
MESH:D007249 inflammation|neuronal inflammation
MESH:D008545 melanoma
MESH:D008661 Inborn errors of type I
MESH:D009102 damage and organ failure
MESH:D009202 myocardial damage
MESH:D009369 tumor
MESH:D009410 neuronal damage
MESH:D009800 low neuroinflammation
MESH:D010850 encephalomyocarditis picornavirus
MESH:D011014 acute pneumonia|Pneumonia|pneumonia|pneumonitis
MESH:D012128 IFNlambda Acute respiratory distress syndrome
MESH:D012640 fitness
MESH:D012769 shock
MESH:D013344 sclerosing panencephalitis|panencephalitis
MESH:D014615 vaccinia infection|pulmonary vaccinia infection
MESH:D014766 viremia
MESH:D014901 WNV infection|WNV-infected|detrimental effect in WNV infection
MESH:D015499 Functional IRF3 deficiency
MESH:D015658 HIV infection|HIV-1 infection
MESH:D018357 respiratory syncytial virus infection
MESH:D018754 ventricular dysfunction
MESH:D019698 Chronic hepatitis C HRV
MESH:D020271 neurological disease
MESH:D020803 TLR3 deficiency in herpes simplex encephalitis|simplex encephalitis
MESH:D030342 autosomal recessive and dominant TRIF deficiency|inherited MDA5 deficiency|inherited TLR3 deficiency
MESH:D054243 VSV vesicular stomatitis virus
MESH:D056486 hepatitis or chronic hepatitis
rs10117466 Affx-33371257
G/T
FCN1 2219 9:134918015 1
 33193407
The Influence of the Lectin Pathway of Complement Activation on Infections of the Respiratory System.
Świerzko AS, et. al. (2020); Front Immunol; 2020 ; 11 585243. doi:10.3389/fimmu.2020.585243
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|COVID-19|SARS-CoV-1 infection|COVID
MESH:C563010 lung neutrophilia
MESH:C563602 complement-MBL|MBL deficiency|MBL insufficiency|MBL dysfunction|insufficiency of MBL
MESH:C563662 invasive pneumococcal disease
MESH:C564468 Low invasiveness of pneumococcal
MESH:D000071074 neonatal sepsis and pneumonia
MESH:D000079225 ischemic stress
MESH:D000309 insufficiency
MESH:D000783 microangiopathy
MESH:D001168 inflammatory arthritis
MESH:D001228 PTX3 deficiency and aspergillosis
MESH:D001778 coagulopathy
MESH:D001922 bilateral frontal cerebral abscesses
MESH:D003110 aeruginosa colonization
MESH:D003324 ischemic injury
MESH:D003550 cystic fibrosis bronchiectasis|cystic fibrosis
MESH:D003643 mortality|deaths
MESH:D004342 allergic|allergic diseases
MESH:D005355 fibrosis bronchiectasis
MESH:D006973 elevate
MESH:D007153 Immunodeficiency|deficiency|immunodeficiency
MESH:D007239 Infections|virulent Mycobacteria tuberculosis infection|infections|infected|infection
MESH:D007249 allergic inflammation|inflammation
MESH:D007511 ischaemic injury
MESH:D007674 renal epithelial injury
MESH:D007877 Legionnaires' disease|aeruginosa,Burkholderia cepacia,Legionella pneumophila
MESH:D008171 Lung diseases|lung disease
MESH:D008173 obstructive lung disease
MESH:D009102 organ failure|organ dysfunction|multiorgan failure
MESH:D009617 trachomatis,Nocardia farcinica
MESH:D009894 opportunistic Pasteurella pneumotropica
MESH:D010326 aeruginosa,Pasteurella pneumotropica|tuberculosis,Pasteurella pneumotropica
MESH:D011008 invasive pneumococcal infection|pneumococcal infection|pneumococcal|pneumococcal pneumonia
MESH:D011014 pneumonias|pneumonia
MESH:D011658 pulmonary fibrosis
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure
MESH:D012140 respiratory tract diseases|respiratory disease
MESH:D012141 deficiency and respiratory tract infection|respiratory tract infections|respiratory system infections|pulmonary infection|respiratory infections|Respiratory Infections|upper respiratory tract infections
MESH:D012852 sinus infections
MESH:D013927 thrombosis
MESH:D014376 tuberculosis
MESH:D014397 tuberculosis or neonatal pneumonia|pulmonary tuberculosis
MESH:D015470 acute myeloid leukaemia
MESH:D016638 critically ill
MESH:D017566 microvascular injury
MESH:D018352 respiratory syndrome coronavirus infection|coronavirus disease
MESH:D018357 respiratory syncytial virus (RSV) disease
MESH:D018805 sepsis
MESH:D019337 haematological malignancies
MESH:D019465 craniofacial abnormalities
MESH:D030342 Inherited deficiency
MESH:D055370 lung injury
MESH:D055744 pulmonary chronic necrotizing aspergillosis|invasive aspergillosis|chronic necrotizing pulmonary aspergillosis
MESH:D057049 thrombotic microangiopathy
OMIM:610906 allergic rhinitis/asthma
rs10120023
C/T
FCN1 2219 9:134918413 1
 33193407
The Influence of the Lectin Pathway of Complement Activation on Infections of the Respiratory System.
Świerzko AS, et. al. (2020); Front Immunol; 2020 ; 11 585243. doi:10.3389/fimmu.2020.585243
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|COVID-19|SARS-CoV-1 infection|COVID
MESH:C563010 lung neutrophilia
MESH:C563602 complement-MBL|MBL deficiency|MBL insufficiency|MBL dysfunction|insufficiency of MBL
MESH:C563662 invasive pneumococcal disease
MESH:C564468 Low invasiveness of pneumococcal
MESH:D000071074 neonatal sepsis and pneumonia
MESH:D000079225 ischemic stress
MESH:D000309 insufficiency
MESH:D000783 microangiopathy
MESH:D001168 inflammatory arthritis
MESH:D001228 PTX3 deficiency and aspergillosis
MESH:D001778 coagulopathy
MESH:D001922 bilateral frontal cerebral abscesses
MESH:D003110 aeruginosa colonization
MESH:D003324 ischemic injury
MESH:D003550 cystic fibrosis bronchiectasis|cystic fibrosis
MESH:D003643 mortality|deaths
MESH:D004342 allergic|allergic diseases
MESH:D005355 fibrosis bronchiectasis
MESH:D006973 elevate
MESH:D007153 Immunodeficiency|deficiency|immunodeficiency
MESH:D007239 Infections|virulent Mycobacteria tuberculosis infection|infections|infected|infection
MESH:D007249 allergic inflammation|inflammation
MESH:D007511 ischaemic injury
MESH:D007674 renal epithelial injury
MESH:D007877 Legionnaires' disease|aeruginosa,Burkholderia cepacia,Legionella pneumophila
MESH:D008171 Lung diseases|lung disease
MESH:D008173 obstructive lung disease
MESH:D009102 organ failure|organ dysfunction|multiorgan failure
MESH:D009617 trachomatis,Nocardia farcinica
MESH:D009894 opportunistic Pasteurella pneumotropica
MESH:D010326 aeruginosa,Pasteurella pneumotropica|tuberculosis,Pasteurella pneumotropica
MESH:D011008 invasive pneumococcal infection|pneumococcal infection|pneumococcal|pneumococcal pneumonia
MESH:D011014 pneumonias|pneumonia
MESH:D011658 pulmonary fibrosis
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure
MESH:D012140 respiratory tract diseases|respiratory disease
MESH:D012141 deficiency and respiratory tract infection|respiratory tract infections|respiratory system infections|pulmonary infection|respiratory infections|Respiratory Infections|upper respiratory tract infections
MESH:D012852 sinus infections
MESH:D013927 thrombosis
MESH:D014376 tuberculosis
MESH:D014397 tuberculosis or neonatal pneumonia|pulmonary tuberculosis
MESH:D015470 acute myeloid leukaemia
MESH:D016638 critically ill
MESH:D017566 microvascular injury
MESH:D018352 respiratory syndrome coronavirus infection|coronavirus disease
MESH:D018357 respiratory syncytial virus (RSV) disease
MESH:D018805 sepsis
MESH:D019337 haematological malignancies
MESH:D019465 craniofacial abnormalities
MESH:D030342 Inherited deficiency
MESH:D055370 lung injury
MESH:D055744 pulmonary chronic necrotizing aspergillosis|invasive aspergillosis|chronic necrotizing pulmonary aspergillosis
MESH:D057049 thrombotic microangiopathy
OMIM:610906 allergic rhinitis/asthma
rs1013716970
C/T
YOD1 55432 1:207049397 1
 27203180
Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.
Békés M, et. al. (2016); Mol. Cell; 2016 05 19; 62(4) 572-85. doi:10.1016/j.molcel.2016.04.016
MESH:C000657245 SARS-CoV-Infected|SARS-CoV
MESH:C536214 catalytic efficiency
MESH:C567070 Mycobacterial disease
MESH:D000309 insufficient
MESH:D001102 deubiquitination in viral infection|Viral OTU deubiquitinases
MESH:D007239 infection
MESH:D010051 viral ovarian tumor
MESH:D012131 respiratory syndrome|Respiratory Syndrome
MESH:D012640 goodness of fit
MESH:D015431 loss of catalytic efficiency
MESH:D018352 coronavirus infections|coronavirus|respiratory syndrome coronavirus|respiratory syndrome coronavirus papain|MERS|coronavirus infection|Middle East Respiratory Syndrome
MESH:D045169 SARS|SARS infection
OMIM:616126 inherited ISG15 deficiency
rs1013760982
G/A
A1CF 29974 10:50860838 1
 32780783
Global cataloguing of variations in untranslated regions of viral genome and prediction of key host RNA binding protein-microRNA interactions modulating genome stability in SARS-CoV-2.
Mukherjee M, et. al. (2020); PLoS ONE; 2020 ; 15 (8) 0237559. doi:10.1371/journal.pone.0237559
MESH:C000657245 SARS-Cov-2 infection|SARS-CoV-2 infected|Corona Virus disease-2019|COVID-19
MESH:D000077192 lung adenocarcinoma|Lung Adenocarcinoma
MESH:D000230 adenocarcinoma
MESH:D001102 viral infection|Viral infection
MESH:D001943 breast cancer
MESH:D002289 NSCLC
MESH:D002294 squamous cell carcinoma|lung squamous cell carcinoma
MESH:D003643 mortality
MESH:D005355 fibrosis|Fibrosis
MESH:D006323 arrest
MESH:D006525 Hepatitis Virus
MESH:D006528 hepatocellular carcinoma
MESH:D007239 infection|infected
MESH:D007249 inflammation|Inflammation
MESH:D008175 Lung Cancer|lung cancer|lung tumor|lung cancers|Lung Tumor
MESH:D009369 Cancer|cancer|tumor|pleural metastatic cancer
MESH:D010661 HPA
MESH:D011014 Lung inflammation|pulmonary inflammation|lung inflammation
MESH:D011658 pulmonary fibrosis
MESH:D012640 fits
MESH:D013274 gastric cancer
MESH:D017093 liver fibrogenesis
MESH:D019636 neurodegenerative disease
MESH:D055371 acute lung injury
MESH:D055752 small-cell lung cancer
rs1013910902
G/A,T
ACE2 59272 X:15534243 6
 32658335
The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity.
Ovsyannikova IG, et. al. (2020); Immunol. Rev.; 2020 07 ; 296 (1) 205-219. doi:10.1111/imr.12897
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|SARS-CoV infection|coronavirus disease 2019|SARS-CoV-2 respiratory failure|novel coronavirus pneumonia|2019 novel coronavirus diseases|CoV-2 infection|COVID-NET|COVID-19|COVID|SARS coronavirus tightly|Novel Coronavirus Pneumonia|COVID19 infection|2019 novel coronavirus-infected pneumonia|Covid-19
MESH:C563602 MBL deficiency
MESH:C563662 invasive pneumococcal disease
MESH:D000857 olfactory loss
MESH:D001102 viral infection|virus infection|viral infections
MESH:D002303 decrease diseases
MESH:D003141 infectious disease|infectious diseases
MESH:D003428 nosocomial infection
MESH:D003643 mortality|Mortality|deaths|death
MESH:D003920 diabetes
MESH:D004487 edema
MESH:D005334 fever
MESH:D005767 gastrointestinal (GI) distress
MESH:D006313 sensorineural impairment
MESH:D006525 hepatitis virus infection
MESH:D006526 HCV-infected
MESH:D006973 hypertension
MESH:D007239 Infection|infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 renal injury
MESH:D008171 lung damage
MESH:D008231 lymphopenia
MESH:D008586 pneumococcal meningitis
MESH:D008589 meningococcal disease|invasive meningococcal disease
MESH:D009205 myocarditis
MESH:D009765 obesity
MESH:D011008 pneumococcal infection|pneumococcal pneumonia
MESH:D011014 pneumonia|lung inflammation
MESH:D011471 prostate cancer
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 deficiency and respiratory tract infection|respiratory tract infection|respiratory infection|respiratory co-infections|respiratory tract infections|upper respiratory tract infections
MESH:D012409 rubella
MESH:D014376 tuberculosis
MESH:D015047 zoonotic
MESH:D015658 HIV-1 infection|HIV infections
MESH:D016534 increase or decrease disease
MESH:D018352 coronavirus infections|coronavirus disease|respiratory syndrome coronavirus infection|seasonal coronavirus infections|SARS coronavirus infection|MERS infections|middle east respiratory syndrome coronavirus attachment|coronavirus infection|MERS|Middle East respiratory syndrome-coronavirus infection
MESH:D029424 chronic obstructive pulmonary disease
MESH:D030342 Genetic deficiency
MESH:D045169 severe acute respiratory syndrome|SARS infection
MESH:D055370 lung injury|alveolar damage
MESH:D055371 acute lung failure
MESH:D056486 hepatitis coronavirus|hepatitis
 33243086
Assessing COVID-19 susceptibility through analysis of the genetic and epigenetic diversity of ACE2 mediated SARS-CoV-2 entry.
Ragia G, et. al. (2020); Pharmacogenomics; 2020 Nov 27 . doi:10.2217/pgs-2020-0092
MESH:C000657245 SARS-CoV-2 infection of breast or ovarian cancer|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-2 infections|coronavirus-2 infection|CoV-2 infection|SARS-CoV-2 infected|coronavirus disease 19|COVID-19
MESH:C537182 idiopathic ventricular fibrillation
MESH:C538007 Variations Variations
MESH:C538614 renal cell carcinoma
MESH:C566298 familial Alzheimer disease
MESH:D000544 Alzheimer's disease
MESH:D001145 heart arrhythmia|arrhythmias|congenital arrhythmia
MESH:D001523 psychiatric diseases
MESH:D001943 Breast Cancer|breast cancer|breast and prostate cancer
MESH:D002312 ventricular hypertrophy
MESH:D002318 cardiovascular disease|cardiovascular diseases
MESH:D002544 ischemic stroke
MESH:D003141 infectious diseases
MESH:D003324 coronary artery disease
MESH:D003643 Mortality|mortality|death
MESH:D003920 diabetes|diabetic
MESH:D003924 Type 2 diabetes|Type 2 Diabetes mellitus
MESH:D003928 atherosclerosis, diabetes kidney disease
MESH:D004194 multifactorial diseases
MESH:D006331 heart diseases
MESH:D006509 HBV infection|chronic HBV infection|hepatitis B virus infection
MESH:D006528 hepatocellular carcinoma
MESH:D006973 hypertension|hypertensive
MESH:D007153 deficiency
MESH:D007239 infected|infection
MESH:D007247 infertility
MESH:D007249 inflammation
MESH:D008133 long QT syndrome
MESH:D008171 pulmonary disease
MESH:D008175 lung cancer
MESH:D009203 myocardial infarction
MESH:D009369 Cancer|cancer|malignancies|tumors|epithelial cancers
MESH:D010024 osteoporosis
MESH:D010190 pancreatic cancer
MESH:D011014 pneumonia
MESH:D011471 longer prostate cancer|prostate tumor|primary prostate cancer|tumor growth in prostate cancer|prostate tumors|prostate cancer
MESH:D012128 acute respiratory distress syndrome
MESH:D012140 respiratory tract disease
MESH:D012141 lung infection
MESH:D017180 ventricular tachycardia
MESH:D017544 abdominal aortic aneurysm
MESH:D018352 coronavirus infections|MERS
MESH:D018805 sepsis
MESH:D020521 cerebral stroke
MESH:D024821 metabolic syndrome
MESH:D030342 neuroinflammatory disorders
MESH:D045169 Severe Acute Respiratory Syndrome
MESH:D050197 atherosclerotic rabbits|atherosclerosis
MESH:D050723 fracture
MESH:D055370 lung injury
 33542420
Dynamics of binding ability prediction between spike protein and human ACE2 reveals the adaptive strategy of SARS-CoV-2 in humans.
Xue X, et. al. (2021); Sci Rep; 2021 02 04 ; 11 (1) 3187. doi:10.1038/s41598-021-82938-2
MESH:C000657245 covid-19|SARS-CoV-2 infection|coronavirus disease-2019|COVID-19|COVID
MESH:D001102 viral infection
MESH:D003643 mortality|deaths
MESH:D007239 infected|infection
MESH:D011014 deadly pneumonia
MESH:D012140 respiratory disease
MESH:D012640 fitness
MESH:D015047 zoonotic|zoonotic coronavirus infection|zoonotic coronavirus
MESH:D018352 Coronavirus spectrum infections
 33590936
Genetic and epigenetic factors associated with increased severity of Covid-19.
Yildirim Z, et. al. (2021); Cell Biol Int; 2021 Feb 16 . doi:10.1002/cbin.11572
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|novel coronavirus pneumonia|2019 novel coronavirus diseases|SARS-CoV-2 infections|CoV-2 infection|2019-nCoV infection|SARS-CoV-2-infected|COVID-19|Coronavirus disease 2019|SARS-CoV-Infected|SARS-CoV-2 infected|SARS-Cov-2 infection|coronavirus disease-2019|Covid-19|SARS-CoV-2 Infection|coronavirus disease 2019 pneumonia|COVID19 lethality
MESH:C536170 DD
MESH:C566739 autosomal-dominant deficiencies
MESH:D000067390 cold
MESH:D000544 Alzheimer's disease
MESH:D000860 hypoxia
MESH:D001102 viral disease|viral infection|virus infection|viral infections
MESH:D001778 coagulation
MESH:D002318 cardiovascular disease
MESH:D003139 common cold
MESH:D003643 mortality|Mortality|Death|deaths|mortalities|death
MESH:D003920 diabetes|diabetes mellitus|diabetic
MESH:D003924 Type 2 diabetes
MESH:D005355 fibrosis
MESH:D006526 HCV infection|hepatitis C virus infection
MESH:D006566 B infection
MESH:D006973 hypertension
MESH:D007153 deficiency
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D007674 nondiabetic kidney disease|Collapsing glomerulopathy|Collapsing Glomerulopathy|glomerulopathy
MESH:D008180 lupus
MESH:D008661 Inborn errors of type I
MESH:D009102 multi-organ failure
MESH:D009103 familial multiple sclerosis
MESH:D009369 malignancy|cancer
MESH:D009422 neurological disorders
MESH:D011014 pneumonia|pneumonitis
MESH:D011471 prostate cancer
MESH:D012128 ARDS|acute respiratory distress syndrome|respiratory distress
MESH:D012131 respiratory failure
MESH:D012598 sclerosis
MESH:D012772 septic shock
MESH:D013927 thrombosis
MESH:D016638 critical illness|critical disease
MESH:D016893 Deficiency of IFNARs narrow
MESH:D018243 teratocarcinoma
MESH:D018352 coronavirus infections|respiratory syndrome coronavirus infection|human coronavirus infections
MESH:D018805 sepsis
MESH:D019698 chronic hepatitis C infection|chronic hepatitis C
MESH:D030342 inherited TLR3 deficiency
MESH:D045169 severe acute respiratory syndrome
MESH:D050197 atherosclerosis
MESH:D051436 chronic kidney disease
MESH:D054556 venous thromboembolism|Venous thromboembolism
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D058186 Acute kidney injury
MESH:D060085 immunodeficiency virus coinfected
 33607284
Variants in ACE2; potential influences on virus infection and COVID-19 severity.
Bakhshandeh B, et. al. (2021); Infect Genet Evol; 2021 Feb 16 104773. doi:10.1016/j.meegid.2021.104773
MESH:C000657245 covid-19|COVID-19 pneumonia|SARS-CoV-2 infection|SARS-CoV infected|coronavirus disease 2019|COVID-19 Disease|SARS-CoV-2 infections|novel coronavirus pneumonia|2019 novel coronavirus diseases|CoV-2 infection|Corona virus disease 2019|Coronavirus Disease 2019|COVID-19|COVID-2019|SARS coronavirus nonstructural|Coronavirus disease 2019|COVID-1 pneumonia|respiratory syndrome coronavirus 2 infection|SARS-CoV-2 Infection|SARS-CoV infections|Covid-19
MESH:D000860 hypoxemia HCoV|hypoxemia
MESH:D001102 virus infections|virus infection|viral infection
MESH:D001925 brain damage
MESH:D002318 cardiovascular disorders|cardiovascular disease|cardiovascular diseases
MESH:D003092 colitis
MESH:D003371 dry cough|cough
MESH:D003398 CRS
MESH:D003428 nosocomial infection
MESH:D003586 cytomegalovirus infection
MESH:D003643 mortality|deaths|death
MESH:D003920 diabetes|Diabetic Retinopathy|Diabetes
MESH:D003928 diabetic nephropathy
MESH:D004417 dyspnea
MESH:D004487 edema
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D005705 gall bladder
MESH:D006261 headache
MESH:D006331 heart dysfunction
MESH:D006333 heart failure
MESH:D006973 neurogenic hypertension|hypertension
MESH:D007029 hypothalamus
MESH:D007239 host infection|infections|infection|infected
MESH:D007249 inflammation|vascular inflammation
MESH:D007410 intestinal injury|intestinal damage
MESH:D007674 kidney diseases
MESH:D008171 lung damage
MESH:D009102 multi-organ failure
MESH:D009103 multiple sclerosis
MESH:D009127 rigidity
MESH:D009369 cancer
MESH:D010608 sore throat
MESH:D011014 acute pneumonia|pneumonia
MESH:D011658 Pulmonary fibrosis
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome|ARDS|ARDS inflammatory injury
MESH:D012131 lung failure
MESH:D012140 respiratory tract disease|respiratory diseases|respiratory disease
MESH:D012141 respiratory tract infections
MESH:D012220 rhinitis
MESH:D018352 coronavirus infections|MERS-CoV infected|MERS-coronavirus infection|coronavirus disease|respiratory syndrome coronavirus infection|coronavirus infection|Middle East respiratory syndrome-coronavirus infection
MESH:D045169 SARS fever|Severe acute respiratory syndrome
MESH:D050197 atherosclerosis
MESH:D051271 Emergence Disease Symptoms
MESH:D051436 chronic kidney disease
MESH:D055370 lung injury
MESH:D055371 acute lung failure
MESH:D063806 myalgia
 33868239
Genetics Insight for COVID-19 Susceptibility and Severity: A Review.
Fricke-Galindo I, et. al. (2021); Front Immunol; 2021 ; 12 622176. doi:10.3389/fimmu.2021.622176
MESH:C000657245 covid-19|COVID-19 pneumonia|SARS-CoV-2 infection|Covid|SARS-CoV-2 infected|CoV-2 Infection|Coronavirus Disease 2019|Coronavirus Disease 2019 Pneumonia|Coronavirus Disease 2019 Coagulopathy|Covid-19|SARS-CoV-2 Infection|coronavirus disease-2019|COVID-19
MESH:C536439 endotheliitis
MESH:C563010 neutrophilia
MESH:C566345 AFND
MESH:D000073296 noninfectious diseases
MESH:D000783 vascular disease
MESH:D001102 virus infection|viral infections
MESH:D001265 athletes
MESH:D001778 coagulopathies
MESH:D002318 cardiovascular system|cardiovascular disease
MESH:D002908 rhinovirus illness
MESH:D003141 infectious disease|Infectious diseases|infectious diseases
MESH:D003324 coronary heart disease
MESH:D003643 mortality|Mortality|Deaths|Death|deaths|death
MESH:D003920 diabetes mellitus|diabetes
MESH:D004211 disseminated intravascular coagulation|Disseminated Intravascular Coagulation|intravascular coagulation|DIC
MESH:D004417 dyspnea
MESH:D005334 fever
MESH:D006323 cardiac arrest
MESH:D006331 cardiac disease
MESH:D006333 heart failure
MESH:D006973 Hypertension|hypertension
MESH:D007022 hypotension
MESH:D007153 deficiencies of AT
MESH:D007239 infections|infection|infected
MESH:D007249 inflammation
MESH:D007676 end-stage renal disease
MESH:D007970 leukopenia
MESH:D008171 lung disease|lung damage
MESH:D008231 lymphopenia
MESH:D008288 malaria
MESH:D008661 Inborn errors of type I|inborn errors
MESH:D009102 multiorgan failure
MESH:D009202 Myocardial injury
MESH:D009203 myocardial infarction
MESH:D009205 myocarditis
MESH:D009369 cancer
MESH:D009461 chemosensory dysfunction|dysfunctional
MESH:D010031 otitis
MESH:D011014 pneumonia|lung inflammation
MESH:D012128 Acute Respiratory Distress Syndrome|ARDS
MESH:D012131 Respiratory Failure|respiratory failure
MESH:D012140 respiratory illness
MESH:D012141 respiratory infections|upper respiratory tract infection|upper respiratory tract infections
MESH:D012769 shock
MESH:D012772 septic shock and multiorgan failure|septic shock
MESH:D012893 olfactory disturbance
MESH:D013923 thromboembolism
MESH:D013927 thrombi
MESH:D015619 respiratory and systemic disease
MESH:D016638 critical illness|critically ill
MESH:D018352 coronavirus infections|coronavirus disease|MERS|Coronavirus disease|coronavirus tropism
MESH:D018805 sepsis
MESH:D020246 venous thrombosis|Venous thrombosis|deep vein thrombosis
MESH:D025861 coagulation abnormalities
MESH:D030342 neuroinflammatory disorders
MESH:D051436 chronic kidney disease
MESH:D054058 coronary syndrome
MESH:D054556 venous thromboembolism
MESH:D055370 chronic lung disease
MESH:D055954 endothelial cell injury
MESH:D057049 thrombotic microangiopathy|Thrombotic Microangiopathy
MESH:D058186 acute kidney injury
MESH:D060085 co-infection
rs10139525
A/G
ZBTB42 100128927 14:104818822 1
 26621837
Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations.
Zhang Y, et. al. (2016); Oncotarget; 2016 Jan 05; 7(1) 759-70. doi:10.18632/oncotarget.6397
MESH:C000657245 SARS-CoV infection
MESH:C562393 cutaneous melanoma
MESH:D000077274 nasopharyngeal carcinomas|nasopharyngeal carcinoma
MESH:D000230 adenocarcinoma
MESH:D001943 breast cancer
MESH:D002280 basal cell carcinoma
MESH:D002294 squamous cell carcinoma
MESH:D002583 cervical cancers
MESH:D002971 cleft lip palate
MESH:D003316 congenital corneal diseases
MESH:D005910 glioma
MESH:D006509 Hepatitis B virus (HBV) infection
MESH:D006528 hepatocellular carcinoma
MESH:D007105 complex disease
MESH:D008175 lung cancer|lung tumors|GWAS of lung cancer
MESH:D008545 melanoma
MESH:D009303
MESH:D009362 tumor-node-metastasis
MESH:D009369 Cancer|non-tumor|tumor|tumors|malignancy|cancer|cancers|Guangxi Cancer
MESH:D010051 serous ovarian|ovary cancer|ovarian tumor|serous ovarian cancer
MESH:D010190 pancreatic cancer
MESH:D010195 pancreatic
MESH:D011471 prostate cancers
MESH:D015179 colorectal cancer|colon cancer|colorectal cancers
MESH:D015451 chronic lymphocytic leukemia
MESH:D016889 endometrial cancer|endometrial cancers
MESH:D020022
MESH:D020031 Epstein-Barr virus infection
MESH:D052556 NPC carcinogenesis
MESH:D063646 carcinogenesis
rs1015164
A/C,G,T
CCRL2 9034 3:46410189 3
 32858232
Chemokine receptor gene polymorphisms and COVID-19: Could knowledge gained from HIV/AIDS be important?
Mehlotra RK, et. al. (2020); Infect. Genet. Evol.; 2020 Aug 26 ; 85 104512. doi:10.1016/j.meegid.2020.104512
MESH:C000657245 SARS-CoV-2 infection|Covid-19|COVID-19
MESH:D000163 AIDS
MESH:D000860 hypoxia
MESH:D001102 viral diseases|virus infection
MESH:D001172 rheumatoid arthritis
MESH:D001424 bacterial and parasitic infections
MESH:D001750 neurogenic pulmonary dysfunction
MESH:D002493 complications of the disease
MESH:D002609 CHS
MESH:D003141 infectious diseases
MESH:D003643 mortality|death
MESH:D006432 HH
MESH:D006467 hemophilia|Hemophilia growth
MESH:D006509 papillomavirus, Hepatitis B virus, Hepatitis C virus
MESH:D007153 immunodeficiency virus|immunologic deficiencies
MESH:D007239 infections|infection
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 pulmonary disease
MESH:D009181 fungal diseases
MESH:D009369 cancer|cancers
MESH:D009436 Ritchie MD
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure
MESH:D014766 viremia
MESH:D015658 HIV-1 disease|HIV infection|HIV|HIV-1 infection|HIV disease
MESH:D016506 HHD
MESH:D016638 critical disease
MESH:D017436 HHA
MESH:D018805 sepsis
MESH:D020078 neurogenic inflammation
MESH:D055370 lung injury
 33277640
Host genetics and infectious disease: new tools, insights and translational opportunities.
Kwok AJ, et. al. (2021); Nat Rev Genet; 2021 03 ; 22 (3) 137-153. doi:10.1038/s41576-020-00297-6
MESH:C000657245 covid-19|SARS-CoV-2 infection|Covid-19|COVID-19|COVID
MESH:C535338 total meningitis
MESH:C536020 agammaglobulinaemia|X-linked agammaglobulinaemia
MESH:C537005 C5-C9 deficiency C5, C6, C7
MESH:C537409 X-linked agammaglobulinemia
MESH:C537979 candidiasis CARD9
MESH:C563662 Invasive pneumococcal|invasive pneumococcal disease
MESH:C565169 pus Complement deficiencies C3 deficiency C3 AR Recurrent pyogenic infections
MESH:C565533 CYBA
MESH:C567115 primary immunodeficiency disorders Combined humoral
MESH:D000073296 non-infectious disease
MESH:D000081207 Primary immunodeficiencies|primary immunodeficiency disorders
MESH:D000163 AIDS
MESH:D000267 adhesion deficiency
MESH:D000544 AD
MESH:D000857 anosmia
MESH:D001102 virus disease|virus infection|viral infections
MESH:D001168 progressive polyarthritis|arthritis
MESH:D001170 infectious arthritis
MESH:D001228 Aspergillus infections
MESH:D001260 Ataxia telangiectasia|Ataxia-telangiectasia
MESH:D001327 autoimmunity|autoimmune diseases
MESH:D001424 Pyogenic bacterial infections|bacterial infections
MESH:D002177 candidiasis
MESH:D002180 X-linked Oral candidiasis
MESH:D002494 central nervous system infections
MESH:D003092 colitis
MESH:D003139 common cold
MESH:D003141 infectious disease|Infectious diseases|infectious diseases|multiple diseases|Infectious disease|infectious disease GWAS
MESH:D003371 cough
MESH:D003457 cryptosporidiosis Phagocytic cell defects Chronic granulomatous disease
MESH:D003643 mortality|death
MESH:D003715 dengue fever
MESH:D003881 Invasive dermatophytic
MESH:D003967 diarrhoea
MESH:D004342 allergy|hypersensitivity
MESH:D004660 encephalitis TLR3 AD Encephalitis|encephalitis
MESH:D004819 Epidermodysplasia verruciformis TMC6
MESH:D005334 fever
MESH:D005955 thalassaemia and glucose 6-phosphate dehydrogenase (G6PD) deficiency
MESH:D006105 chronic granulomatous disease|Chronic granulomatous disease|Granulomatous lesions
MESH:D006509 hepatitis B vaccination|HBV infection|hepatitis B|hepatitis B virus infection
MESH:D006525 viral hepatitis|Viral hepatitis
MESH:D006526 HCV infection|acute hepatitis C virus (HCV) infections|hepatitis C virus infection|hepatitis C virus
MESH:D007022 falciparum parasite to hijack red blood cell cytoskeletal remodelling
MESH:D007105 complex disease
MESH:D007153 Complement deficiencies|immunodeficiency disorders|TLR3 deficiencies|deficiency|complement deficiencies|immunodeficiencies|TLR3 deficiency|immunodeficiency
MESH:D007154 immunological abnormalities
MESH:D007239 skin infections|falciparum-infected|Infections|infection|rhinovirus infections|infections|infected|benign infection
MESH:D007249 inflammation
MESH:D007418 paralytic
MESH:D007710 Klebsiella
MESH:D007918 leprosy lesions|leprosy
MESH:D008232 X-lymphoproliferative disease
MESH:D008288 malaria|Malaria|hepatitis and malaria
MESH:D008586 pneumococcal meningitis
MESH:D008589 meningococcal disease|meningococcal infection|Meningococcal disease|meningococcal
MESH:D008661 inborn error|Inborn errors of type I|inborn errors|Inborn errors
MESH:D009181 fungal infections
MESH:D009336 tumour necrosis
MESH:D009361 invasive disease
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D010272 parasitic infection
MESH:D010518 periodontitis
MESH:D011014 pneumonia|pneumonitis
MESH:D011020 Pneumocystis jirovecii pneumonia
MESH:D011051 paralytic poliomyelitis
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 upper respiratory tract infections
MESH:D012214 Rheumatic heart disease|rheumatic heart disease
MESH:D012409 Rubella vaccination|rubella
MESH:D012480 nontyphoidal Salmonella bacteraemia|Salmonella bacteraemia
MESH:D012640 fitness
MESH:D012878 non-melanoma skin cancer
MESH:D013734 AR Cutaneous and mucosal lesions
MESH:D013746 tetanus
MESH:D014005 Deep dermatophytosis and inherited CARD9 deficiency
MESH:D014376 tuberculosis|Tuberculosis|tuberculosis hyper
MESH:D014390 meningeal tuberculosis
MESH:D014397 pulmonary tuberculosis
MESH:D014435 Non-typhoidalSalmonellainfection Non-typhoidal Salmonella bacteraemia|Typhoid Enteric fever
MESH:D014901 Nile neuroinvasive disease
MESH:D015212 inflammatory bowel disease|inflammatory bowel diseases
MESH:D015658 immunodeficiency virus (HIV) infection|Refs HIV infection|HIV infection|HIV-1 infection|HIV disease
MESH:D016393 hypogammaglobulinaemia or B cell lymphoma
MESH:D016470 bacteremia
MESH:D016511 Combined immunodeficiency|combined immunodeficiency|deficiencies Severe combined immunodeficiency
MESH:D016638 critical illness|critical disease
MESH:D016778 falciparum malaria
MESH:D016870 disseminated Neisseria infections
MESH:D018805 sepsis and pneumonia|sepsis
MESH:D018980 Williams
MESH:D019142 Ebola virus disease
MESH:D019595 Dengue fever Dengue shock syndrome|dengue hemorrhagic fever|dengue shock syndrome
MESH:D019694 Hepatitis B Chronic HBV infection
MESH:D019698 Hepatitis C Chronic HCV infection|chronic hepatitis C
MESH:D020031 Epstein-Barr virus infection
MESH:D020803 simplex virus encephalitis
MESH:D030342 inherited IRF9 deficiency|inherited MDA5 deficiency|genetic disorders|genetic defect|pneumococcal genetic variation|inherited TLR3 deficiency
MESH:D040181 X-linked Invasive disease
MESH:D045169 pneumonitis IRF7 X-linked Severe lung infection
MESH:D053306 hyper-IgM syndrome|hyper IgM syndromes|bronchiectasis Hyper-IgM syndrome AID
MESH:D053358 X-linked anhidrotic ectodermal dysplasia
MESH:D053360 hypohydrotic ectodermal dysplasia
MESH:D053632 IRAK-4 deficiency|bronchiectasis X-linked agammaglobulinaemia BTK X-linked|X-linked Haemophagocytosis
MESH:D056486 Hepatitis
MESH:D058495 haploinsufficiency|Haploinsufficient
 33558827
Chemokines and chemokine receptors during COVID-19 infection.
Khalil BA, et. al. (2021); Comput Struct Biotechnol J; 2021 ; 19 976-988. doi:10.1016/j.csbj.2021.01.034
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|SARS-CoV infection|SARS-CoV infected|coronavirus disease 2019|SARS-CoV-infected|SARS-CoV-2 infected|SARS-CoV infected DCs|CoV-2 infection|COVID-19
MESH:C563010 neutrophilia
MESH:D000163 AIDS
MESH:D001102 viral infection|virus infection|viral infections|virally-infected
MESH:D001228 aspergillosis
MESH:D001855 bone marrow gives rise
MESH:D001989 bronchiolitis obliterans syndrome
MESH:D002276 goblet cell hyperplasia
MESH:D003371 cough
MESH:D003398 CRS
MESH:D003550 cystic fibrosis lung disease
MESH:D003586 cytomegalovirus infections|cytomegalovirus infection|cytomegalovirus (MCMV) infection
MESH:D003643 mortality|death
MESH:D004342 allergic
MESH:D004660 virus encephalitis
MESH:D005221 fatigue
MESH:D006099 pulmonary granuloma
MESH:D006470 intra-alveolar hemorrhage
MESH:D006509 hepatitis B and HIV infections|hepatitis B
MESH:D006528 hepatocellular carcinoma
MESH:D007239 Infection|rhinovirus infection|infection|infected
MESH:D007249 hyperactive inflammation|inflammation
MESH:D008107 liver disease
MESH:D008171 pulmonary immunopathology|lung diseases
MESH:D008173 obstructive pulmonary disease
MESH:D008223 leukemias and lymphomas
MESH:D008231 lymphopenia|Lymphopenia
MESH:D009103 multiple sclerosis
MESH:D009181 fungal disease
MESH:D009207 MJ
MESH:D009369 cancer|tumor|neoplasia|tumour
MESH:D011014 pneumonia|pulmonary inflammation|lung inflammation
MESH:D011658 pulmonary fibrosis
MESH:D012120 acute respiratory disease syndrome
MESH:D012128 Acute respiratory distress syndrome|acute respiratory distress syndrom|ARDS|acute respiratory distress syndrome|adult respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory death
MESH:D012141 respiratory infection|respiratory virus infections reduced pulmonary immunopathology|respiratory tract infections|pulmonary infection
MESH:D012818 respiratory symptoms
MESH:D014766 viremia
MESH:D015427 reperfusion injury|kidney ischemia reperfusion injury
MESH:D015658 HIV-infected|HIV infection|HIV-1 infection|HIV-1-infected|human immunodeficiency virus infection
MESH:D016638 critically ill
MESH:D016920 bacterial pneumonia
MESH:D017093 liver toxicityUpregulated
MESH:D018184 parainfluenza virus Infection
MESH:D018352 coronavirus infections|MERS-CoV infection|respiratory syndrome coronavirus infection|SARS-coronavirus infection|SARS coronavirus-infected|SARS coronavirus infection|respiratory syndrome coronavirus-infected|CoV infection|MERS-CoV infected|SARS-coronavirus-infected|MERS|human coronavirus infections|CoV-infected
MESH:D018357 respiratory syncytial virus-infected|respiratory syncytial virus infection
MESH:D019698 chronic hepatitis C infection|chronic hepatitis C
MESH:D029424 chronic obstructive pulmonary disease|COPD
MESH:D045169 severe acute respiratory syndrome coronavirus-infected|severe acute respiratory syndrome|Severe acute respiratory syndrome
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D056486 liver toxicity|hepatitis and HIV|liver and kidney injuries
MESH:D058186 acute renal failure
rs10154090 Affx-18057221
T/A
TMPRSS2 7113 21:41491796 1
 33101356
Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene Variants.
Iyer GR, et. al. (2020); Front Genet; 2020 ; 11 861. doi:10.3389/fgene.2020.00861
MESH:C000657245 covid-19|SARS-CoV-2 infection|COVID19|novel coronavirus disease|COVID-19
MESH:C536174 panbronchiolitis
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001249 asthma
MESH:D001988 bronchiolitis
MESH:D002318 cardiovascular disorders
MESH:D003092 colitis
MESH:D003141 infectious diseases
MESH:D003229 conjunctival infection
MESH:D003586 cytomegalovirus disease
MESH:D003643 mortality
MESH:D003715 dengue fever
MESH:D003920 diabetes|diabetes mellitus
MESH:D004342 allergic
MESH:D004417 shortness of breath
MESH:D004675 tick-borne encephalitis
MESH:D005355 fibrosis
MESH:D006333 chronic heart failure
MESH:D006965 hyperplasia
MESH:D007239 establishing infections|infections|infection|infected
MESH:D007249 inflammation
MESH:D008171 lung abnormalities|lung disease|lung diseases
MESH:D009080 Kawasaki disease
MESH:D011009 pneumoconiosis
MESH:D011471 prostate cancer
MESH:D011658 pulmonary fibrosis
MESH:D012128 respiratory distress
MESH:D012131 respiratory disorders|respiratory failure
MESH:D012140 respiratory illness
MESH:D012141 upper respiratory infection
MESH:D014376 tuberculosis
MESH:D014397 pulmonary tuberculosis
MESH:D015179 colorectal cancer
MESH:D015658 HIV-1 infection
MESH:D018352 coronavirus disease|MERS|Middle East Respiratory Syndrome
MESH:D018980 Williams
MESH:D020521 stroke
MESH:D030342 genetic disease
MESH:D054243 vesicular stomatitis virus infection
MESH:D054990 idiopathic pulmonary fibrosis|Idiopathic pulmonary fibrosis
MESH:D055371 acute lung injury
MESH:D055744 invasive pulmonary aspergillosis infection|invasive pulmonary Aspergillosis infection
MESH:D058625 end-stage lung disease
MESH:D064420 memory Cytotoxic T
rs1015482477
T/C
WASF2 10163 1:27416097 1
 33127862
Molecular Architecture of Early Dissemination and Massive Second Wave of the SARS-CoV-2 Virus in a Major Metropolitan Area.
Long SW, et. al. (2020); mBio; 2020 Oct 30 ; 11 (6) . doi:10.1128/mBio.02707-20
MESH:C000657245 SARS-CoV-2 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|coronavirus-covid-19|CoV-2 infection|Covid-19|SARS-CoV-2 fitness|COVID-19
MESH:D000080345 XL
MESH:D001102 virus infection
MESH:D003141 Infectious Diseases
MESH:D003643 mortality|Mortality|deaths
MESH:D004342 Allergy
MESH:D005221 fatigue
MESH:D007239 infections|infected|infection
MESH:D007319 inability
MESH:D007710 Klebsiella pneumoniae
MESH:D011014 pneumonia
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 respiratory infections
MESH:D012640 fitness|virus fitness
MESH:D018352 CoV infection
rs1016409802 Affx-446876144
T/C
ACE2 59272 X:15573394 5
 32423095
The Expression and Polymorphism of Entry Machinery for COVID-19 in Human: Juxtaposing Population Groups, Gender, and Different Tissues.
Darbani B, et. al. (2020); Int J Environ Res Public Health; 2020 05 14 ; 17 (10) . doi:10.3390/ijerph17103433
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV infection|SARS-CoV-infected|2019 novel coronavirus diseases|CoV-2 infection|SARS-CoV-2 infected|Coronavirus Disease 2019|2019 novel coronavirus-infected pneumonia|COVID-19
MESH:D001102 viral disease
MESH:D002318 cardiovascular disease
MESH:D003324 coronary heart disease
MESH:D003643 mortality|death
MESH:D003920 diabetes|diabetes mellitus
MESH:D006973 hypertension
MESH:D007239 infection
MESH:D009203 myocardial infarction
MESH:D011014 pneumonia
MESH:D012131 respiratory failure
MESH:D012640 fitness
MESH:D018352 respiratory syndrome coronavirus entry
MESH:D045169 Severe acute respiratory syndrome
 32912711
ACE2", "polymorphism", "DPP4" and "telemedicine" was conducted on Pubmed and EMBASE till 7th August 2020. RESULT: Possible polymorphisms in ACE2 gene can play a role in influencing the virus entry in host body. Telemedicine can bring a new revolution for medical sector. CONCLUSION: COVID-19 severity is more heinous among diabetic population. So far, the in-silico studies involving human ACE2-viral Spike (S) interaction showed inconsistent predictions regarding some SNPs. But without actual in-vivo studies, a holistic understanding can't be established.">COVID-19 and diabetes; Possible role of polymorphism and rise of telemedicine.
Sayed S, et. al. (2021); Prim Care Diabetes; 2021 02 ; 15 (1) 4-9. doi:10.1016/j.pcd.2020.08.018
MESH:C000657245 covid-19|SARS-CoV-2 infection|coronavirus disease 2019|COVID19|corona virus disease 2019|CoV-2 infection|2019-nCoV infection|Coronavirus Disease 2019|2019 novel coronavirus pneumonia|COVID-19|NCP|SARS-CoV-2 pneumonia|SARS-Cov-2 infection|Covid-19|SARS-CoV-2 Infection|coronavirus-2019
MESH:C536439 endothelial dysfunction
MESH:D001102 Viral infections|viral infection
MESH:D001327 autoimmune insulitis
MESH:D002318 cardiovascular disease
MESH:D002908 chronic disease
MESH:D003324 coronary heart disease
MESH:D003371 cough
MESH:D003643 mortality|Mortality|deaths|death
MESH:D003919 diabetes insipidus
MESH:D003920 Abbott Diabetes|diabetes|diabetes mellitus|diabetic|Diabetic|Diabetes|Diabetes Federation Diabetes Atlas
MESH:D003922 type 1 diabetes|autoimmune diabetes|Type 1 Diabetes|diabetes autoimmunity
MESH:D003924 type 2 diabetes|Type 2 diabetes|type 2 diabetes mellitus
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D006261 headache
MESH:D006943 hyperglycemia
MESH:D006963 polyphagia and polydipsia
MESH:D006973 hypertension
MESH:D007239 infected|infection
MESH:D007249 hyper-inflammation|Inflammation
MESH:D007333 insulin deficiency|insulin secretion
MESH:D008231 lymphocytopenia
MESH:D008659 metabolic disorder
MESH:D009102 multi-organ failure
MESH:D009223 DM
MESH:D009336 necrosis
MESH:D009369 cancer
MESH:D010182 Pancreatic Damage
MESH:D011507 proteinuria
MESH:D012140 respiratory disease
MESH:D012141 respiratory tract infection|Respiratory infections
MESH:D014947 injuries
MESH:D015658 HIV infection|HIV-1 infection
MESH:D016638 critically ill
MESH:D016883 Diabetic Ketoacidosis
MESH:D018352 MERS-CoV infection|coronavirus infection
MESH:D050171 dyslipidemia
 33205496
Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment.
Al-Eitan LN, et. al. (2020); Rev Med Virol; 2020 Nov 17 2194. doi:10.1002/rmv.2194
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|Coronavirus disease 2019|novel coronavirus pneumonia|SARS-CoV-2 infections|CoV-2 infection|coronavirus disease-2019|Covid-19|COVID-19|Covid 19 pneumonia
MESH:D000072658 NSTEMI
MESH:D000740 anemia|anaemia
MESH:D000743 Haemolytic anaemia|hemolytic anemia
MESH:D001102 viral diseases|viral infection
MESH:D001172 rheumatoid arthritis
MESH:D001327 autoimmune disease|autoimmune diseases
MESH:D001778 coagulopathy|coagulation
MESH:D002318 cardiovascular disease|cardiovascular diseases
MESH:D002544 ischemic stroke
MESH:D003371 coughing
MESH:D003643 mortality|deaths|mortalities|death
MESH:D003920 diabetes|diabetic
MESH:D003924 type-2 diabetes mellitus
MESH:D005334 fever
MESH:D006461 haemolysis
MESH:D006509 hepatitis B virus|hepatitis B HBeAg|hepatitis B|hepatitis B virus infection
MESH:D006526 thrombocytopenia in hepatitis C|HCV-infected|HCV
MESH:D006973 hypertension|hypertensive
MESH:D007153 immunodeficiency virus
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D008175 lung tumor
MESH:D008179 chronic discoid lupus erythematosus
MESH:D008180 systemic lupus erythematosus
MESH:D008288 malaria|malaria to autoimmunity
MESH:D009203 myocardial infarction
MESH:D009336 tumour necrosis
MESH:D010300 PD
MESH:D011014 pneumonia|lung inflammation
MESH:D012128 acute respiratory distress syndrome
MESH:D012131 lung failure
MESH:D012140 respiratory disease
MESH:D012141 lung infections|respiratory infections
MESH:D012216 rheumatic
MESH:D013921 thrombocytopenia
MESH:D015047 zoonotic
MESH:D015658 HIV-infected|HIV
MESH:D017093 decreased hepatic midazolam metabolism
MESH:D018352 coronavirus infection|Middle East Respiratory Syndrome|middle east respiratory syndrome|Middle East respiratory syndrome
MESH:D019698 chronic hepatitis C
MESH:D024821 metabolic syndrome
MESH:D052439 lipid toxicity
MESH:D054058 acute coronary syndrome|coronary syndrome
MESH:D055370 lung injury
MESH:D058186 acute renal failure
MESH:D063806 muscle pain
MESH:D064420 toxicity
 33243086
Assessing COVID-19 susceptibility through analysis of the genetic and epigenetic diversity of ACE2 mediated SARS-CoV-2 entry.
Ragia G, et. al. (2020); Pharmacogenomics; 2020 Nov 27 . doi:10.2217/pgs-2020-0092
MESH:C000657245 SARS-CoV-2 infection of breast or ovarian cancer|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-2 infections|coronavirus-2 infection|CoV-2 infection|SARS-CoV-2 infected|coronavirus disease 19|COVID-19
MESH:C537182 idiopathic ventricular fibrillation
MESH:C538007 Variations Variations
MESH:C538614 renal cell carcinoma
MESH:C566298 familial Alzheimer disease
MESH:D000544 Alzheimer's disease
MESH:D001145 heart arrhythmia|arrhythmias|congenital arrhythmia
MESH:D001523 psychiatric diseases
MESH:D001943 Breast Cancer|breast cancer|breast and prostate cancer
MESH:D002312 ventricular hypertrophy
MESH:D002318 cardiovascular disease|cardiovascular diseases
MESH:D002544 ischemic stroke
MESH:D003141 infectious diseases
MESH:D003324 coronary artery disease
MESH:D003643 Mortality|mortality|death
MESH:D003920 diabetes|diabetic
MESH:D003924 Type 2 diabetes|Type 2 Diabetes mellitus
MESH:D003928 atherosclerosis, diabetes kidney disease
MESH:D004194 multifactorial diseases
MESH:D006331 heart diseases
MESH:D006509 HBV infection|chronic HBV infection|hepatitis B virus infection
MESH:D006528 hepatocellular carcinoma
MESH:D006973 hypertension|hypertensive
MESH:D007153 deficiency
MESH:D007239 infected|infection
MESH:D007247 infertility
MESH:D007249 inflammation
MESH:D008133 long QT syndrome
MESH:D008171 pulmonary disease
MESH:D008175 lung cancer
MESH:D009203 myocardial infarction
MESH:D009369 Cancer|cancer|malignancies|tumors|epithelial cancers
MESH:D010024 osteoporosis
MESH:D010190 pancreatic cancer
MESH:D011014 pneumonia
MESH:D011471 longer prostate cancer|prostate tumor|primary prostate cancer|tumor growth in prostate cancer|prostate tumors|prostate cancer
MESH:D012128 acute respiratory distress syndrome
MESH:D012140 respiratory tract disease
MESH:D012141 lung infection
MESH:D017180 ventricular tachycardia
MESH:D017544 abdominal aortic aneurysm
MESH:D018352 coronavirus infections|MERS
MESH:D018805 sepsis
MESH:D020521 cerebral stroke
MESH:D024821 metabolic syndrome
MESH:D030342 neuroinflammatory disorders
MESH:D045169 Severe Acute Respiratory Syndrome
MESH:D050197 atherosclerotic rabbits|atherosclerosis
MESH:D050723 fracture
MESH:D055370 lung injury
 33590936
Genetic and epigenetic factors associated with increased severity of Covid-19.
Yildirim Z, et. al. (2021); Cell Biol Int; 2021 Feb 16 . doi:10.1002/cbin.11572
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|novel coronavirus pneumonia|2019 novel coronavirus diseases|SARS-CoV-2 infections|CoV-2 infection|2019-nCoV infection|SARS-CoV-2-infected|COVID-19|Coronavirus disease 2019|SARS-CoV-Infected|SARS-CoV-2 infected|SARS-Cov-2 infection|coronavirus disease-2019|Covid-19|SARS-CoV-2 Infection|coronavirus disease 2019 pneumonia|COVID19 lethality
MESH:C536170 DD
MESH:C566739 autosomal-dominant deficiencies
MESH:D000067390 cold
MESH:D000544 Alzheimer's disease
MESH:D000860 hypoxia
MESH:D001102 viral disease|viral infection|virus infection|viral infections
MESH:D001778 coagulation
MESH:D002318 cardiovascular disease
MESH:D003139 common cold
MESH:D003643 mortality|Mortality|Death|deaths|mortalities|death
MESH:D003920 diabetes|diabetes mellitus|diabetic
MESH:D003924 Type 2 diabetes
MESH:D005355 fibrosis
MESH:D006526 HCV infection|hepatitis C virus infection
MESH:D006566 B infection
MESH:D006973 hypertension
MESH:D007153 deficiency
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D007674 nondiabetic kidney disease|Collapsing glomerulopathy|Collapsing Glomerulopathy|glomerulopathy
MESH:D008180 lupus
MESH:D008661 Inborn errors of type I
MESH:D009102 multi-organ failure
MESH:D009103 familial multiple sclerosis
MESH:D009369 malignancy|cancer
MESH:D009422 neurological disorders
MESH:D011014 pneumonia|pneumonitis
MESH:D011471 prostate cancer
MESH:D012128 ARDS|acute respiratory distress syndrome|respiratory distress
MESH:D012131 respiratory failure
MESH:D012598 sclerosis
MESH:D012772 septic shock
MESH:D013927 thrombosis
MESH:D016638 critical illness|critical disease
MESH:D016893 Deficiency of IFNARs narrow
MESH:D018243 teratocarcinoma
MESH:D018352 coronavirus infections|respiratory syndrome coronavirus infection|human coronavirus infections
MESH:D018805 sepsis
MESH:D019698 chronic hepatitis C infection|chronic hepatitis C
MESH:D030342 inherited TLR3 deficiency
MESH:D045169 severe acute respiratory syndrome
MESH:D050197 atherosclerosis
MESH:D051436 chronic kidney disease
MESH:D054556 venous thromboembolism|Venous thromboembolism
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D058186 Acute kidney injury
MESH:D060085 immunodeficiency virus coinfected
rs1016773134
G/A
TMPRSS2 7113 21:41494457 3
 31013314
Consensus and variations in cell line specificity among human metapneumovirus strains.
Nao N, et. al. (2019); PLoS One. 2019 Apr 23;14(4):e0215822. doi: 10.1371/journal.pone.0215822.
MESH:C000657245 SARS-CoV infection
MESH:D000077192 lung adenocarcinoma A549
MESH:D001102 viral disease
MESH:D003920 diabetes
MESH:D006323 cardiopulmonary diseases
MESH:D006816 HD
MESH:D007239 HMPV infection|HMPV infections|VSV)-infected or mock-infected A549|VSV-infected|metapneumovirus infections|VSV-infected A549|metapneumovirus infection
MESH:D008545 melanoma|melanoma MNT-1|malignant melanoma
MESH:D011014 pneumonia
MESH:D012131 respiratory infection|respiratory illness|respiratory syndrome|respiratory infections
MESH:D012140 respiratory tract disease
MESH:D012141 respiratory-tract infections
MESH:D015658 virus infections|Tulane virus infection
MESH:D017180 VT
MESH:D018184 parainfluenza viruses
MESH:D018186 pneumovirus
MESH:D018352 coronavirus
MESH:D030342 genetic defect
MESH:D045169 SARS
MESH:D063129 VSV-infected parental
 32674988
Human Organs-on-Chips for Virology.
Tang H, et. al. (2020); Trends Microbiol.; 2020 Jul 13 . doi:10.1016/j.tim.2020.06.005
MESH:C000657245 SARS-CoV-2 infected|SARS-CoV-2 infection|coronavirus disease 2019|COVID19|COVID-19
MESH:C557675 trachea
MESH:D000544 Alzheimer's disease
MESH:D001102 viral disease|virus disease|viral diseases|Viral Diseases|viral infection|virus infection|viral infections
MESH:D001161 arteriosclerosis
MESH:D001249 asthma
MESH:D001855 bone marrow toxicities
MESH:D001943 Melatonin decreases breast cancer metastasis
MESH:D003141 infectious diseases
MESH:D003643 mortality
MESH:D003920 diabetic
MESH:D003928 diabetic nephropathy
MESH:D005234 fatty liver|steatohepatitis
MESH:D005334 Fever|fever
MESH:D005355 cirrhosis
MESH:D005759 gastroenteritis
MESH:D006504 Liver Sinusoid Chip for HBV Infection
MESH:D006509 HBV infection|Hepatitis B|hepatitis B|hepatitis B virus infection
MESH:D006525 viral hepatitis
MESH:D006528 hepatocellular carcinoma
MESH:D007239 Infection|infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 renal abnormalities|kidney dysfunctions|renal dysfunctions|kidney disease
MESH:D008103 liver fibrosis
MESH:D008107 liver diseases
MESH:D008113 Viral hepatitis and liver cancer
MESH:D008659 metabolic dysfunction
MESH:D009102 vascular leakage and multiorgan failure
MESH:D009336 necrotic
MESH:D009369 cancer|Modelling cancer
MESH:D009422 neurological systems and disorders
MESH:D010272 parasitic
MESH:D010523 peripheral nervous system (PNS) neuronal component|CNS-PNS junction
MESH:D011014 lung inflammation
MESH:D011654 pulmonary edema
MESH:D012140 respiratory diseases|respiratory disease
MESH:D012141 respiratory infection
MESH:D012771 Ebola hemorrhagic shock syndrome
MESH:D013927 intravascular thrombosis
MESH:D014947 injury
MESH:D015179 Colorectal tumor
MESH:D017093 liver infection
MESH:D019142 Ebola disease|Ebola haemorrhagic fever
MESH:D020141 vascular impairment
MESH:D020271 neurological disease|neurologic diseases
MESH:D028361 mitochondrial dysfunction
MESH:D030342 genetic disease
MESH:D055370 lung injury
MESH:D057772 vascular cell injury
MESH:D058625 chronic liver infection
MESH:D060085 coinfection|secondary infections|Co-infection
MESH:D064420 toxicity|drug toxicities
 33358483
Evaluation of variant frequency in SARS-CoV-2 infection-related genes utilizing lung cancer genomic database.
Shibata Y, et. al. (2020); Lung Cancer; 2020 Dec 23 . doi:10.1016/j.lungcan.2020.12.016
MESH:C000657245 CoV-2 infection|SARS-CoV-2 infection|COVID-19|coronavirus-2019
MESH:D001281 AF
MESH:D003643 deaths
MESH:D008175 Lung Cancer|lung cancer
MESH:D011014 pneumonia
rs1016777825 Affx-446875995
C/G
ACE2 59272 X:15571784 8
 32249956
Structural variations in human ACE2 may influence its binding with SARS-CoV-2 spike protein.
Hussain M, et. al. (2020); J. Med. Virol.; 2020 Apr 06 . doi:10.1002/jmv.25832
MESH:C000657245 CoV-2 infection|SARS-CoV-2 infection|SARS-CoV infection|COVID-19|SARS coronavirus S
MESH:D001102 viral infection
MESH:D002318 cardiovascular disorders
MESH:D003643 mortality|deaths
MESH:D003920 diabetes
MESH:D003924 type 2 diabetes mellitus
MESH:D006973 hypertension
MESH:D007239 infection|infected
MESH:D012120 acute respiratory syndrome
MESH:D012164 retinopathy
MESH:D015658 HIV infection|HIV-1 infection
MESH:D018352 MERS-CoV infected|coronavirus infection
MESH:D030342 genetic disorder
MESH:D045169 severe acute respiratory syndrome
 32538738
Molecular simulation of SARS-CoV-2 spike protein binding to pangolin ACE2 or human ACE2 natural variants reveals altered susceptibility to infection.
Wang J, et. al. (2020); J Gen Virol; 2020 09 ; 101 (9) 921-924. doi:10.1099/jgv.0.001452
MESH:C000657245 CoV-2 infection|covid-19|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-2 infected HeLa|Coronavirus disease 2019|COVID-19
MESH:D001281 AF
MESH:D003643 deaths
MESH:D006973 hypertension
MESH:D007239 infections|infection
MESH:D009190 MDS
MESH:D011014 pneumonia
MESH:D018352 coronavirus infection|Coronavirus disease
MESH:D051436 chronic kidney disease
 32858233
A survey of genetic variants in SARS-CoV-2 interacting domains of ACE2, TMPRSS2 and TLR3/7/8 across populations.
Lee IH, et. al. (2020); Infect Genet Evol; 2020 11 ; 85 104507. doi:10.1016/j.meegid.2020.104507
MESH:C000657245 SARS-CoV-2 infection|Coronavirus disease 2019|novel coronavirus pneumonia|Covid-19|COVID-19
MESH:C566236 RS ID Impact AA Change gnomAD
MESH:D001102 viral infection|virus infection
MESH:D001281 AF
MESH:D003643 mortality|deaths
MESH:D007239 infected
MESH:D011014 pneumonia
MESH:D011471 prostate and prostate cancer epithelia
MESH:D012131 respiratory failure
MESH:D012141 upper respiratory tract infection
 32916377
Silico analysis of interaction between full-length SARS-CoV2 S protein with human Ace2 receptor: Modelling, docking, MD simulation.
Rui L, et. al. (2020); Biophys. Chem.; 2020 Sep 03 ; 267 106472. doi:10.1016/j.bpc.2020.106472
MESH:C000657245 SARS-CoV-2 infection|COVID-19
 32938937
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.
Sorokina M, et. al. (2020); Sci Data; 2020 09 16 ; 7 (1) 309. doi:10.1038/s41597-020-00652-6
MESH:C000657245 SARS-CoV-2 infection|Novel Coronavirus-Infected Pneumonia|COVID-19
MESH:C536528 vdW-van der
MESH:C564120 000,000 infections
MESH:D002318 cardiovascular disease
MESH:D003371 dry cough
MESH:D005221 tiredness
MESH:D005334 fever
MESH:D007239 infected
MESH:D009369 Cancer|cancer
MESH:D011014 pneumonia
MESH:D018352 coronavirus infections
 33525415
Chloroquine and Hydroxychloroquine Interact Differently with ACE2 Domains Reported to Bind with the Coronavirus Spike Protein: Mediation by ACE2 Polymorphism.
Badraoui R, et. al. (2021); Molecules; 2021 Jan 28 ; 26 (3) . doi:10.3390/molecules26030673
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV-2 infected|CoV-2 infection|2019-nCoV infection|Covid-19|SARS-CoV-2 Infection|COVID-19
MESH:C538387 Gastrointestinal absorption High High BBB
MESH:C567116 Drug-Likeness Molecular weight
MESH:D000077195 Head and Neck Squamous Cell Carcinoma
MESH:D001102 virus infection
MESH:D001172 rheumatoid and idiopathic arthritis
MESH:D003643 deaths
MESH:D006333 heart failure
MESH:D007239 malarial infection|infections|infection|infected
MESH:D008180 systemic lupus erythematous
MESH:D008288 malaria
MESH:D009369 cancer|cancers
MESH:D010190 pancreatic cancer
MESH:D010272 parasites
MESH:D012128 Acute respiratory distress syndrome|acute respiratory distress syndrome|ARDS
MESH:D012164 retinopathy
MESH:D012216 rheumatic diseases
MESH:D013733 testicular injury
MESH:D064420 toxicity
 33707363
Contributions of human ACE2 and TMPRSS2 in determining host-pathogen interaction of COVID-19.
Senapati S, et. al. (2021); J Genet; 2021 ; 100
MESH:C000657245 covid-19|SARS-CoV-2 infection|COVID19|novel coronavirus pneumonia|CoV-2 infection|coronavirus disease-19|Covid-19|SARS-CoV infections|2019-nCoV pneumonia|COVID-19
MESH:C538424 HI
MESH:D000848 Abbasi H
MESH:D001281 atrial fibrillation
MESH:D002318 CVD|cardiovascular disease|cardiovascular diseases
MESH:D003141 infectious diseases
MESH:D003643 deaths|death
MESH:D003920 diabetes
MESH:D003924 type-2 diabetes
MESH:D003967 diarrhea
MESH:D006250 Hartnup disorder
MESH:D006331 systolic dysfunction
MESH:D006333 heart failure
MESH:D006973 hypertension
MESH:D007239 infections|infection|infected
MESH:D007674 embryonic kidneys
MESH:D009369 tumor
MESH:D010300 PD
MESH:D011014 pneumonia
MESH:D011471 degradation prostate cancer
MESH:D015430 gain of infection
MESH:D018352 coronavirus infections|coronavirus diseases|respiratory syndrome coronavirus infection|coronavirus infection|Coronavirus Infection|coronavirus tropism
MESH:D018455 Abbasi S
MESH:D045169 severe disease
MESH:D055370 lung injury
MESH:D064752 atrial structural remodelling
OMIM:102510 Al-Abbasi F
 33809265
Interacting Proteins, Polymorphisms and the Susceptibility of Animals to SARS-CoV-2.
Hancock JT, et. al. (2021); Animals (Basel); 2021 Mar 12 ; 11 (3) . doi:10.3390/ani11030797
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|COVID19|SARS-CoV-2 infections|COVID -19|SARS-CoV-2 infected|CoV-2 infection|Covid-19|coronavirus disease 19|COVID-19
MESH:C536108 Sloth Folivora N
MESH:D001102 viral disease|viral infection|virus infected
MESH:D003643 deaths
MESH:D007239 Infection|Infected|infections|infected|infection
MESH:D009102 organ injury
MESH:D011014 pneumonia
MESH:D012128 ARDS
MESH:D012140 respiratory diseases
MESH:D012141 respiratory infection
MESH:D014983 Gorilla Gorilla gorilla XP
MESH:D015047 zoonotic
MESH:D016584 panic
MESH:D018352 MERS
MESH:D020233 Duck Anas platyrhynchos
MESH:D052456 Atlantic Walrus (Odobenus rosmarus) High
rs1019217338
C/T
RAF1 5894 3:12618652 1
 22022266
Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.
Chen Y, et. al. (2011); PLoS Pathog.; 2011 Oct; 7(10) 1002294. doi:10.1371/journal.ppat.1002294
MESH:C564683 S-adenosylhomocysteine
MESH:D001102 viral infection|viral virulence in infection
MESH:D006470 hemorrhagic fever
MESH:D006526 picornaviruses and hepatitis C virus
MESH:D007239 infection
MESH:D013180 SARS-CoV strain WHU
MESH:D013345 SAH
MESH:D018352 coronavirus|Coronavirus|SARS coronavirus nonstructural|respiratory syndrome coronavirus nonstructural|deadly SARS coronavirus|respiratory syndrome coronavirus Nsp15
MESH:D030342 disordered
MESH:D042822 SARS-CoV genome
MESH:D056486 hepatitis viruses
rs1019324840 Affx-446876030
G/C
ACE2 59272 X:15572296 1
 32938937
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.
Sorokina M, et. al. (2020); Sci Data; 2020 09 16 ; 7 (1) 309. doi:10.1038/s41597-020-00652-6
MESH:C000657245 SARS-CoV-2 infection|Novel Coronavirus-Infected Pneumonia|COVID-19
MESH:C536528 vdW-van der
MESH:C564120 000,000 infections
MESH:D002318 cardiovascular disease
MESH:D003371 dry cough
MESH:D005221 tiredness
MESH:D005334 fever
MESH:D007239 infected
MESH:D009369 Cancer|cancer
MESH:D011014 pneumonia
MESH:D018352 coronavirus infections
rs1020453743
T/C
RTN2 6253 19:45494555 2
 33398302
Neutralising antibodies in Spike mediated SARS-CoV-2 adaptation.
Kemp SA, et. al. (2020); medRxiv; 2020 Dec 29 . doi:10.1101/2020.12.05.20241927
MESH:C000657245 SARS-CoV-2 infected|CoV-2 infection|SARS-CoV-2 infection|Covid 19|COVID-19|Covid-19 Severe Pneumonia
MESH:C536108 N+T
MESH:D000361 hypogammaglobulinemia
MESH:D001102 virus infection
MESH:D002303 falling
MESH:D003141 infectious disease
MESH:D003643 death
MESH:D006086 versus
MESH:D006816 HD
MESH:D007239 infections|infection
MESH:D009102 multi-organ failure
MESH:D009369 cancer
MESH:D012640 fitness
MESH:D015658 HIV-1 infection
 33545711
SARS-CoV-2 evolution during treatment of chronic infection.
Kemp SA, et. al. (2021); Nature; 2021 Feb 05 . doi:10.1038/s41586-021-03291-y
MESH:C000657245 SARS-CoV-2 infected|CoV-2 infection|COVID-19 pneumonia|SARS-CoV-2 infection|COVID-19|Covid-19 Severe Pneumonia
MESH:C536108 N+T
MESH:D000163 NIH AIDS
MESH:D001102 virus infection
MESH:D003141 infectious disease
MESH:D003643 death
MESH:D006816 HD
MESH:D007153 immunodeficiency
MESH:D007239 infection
MESH:D007249 inflammation
MESH:D008223 lymphoma
MESH:D009102 multi-organ failure
MESH:D009369 cancer
MESH:D015658 HIV-1 infection
MESH:D016393 marginal B cell lymphoma
MESH:D065630 congenital diaphragmatic hernia
rs1021340095
G/A,T
OAS1 4938 12:112908744 3
 32771700
Functional prediction and comparative population analysis of variants in genes for proteases and innate immunity related to SARS-CoV-2 infection.
Klaassen K, et. al. (2020); Infect Genet Evol; 2020 10 ; 84 104498. doi:10.1016/j.meegid.2020.104498
MESH:C000657245 covid-19|SARS-CoV-2 infection|SARS-CoV infection|COVID-19
MESH:C565965 TSI IBS CEU GBR FIN EAS SAS AFR AMR SRB|TSI IBS FIN GBR CEU EAS SAS AFR AMR PLG
MESH:D000077277 esophageal squamous cell carcinoma
MESH:D001102 viral diseases|viral infection|viral infections
MESH:D003141 infectious diseases
MESH:D003550 cystic fibrosis
MESH:D003643 mortality|death
MESH:D003922 type I diabetes
MESH:D007239 infections|infection|infected
MESH:D009103 multiple sclerosis
MESH:D010195 pancreatitis
MESH:D011014 pneumonia
MESH:D012120 acute respiratory syndrome|acute respiratory syndrome coronavirus infection
MESH:D012140 respiratory disease
MESH:D012598 sclerosis
MESH:D015658 HIV infection|HIV-1 infection|human diseases or disorders
MESH:D016098 GSD
MESH:D018352 respiratory syndrome coronavirus infection
MESH:D030342 Mendelian diseases
MESH:D045169 severe acute respiratory syndrome
MESH:D055744 invasive aspergillosis
 33396584
Markers Associated with COVID-19 Susceptibility, Resistance, and Severity.
Fakhroo AD, et. al. (2020); Viruses; 2020 Dec 30 ; 13 (1) . doi:10.3390/v13010045
MESH:C000657245 SARS-CoV-2 pneumonia|covid-19|coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV-2 respiratory failure|novel coronavirus disease|novel coronavirus pneumonia|SARS-CoV-1 infection|CoV-2 infection|new coronavirus pneumonia|Covid-19|SARS-CoV-2 Infection|COVID-19
MESH:C536778 SCD
MESH:D000067390 cold
MESH:D000860 hypoxemia
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001145 ventricular arrhythmia
MESH:D001249 asthma
MESH:D001327 autoimmune disease
MESH:D001424 pulmonary bacterial infection|bacterial infection
MESH:D002318 cardiovascular disorders|cardiovascular disease|cardiovascular diseases
MESH:D002561 cerebrovascular diseases
MESH:D002908 chronic diseases|chronic disease
MESH:D003139 common cold infections
MESH:D003141 infectious diseases
MESH:D003643 mortality|Mortality|deaths|death
MESH:D003920 diabetes|acute Diabetes|diabetic|Diabetes
MESH:D003967 Diarrhea
MESH:D005767 gastrointestinal infections
MESH:D006261 humidity rise
MESH:D006331 cardiac disease
MESH:D006943 hyperglycemia
MESH:D006973 Celsius increase|hypertension
MESH:D007003 hypoglycemia|Hypoglycemia
MESH:D007153 immunodeficiency
MESH:D007239 rhinovirus infection|infections|infected|infection
MESH:D007249 inflammation
MESH:D007674 kidney diseases
MESH:D008171 asthmatic chronic pulmonary disease
MESH:D008180 deficiency in lupus|lupus
MESH:D009102 multiple organ failure
MESH:D009369 malignancy
MESH:D009765 obesity|obese
MESH:D010182 pancreatic damage
MESH:D010195 pancreatitis
MESH:D011014 lung inflammation
MESH:D012128 acute respiratory distress syndrome|ARDS|respiratory distress|sepsis and the acute respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 respiratory tract infections|respiratory and intestinal infections|respiratory infections
MESH:D015047 zoonotic
MESH:D015658 HIV-infected
MESH:D016638 critically ill
MESH:D016757 sudden cardiac death
MESH:D018352 coronavirus infections|coronavirus disease|multiple coronavirus infections|Coronavirus Disease|CoV infection
MESH:D019965 organ damage
MESH:D029424 Chronic obstructive pulmonary disease|COPD
MESH:D051271 lower cold symptoms
MESH:D051436 chronic kidney disease
MESH:D056486 hepatic injury
MESH:D064806 dysbiosis
 33590936
Genetic and epigenetic factors associated with increased severity of Covid-19.
Yildirim Z, et. al. (2021); Cell Biol Int; 2021 Feb 16 . doi:10.1002/cbin.11572
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|novel coronavirus pneumonia|2019 novel coronavirus diseases|SARS-CoV-2 infections|CoV-2 infection|2019-nCoV infection|SARS-CoV-2-infected|COVID-19|Coronavirus disease 2019|SARS-CoV-Infected|SARS-CoV-2 infected|SARS-Cov-2 infection|coronavirus disease-2019|Covid-19|SARS-CoV-2 Infection|coronavirus disease 2019 pneumonia|COVID19 lethality
MESH:C536170 DD
MESH:C566739 autosomal-dominant deficiencies
MESH:D000067390 cold
MESH:D000544 Alzheimer's disease
MESH:D000860 hypoxia
MESH:D001102 viral disease|viral infection|virus infection|viral infections
MESH:D001778 coagulation
MESH:D002318 cardiovascular disease
MESH:D003139 common cold
MESH:D003643 mortality|Mortality|Death|deaths|mortalities|death
MESH:D003920 diabetes|diabetes mellitus|diabetic
MESH:D003924 Type 2 diabetes
MESH:D005355 fibrosis
MESH:D006526 HCV infection|hepatitis C virus infection
MESH:D006566 B infection
MESH:D006973 hypertension
MESH:D007153 deficiency
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D007674 nondiabetic kidney disease|Collapsing glomerulopathy|Collapsing Glomerulopathy|glomerulopathy
MESH:D008180 lupus
MESH:D008661 Inborn errors of type I
MESH:D009102 multi-organ failure
MESH:D009103 familial multiple sclerosis
MESH:D009369 malignancy|cancer
MESH:D009422 neurological disorders
MESH:D011014 pneumonia|pneumonitis
MESH:D011471 prostate cancer
MESH:D012128 ARDS|acute respiratory distress syndrome|respiratory distress
MESH:D012131 respiratory failure
MESH:D012598 sclerosis
MESH:D012772 septic shock
MESH:D013927 thrombosis
MESH:D016638 critical illness|critical disease
MESH:D016893 Deficiency of IFNARs narrow
MESH:D018243 teratocarcinoma
MESH:D018352 coronavirus infections|respiratory syndrome coronavirus infection|human coronavirus infections
MESH:D018805 sepsis
MESH:D019698 chronic hepatitis C infection|chronic hepatitis C
MESH:D030342 inherited TLR3 deficiency
MESH:D045169 severe acute respiratory syndrome
MESH:D050197 atherosclerosis
MESH:D051436 chronic kidney disease
MESH:D054556 venous thromboembolism|Venous thromboembolism
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D058186 Acute kidney injury
MESH:D060085 immunodeficiency virus coinfected
rs10235056
G/A
GPER1 2852 7:1093112 1
 33748487
Association between GPER gene polymorphisms and GPER expression levels with cancer predisposition and progression.
Ulhaq ZS, et. al. (2021); Heliyon; 2021 Mar ; 7 (3) 06428. doi:10.1016/j.heliyon.2021.e06428
MESH:C000657245 SARS-CoV-2 infection|novel coronavirus pneumonia|COVID-19
MESH:D000230 adenocarcinoma
MESH:D001943 endometrial and breast cancer|breast carcinoma|breast cancer|Gynaecomastia and breast cancer|primary breast cancers|Breast cancer
MESH:D002289 NSCLC|non-small cell lung cancer
MESH:D002296 carcinosarcoma
MESH:D003704 dementia
MESH:D003924 type 2 diabetes mellitus
MESH:D004715 endometriosis
MESH:D005128 ocular disease|ocular diseases
MESH:D005901 glaucoma
MESH:D005902 open-angle glaucoma
MESH:D006106 ovarian granulosa cell tumors|Ovarian Granulosa Cell Tumors
MESH:D006177 Gynecomastia|gynecomastia
MESH:D007889 leiomyoma|leiomyoma Turkey
MESH:D008175 lung cancer
MESH:D008949 malignant salivary gland tumors
MESH:D009369 tumor|malignancies|Cancer type Tumor|cancerous|aggressiveness of malignancies|cancer|cancers|carcinoma|cancer type/disease|neoplasms|multiple cancers|cancer aggressiveness
MESH:D009798 intraocular
MESH:D010051 ovaries|ovarian cancer
MESH:D010300 Parkinson's disease
MESH:D012162 degeneration
MESH:D013274 gastric cancer|Gastric cancer
MESH:D016889 endometrial carcinoma|Endometrial cancer|endometrial cancer|endometrial cancers
MESH:D018239 seminoma
MESH:D018567 male breast disorder|male breast cancer
MESH:D024821 metabolic syndrome
MESH:D062788 Adenomyosis|adenomyosis|leiomyoma and adenomyosis
OMIM:181800 adolescent idiopathic scoliosis
rs1024611 Affx-13775760
A/G
LINC01989 101927239 17:34252769 7
 25818534
Functional polymorphisms of the CCL2 and MBL genes cumulatively increase susceptibility to severe acute respiratory syndrome coronavirus infection.
Tu X, et. al. (2015); J. Infect.; 2015 Jul; 71(1) 101-9. doi:10.1016/j.jinf.2015.03.006
MESH:C000657245 SARS-CoV infection
MESH:C563602 MBL deficiency|MBL AB
MESH:D001102 viral infection
MESH:D002908 chronic diseases
MESH:D003141 Infectious Diseases|infectious disease|infectious diseases
MESH:D003586 cytomegalovirus reactivation
MESH:D003643 deaths|died
MESH:D003704 dementia
MESH:D006526 HCV infection
MESH:D007239 infected|infection
MESH:D007249 inflammation
MESH:D007896 leishmaniasis
MESH:D008107 liver disease
MESH:D009102 organ dysfunction|multi-organ dysfunction
MESH:D009203 myocardial infarction
MESH:D012120 acute respiratory syndrome|acute respiratory syndrome coronavirus infection
MESH:D014397 pulmonary tuberculosis
MESH:D015526 AIDS dementia
MESH:D015658 HIV infection|HIV-1 infection|HIV-1-infected
MESH:D018352 SARS-coronavirus-infected|respiratory syndrome coronavirus infection|SARS coronavirus infection
MESH:D020022
MESH:D045169 SARS|severe acute respiratory syndrome|Severe acute respiratory syndrome
MESH:D055370 lung injury
 32480226
Effects of host genetic variations on response to, susceptibility and severity of respiratory infections.
Ghafouri-Fard S, et. al. (2020); Biomed. Pharmacother.; 2020 Aug ; 128 110296. doi:10.1016/j.biopha.2020.110296
MESH:C000657245 CoV-2 infection|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV infection|COVID-19
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001988 bronchiolitis|TLR9 Bronchiolitis
MESH:D003141 infectious diseases
MESH:D003643 mortality|death
MESH:D007239 RSV infection|infections|infection|infected
MESH:D009369 cancer
MESH:D009461 dysfunction
MESH:D011008 Pneumococcal disease|Pneumococcal diseases
MESH:D011014 pneumonia
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 Acute respiratory distress syndrome|TNFalpha ARDS|acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory disorders
MESH:D012141 respiratory tract infections|respiratory infections
MESH:D012772 Septic shock|Pneumococcal septic shock|septic shock
MESH:D014376 Tuberculosis|tuberculosis
MESH:D014397 pulmonary tuberculosis|Pulmonary tuberculosis
MESH:D016638 septic pediatric critically ill
MESH:D018352 respiratory syndrome coronavirus infection
MESH:D018805 Sepsis|sepsis
 33133166
Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis.
Smatti MK, et. al. (2020); Front Genet; 2020 ; 11 578523. doi:10.3389/fgene.2020.578523
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|SARS-CoV-1 infected|SARS-CoV-infected|SARS-CoV-2 infections|SARS-CoV-1 infection|CoV-2 infections|COVID-19
MESH:C538098 Paget's disease
MESH:D001102 viral infections
MESH:D001281 AF
MESH:D003141 infectious diseases
MESH:D003643 mortality|death
MESH:D006509 hepatitis B|hepatitis B virus infection
MESH:D007239 Infection|infections|infection
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012141 respiratory infections
MESH:D015211 CHR
MESH:D018352 SARS-coronavirus-infected
MESH:D045169 severe acute respiratory syndrome|SARS illness
 33158051
Threading the Pieces Together: Integrative Perspective on SARS-CoV-2.
Kanakan A, et. al. (2020); Pathogens; 2020 Nov 04 ; 9 (11) . doi:10.3390/pathogens9110912
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|SARS-CoV infection|coronavirus disease 2019|SARS-CoV-2 infections|novel coronavirus pneumonia|Coronavirus Pneumonia 2019|SARS-CoV-2-infected|COVID 19|Novel Coronavirus-Infected Pneumonia|COVID-19|2019 Novel Coronavirus-Infected Pneumonia|COVID|SARS-CoV-2 pneumonia|COVID-2019|Novel Coronavirus Pneumonia|SARS-CoV-1 infection|SARS-CoV-2 infected|COVID-19 Pneumonia|Co-infection of Coronavirus Disease 2019|Covid-19|coronavirus-infected disease 2019|coronavirus (2019-nCoV) infected pneumonia|coronavirus disease 2019 pneumonia
MESH:C535297 respiratory papillomatosis
MESH:C535729 dyschromatosis symmetrica hereditaria
MESH:C538007 Abnormal variations
MESH:C566808 Phagocytosis via complement
MESH:D000073397 Catalonia Working
MESH:D000079225 hypoxic stress
MESH:D000857 anosmia
MESH:D000860 hypoxemia
MESH:D001102 viral co-infections|Host-Viral Infection|viral infection|virus infection|viral infections
MESH:D001424 bacterial infection
MESH:D001991 bronchitis virus
MESH:D002318 cardiovascular disease|cardiovascular diseases
MESH:D003141 infectious disease|infectious diseases
MESH:D003316 corneal
MESH:D003324 coronary injury
MESH:D003371 dry cough
MESH:D003586 cytomegalovirus infection|Cytomegalovirus infection
MESH:D003643 mortality|death|mortal
MESH:D003920 diabetes|diabetes mellitus|Diabetic|diabetic|Diabetes mellitus|Diabetes
MESH:D003924 Type 2-diabetes|type 2 diabetes mellitus
MESH:D003928 diabetic glomerulopathy
MESH:D003967 diarrhea
MESH:D005334 fever
MESH:D006323 cardiac arrest
MESH:D006332 cardiac hypertrophy
MESH:D006470 hemorrhage
MESH:D006509 HBV infection
MESH:D006526 hepatitis C virus infection
MESH:D006943 hyperglycemia|Hyperglycemia
MESH:D006973 Hypertension|hypertension|hypertensive
MESH:D006976 pulmonary hypertension
MESH:D007239 Infections|Common infections|infection|Infection|brain infections|systemic infection|Infected|infections|infections/diseases|infected
MESH:D007249 inflammation|Metabolic Inflammation
MESH:D007674 kidney diseases|renal damage and dysfunction|glomerular injuries
MESH:D007938 leukemia viruses
MESH:D008231 lymphocytopenia
MESH:D008288 malaria parasites
MESH:D008661 inborn errors
MESH:D009102 multiple organ failure
MESH:D009181 fungal infections
MESH:D009202 myocardial injury
MESH:D009223 DM
MESH:D009325 nausea
MESH:D009336 tumor necrosis
MESH:D009422 hyperglycaemic damage
MESH:D010608 pharyngalgia
MESH:D011014 Pneumonia|pneumonia|idiopathic pneumonia
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 Respiratory Failure|respiratory failure|respiratory disorders
MESH:D012140 respiratory diseases|respiratory disease
MESH:D012772 septic shock
MESH:D012817 gastrointestinal symptoms
MESH:D013290 streptococcal soft-tissue infections
MESH:D013927 thrombus
MESH:D014839 vomiting
MESH:D015047 zoonotic
MESH:D015658 HIV-1 infection
MESH:D015746 abdominal pain
MESH:D016638 critical illness
MESH:D017093 necrosis in the liver and pulmonary perivascular hemorrhage
MESH:D018352 Coronavirus infections|respiratory syndrome coronavirus infection|coronavirus-infected
MESH:D029424 chronic obstructive pulmonary disease|COPD
MESH:D030361 papillomavirus type
MESH:D048909 diabetic complications
MESH:D051437 renal failure
MESH:D055370 lung injury
MESH:D056486 hepatitis coronavirus
MESH:D057165 proteostasis
MESH:D058186 acute renal injury
MESH:D060085 co-infections|secondary infection|Co-Infection|co-infection|fungal co-infections|Co-infection|Co-infections
MESH:D061325 syndromic
MESH:D063806 myalgia
MESH:D064420 cytotoxicity
 33342718
Macrophage-derived cytokines in pneumonia: Linking cellular immunology and genetics.
Dukhinova M, et. al. (2020); Cytokine Growth Factor Rev; 2020 Dec 03 . doi:10.1016/j.cytogfr.2020.11.003
MESH:C000657245 COVID-19 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|COVID19|COVID19 disease|novel coronavirus pneumonia|SARS-CoV-Infected|SARS-CoV-2-Infected|SARS-CoV-2-infected|Covid-19|COVID-19|new coronavirus disease
MESH:C537409 Stat-1 deficiency
MESH:C563662 Invasive pneumococcal disease|invasive pneumococcal disease
MESH:C565292 atopic asthma
MESH:C567070 deficiency mycobacterial disease
MESH:D000081207 Primary Immunodeficiencies
MESH:D000755 sickle cell disease
MESH:D001102 Virus Infection|virus infection|viral infection|viral infections
MESH:D001170 septic complications
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma|adult asthma
MESH:D001327 autoimmunity|autoimmune disease|autoimmune diseases
MESH:D001424 bacterial infection
MESH:D001766 complete IRF9 deficiency
MESH:D001943 breast Cancer|breast cancer|Breast cancer
MESH:D002318 cardiovascular disorders|cardiovascular and metabolic disorders|cardiovascular damage
MESH:D003141 Monogenic Diseases|infectious diseases|Infectious disease
MESH:D003550 cystic fibrosis
MESH:D003643 mortality
MESH:D003920 diabetes|diabetes mellitus|diabetic|Diabetes
MESH:D003924 type 2 diabetes mellitus
MESH:D003928 Diabetic nephropathy|diabetic nephropathy
MESH:D005355 fibrosis|lung fibrosis
MESH:D005910 asthma in glioma
MESH:D006509 hepatitis B, hepatitis C
MESH:D006937 hypercholesterolemia
MESH:D006976 pulmonary hypertension
MESH:D007153 PPARgamma deficiency|deficiency|immunodeficiency
MESH:D007154 immune disorders
MESH:D007239 Infection|Infections|Tuberculosis infection|infections|infection|infected
MESH:D007249 allergic airway inflammation|inflammation|Inflammation
MESH:D008171 lung dysfunction|lung disease|lung damage|lung immunoparalysis
MESH:D008175 lung cancer|lung Cancer|Lung tumors
MESH:D008180 systemic lupus erythematosus|SLE
MESH:D008545 melanoma
MESH:D008581 Meningitis
MESH:D008586 pneumococcal meningitis
MESH:D008659 metabolic disorders
MESH:D008661 Inborn errors
MESH:D009102 multiorganic failure|systemic organ failure
MESH:D009202 cardiomyopathy|Inflammatory cardiomyopathy
MESH:D009336 tumor necrosis
MESH:D009369 Cancer|cancer|tumor
MESH:D009461 dysfunctional
MESH:D010051 ovarian cancer
MESH:D010149 postoperative pneumonia|Postoperative pneumonia
MESH:D011008 pneumococcal pneumonia
MESH:D011014 pneumonias|comorbidity-pneumonia|pneumonia|pneumonitis|Pneumonia|Lung inflammation|pulmonary inflammation|pulmonary inflammatory diseases|lung inflammation
MESH:D011020 Pneumocystis pneumonia|Pneumocystis jirovecii pneumonia
MESH:D011471 prostate cancer aggressiveness|prostate cancer
MESH:D011649 alveolar proteinosis|pulmonary alveolar proteinosis
MESH:D011655 pulmonary obstruction
MESH:D011658 pulmonary fibrosis
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 respiratory distress syndrome|acute respiratory distress syndrome
MESH:D012131 respiratory failure|lung fibrosis and organ failure
MESH:D012140 respiratory disease
MESH:D012141 lung infections|Respiratory infection|Lung infection
MESH:D012595 systemic sclerosis
MESH:D012772 septic shock
MESH:D012857 pulmonary tissue damage in SIV-infected
MESH:D014095 impacts disease
MESH:D014947 trauma
MESH:D015212 inflammatory bowel disease
MESH:D015472 acute eosinophilic pneumonia
MESH:D015499 functional deficiency
MESH:D016920 bacterial pneumonia|bacterial pneumonias
MESH:D018357 Respiratory Syncytial Virus Infected|respiratory syncytial virus infection
MESH:D018805 Sepsis|sepsis
MESH:D020814 Escherichia coli pneumonia
MESH:D024821 metabolic syndrome
MESH:D029424 Chronic obstructive lung disorder|chronic obstructive pulmonary disease|COPD|asthma and chronic obstructive airways disease
MESH:D030342 inborn|inherited IRF9 deficiency
MESH:D034721 Systemic disorders
MESH:D045169 severe disease
MESH:D054243 oncolytic vesicular stomatitis|Oncolytic vesicular stomatitis
MESH:D055370 lung injury|pulmonary injury
MESH:D056586 acute chest syndrome|chest syndrome
 33933633
Genetic polymorphisms as multi-biomarkers in severe acute respiratory syndrome (SARS) by coronavirus infection: A systematic review of candidate gene association studies.
Dos Santos ACM, et. al. (2021); Infect Genet Evol; 2021 Apr 29 104846. doi:10.1016/j.meegid.2021.104846
MESH:C000657245 covid-19|SARS-COV-2 infections|SARS-Cov infection|SARS-CoV infection|Covid-19|COVID-19
MESH:C566056 APCs
MESH:D000071069 hypoxic conditions
MESH:D000071074 neonatal sepsis and pneumonia
MESH:D000163 AIDS
MESH:D000783 vascular disease|cerebral vascular disease
MESH:D000860 hypoxemia|hypoxia
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001327 autoimmunity|autoimmune diseases
MESH:D002318 cardiovascular system
MESH:D002561 vascular dysfunction
MESH:D003092 colitis
MESH:D003093 ulcerative colitis
MESH:D003141 infectious diseases
MESH:D003324 coronary artery disease
MESH:D003371 dry cough
MESH:D003643 mortality|died|death
MESH:D003715 dengue disease
MESH:D003920 diabetes mellitus
MESH:D003924 Type 2 Diabetes Mellitus
MESH:D004417 dyspnea
MESH:D004487 alveolar edema
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D005355 fibrosis
MESH:D006470 hemorrhage
MESH:D006509 viral hepatitis B
MESH:D006526 HCV infection|cirrhosis, hepatitis C
MESH:D006800 HTLV-1 infection
MESH:D006973 hypertension
MESH:D007239 infections|infection|infected
MESH:D007249 inflammation|Inflammation
MESH:D007896 tegumentary leishmaniasis
MESH:D007918 leprosy
MESH:D008288 malaria
MESH:D009102 injury and organ failure
MESH:D009223 DM
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D011014 pneumonia
MESH:D011658 pulmonary fibrosis|fibrosis pulmonary
MESH:D012120 acute respiratory syndrome|acute respiratory syndrome coronavirus infection
MESH:D012128 adult respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory diseases
MESH:D012141 respiratory tract infections
MESH:D012772 septic shock
MESH:D014376 tuberculosis
MESH:D014397 pulmonary tuberculosis
MESH:D015440 lepromatous leprosy
MESH:D015658 HIV
MESH:D016638 critically ill
MESH:D018352 coronavirus infections|coronavirus disease|respiratory syndrome coronavirus infection|SARS coronavirus infection|Middle East respiratory syndrome|coronavirus infection|MERS|Coronavirus disease
MESH:D018805 sepsis
MESH:D019595 dengue hemorrhagic fever
MESH:D020521 stroke
MESH:D029424 chronic obstructive pulmonary disease|COPD
MESH:D045169 SARS|severe acute respiratory syndrome|SARS-COV infection|Severe acute respiratory syndrome
MESH:D050197 atherosclerosis
MESH:D051271 hypercoagulability and endotheliopathy symptoms
MESH:D051436 chronic kidney disease
MESH:D054990 idiopathic pulmonary fibrosis
MESH:D055370 lung injury
MESH:D056486 hepatitis
MESH:D059366 occupational asthma
MESH:D064420 toxicity
 33934196
Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection.
Hashemi SMA, et. al. (2021); Arch Virol; 2021 May 02 . doi:10.1007/s00705-021-05070-6
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV infection|COVID19|SARS-CoV-2 infections|novel coronavirus pneumonia|CoV-2 infection|novel coronavirus infections|SARS-CoV-2-infected|COVID-19|new coronavirus disease|SARS-CoV-1 infection Itoyama|Coronavirus disease 2019|2019 infection|SARS-CoV-1 infection outcome Patarcic|SARS-CoV-1 infection|Covid-19|coronavirus disease-2019
MESH:C535882 Johnson L
MESH:C536174 panbronchiolitis
MESH:C538614 renal cell carcinoma
MESH:C564969 multi-organ disease
MESH:C567355 immunodeficiency virus-mediated syncytia
MESH:D000544 Alzheimer's disease|Alzheimer disease
MESH:D000860 hypoxemia|hypoxia
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001424 bacterial infections
MESH:D001847 bone homeostasis
MESH:D001943 breast cancer
MESH:D002318 cardiovascular disease|cardiovascular systems|cardiovascular diseases
MESH:D002537 atherosclerotic cerebral infarction
MESH:D002544 acute cerebral infarction
MESH:D002908 rhinovirus illness
MESH:D003141 atherothrombotic disease|infectious diseases
MESH:D003428 nosocomial infection
MESH:D003643 mortality|deaths|mortalities|death|mortal
MESH:D003920 diabetes|diabetes mellitus
MESH:D003924 type 2 diabetes|type 2 diabetes mellitus
MESH:D004194 multiple diseases and disorders|numerous diseases and disorders
MESH:D004487 alveolar edema
MESH:D004646 emphysema
MESH:D004675 tick-borne encephalitis
MESH:D005355 fibrosis
MESH:D005921 glomerulosclerosis
MESH:D006331 congenital heart disease
MESH:D006333 heart failure
MESH:D006461 hemolysis
MESH:D006509 hepatitis B virus infection|hepatitis B
MESH:D006526 HCV infection|hepatitis C virus (HCV) infection|hepatitis C virus infection|hepatitis C viral infection
MESH:D006973 hypertension|hypertensive
MESH:D007239 Decreased infection|infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 Collapsing glomerulopathy|kidney disease|nondiabetic nephropathy|glomerulopathy
MESH:D008103 hepatic fibrosis
MESH:D008171 pulmonary damage|lung disease|lung damage
MESH:D008288 malaria parasites
MESH:D008545 melanoma|malignant melanoma
MESH:D008659 metabolic disorders
MESH:D008661 Inborn errors of type I
MESH:D009103 multiple sclerosis
MESH:D009336 tumour necrosis
MESH:D009362 metastasis of tumors
MESH:D009369 cancerous|cancer|cancers|tumor|carcinoma
MESH:D009393 nephritis
MESH:D010051 ovaries
MESH:D010190 invasiveness of pancreatic cancer
MESH:D010300 PD
MESH:D011014 pneumonia|lung inflammation
MESH:D011471 prostate cancer metastasis|NCI-H660 prostate cancer|prostate cancer|aggressive prostate cancer|sporadic prostate cancer
MESH:D011565 psoriasis
MESH:D011654 pulmonary edema
MESH:D011658 pulmonary fibrosis
MESH:D011660 hypoxaemic cor pulmonale
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome|ARDS|adult respiratory distress syndrome
MESH:D012131 respiratory failure|pulmonary failure
MESH:D012140 chronic respiratory disease|respiratory disease
MESH:D012141 respiratory viruses infections|upper respiratory tract infections
MESH:D012598 sclerosis
MESH:D012769 shock
MESH:D012871 skin diseases
MESH:D013927 thrombotic
MESH:D015140 vascular dementia
MESH:D015179 colorectal cancer
MESH:D015619 respiratory system edema
MESH:D015658 HIV infection|HIV-1 infection
MESH:D016638 critical illness|critically ill
MESH:D018352 MERS-CoV infection|respiratory syndrome coronavirus infection|coronavirus disease|SARS coronavirus infection|CoV-1 infection|coronavirus infection|Coronavirus infection|Middle East respiratory syndrome-coronavirus infection
MESH:D019698 chronic hepatitis C virus infection
MESH:D020258 neurotoxicity
MESH:D045169 severe acute respiratory syndrome|SARS infection
MESH:D050197 atherosclerotic|atherosclerosis|atherosclerotic lesions
MESH:D051436 chronic kidney disease
MESH:D054058 acute coronary syndrome
MESH:D054990 idiopathic pulmonary fibrosis
MESH:D055370 lung injury
MESH:D055371 acute lung failure|acute lung injury
MESH:D058186 Acute kidney injury
MESH:D059446 asplenia
rs10246939 Affx-29854785
T/C
TAS2R38 5726 7:141972804 1
 33582215
COVID-19 as a worldwide selective event and bitter taste receptor polymorphisms: An ecological correlational study.
();
MESH:C000657245 SARS-CoV-2 infection|Coronavirus 2019 disease|Covid-19|COVID-19
MESH:D000370 ageusia
MESH:D000402 obstruction
MESH:D000437 alcoholism
MESH:D000857 anosmia
MESH:D001102 Viral infections
MESH:D001249 asthma
MESH:D001424 bacterial infections
MESH:D001778 coagulopathy
MESH:D001982 bronchial disease
MESH:D002908 chronic rhinosinusitis
MESH:D003141 infectious diseases
MESH:D003371 cough
MESH:D003643 mortality|deaths|death
MESH:D004067 gastrointestinal cancers
MESH:D004342 asthmatic allergic
MESH:D006261 headaches
MESH:D006973 hypertension
MESH:D007239 infections
MESH:D007249 inflammation
MESH:D009059 oral mucosal diseases
MESH:D009369 malignant cancer
MESH:D009765 obesity
MESH:D009845 azoospermia and oligospermia in idiopathic infertile men
MESH:D011014 pneumonia
MESH:D012141 respiratory infection|upper respiratory infection|upper respiratory tract
MESH:D012220 rhinitis
MESH:D013651 taste disorders
MESH:D015179 colorectal cancer|colorectal adenoma
MESH:D015508 nasal obstruction
MESH:D016751 Siasi E
MESH:D018352 coronavirus infections|MERS|Coronavirus Disease Dashboard
MESH:D030342 genetic disorders
MESH:D063806 body aches
rs1024914515
C/T
CARD17 440068 11:105100707 1
 33467177
Structure, Activation and Regulation of NLRP3 and AIM2 Inflammasomes.
Sharma M, et. al. (2021); Int J Mol Sci; 2021 Jan 16 ; 22 (2) . doi:10.3390/ijms22020872
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|Coronavirus disease 2019|COVID-19 Coronavirus disease|2019 DAMPs|COVID-19
MESH:C535884 articular syndrome
MESH:C536657 Silencing-1 TNF Tumor
MESH:C537792 axial rise
MESH:C538437 Familial cold auto- inflammatory syndrome
MESH:C566065 silently deadly
MESH:C566796 Signal Diseases Structure Canonical Inflammasomes
MESH:C579880 filamentous inflammasome
MESH:D000067390 cold
MESH:D000544 Alzheimer's disease
MESH:D000690 amyotrophic lateral sclerosis|Amyotrophic lateral sclerosis
MESH:D001007 anxiety
MESH:D001102 viral infection
MESH:D001168 arthritis
MESH:D001172 Rheumatoid arthritis
MESH:D001327 autoimmune disease|autoimmune diseases|autoimmune syndrome
MESH:D001424 bacterial infections
MESH:D001930 ischemic brain injury
MESH:D002006 Brucella joint infection
MESH:D002546 ischemic brain damage
MESH:D003092 colitis|Colitis
MESH:D003110 colonic mucosa|colonic
MESH:D003141 Infectious Diseases
MESH:D003643 DEDs Death|death of lymphoid|Death|deaths|pyroptosis cell death
MESH:D003711 demyelination
MESH:D003920 diabetes
MESH:D003924 type II diabetes
MESH:D004342 Allergy
MESH:D004405 Shigella-infected
MESH:D004760 Cytosolic flagellin Syndrome of enterocolitis
MESH:D006816 HD
MESH:D007239 infections|infection|infected
MESH:D007249 inflammatory diseases|inflammation|inflammatory disease
MESH:D007645 palmoplantar carcinoma
MESH:D007896 Leishmania|Leishmania parasite
MESH:D008180 systemic lupus erythematosus|HIV infections Systemic lupus erythematosus|SLE
MESH:D008181 lupus nephritis
MESH:D008223 lymphoid tissue lymphoma
MESH:D008545 melanoma|melanoma 2 ALRs
MESH:D008659 metabolic disorder|metabolic disorders
MESH:D009103 Multiple sclerosis
MESH:D009369 cancer|tumor
MESH:D009461 PTM dysfunction
MESH:D009765 OB Oligonucleotide|OB
MESH:D010300 Parkinson's disease
MESH:D010505 familial Mediterranean fever|periodic syndrome|periodic syndrome CARD|autoinflammatory diseases FMF|Familial Mediterranean Fever|Familial Mediterranean fever|FMF
MESH:D010930 Yersinia pestis
MESH:D011565 Psoriasis
MESH:D012140 respiratory diseases
MESH:D012216 Rheumatism
MESH:D012480 salmonella-infected
MESH:D012514 Kaposi Sarcoma-associated herpesvirus infection
MESH:D012772 endotoxic shock
MESH:D014123 Toxoplasma gondii infection
MESH:D015179 colorectal cancer|colonic cancer
MESH:D015212 inflammatory bowel disease|Inflammatory bowel diseases|Inflammatory bowel disease
MESH:D015473 promyelocytic leukemia
MESH:D015658 HIV
MESH:D016393 B-cell lymphoma
MESH:D016463 neutrophilic dermatosis|Neutrophilic Dermatosis
MESH:D017514 familial keratosis lichenoides chronica
MESH:D017544 lymphocytic infiltrates of abdominal aortic aneurysms|abdominal aortic aneurysm
MESH:D019337 HIN Hematopoietic
MESH:D019636 neurodegeneration
MESH:D019871 dyskeratosis
MESH:D020521 stroke
MESH:D029424 Chronic obstructive pulmonary disease|COPD
MESH:D030342 inherited diseases|cardiometabolic disorders
MESH:D045169 severe acute respiratory syndrome
MESH:D054078 HIDS
MESH:D055370 lung injury
MESH:D055501 Macrophage activation syndrome
MESH:D056587 FCAS|Familial cold|chronic infantile neurological cutaneous and articular syndrome|chronic infantile neurologic|familial cold autoinflammatory syndrome|multisystem inflammatory disease
MESH:D056660 hereditary periodic fever syndromes|autoinflammatory syndromes|autoinflammatory syndrome|periodic fever syndrome|autoinflammatory diseases
MESH:D064128 NODs
OMIM:191900 Muckle-Wells syndrome|MWS
OMIM:616050 enterocolitis and autoinflammation
OMIM:617388 arthritis and dyskeratosis
rs1025682991
G/A
IRF7 3665 11:613809 1
 33811212
Genetic variability in COVID-19-related genes in the Brazilian population.
Secolin R, et. al. (2021); Hum Genome Var; 2021 Apr 02 ; 8 (1) 15. doi:10.1038/s41439-021-00146-w
MESH:C000657245 CoV-2 infection|COVID-19 pneumonia|SARS-CoV-2 infection|covid|Covid-19|coronavirus disease-2019|COVID-19
MESH:C566345 AFND
MESH:D001102 viral infections
MESH:D001281 AF
MESH:D003139 common epilepsies
MESH:D003141 infectious disease|infectious diseases
MESH:D003643 mortality|deaths|death
MESH:D004660 encephalitis
MESH:D006816 HD
MESH:D007239 infections|infection|infected
MESH:D008589 meningococcal disease|invasive meningococcal disease
MESH:D008661 Inborn errors of type I
MESH:D012131 Respiratory Failure|respiratory failure
MESH:D018352 respiratory syndrome coronavirus entry
rs1027571965 Affx-937751416
G/A,C
ACE2 59272 X:15566349 2
 32938937
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.
Sorokina M, et. al. (2020); Sci Data; 2020 09 16 ; 7 (1) 309. doi:10.1038/s41597-020-00652-6
MESH:C000657245 SARS-CoV-2 infection|Novel Coronavirus-Infected Pneumonia|COVID-19
MESH:C536528 vdW-van der
MESH:C564120 000,000 infections
MESH:D002318 cardiovascular disease
MESH:D003371 dry cough
MESH:D005221 tiredness
MESH:D005334 fever
MESH:D007239 infected
MESH:D009369 Cancer|cancer
MESH:D011014 pneumonia
MESH:D018352 coronavirus infections
 33370311
ACE2 polymorphisms as potential players in COVID-19 outcome.
Khayat AS, et. al. (2020); PLoS One; 2020 ; 15 (12) 0243887. doi:10.1371/journal.pone.0243887
MESH:C000657245 SARS-CoV-2 infection|novel coronavirus pneumonia|2019 novel coronavirus diseases|Covid-19|COVID-19
MESH:D001102 viral infection|viral infections
MESH:D003643 mortality|deaths|death
MESH:D006333 heart failure
MESH:D006335 heart injury
MESH:D006973 hypertension
MESH:D007239 infection|infected
MESH:D011014 pneumonia
MESH:D015448 B-cell Leukemia
rs1029777004
G/A
CCR9 10803 3:45892581 1
 32658335
The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity.
Ovsyannikova IG, et. al. (2020); Immunol. Rev.; 2020 07 ; 296 (1) 205-219. doi:10.1111/imr.12897
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|SARS-CoV infection|coronavirus disease 2019|SARS-CoV-2 respiratory failure|novel coronavirus pneumonia|2019 novel coronavirus diseases|CoV-2 infection|COVID-NET|COVID-19|COVID|SARS coronavirus tightly|Novel Coronavirus Pneumonia|COVID19 infection|2019 novel coronavirus-infected pneumonia|Covid-19
MESH:C563602 MBL deficiency
MESH:C563662 invasive pneumococcal disease
MESH:D000857 olfactory loss
MESH:D001102 viral infection|virus infection|viral infections
MESH:D002303 decrease diseases
MESH:D003141 infectious disease|infectious diseases
MESH:D003428 nosocomial infection
MESH:D003643 mortality|Mortality|deaths|death
MESH:D003920 diabetes
MESH:D004487 edema
MESH:D005334 fever
MESH:D005767 gastrointestinal (GI) distress
MESH:D006313 sensorineural impairment
MESH:D006525 hepatitis virus infection
MESH:D006526 HCV-infected
MESH:D006973 hypertension
MESH:D007239 Infection|infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 renal injury
MESH:D008171 lung damage
MESH:D008231 lymphopenia
MESH:D008586 pneumococcal meningitis
MESH:D008589 meningococcal disease|invasive meningococcal disease
MESH:D009205 myocarditis
MESH:D009765 obesity
MESH:D011008 pneumococcal infection|pneumococcal pneumonia
MESH:D011014 pneumonia|lung inflammation
MESH:D011471 prostate cancer
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 deficiency and respiratory tract infection|respiratory tract infection|respiratory infection|respiratory co-infections|respiratory tract infections|upper respiratory tract infections
MESH:D012409 rubella
MESH:D014376 tuberculosis
MESH:D015047 zoonotic
MESH:D015658 HIV-1 infection|HIV infections
MESH:D016534 increase or decrease disease
MESH:D018352 coronavirus infections|coronavirus disease|respiratory syndrome coronavirus infection|seasonal coronavirus infections|SARS coronavirus infection|MERS infections|middle east respiratory syndrome coronavirus attachment|coronavirus infection|MERS|Middle East respiratory syndrome-coronavirus infection
MESH:D029424 chronic obstructive pulmonary disease
MESH:D030342 Genetic deficiency
MESH:D045169 severe acute respiratory syndrome|SARS infection
MESH:D055370 lung injury|alveolar damage
MESH:D055371 acute lung failure
MESH:D056486 hepatitis coronavirus|hepatitis
rs1030682178
A/G
DHX9 1660 1:182863184 1
 33329730
Whole Genome Identification of Potential G-Quadruplexes and Analysis of the G-Quadruplex Binding Domain for SARS-CoV-2.
Zhang R, et. al. (2020); Front Genet; 2020 ; 11 587829. doi:10.3389/fgene.2020.587829
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2-infected|Coronavirus disease 2019|coronavirus disease-2019|COVID-19
MESH:D003371 cough
MESH:D003643 death
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D006526 hepatitis C
MESH:D007239 infected|infection
MESH:D009369 cancer
MESH:D011014 pneumonia
MESH:D015658 HIV-1 (human immunodeficiency viruses type 1)
MESH:D018352 coronavirus disease|MERS|Middle East respiratory syndrome
MESH:D030361 papillomavirus G-quadruplexes
MESH:D051271 acute disease symptoms
rs1031034180
C/T
CCL5 6352 17:35872362 1
 25432065
Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression.
Narayanan K, et. al. (2015); Virus Res.; 2015 Apr 16; 20289-100. doi:10.1016/j.virusres.2014.11.019
MESH:C000657245 SARS-CoV infection|SARS-CoV and SARS-CoV-mt|SARS-CoV-mt-infected|CoV infection|SARS-CoV and SARS-CoV|CoV genera|SARS-CoV infectivity|SARS-CoV N antibody|chemokines Bat CoV|alpha-CoV, beta-CoV, gamma-CoV and delta-CoV|alpha-CoV and beta-CoV|SARS-CoV and MERS-CoV|SARS-CoV-infected|SARS-CoV and SARS-CoV-mt-infected|SARS-CoV-mt|SARS-CoV|CoV belonging|CoV|SARS-CoV- and SARS-CoV-mt-infected|CoV and beta-CoV
MESH:C536751 SCoV-WT
MESH:C538265 attenuated CoV
MESH:C564422 respiratory syndrome coronavirus ADP-ribose-1"-phosphate dephosphorylation
MESH:D001991 infectious bronchitis
MESH:D003333 HCoV-229E, HCoV-HKU1
MESH:D003924 HKU9-1, HKU9-2
MESH:D004751 enteric diseases
MESH:D007239 mock-infected|infection
MESH:D007674 embryonic kidney
MESH:D011014 pneumonia
MESH:D012128 respiratory distress syndrome
MESH:D012131 respiratory infection|viral respiratory disease|respiratory syndrome|respiratory syndrome CoV|respiratory disease
MESH:D012497 beta-CoV
MESH:D015430 SARS-CoV nsp1 gains access
MESH:D015658 virus infection
MESH:D016537 HKU9-1, belonging to beta-CoVB
MESH:D018352 Coronavirus|respiratory syndrome coronavirus infection|coronavirus respiratory infections|SARS-coronavirus causes disease|respiratory syndrome CoV and Middle East respiratory syndrome CoV|Middle East respiratory syndrome CoV|coronavirus MHV-A59|Coronavirus Nonstructural|respiratory syndrome coronavirus Nsp15|coronavirus infections|respiratory syndrome coronavirus 3a|SARS Coronavirus|respiratory syndrome coronavirus|coronavirus|SARS-coronavirus-host|MERS|rhinovirus and coronavirus
MESH:D018455 SARS-CoV S
MESH:D042822 CoV genome|SARS-CoV genome
MESH:D045169 Coronaviruses post-SARS
rs1031370622
C/T
MXRA8 54587 1:1354994 1
 33505806
Identification and molecular characterization of mutations in nucleocapsid phosphoprotein of SARS-CoV-2.
Azad GK, et. al. (2021); PeerJ; 2021 ; 9 10666. doi:10.7717/peerj.10666
MESH:C000657245 SARS-CoV infected|coronavirus disease 19|novel coronavirus pneumonia|COVID-19
MESH:D003643 mortality|deaths
MESH:D007239 infected
MESH:D009127 rigidity
MESH:D011014 pneumonia
MESH:D012128 respiratory distress
MESH:D012140 respiratory disease
rs1032525083
A/G
MAVS 57506 20:3865110 1
 30728254
Coronavirus Endoribonuclease Activity in Porcine Epidemic Diarrhea Virus Suppresses Type I and Type III Interferon Responses.
Deng X, et. al. (2019); J Virol. 2019 Apr 3;93(8). pii: JVI.02000-18. doi: 10.1128/JVI.02000-18. Print
MESH:C000657245 SARS coronavirus nonstructural|SARS-CoV-infected
MESH:C565627 diarrhea syndrome
MESH:D000795 alpha-CoV
MESH:D001102 virus-infected|intestinal viral infections|viral infections|virus infections|virus infection|viral infection|Viral infection|Viral disease
MESH:D001284 atrophy|villus atrophy
MESH:D003141 infectious diseases
MESH:D003643 mortality
MESH:D003967 Diarrhea Virus|diarrhoea syndrome|diarrhea coronavirus|diarrhea|diarrhea virus infects|acute diarrhea|diarrhea virus infection|Diarrhea Virus Suppresses Type I
MESH:D005767 gastrointestinal diseases
MESH:D006525 hepatitis virus nonstructural
MESH:D006526 hepatitis C virus
MESH:D006965 hyperplasia
MESH:D007239 icPEDV-EnUmt infected|EndoU-deficient PEDV infection|EnUmt-infected|WT-infected|infection|icPEDV-EnUmt infection|icPEDV-EnUmt-infected|Infection|icPEDV-EnUmt-infected PAMs|icPEDV-wt-infected PAMs|icPEDV-wt-infected|infections|PEDV-infected|infected
MESH:D011014 pneumonia
MESH:D012131 pandemic respiratory or gastrointestinal diseases
MESH:D012640 host fitness
MESH:D018352 Coronavirus|MERS|epidemic diarrhea coronavirus|CoV infection
rs10336
A/G,T
LOC101928809 101928809 4:76001835 2
 17540042
The association of RANTES polymorphism with severe acute respiratory syndrome in Hong Kong and Beijing Chinese.
Ng MW, et. al. (2007); BMC Infect. Dis.; 2007 Jun 01; 750
MESH:C000657245 SARS-CoV
MESH:D001102 viral infection|viral infections
MESH:D003141 infectious disease
MESH:D003643 deaths|death
MESH:D007239 infection
MESH:D007249 inflammation
MESH:D007251 influenza A virus infection
MESH:D008180 systemic lupus erythematosus
MESH:D008231 lymphopenia
MESH:D011014 lung inflammation
MESH:D012131 respiratory syndrome
MESH:D015658 HIV-1 disease|blocks HIV infection
MESH:D018352 Coronavirus|respiratory syndrome coronavirus infection|SARS coronavirus infection|SARS coronavirus infected
MESH:D019965 organ dysfunction
MESH:D020022
MESH:D045169 SARS|SARS infection
 33933633
Genetic polymorphisms as multi-biomarkers in severe acute respiratory syndrome (SARS) by coronavirus infection: A systematic review of candidate gene association studies.
Dos Santos ACM, et. al. (2021); Infect Genet Evol; 2021 Apr 29 104846. doi:10.1016/j.meegid.2021.104846
MESH:C000657245 covid-19|SARS-COV-2 infections|SARS-Cov infection|SARS-CoV infection|Covid-19|COVID-19
MESH:C566056 APCs
MESH:D000071069 hypoxic conditions
MESH:D000071074 neonatal sepsis and pneumonia
MESH:D000163 AIDS
MESH:D000783 vascular disease|cerebral vascular disease
MESH:D000860 hypoxemia|hypoxia
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001327 autoimmunity|autoimmune diseases
MESH:D002318 cardiovascular system
MESH:D002561 vascular dysfunction
MESH:D003092 colitis
MESH:D003093 ulcerative colitis
MESH:D003141 infectious diseases
MESH:D003324 coronary artery disease
MESH:D003371 dry cough
MESH:D003643 mortality|died|death
MESH:D003715 dengue disease
MESH:D003920 diabetes mellitus
MESH:D003924 Type 2 Diabetes Mellitus
MESH:D004417 dyspnea
MESH:D004487 alveolar edema
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D005355 fibrosis
MESH:D006470 hemorrhage
MESH:D006509 viral hepatitis B
MESH:D006526 HCV infection|cirrhosis, hepatitis C
MESH:D006800 HTLV-1 infection
MESH:D006973 hypertension
MESH:D007239 infections|infection|infected
MESH:D007249 inflammation|Inflammation
MESH:D007896 tegumentary leishmaniasis
MESH:D007918 leprosy
MESH:D008288 malaria
MESH:D009102 injury and organ failure
MESH:D009223 DM
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D011014 pneumonia
MESH:D011658 pulmonary fibrosis|fibrosis pulmonary
MESH:D012120 acute respiratory syndrome|acute respiratory syndrome coronavirus infection
MESH:D012128 adult respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory diseases
MESH:D012141 respiratory tract infections
MESH:D012772 septic shock
MESH:D014376 tuberculosis
MESH:D014397 pulmonary tuberculosis
MESH:D015440 lepromatous leprosy
MESH:D015658 HIV
MESH:D016638 critically ill
MESH:D018352 coronavirus infections|coronavirus disease|respiratory syndrome coronavirus infection|SARS coronavirus infection|Middle East respiratory syndrome|coronavirus infection|MERS|Coronavirus disease
MESH:D018805 sepsis
MESH:D019595 dengue hemorrhagic fever
MESH:D020521 stroke
MESH:D029424 chronic obstructive pulmonary disease|COPD
MESH:D045169 SARS|severe acute respiratory syndrome|SARS-COV infection|Severe acute respiratory syndrome
MESH:D050197 atherosclerosis
MESH:D051271 hypercoagulability and endotheliopathy symptoms
MESH:D051436 chronic kidney disease
MESH:D054990 idiopathic pulmonary fibrosis
MESH:D055370 lung injury
MESH:D056486 hepatitis
MESH:D059366 occupational asthma
MESH:D064420 toxicity
rs1033638
A/G
TARDBP 23435 1:11026660 1
 19405982
Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection.
Wang Y, et. al. (2009); BMC Infect. Dis.; 2009 May 01; 951. doi:10.1186/1471-2334-9-51
MESH:C000657245 SARS-CoV infection|SARS-CoV
MESH:C563602 MBL deficiency|Deficiency of MBL
MESH:C565360 MASP2 deficiency|deficiency of MASP2
MESH:D003141 infectious disease
MESH:D003920 diabetes mellitus
MESH:D006331 heart disease
MESH:D007153 deficiency
MESH:D007154 immunological disease
MESH:D007239 infection
MESH:D012131 respiratory disease syndrome|respiratory syndromecoronavirus infection|respiratory syndrome|Respiratory Syndrome
MESH:D018352 coronavirus|Coronavirus|respiratory syndrome coronavirus infection|SARS coronavirus infection
MESH:D020022
MESH:D045169 SARS|SARS coronavirus (SARS-CoV) infection|SARS-N|SARS infection
rs1036935762
C/T
TNF 7124 6:31575880 2
 32566803
Novel SARS-CoV-2/COVID-19: Origin, pathogenesis, genes and genetic variations, immune responses and phylogenetic analysis.
Junejo Y, et. al. (2020); Gene Rep; 2020 Sep ; 20 100752. doi:10.1016/j.genrep.2020.100752
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|novel coronavirus pneumoniainWuhan|Coronavirus disease 2019|novel coronavirus-infected pneumonia|CoV-2 infection|2019 novel coronavirus-infected pneumonia|Corona Virus Disease-19|coronavirus disease-2019|COVID-19|COVID
MESH:D000855 anorexia
MESH:D001102 viral infection|viral infections
MESH:D001424 bacterial infection
MESH:D001991 bronchitis
MESH:D002318 cardiovascular diseases
MESH:D003141 MiddleEastrespiratorysyndromecoronavirus disease
MESH:D003371 Cough|cough
MESH:D003643 deaths|death
MESH:D003967 diarrhea|Diarrhea
MESH:D004417 Shortness of breath|dyspnoea
MESH:D004679 encephalomyelitis
MESH:D005221 fatigue
MESH:D005334 Fever|fever
MESH:D005759 gastroenteritis virus TGEV
MESH:D006261 headache
MESH:D006331 cardiac injury
MESH:D006333 heart injury, kidney failure
MESH:D006469 hemoptysis
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D008171 Pulmonary disease
MESH:D008231 lymphopenia
MESH:D009102 multiple organ dysfunction
MESH:D009461 RAS dysfunction
MESH:D010534 peritonitis virus FCoV
MESH:D011014 Pneumonia|pneumonia
MESH:D012128 Acute respiratory distress syndrome|acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure
MESH:D012140 respiratory diseases|respiratory disease|Respiratory disease
MESH:D012141 respiratory tract infections|respiratory and intestinal infections|respiratory infections|respiratory tract infection|respiratory infectious disease|old corona infections|upper respiratory disease|upper respiratory tract
MESH:D012700 serositis
MESH:D012817 gastrointestinal symptoms
MESH:D012818 rhinorrhea
MESH:D014657 vasculitis
MESH:D014766 viremia
MESH:D014839 acute vomiting
MESH:D015047 zoonotic|Zoonotic
MESH:D017114 terminal acute liver failure
MESH:D018352 coronavirus disease|Sparrow coronavirus HKU17 HKU17 Sparrow Respiratory disease|Middle East respiratory syndrome coronavirus infection|CoV-HKU1 HCoV-HKU1 Human Pneumonia|Middle East respiratory syndrome|CoV infection
MESH:D045169 severe acute respiratory syndrome|Severe acute respiratory syndrome
MESH:D051271 cold symptoms
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D056486 liver enzyme abnormalities
MESH:D058186 kidney injury
OMIM:617025 lung injuries NC|leucopenia NC
 32658335
The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity.
Ovsyannikova IG, et. al. (2020); Immunol. Rev.; 2020 07 ; 296 (1) 205-219. doi:10.1111/imr.12897
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|SARS-CoV infection|coronavirus disease 2019|SARS-CoV-2 respiratory failure|novel coronavirus pneumonia|2019 novel coronavirus diseases|CoV-2 infection|COVID-NET|COVID-19|COVID|SARS coronavirus tightly|Novel Coronavirus Pneumonia|COVID19 infection|2019 novel coronavirus-infected pneumonia|Covid-19
MESH:C563602 MBL deficiency
MESH:C563662 invasive pneumococcal disease
MESH:D000857 olfactory loss
MESH:D001102 viral infection|virus infection|viral infections
MESH:D002303 decrease diseases
MESH:D003141 infectious disease|infectious diseases
MESH:D003428 nosocomial infection
MESH:D003643 mortality|Mortality|deaths|death
MESH:D003920 diabetes
MESH:D004487 edema
MESH:D005334 fever
MESH:D005767 gastrointestinal (GI) distress
MESH:D006313 sensorineural impairment
MESH:D006525 hepatitis virus infection
MESH:D006526 HCV-infected
MESH:D006973 hypertension
MESH:D007239 Infection|infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 renal injury
MESH:D008171 lung damage
MESH:D008231 lymphopenia
MESH:D008586 pneumococcal meningitis
MESH:D008589 meningococcal disease|invasive meningococcal disease
MESH:D009205 myocarditis
MESH:D009765 obesity
MESH:D011008 pneumococcal infection|pneumococcal pneumonia
MESH:D011014 pneumonia|lung inflammation
MESH:D011471 prostate cancer
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 deficiency and respiratory tract infection|respiratory tract infection|respiratory infection|respiratory co-infections|respiratory tract infections|upper respiratory tract infections
MESH:D012409 rubella
MESH:D014376 tuberculosis
MESH:D015047 zoonotic
MESH:D015658 HIV-1 infection|HIV infections
MESH:D016534 increase or decrease disease
MESH:D018352 coronavirus infections|coronavirus disease|respiratory syndrome coronavirus infection|seasonal coronavirus infections|SARS coronavirus infection|MERS infections|middle east respiratory syndrome coronavirus attachment|coronavirus infection|MERS|Middle East respiratory syndrome-coronavirus infection
MESH:D029424 chronic obstructive pulmonary disease
MESH:D030342 Genetic deficiency
MESH:D045169 severe acute respiratory syndrome|SARS infection
MESH:D055370 lung injury|alveolar damage
MESH:D055371 acute lung failure
MESH:D056486 hepatitis coronavirus|hepatitis
rs1038874256
G/A
SH2D3C 10044 9:127767207 1
 33586912
The COVID-19 epidemic in Madagascar: clinical description and laboratory results of the first wave, march-september 2020.
();
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|novel coronavirus-infected pneumonia|SARS-CoV-2 infected|TaqPath COVID-19|SARS-CoV-2-infected|SARS-CoV-2 fitness|Covid-19|COVID-19
MESH:D000370 anosmia and ageusia|ageusia
MESH:D000857 anosmia
MESH:D003371 Cough|aOR cough|cough
MESH:D003643 mortality|deaths
MESH:D005334 fever|Fever
MESH:D006261 headache|Headache
MESH:D007239 Infection|infection|infected
MESH:D011014 pneumonia|deadly pneumonia
MESH:D012140 respiratory illness|respiratory disease
MESH:D012141 respiratory infection|respiratory infections
MESH:D017827 Joseph
MESH:D018352 coronavirus disease
MESH:D018908 weakness
rs1039221273
A/C
LZTFL1 54585 3:45835626 1
 33811212
Genetic variability in COVID-19-related genes in the Brazilian population.
Secolin R, et. al. (2021); Hum Genome Var; 2021 Apr 02 ; 8 (1) 15. doi:10.1038/s41439-021-00146-w
MESH:C000657245 CoV-2 infection|COVID-19 pneumonia|SARS-CoV-2 infection|covid|Covid-19|coronavirus disease-2019|COVID-19
MESH:C566345 AFND
MESH:D001102 viral infections
MESH:D001281 AF
MESH:D003139 common epilepsies
MESH:D003141 infectious disease|infectious diseases
MESH:D003643 mortality|deaths|death
MESH:D004660 encephalitis
MESH:D006816 HD
MESH:D007239 infections|infection|infected
MESH:D008589 meningococcal disease|invasive meningococcal disease
MESH:D008661 Inborn errors of type I
MESH:D012131 Respiratory Failure|respiratory failure
MESH:D018352 respiratory syndrome coronavirus entry
rs1039418305
G/A
RTN2 6253 19:45489395 1
 33384909
Mutational spectra of SARS-CoV-2 isolated from animals.
Elaswad A, et. al. (2020); PeerJ; 2020 ; 8 10609. doi:10.7717/peerj.10609
MESH:C000656865 P P P L (2.7) P P P 199 P P P
MESH:C000657245 COVID-2019|coronavirus disease 2019|SARS-CoV-2 infection|novel coronavirus disease|SARS-CoV-2 infections|2019-nCoV infection|nCoV-2019|COVID-19
MESH:C536108 N N N T
MESH:C562719 TN
MESH:D000848 H H H Y (4.1) H H H|H H H H|H H H L|H H H H H
MESH:D001260 T T T T T NC|L 5195 T T T I (4.1) T T|229 T T T|T T T T
MESH:D003643 deaths
MESH:D007239 infected
MESH:D011014 pneumonia
MESH:D012140 respiratory disease
MESH:D015047 zoonotic|Zoonotic
MESH:D018352 Middle East respiratory syndrome
rs1040254981
A/G
PRSS57 400668 19:697355 1
 32742035
Variant analysis of SARS-CoV-2 genomes.
Koyama T, et. al. (2020); Bull World Health Organ; 2020 Jul 01 ; 98 (7) 495-504. doi:10.2471/BLT.20.253591
MESH:C000657245 novel infections|covid-19|SARS-CoV-2 pneumonia|coronavirus disease 2019|novel coronavirus pneumonia|COVID-19
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004417 shortness of breath
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D007239 infected
MESH:D009765 obesity
MESH:D011014 pneumonia
MESH:D012140 respiratory disease
MESH:D014786 loss
MESH:D015047 zoonotic
MESH:D016638 critically ill
MESH:D018352 Coronavirus disease
MESH:D055370 chronic lung disease
rs10409474
C/G
ELANE 1991 19:850733 1
 32835700
Variability in genes related to SARS-CoV-2 entry into host cells (ACE2, TMPRSS2, TMPRSS11A, ELANE, and CTSL) and its potential use in association studies.
Vargas-Alarcón G, et. al. (2020); Life Sci; 2020 Nov 01 ; 260 118313. doi:10.1016/j.lfs.2020.118313
MESH:C000657245 2019-nCoV infection|coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|Coronavirus disease 2019|COVID-19
MESH:C536438 cohen syndrome
MESH:C537592 congenital neutropenia
MESH:D000077277 esophageal squamous cell carcinoma
MESH:D001102 virus infections|viral infection|virus infection
MESH:D003550 cystic fibrosis
MESH:D003643 mortality
MESH:D003920 diabetes|diabetes mellitus
MESH:D004194 multifactorial diseases
MESH:D005355 fibrosis
MESH:D006333 heart failure
MESH:D006973 neurogenic hypertension|hypertension
MESH:D006984 hypertrophy
MESH:D007239 low infection|infections|infected|infection
MESH:D007249 inflammation
MESH:D009102 multiple organ dysfunction
MESH:D009503 neutropenia
MESH:D011014 pneumonia|pulmonary inflammation
MESH:D011658 pulmonary fibrosis
MESH:D012128 acute respiratory distress syndrome|lung injury and respiratory distress syndrome
MESH:D013927 thrombosis
MESH:D018352 Middle East respiratory syndrome coronavirus infection
MESH:D020257 cardiac remodeling
MESH:D029424 chronic obstructive pulmonary disease
MESH:D055370 lung injury|pulmonary injury
rs10413889 Affx-16278633
G/A
ELANE 1991 19:850299 1
 32835700
Variability in genes related to SARS-CoV-2 entry into host cells (ACE2, TMPRSS2, TMPRSS11A, ELANE, and CTSL) and its potential use in association studies.
Vargas-Alarcón G, et. al. (2020); Life Sci; 2020 Nov 01 ; 260 118313. doi:10.1016/j.lfs.2020.118313
MESH:C000657245 2019-nCoV infection|coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|Coronavirus disease 2019|COVID-19
MESH:C536438 cohen syndrome
MESH:C537592 congenital neutropenia
MESH:D000077277 esophageal squamous cell carcinoma
MESH:D001102 virus infections|viral infection|virus infection
MESH:D003550 cystic fibrosis
MESH:D003643 mortality
MESH:D003920 diabetes|diabetes mellitus
MESH:D004194 multifactorial diseases
MESH:D005355 fibrosis
MESH:D006333 heart failure
MESH:D006973 neurogenic hypertension|hypertension
MESH:D006984 hypertrophy
MESH:D007239 low infection|infections|infected|infection
MESH:D007249 inflammation
MESH:D009102 multiple organ dysfunction
MESH:D009503 neutropenia
MESH:D011014 pneumonia|pulmonary inflammation
MESH:D011658 pulmonary fibrosis
MESH:D012128 acute respiratory distress syndrome|lung injury and respiratory distress syndrome
MESH:D013927 thrombosis
MESH:D018352 Middle East respiratory syndrome coronavirus infection
MESH:D020257 cardiac remodeling
MESH:D029424 chronic obstructive pulmonary disease
MESH:D055370 lung injury|pulmonary injury
rs1041802302
C/G
FUZ 80199 19:49809494 1
 33127862
Molecular Architecture of Early Dissemination and Massive Second Wave of the SARS-CoV-2 Virus in a Major Metropolitan Area.
Long SW, et. al. (2020); mBio; 2020 Oct 30 ; 11 (6) . doi:10.1128/mBio.02707-20
MESH:C000657245 SARS-CoV-2 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|coronavirus-covid-19|CoV-2 infection|Covid-19|SARS-CoV-2 fitness|COVID-19
MESH:D000080345 XL
MESH:D001102 virus infection
MESH:D003141 Infectious Diseases
MESH:D003643 mortality|Mortality|deaths
MESH:D004342 Allergy
MESH:D005221 fatigue
MESH:D007239 infections|infected|infection
MESH:D007319 inability
MESH:D007710 Klebsiella pneumoniae
MESH:D011014 pneumonia
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 respiratory infections
MESH:D012640 fitness|virus fitness
MESH:D018352 CoV infection
rs1041981 Affx-28459465
C/A
LOC100287329 100287329 6:31573007 1
 21790707
Tumour necrosis factor gene polymorphism and disease prevalence.
Qidwai T, et. al. (2011); Scand. J. Immunol.; 2011 Dec; 74(6) 522-47. doi:10.1111/j.1365-3083.2011.02602.x
MESH:C000657245 SARS-Cov infection|SARS-CoV infection
MESH:C535516 MCL disease
MESH:C536382 vitreoretinopathy disease
MESH:C536439 endothelial dysfunction
MESH:C537392 type II deficiency
MESH:C537944 APPs
MESH:C538614 RCC|renal cell carcinoma
MESH:C562839 malignant pleural mesothelioma
MESH:C565292 atopic asthma|Atopic asthma
MESH:C567070 Mycobacterial diseases
MESH:D000080365 retinochoroiditis
MESH:D000230 pancreatic adenocarcinoma
MESH:D000275 depression|increased Beck Depression
MESH:D000544 Alzheimer's disease|AD disease|Alzheimer disease|AD
MESH:D000740 anaemia|malarial anemia
MESH:D001102 virus infection|Viral diseases
MESH:D001171 juvenile chronic arthritis
MESH:D001172 Rheumatoid arthritis|rheumatoid arthritis|RA
MESH:D001249 Asthma|asthma
MESH:D001327 Autoimmune diseases|autoimmune disease|autoimmune disorder|autoimmune diseases
MESH:D001424 Bacterial diseases|bacterial infection
MESH:D001523 irritation
MESH:D001528 BD
MESH:D001749 bladder cancer
MESH:D001862 osteoclastic bone
MESH:D001907 Mediterranean Spotted fever
MESH:D001943 invasive breast cancer|Breast Cancer|breast cancer|Breast cancer
MESH:D002051 Burkitt's lymphoma
MESH:D002318 Cardiovascular diseases|Cardiovascular disease|cardiovascular disease|cardiovascular diseases
MESH:D002538 brain arteriovenous malformation|Brain Arteriovenous Malformations
MESH:D002543 intracerebral haemorrhage|Spontaneous deep intracerebral hemorrhage|Intracerebral Hemorrhage|deep intracerebral haemorrhage|ICH|Spontaneous deep intracerebral haemorrhage|deep intracerebral hemorrhage
MESH:D002544 ischaemic strokes|Ischemic Strokes and Silent Brain Infarctions|ischaemic stroke|ischemic strokes and silent brain infarctions
MESH:D002598 chronic Chagas disease cardiomyopathy
MESH:D003093 ulcerative colitis
MESH:D003141 infectious disease|Infectious diseases|infectious diseases
MESH:D003424 Crohn's disease
MESH:D003550 cystic fibrosis|Cystic fibrosis
MESH:D003643 mortality|Mortality|deaths|died|death
MESH:D003704 dementia
MESH:D003715 Dengu infection
MESH:D003872 dermatitis
MESH:D003920 diabetes mellitus|diabetes|diabetic|Diabetes
MESH:D003922 insulin dependent diabetes mellitus|insulin-dependent diabetes mellitus|Type 1 diabetes mellitus
MESH:D003924 type II diabetic
MESH:D003928 Diabetic nephropathy|diabetic nephropathy
MESH:D004342 hypersensitivity
MESH:D004417 dyspnoea
MESH:D004421 psychiatric symptoms
MESH:D004715 endometriosis|Endometriosis
MESH:D004890 excess erythema|erythema|Excess hand erythema decreased
MESH:D004893 erythema nodosum|Uveitis and erythema nodosum in inflammatory bowel disease
MESH:D005221 fatigue
MESH:D005271 femoral head necrosis
MESH:D005334 fever
MESH:D005776 GD
MESH:D005935 Tumor Necrosis Factor alpha
MESH:D006105 granulomatous disease|multisystemic granulomatous disorder
MESH:D006111 Graves' disease
MESH:D006333 heart failure
MESH:D006470 Hemorrhage|haemorrhage
MESH:D006480 hemorrhagic fever
MESH:D006509 hepatitis B-infected|HBV infection|Hepatitis B virus (HBV) infection|chronic HBV infection|hepatitis B virus infection
MESH:D006526 hepatitis C Lotrich
MESH:D006528 hepatocellular carcinoma|hepatic cell carcinoma
MESH:D006816 HD
MESH:D007153 immunodeficiency
MESH:D007239 infection diseases|infections|infection|infected
MESH:D007249 inflammation|Inflammation
MESH:D007333 insulin resistance syndrome
MESH:D007592 joint damage|joint arthropathy
MESH:D007674 renal diseases
MESH:D007676 chronic renal failure
MESH:D007896 leishmaniasis|Leishmania braziliensis infection
MESH:D007918 leprosy
MESH:D007938 lymphoblastic leukaemia
MESH:D008010 lichen planus
MESH:D008105 primary biliary cirrhosis|biliary cirrhosis
MESH:D008175 lung cancer|lung cancers
MESH:D008180 systemic lupus erythematosus
MESH:D008228 non-Hodgkin's lymphoma|Non-Hodgkin's lymphoma
MESH:D008288 malaria|Malaria
MESH:D008589 meningococcal disease
MESH:D009069 mental rotation|Mental rotation
MESH:D009102 Sepsis-induced organ failure
MESH:D009103 multiple sclerosis|multiple sclerosis disease|Multiple sclerosis
MESH:D009202 cardiomyopathy|cardiomyopathies
MESH:D009203 MI Mellick|myocardial infarction
MESH:D009336 Tumour necrosis|tumour necrosis|Tumour Necrosis Factor|tumor necrosis
MESH:D009369 Cancer|cancer|cancers|tumour
MESH:D009437 Neuropathic pain|neuropathic pain
MESH:D009765 obesity
MESH:D009800 low disease
MESH:D010024 osteoporosis
MESH:D010031 Acute otitis|otitis
MESH:D010146 pain
MESH:D010190 pancreatic cancer
MESH:D010195 Pancreatitis|pancreatitis|Pancreatic|acute pancreatitis
MESH:D010272 parasitic disease
MESH:D011008 pneumococcal
MESH:D011471 Prostate cancer|prostate cancer
MESH:D011565 psoriasis|Psoriasis|psoriasis vulgaris
MESH:D012128 acute respiratory distress
MESH:D012480 Salmonella enterica infection
MESH:D012507 sarcoidosis|Sarcoidosis
MESH:D012598 sclerosis
MESH:D012640 fitness
MESH:D012772 Septic Shock|septic shock
MESH:D012829 silicosis
MESH:D012871 skin lesions
MESH:D013167 ankylosing spondylitis
MESH:D014352 trypanosomiasis|Trypanosomiasis
MESH:D014355 parasite Trypanosoma cruzi|Chagas disease
MESH:D014397 pulmonary tuberculosis|Pulmonary tuberculosis
MESH:D014435 Typhoid fever|typhoid fever
MESH:D014456 genital ulceration
MESH:D014605 uveitis
MESH:D014606 anterior uveitis|idiopathic acute anterior uveitis
MESH:D014947 trauma
MESH:D014949 blunt trauma
MESH:D014987 dryness
MESH:D015179 Colorectal
MESH:D015212 inflammatory bowel disease|IBD|Inflammatory bowel disease|bowel disease
MESH:D015440 lepromatous leprosy
MESH:D015441 tuberculoid leprosy
MESH:D015456 B cell acute lymphoblastic leukaemia
MESH:D015658 HIV|HIV-1 infection
MESH:D016136 Dermal diseases
MESH:D016773 cutaneous leishmaniasis
MESH:D016778 falciparum malaria|falciparum malarial infection
MESH:D016779 cerebral malaria
MESH:D017453 irritant hand dermatitis
MESH:D017565 pulmonary sarcoidosis
MESH:D018149 impaired glucose tolerance
MESH:D018630 proliferative vitreoretinopathy|vitreoretinopathy|Vitreoretinopathy
MESH:D018754 ventricular (LV) dysfunction
MESH:D018778 Puumala hantavirus infection
MESH:D018805 traumatic sepsis|sepsis
MESH:D019595 dengue haemorrhagic fever|dengue hemorrhagic fever
MESH:D019636 neurodegenerative diseases
MESH:D019694 chronic hepatitis B
MESH:D020141 haemostasis
MESH:D020300 intracranial haemorrhage
MESH:D020520 silent brain infarctions SBIs
MESH:D020521 stroke
MESH:D030342 lymphotoxin alfa genetic
MESH:D030361 HPV infection
MESH:D045169 SARS|SARS-infected|severe acute respiratory syndrome|Severe acute respiratory syndrome
MESH:D050197 atherosclerosis
MESH:D050723 fracture|fractures
MESH:D053842 TNFa microsatellite
MESH:D054144 Left ventricular diastolic dysfunction
MESH:D054198 acute lymphoblastic leukemia
MESH:D055665 fulminans purpura
MESH:D055732 pulmonary aspergillosis
MESH:D055744 invasive pulmonary aspergillosis
MESH:D055948 sarcopenia
MESH:D056587 multisystem inflammatory disorder
MESH:D058625 stage IV disease
OMIM:617237 Venezuelan 49
rs10419829
G/T
LOC107985305 107985305 19:44639551 2
 32637948
Genetic architecture of host proteins interacting with SARS-CoV-2.
Pietzner M, et. al. (2020); bioRxiv; 2020 Jul 01 . doi:10.1101/2020.07.01.182709
MESH:C000657245 CoV-2 infection|SARS-Cov-2 infection|covid-19|SARS-CoV-2 infection|coronavirus disease 2019|Covid-19|COVID-19
MESH:D000783 arterial vascular disease
MESH:D000795 Fabry's disease
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma|asthma-GRS
MESH:D001778 coagulopathy
MESH:D002318 Cardiovascular Disease
MESH:D003139 Common Complex Disease
MESH:D003324 coronary artery disease|coronary heart disease|Coronary Disease
MESH:D003643 mortality|Mortality
MESH:D003920 diabetes mellitus|diabetes
MESH:D003924 Type 2 Diabetes|type 2 diabetes
MESH:D004342 allergic disease
MESH:D007239 infected
MESH:D007249 inflammation
MESH:D007319 inability
MESH:D009336 necrotic
MESH:D009800 deterioration
MESH:D010300 Parkinson's disease
MESH:D011618 psychotic disorder
MESH:D011655 pulmonary embolism
MESH:D012131 respiratory failure
MESH:D013924 phlebitis and thrombophlebitis
MESH:D014842 van Willebrand
MESH:D018352 Coronavirus disease
MESH:D019851 hypercoagulation
MESH:D020246 venous thrombosis
MESH:D029424 chronic obstructive pulmonary disease
MESH:D054556 venous thromboembolism
 33328453
Genetic architecture of host proteins involved in SARS-CoV-2 infection.
Pietzner M, et. al. (2020); Nat Commun; 2020 12 16 ; 11 (1) 6397. doi:10.1038/s41467-020-19996-z
MESH:C000657245 CoV-2 infection|covid-19|SARS-CoV-2 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|Covid-19|COVID-19
MESH:D000783 arterial vascular disease
MESH:D000795 Fabry's disease
MESH:D001172 rheumatoid arthritis|RA
MESH:D001249 asthma|asthma-GRS
MESH:D001778 coagulopathy
MESH:D002318 cardiovascular traits|Cardiovascular disease|cardiovascular disease
MESH:D003324 coronary artery disease|coronary disease|coronary heart disease
MESH:D003643 mortality|death
MESH:D003920 diabetes|diabetes mellitus
MESH:D004342 allergic disease
MESH:D007105 complex disease
MESH:D007239 Infection|infected|infection
MESH:D007249 inflammation
MESH:D007319 inability
MESH:D009336 necrotic
MESH:D009800 deterioration
MESH:D010300 Parkinson's disease
MESH:D011618 psychotic disorder
MESH:D011655 pulmonary embolism
MESH:D012131 respiratory failure
MESH:D013924 phlebitis and thrombophlebitis
MESH:D014842 van Willebrand
MESH:D016638 critical illness
MESH:D018352 Coronavirus disease
MESH:D019851 hypercoagulation|Hypercoagulation
MESH:D020246 venous thrombosis
MESH:D029424 chronic obstructive pulmonary disease
MESH:D054556 venous thromboembolism
rs1042364674
T/A,C
SPECC1 92521 17:20024470 1
 33236025

();
MESH:C000657245 covid-19|COVID-2019|Coronavirus Disease 2019|Coronavirus disease 2019|SARS-CoV-2 infections|SARS-CoV-2 Infection|COVID-19
MESH:D000079225 stress
MESH:D001281 AF
MESH:D003643 death
MESH:D007239 infection|infected
MESH:D009369 cancer
MESH:D011014 Pneumonia
MESH:D012141 respiratory infection
MESH:D052456 HIGH
rs1042443197
C/A,T
TNFAIP3 7128 6:137878947 1
 33804556
SARS-CoV-2 Variant of Concern 202012/01 Has about Twofold Replicative Advantage and Acquires Concerning Mutations.
Grabowski F, et. al. (2021); Viruses; 2021 Mar 01 ; 13 (3) . doi:10.3390/v13030392
MESH:C000657245 SARS-CoV-2 infection|COVID-19
MESH:D003643 deaths
MESH:D007239 infections|infection|infected
MESH:D012640 fits
rs1042522
G/C,T
TP53 7157 17:7676154 1
 32822430
Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: A meta-analysis of 6320 patients.
Elshazli RM, et. al. (2020); PLoS ONE; 2020 ; 15 (8) 0238160. doi:10.1371/journal.pone.0238160
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|COVID19|novel coronavirus pneumonia|2019 Novel Coronavirus Disease|Coronavirus disease- 2019|CoV-2 infected|Coronavirus Disease 2019|COVID-19|COVID|2019 Novel Coronavirus-Infected Pneumonia|SARS-CoV-2 pneumonia|Coronavirus disease 2019|Novel Coronavirus Infections|2019 novel coronavirus disease|Coronavirus Disease 2019 Pneumonia|COVID-19 Pneumonia|2019-nCoV pneumonia
MESH:C537501 SMD
MESH:D002908 chronic diseases
MESH:D003371 cough
MESH:D003643 Died|mortality|Mortality|Death|died|death
MESH:D004417 shortness of breath|dyspnea and pneumonia
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D006331 Cardiac Injury
MESH:D007239 Infection|Infected|infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 Kidney disease
MESH:D007964 leukocytosis
MESH:D007970 leukopenia
MESH:D008231 lymphopenia
MESH:D011014 Pneumonia|pneumonias|pneumonia
MESH:D012128 Acute Respiratory Distress Syndrome|ARDS
MESH:D013921 Thrombocytopenia|thrombocytopenia
MESH:D015047 zoonotic
MESH:D015179 colorectal cancer
MESH:D016638 Critically Ill|critically ill
MESH:D018352 Coronavirus Diseases|coronavirus infection|MERS|Middle East Respiratory Syndrome|Coronavirus (MERS-CoV) infection
MESH:D025861 Abnormal coagulation
MESH:D045169 severe acute respiratory syndrome
rs1042580 Affx-16513075
T/C
THBD 7056 20:23046984 1
 33845193
Genetic justification of severe COVID-19 using a rigorous algorithm.
Gavriilaki E, et. al. (2021); Clin Immunol; 2021 Apr 09 108726. doi:10.1016/j.clim.2021.108726
MESH:C000657245 covid-19|COVID-19 pneumonia|SARS-CoV-2 infection|Coronavirus disease-19|COVID19|CoV-2 infection|coronavirus disease-19|COVID-19 immunothrombosis|Covid-19|COVID-19
MESH:C531844 von Willebrand factor anchored
MESH:C535882 Johnson
MESH:C536439 endothelial dysfunction
MESH:C537005 Complement C3 vs C5 inhibition
MESH:C562875 complement factor H
MESH:C563256 CFD
MESH:C565169 complement C3|C3 blockade
MESH:D000743 microangiopathic hemolytic anemia
MESH:D000783 TMA
MESH:D001102 viral infection
MESH:D001327 autoimmune diseases
MESH:D001778 coagulation dysfunction
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D003924 type 2 diabetes mellitus
MESH:D004342 hypersensitivity
MESH:D004487 Lung Edema
MESH:D006009 AMD
MESH:D006086 graft-versus-host disease
MESH:D006461 hemolysis
MESH:D006463 hemolytic-uremic syndrome|hemolytic uremic syndrome
MESH:D007153 deficiency
MESH:D007239 infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 C3 glomerulopathy
MESH:D008171 lung damage
MESH:D008180 lupus
MESH:D008661 Inborn errors of type I
MESH:D009765 obesity
MESH:D011697 thrombotic thrombocytopenic purpura
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure
MESH:D013921 thrombocytopenia
MESH:D013927 thrombosis
MESH:D014657 vasculitis
MESH:D014842 von Willebrand
MESH:D016638 critical illness|critically ill
MESH:D016736 catastrophic antiphospholipid antibody syndrome
MESH:D016884 APS
MESH:D017566 microvascular injury
MESH:D019965 organ damage
MESH:D034721 systemic disease
MESH:D051437 renal failure
MESH:D055370 lung injury
MESH:D057049 thrombotic microangiopathies|thrombotic microangiopathy
MESH:D057129 endothelial dysfunction syndromes
MESH:D057772 vascular injury
MESH:D065766 H-atypical hemolytic uremic syndrome|atypical hemolytic uremic syndrome
rs1042658
C/G,T
CSF3 1440 17:40017649 1
 33246355
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.
Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
MESH:C000657245 coronavirus 2 infection|SARS-CoV-2 infection|coronavirus disease 2019|coronavirus (2019-nCoV) infections|COVID-19
MESH:D000077192 lung adenocarcinoma
MESH:D001281 atrial fibrillation
MESH:D001943 Breast cancer
MESH:D002318 cardiovascular diseases
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004487 oedema
MESH:D004646 emphysema
MESH:D005334 fever
MESH:D007239 infection|infected
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 lung damage
MESH:D008175 lung cancer
MESH:D009102 multiple organ failure|sepsis and organ failure
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012818 respiratory and gastrointestinal infections
MESH:D018352 coronavirus disease
MESH:D055370 lung injury|chronic lung disease
MESH:D055371 acute lung injury
MESH:D063806 muscle soreness
rs1042713 Affx-25828625
G/A
ADRB2 154 5:148826877 2
 32676577
A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19.
Zhou Y, et. al. (2020); ChemRxiv; 2020 Jul 02 . doi:10.26434/chemrxiv.12579137.v1
MESH:C000657245 SARS-CoV-2 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-1 infected|asthma-COVID-19|common coronavirus disease-19|novel coronavirus pneumonia|CoV-2 infection|SARS-CoV-2 infected|Coronavirus Disease 2019|SARS-CoV-2-infected|Covid-19|COVID-19|2019 Novel Coronavirus-Infected Pneumonia
MESH:D000079225 stress
MESH:D001102 Virus Infection|viral infection|virus infection|viral infections
MESH:D001145 arrhythmia
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma|Asthma|bronchial asthma
MESH:D001289 attention-deficit/hyperactivity disorder
MESH:D001321 Autism
MESH:D001424 bacterial infections
MESH:D001988 Bronchiolitis
MESH:D001997 Bronchopulmonary Dysplasia
MESH:D002318 cardiovascular or cerebrovascular disease|cardiovascular disease|cardiovascular diseases|Cardiovascular Disease
MESH:D003093 Ulcerative Colitis
MESH:D003141 infectious diseases|disease-disease
MESH:D003324 coronary artery disease|Coronary artery
MESH:D003398 CRS
MESH:D003424 Crohn's disease|Crohn's Disease Lesions
MESH:D003643 mortality|Mortality|deaths|death
MESH:D003920 diabetes mellitus|diabetes|Diabetes
MESH:D003928 diabetic nephropathy
MESH:D003967 diarrhea|Diarrhea
MESH:D004417 dyspnea
MESH:D005767 gastrointestinal diseases
MESH:D006323 Cardiac Arrest|cardiac arrest
MESH:D006327 heart block
MESH:D006331 heart disease
MESH:D006333 congestive heart failure|heart failure
MESH:D006973 Hypertension|hypertension
MESH:D007239 Infection|Infections|infection|infected
MESH:D007249 inflammation
MESH:D008171 pulmonary diseases|Pulmonary diseases|lung disease
MESH:D008659 metabolic diseases
MESH:D009202 myocardial injury
MESH:D009369 Cancer|malignancy|cancer
MESH:D009765 obese
MESH:D010051 ovarian cancer
MESH:D011014 Pneumonia|pneumonia|pulmonary inflammation
MESH:D011658 pulmonary fibrosis
MESH:D012128 proteins of respiratory distress syndrome|respiratory distress syndrome|acute respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012772 septic shock
MESH:D015212 inflammatory bowel disease|Inflammatory Bowel Disease|IBD|Inflammatory bowel disease
MESH:D015746 abdominal pain
MESH:D016638 Critically Ill|critically ill
MESH:D018352 MERS-CoV infected|Middle East respiratory syndrome coronavirus infection
MESH:D018805 sepsis
MESH:D020271 neurological diseases
MESH:D020521 stroke
MESH:D028361 mitochondrial damage in septic cardiomyopathy
MESH:D029424 chronic obstructive pulmonary disease|COPD
MESH:D030342 genetic disorders|Mendelian disease
MESH:D035583 orphan disease|Orphan disease
MESH:D044882 glucose metabolism
MESH:D045169 Severe Disease|Severe Acute Respiratory Syndrome
MESH:D051436 chronic kidney disease
MESH:D055370 lung injury
 33156843
A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19.
Zhou Y, et. al. (2020); PLoS Biol; 2020 Nov 06 ; 18 (11) 3000970. doi:10.1371/journal.pbio.3000970
MESH:C000657245 SARS-CoV-2 pneumonia|covid-19|coronavirus disease 2019|SARS-CoV-2 infection|2019 novel Coronavirus-infected pneumonia|asthma-COVID-19|COVID19|novel coronavirus pneumonia|CoV-2 infection|SARS-CoV-2 infected|Coronavirus Disease 2019|SARS-CoV-1-infected|SARS-CoV-2-infected|Covid-19|COVID-19
MESH:D000079225 stress
MESH:D000783 vascular damage
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001145 arrhythmia
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma|bronchial asthma
MESH:D001289 attention-deficit/hyperactivity disorder
MESH:D001321 autism
MESH:D001424 bacterial infections
MESH:D001988 bronchiolitis
MESH:D001997 bronchopulmonary dysplasia
MESH:D002318 cardiovascular or cerebrovascular disease|cardiovascular system|cardiovascular disease|cardiovascular diseases
MESH:D002547 cerebral palsy
MESH:D002908 chronic disease
MESH:D003093 ulcerative colitis
MESH:D003141 infectious diseases|disease-disease
MESH:D003324 coronary artery disease|Coronary artery disease
MESH:D003398 CRS
MESH:D003424 Crohn disease|Crohn's disease
MESH:D003643 mortality|deaths|death
MESH:D003920 diabetes mellitus|diabetes|Diabetes
MESH:D003928 diabetic nephropathy
MESH:D003967 diarrhea|Diarrhea
MESH:D004417 dyspnea
MESH:D004646 emphysema
MESH:D005598 Tomsich Pathology
MESH:D005767 gastrointestinal diseases
MESH:D006323 cardiac arrest
MESH:D006327 heart block
MESH:D006333 congestive heart failure|heart failure
MESH:D006948 hyperactivity disorder
MESH:D006973 Hypertension|hypertension
MESH:D007239 infection|infected
MESH:D007249 inflammation
MESH:D008171 pulmonary diseases|Pulmonary diseases|lung disease
MESH:D008659 metabolic diseases
MESH:D009202 myocardial injury
MESH:D009369 Cancer|malignancy|malignant cancer|cancer|cancers
MESH:D009765 obese
MESH:D010051 ovarian cancer
MESH:D011014 pneumonia|pulmonary inflammation
MESH:D011658 pulmonary fibrosis
MESH:D012128 proteins of respiratory distress syndrome|Respiratory distress syndrome|respiratory distress syndrome|acute respiratory distress syndrome|respiratory distress syndroms
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012772 septic shock
MESH:D015179 colorectal cancer
MESH:D015212 inflammatory bowel disease|IBD|Inflammatory bowel disease|inflammatory bowel diseases
MESH:D015746 abdominal pain
MESH:D016638 critically ill|critically Ill
MESH:D018352 Middle East respiratory syndrome coronavirus infection|CoV-infected
MESH:D018805 sepsis
MESH:D020271 neurological diseases
MESH:D020521 stroke
MESH:D028361 mitochondrial damage in septic cardiomyopathy
MESH:D029424 chronic obstructive pulmonary disease|COPD
MESH:D030342 genetic dysfunction|genetic disorders|Mendelian disease
MESH:D035583 rare diseases|orphan disease
MESH:D044882 glucose metabolism
MESH:D051436 chronic kidney disease
MESH:D055370 lung injury
rs1042714 Affx-291210177
G/C,T
ADRB2 154 5:148826910 2
 32676577
A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19.
Zhou Y, et. al. (2020); ChemRxiv; 2020 Jul 02 . doi:10.26434/chemrxiv.12579137.v1
MESH:C000657245 SARS-CoV-2 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-1 infected|asthma-COVID-19|common coronavirus disease-19|novel coronavirus pneumonia|CoV-2 infection|SARS-CoV-2 infected|Coronavirus Disease 2019|SARS-CoV-2-infected|Covid-19|COVID-19|2019 Novel Coronavirus-Infected Pneumonia
MESH:D000079225 stress
MESH:D001102 Virus Infection|viral infection|virus infection|viral infections
MESH:D001145 arrhythmia
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma|Asthma|bronchial asthma
MESH:D001289 attention-deficit/hyperactivity disorder
MESH:D001321 Autism
MESH:D001424 bacterial infections
MESH:D001988 Bronchiolitis
MESH:D001997 Bronchopulmonary Dysplasia
MESH:D002318 cardiovascular or cerebrovascular disease|cardiovascular disease|cardiovascular diseases|Cardiovascular Disease
MESH:D003093 Ulcerative Colitis
MESH:D003141 infectious diseases|disease-disease
MESH:D003324 coronary artery disease|Coronary artery
MESH:D003398 CRS
MESH:D003424 Crohn's disease|Crohn's Disease Lesions
MESH:D003643 mortality|Mortality|deaths|death
MESH:D003920 diabetes mellitus|diabetes|Diabetes
MESH:D003928 diabetic nephropathy
MESH:D003967 diarrhea|Diarrhea
MESH:D004417 dyspnea
MESH:D005767 gastrointestinal diseases
MESH:D006323 Cardiac Arrest|cardiac arrest
MESH:D006327 heart block
MESH:D006331 heart disease
MESH:D006333 congestive heart failure|heart failure
MESH:D006973 Hypertension|hypertension
MESH:D007239 Infection|Infections|infection|infected
MESH:D007249 inflammation
MESH:D008171 pulmonary diseases|Pulmonary diseases|lung disease
MESH:D008659 metabolic diseases
MESH:D009202 myocardial injury
MESH:D009369 Cancer|malignancy|cancer
MESH:D009765 obese
MESH:D010051 ovarian cancer
MESH:D011014 Pneumonia|pneumonia|pulmonary inflammation
MESH:D011658 pulmonary fibrosis
MESH:D012128 proteins of respiratory distress syndrome|respiratory distress syndrome|acute respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012772 septic shock
MESH:D015212 inflammatory bowel disease|Inflammatory Bowel Disease|IBD|Inflammatory bowel disease
MESH:D015746 abdominal pain
MESH:D016638 Critically Ill|critically ill
MESH:D018352 MERS-CoV infected|Middle East respiratory syndrome coronavirus infection
MESH:D018805 sepsis
MESH:D020271 neurological diseases
MESH:D020521 stroke
MESH:D028361 mitochondrial damage in septic cardiomyopathy
MESH:D029424 chronic obstructive pulmonary disease|COPD
MESH:D030342 genetic disorders|Mendelian disease
MESH:D035583 orphan disease|Orphan disease
MESH:D044882 glucose metabolism
MESH:D045169 Severe Disease|Severe Acute Respiratory Syndrome
MESH:D051436 chronic kidney disease
MESH:D055370 lung injury
 33156843
A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19.
Zhou Y, et. al. (2020); PLoS Biol; 2020 Nov 06 ; 18 (11) 3000970. doi:10.1371/journal.pbio.3000970
MESH:C000657245 SARS-CoV-2 pneumonia|covid-19|coronavirus disease 2019|SARS-CoV-2 infection|2019 novel Coronavirus-infected pneumonia|asthma-COVID-19|COVID19|novel coronavirus pneumonia|CoV-2 infection|SARS-CoV-2 infected|Coronavirus Disease 2019|SARS-CoV-1-infected|SARS-CoV-2-infected|Covid-19|COVID-19
MESH:D000079225 stress
MESH:D000783 vascular damage
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001145 arrhythmia
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma|bronchial asthma
MESH:D001289 attention-deficit/hyperactivity disorder
MESH:D001321 autism
MESH:D001424 bacterial infections
MESH:D001988 bronchiolitis
MESH:D001997 bronchopulmonary dysplasia
MESH:D002318 cardiovascular or cerebrovascular disease|cardiovascular system|cardiovascular disease|cardiovascular diseases
MESH:D002547 cerebral palsy
MESH:D002908 chronic disease
MESH:D003093 ulcerative colitis
MESH:D003141 infectious diseases|disease-disease
MESH:D003324 coronary artery disease|Coronary artery disease
MESH:D003398 CRS
MESH:D003424 Crohn disease|Crohn's disease
MESH:D003643 mortality|deaths|death
MESH:D003920 diabetes mellitus|diabetes|Diabetes
MESH:D003928 diabetic nephropathy
MESH:D003967 diarrhea|Diarrhea
MESH:D004417 dyspnea
MESH:D004646 emphysema
MESH:D005598 Tomsich Pathology
MESH:D005767 gastrointestinal diseases
MESH:D006323 cardiac arrest
MESH:D006327 heart block
MESH:D006333 congestive heart failure|heart failure
MESH:D006948 hyperactivity disorder
MESH:D006973 Hypertension|hypertension
MESH:D007239 infection|infected
MESH:D007249 inflammation
MESH:D008171 pulmonary diseases|Pulmonary diseases|lung disease
MESH:D008659 metabolic diseases
MESH:D009202 myocardial injury
MESH:D009369 Cancer|malignancy|malignant cancer|cancer|cancers
MESH:D009765 obese
MESH:D010051 ovarian cancer
MESH:D011014 pneumonia|pulmonary inflammation
MESH:D011658 pulmonary fibrosis
MESH:D012128 proteins of respiratory distress syndrome|Respiratory distress syndrome|respiratory distress syndrome|acute respiratory distress syndrome|respiratory distress syndroms
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012772 septic shock
MESH:D015179 colorectal cancer
MESH:D015212 inflammatory bowel disease|IBD|Inflammatory bowel disease|inflammatory bowel diseases
MESH:D015746 abdominal pain
MESH:D016638 critically ill|critically Ill
MESH:D018352 Middle East respiratory syndrome coronavirus infection|CoV-infected
MESH:D018805 sepsis
MESH:D020271 neurological diseases
MESH:D020521 stroke
MESH:D028361 mitochondrial damage in septic cardiomyopathy
MESH:D029424 chronic obstructive pulmonary disease|COPD
MESH:D030342 genetic dysfunction|genetic disorders|Mendelian disease
MESH:D035583 rare diseases|orphan disease
MESH:D044882 glucose metabolism
MESH:D051436 chronic kidney disease
MESH:D055370 lung injury
rs1042838
C/A,G
PGR 5241 11:101062681 1
 33390179
Alu retrotransposons and COVID-19 susceptibility and morbidity.
Li M, et. al. (2021); Hum Genomics; 2021 Jan 04 ; 15 (1) 2. doi:10.1186/s40246-020-00299-9
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|Coronavirus disease 2019|covid|COVID-19
MESH:C536439 endothelial dysfunction
MESH:C564969 multi-organ damage and multi-system dysfunction
MESH:D000080343 Spiridonova MG
MESH:D000783 TMA
MESH:D001102 viral infection|viral infections
MESH:D001424 bacterial infection
MESH:D001778 blood coagulation|insufficient coagulation
MESH:D002318 Cardiovascular diseases|Cardiovascular complications|cardiovascular complications|cardiovascular conditions|cardiovascular disease|cardiovascular accidents|cardiovascular diseases
MESH:D002544 ischemic stroke|Ischemic stroke
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003324 coronary atherosclerosis|atherosclerotic coronary artery disease|coronary artery disease|coronary artery atherosclerosis
MESH:D003643 mortality|deaths
MESH:D003920 diabetes|diabetic normotensive
MESH:D004342 Inflamm Allergy Drug
MESH:D006470 bleeding|bleeding disorders|bleeding disorder
MESH:D006973 hypertension
MESH:D007153 immunodeficiency virus
MESH:D007239 infections|HEV infection|infected|infection
MESH:D007249 inflammation
MESH:D007674 renal diseases
MESH:D009196 myeloproliferative disorder
MESH:D009203 Myocardial infarction|myocardial infarction
MESH:D009461 fibrinolysis dysfunction
MESH:D010051 Ovarian carcinoma
MESH:D011014 Pneumonia|pneumonia
MESH:D011655 pulmonary embolism|Pulmonary embolism
MESH:D012128 Acute respiratory distress syndrome|acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 respiratory infections
MESH:D012769 shock
MESH:D013923 thromboembolism and atherosclerosis|thromboembolism
MESH:D013927 thrombotic syndrome|thrombosis
MESH:D014766 viremia
MESH:D015047 zoonotic infectious disease
MESH:D016751 Hepatitis E virus|acute hepatitis E
MESH:D016920 bacterial osteomyelitis
MESH:D018352 coronavirus infection
MESH:D019851 Thromboinflammation and the hypercoagulability|thromboinflammation and hypercoagulative
MESH:D020246 venous thrombosis|Venous thrombosis
MESH:D020521 stroke
MESH:D031368 SINEs
MESH:D054556 venous thromboembolism|VTE
MESH:D055370 lung injury
MESH:D057049 thrombotic microangiopathy
rs1042839
G/A
PGR 5241 11:101051471 1
 33390179
Alu retrotransposons and COVID-19 susceptibility and morbidity.
Li M, et. al. (2021); Hum Genomics; 2021 Jan 04 ; 15 (1) 2. doi:10.1186/s40246-020-00299-9
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|Coronavirus disease 2019|covid|COVID-19
MESH:C536439 endothelial dysfunction
MESH:C564969 multi-organ damage and multi-system dysfunction
MESH:D000080343 Spiridonova MG
MESH:D000783 TMA
MESH:D001102 viral infection|viral infections
MESH:D001424 bacterial infection
MESH:D001778 blood coagulation|insufficient coagulation
MESH:D002318 Cardiovascular diseases|Cardiovascular complications|cardiovascular complications|cardiovascular conditions|cardiovascular disease|cardiovascular accidents|cardiovascular diseases
MESH:D002544 ischemic stroke|Ischemic stroke
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003324 coronary atherosclerosis|atherosclerotic coronary artery disease|coronary artery disease|coronary artery atherosclerosis
MESH:D003643 mortality|deaths
MESH:D003920 diabetes|diabetic normotensive
MESH:D004342 Inflamm Allergy Drug
MESH:D006470 bleeding|bleeding disorders|bleeding disorder
MESH:D006973 hypertension
MESH:D007153 immunodeficiency virus
MESH:D007239 infections|HEV infection|infected|infection
MESH:D007249 inflammation
MESH:D007674 renal diseases
MESH:D009196 myeloproliferative disorder
MESH:D009203 Myocardial infarction|myocardial infarction
MESH:D009461 fibrinolysis dysfunction
MESH:D010051 Ovarian carcinoma
MESH:D011014 Pneumonia|pneumonia
MESH:D011655 pulmonary embolism|Pulmonary embolism
MESH:D012128 Acute respiratory distress syndrome|acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 respiratory infections
MESH:D012769 shock
MESH:D013923 thromboembolism and atherosclerosis|thromboembolism
MESH:D013927 thrombotic syndrome|thrombosis
MESH:D014766 viremia
MESH:D015047 zoonotic infectious disease
MESH:D016751 Hepatitis E virus|acute hepatitis E
MESH:D016920 bacterial osteomyelitis
MESH:D018352 coronavirus infection
MESH:D019851 Thromboinflammation and the hypercoagulability|thromboinflammation and hypercoagulative
MESH:D020246 venous thrombosis|Venous thrombosis
MESH:D020521 stroke
MESH:D031368 SINEs
MESH:D054556 venous thromboembolism|VTE
MESH:D055370 lung injury
MESH:D057049 thrombotic microangiopathy
rs10434 Affx-28656591
A/G
VEGFA 7422 6:43785475 1
 33246355
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.
Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
MESH:C000657245 coronavirus 2 infection|SARS-CoV-2 infection|coronavirus disease 2019|coronavirus (2019-nCoV) infections|COVID-19
MESH:D000077192 lung adenocarcinoma
MESH:D001281 atrial fibrillation
MESH:D001943 Breast cancer
MESH:D002318 cardiovascular diseases
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004487 oedema
MESH:D004646 emphysema
MESH:D005334 fever
MESH:D007239 infection|infected
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 lung damage
MESH:D008175 lung cancer
MESH:D009102 multiple organ failure|sepsis and organ failure
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012818 respiratory and gastrointestinal infections
MESH:D018352 coronavirus disease
MESH:D055370 lung injury|chronic lung disease
MESH:D055371 acute lung injury
MESH:D063806 muscle soreness
rs1044870110
G/A,T
SPECC1 92521 17:20260223 2
 32742035
Variant analysis of SARS-CoV-2 genomes.
Koyama T, et. al. (2020); Bull World Health Organ; 2020 Jul 01 ; 98 (7) 495-504. doi:10.2471/BLT.20.253591
MESH:C000657245 novel infections|covid-19|SARS-CoV-2 pneumonia|coronavirus disease 2019|novel coronavirus pneumonia|COVID-19
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004417 shortness of breath
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D007239 infected
MESH:D009765 obesity
MESH:D011014 pneumonia
MESH:D012140 respiratory disease
MESH:D014786 loss
MESH:D015047 zoonotic
MESH:D016638 critically ill
MESH:D018352 Coronavirus disease
MESH:D055370 chronic lung disease
 33170902
Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geo-distribution and a rich genetic variations of hotspots mutations.
Laamarti M, et. al. (2020); PLoS One; 2020 ; 15 (11) 0240345. doi:10.1371/journal.pone.0240345
MESH:C000657245 covid-19|SARS-CoV-2 infection|COVID 2019|COVID-19
MESH:C536677 SVD
MESH:D001102 viral infection
MESH:D003643 mortality|deaths
MESH:D007239 infections
MESH:D012140 respiratory disease
MESH:D018352 Respiratory Syndrome Coronavirus Infection|Coronavirus disease
rs1044890948
T/C
ACE2 59272 X:15508366 1
 33127862
Molecular Architecture of Early Dissemination and Massive Second Wave of the SARS-CoV-2 Virus in a Major Metropolitan Area.
Long SW, et. al. (2020); mBio; 2020 Oct 30 ; 11 (6) . doi:10.1128/mBio.02707-20
MESH:C000657245 SARS-CoV-2 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|coronavirus-covid-19|CoV-2 infection|Covid-19|SARS-CoV-2 fitness|COVID-19
MESH:D000080345 XL
MESH:D001102 virus infection
MESH:D003141 Infectious Diseases
MESH:D003643 mortality|Mortality|deaths
MESH:D004342 Allergy
MESH:D005221 fatigue
MESH:D007239 infections|infected|infection
MESH:D007319 inability
MESH:D007710 Klebsiella pneumoniae
MESH:D011014 pneumonia
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 respiratory infections
MESH:D012640 fitness|virus fitness
MESH:D018352 CoV infection
rs1045642 Affx-204704025
A/G,T
ABCB1 5243 7:87509329 6
 32406606
Positive detection of SARS-CoV-2 combined HSV1 and HHV6B virus nucleic acid in tear and conjunctival secretions of a non-conjunctivitis COVID-19 patient with obstruction of common lacrimal duct.
Hu Y, et. al. (2020); Acta Ophthalmol; 2020 May 14 . doi:10.1111/aos.14456
MESH:C000657245 SARS-CoV-2 infection|Novel Coronavirus Pneumonia|2019-nCoV Infection|2019 novel coronavirus diseases|conjunctivitis COVID-19|Coronavirus Disease 2019|Covid-19|COVID-19|COVID
MESH:C565569 lifelong chronic infections
MESH:D000402 obstruction
MESH:D001102 virus disease|virus infection
MESH:D003231 conjunctivitis
MESH:D003371 cough
MESH:D003607 acute dacryocystitis
MESH:D003643 mortality
MESH:D005128 ocular diseases
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D006333 conjunctival congestion
MESH:D007153 immunodeficiency diseases
MESH:D007239 infections|infected|infection
MESH:D007244 infectious mononucleosis
MESH:D020031 Epstein-Barr virus infection
MESH:D051271 eye symptoms|Ocular symptoms
MESH:D060085 virus co-infection
 32864162
Pharmacogenomics of COVID-19 therapies.
Takahashi T, et. al. (2020); NPJ Genom Med; 2020 ; 5 35. doi:10.1038/s41525-020-00143-y
MESH:C000657245 SARS-CoV-2 pneumonia|coronavirus disease 2019|Coronavirus disease 2019|COVID-19-infected|Coronavirus Disease 2019|2019 coronavirus disease|Covid-19|COVID-19
MESH:D000080362 Stargardt disease|recessive Stargardt macular dystrophy
MESH:D000208 acute illness
MESH:D000275 depression
MESH:D000740 anemia
MESH:D000743 Hemolytic anemia|hemolytic anemia
MESH:D001102 virus infection
MESH:D001145 arrhythmias
MESH:D001172 rheumatoid arthritis|RA
MESH:D001327 autoimmune disease|autoimmune disorders
MESH:D003141 Infectious Diseases|Infectious Disease|infectious disease
MESH:D003643 mortality|Mortality|death
MESH:D003967 diarrhea
MESH:D004194 toxicities across multiple disease
MESH:D004342 allergy|hypersensitivity
MESH:D004670 California
MESH:D005076 rash
MESH:D005756 gastritis
MESH:D005955 G6PD deficiency|glucose-6-phosphate dehydrogenase (G6PD) deficient
MESH:D006086 graft-versus-host-disease
MESH:D006323 cardiac arrest
MESH:D006331 heart rhythm problems
MESH:D006333 heart failure
MESH:D006461 hemolysis|Hemolysis
MESH:D006526 HCV infection|HCV-infected|hepatitis C virus infection|HCV
MESH:D006932 hyperbilirubinemia
MESH:D006973 hypertension
MESH:D007153 G6PDH-deficient
MESH:D007239 Infection|infections|infection|infected
MESH:D007970 leukopenia
MESH:D008133 QT prolongation
MESH:D008180 systemic lupus erythematosus
MESH:D008268 maculopathy (toxic maculopathy)
MESH:D008288 malaria|malaria-infected
MESH:D009103 multiple sclerosis
MESH:D009196 myeloproliferative diseases
MESH:D009202 cardiomyopathy|myocardial injury
MESH:D009503 neutropenia
MESH:D009765 obesity
MESH:D010020 osteonecrosis
MESH:D011273 prolongation
MESH:D011605 psychosis
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012141 respiratory infections
MESH:D012164 Retinopathy|retinopathy|retinal diseases
MESH:D012598 sclerosis
MESH:D013921 Thrombocytopenia|thrombocytopenia
MESH:D013927 Thrombosis
MESH:D015658 HIV-infected|HIV|HIV-Infected|HIV human Immunodeficiency virus|HIV-1-infected
MESH:D016638 critically ill
MESH:D017093 liver injury|Liver injury
MESH:D018352 SARS-coronavirus infection
MESH:D018357 respiratory syncytial virus infection
MESH:D019698 chronic hepatitis C
MESH:D050171 dyslipidemia|Cytopenia, dyslipidemia
MESH:D056486 liver toxicity|liver damage
MESH:D064420 toxicity|Toxicity|toxicities
 32936528
Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19).
Zubiaur P, et. al. (2020); Clin Transl Sci; 2020 Sep 16 . doi:10.1111/cts.12866
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|2019-nCoV acute respiratory disease|novel coronavirus disease|CoV-2 Infection|Coronavirus Disease 2019|Covid-19|COVID-19|COVID
MESH:C536362 Castleman's disease
MESH:C537372 Multicentric Castleman's disease
MESH:C538614 renal-cell carcinomas
MESH:C562393 cutaneous melanoma
MESH:D000067390 cold
MESH:D000070603 osteonecrosis of the femoral head
MESH:D000163 AIDS
MESH:D000275 depression
MESH:D000740 malarial anaemia
MESH:D000743 hemolytic anemia|haemolytic anaemias
MESH:D001007 social anxiety disorder|anxiety disorders
MESH:D001102 virus infection|viral infections
MESH:D001172 rheumatoid arthritis
MESH:D001201 ascites
MESH:D001249 asthma
MESH:D001327 autoimmune diseases
MESH:D001523 aggression
MESH:D002318 cardiovascular diseases
MESH:D003141 infectious|fibrotic diseases
MESH:D003324 coronary artery disease
MESH:D003371 cough
MESH:D003643 deaths|died
MESH:D003920 diabetes
MESH:D003928 diabetic nephropathy
MESH:D004417 shortness of breath
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D005955 G6PD deficient|deficient glucose-6-phosphate dehydrogenase|G6PD deficiency|glucose-6-phosphate dehydrogenase deficiency
MESH:D006333 heart failure
MESH:D006391 hemangiomas
MESH:D006461 hemolysis|haemolysis crisis
MESH:D006509 hepatitis B
MESH:D006526 hepatitis C virus (HCV) infections
MESH:D006973 hypertension
MESH:D007153 deficiency can easily|deficiency|G6PDH-deficient
MESH:D007239 infection
MESH:D007249 inflammation
MESH:D007565 jaundice
MESH:D007674 proteinuric renal disease
MESH:D007943 hairy-cell leukemia
MESH:D008175 lung cancer
MESH:D008228 non-Hodgkin lymphoma
MESH:D008232 lymphoproliferative disorder
MESH:D008288 malaria|malaria infection|Malaria
MESH:D009101 myeloma|multiple myeloma
MESH:D009102 multi-organ failure
MESH:D009103 multiple sclerosis
MESH:D009203 myocardial infarcted
MESH:D009336 tumor necrosis
MESH:D009771 obsessive-compulsive disorder
MESH:D010146 pain
MESH:D010300 Bechet's disease
MESH:D010493 pericarditis
MESH:D010505 familial Mediterranean fever|Familial Mediterranean fever|FMF
MESH:D011014 pneumonia
MESH:D011087 myelofibrosis and polycythemia vera
MESH:D011565 psoriasis
MESH:D012128 acute respiratory distress syndrome
MESH:D012140 respiratory diseases
MESH:D012141 respiratory infection
MESH:D012514 Kaposi's sarcoma
MESH:D015047 zoonotic
MESH:D015179 colorectal cancer
MESH:D015464 chronic myelogenous leukemia
MESH:D015658 HIV infection|HIV-1 infection|HIV infections
MESH:D016584 panic disorder
MESH:D016779 cerebral malaria
MESH:D017577 hyperproliferative cutaneous disorders
MESH:D018352 MERS|Coronavirus disease|human coronavirus infections|MERS zoonotic|Middle East respiratory syndrome
MESH:D018512 parasitemia
MESH:D018754 ventricular dysfunction
MESH:D018805 sepsis
MESH:D029424 chronic obstructive pulmonary disease
MESH:D030361 papillomavirus infections
MESH:D034701 cutaneous diseases
MESH:D040921 traumatic stress disorder
MESH:D055370 lung injuries
MESH:D060085 secondary kidney diseases
MESH:D063806 myalgia
MESH:D064420 toxicity
 33205496
Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment.
Al-Eitan LN, et. al. (2020); Rev Med Virol; 2020 Nov 17 2194. doi:10.1002/rmv.2194
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|Coronavirus disease 2019|novel coronavirus pneumonia|SARS-CoV-2 infections|CoV-2 infection|coronavirus disease-2019|Covid-19|COVID-19|Covid 19 pneumonia
MESH:D000072658 NSTEMI
MESH:D000740 anemia|anaemia
MESH:D000743 Haemolytic anaemia|hemolytic anemia
MESH:D001102 viral diseases|viral infection
MESH:D001172 rheumatoid arthritis
MESH:D001327 autoimmune disease|autoimmune diseases
MESH:D001778 coagulopathy|coagulation
MESH:D002318 cardiovascular disease|cardiovascular diseases
MESH:D002544 ischemic stroke
MESH:D003371 coughing
MESH:D003643 mortality|deaths|mortalities|death
MESH:D003920 diabetes|diabetic
MESH:D003924 type-2 diabetes mellitus
MESH:D005334 fever
MESH:D006461 haemolysis
MESH:D006509 hepatitis B virus|hepatitis B HBeAg|hepatitis B|hepatitis B virus infection
MESH:D006526 thrombocytopenia in hepatitis C|HCV-infected|HCV
MESH:D006973 hypertension|hypertensive
MESH:D007153 immunodeficiency virus
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D008175 lung tumor
MESH:D008179 chronic discoid lupus erythematosus
MESH:D008180 systemic lupus erythematosus
MESH:D008288 malaria|malaria to autoimmunity
MESH:D009203 myocardial infarction
MESH:D009336 tumour necrosis
MESH:D010300 PD
MESH:D011014 pneumonia|lung inflammation
MESH:D012128 acute respiratory distress syndrome
MESH:D012131 lung failure
MESH:D012140 respiratory disease
MESH:D012141 lung infections|respiratory infections
MESH:D012216 rheumatic
MESH:D013921 thrombocytopenia
MESH:D015047 zoonotic
MESH:D015658 HIV-infected|HIV
MESH:D017093 decreased hepatic midazolam metabolism
MESH:D018352 coronavirus infection|Middle East Respiratory Syndrome|middle east respiratory syndrome|Middle East respiratory syndrome
MESH:D019698 chronic hepatitis C
MESH:D024821 metabolic syndrome
MESH:D052439 lipid toxicity
MESH:D054058 acute coronary syndrome|coronary syndrome
MESH:D055370 lung injury
MESH:D058186 acute renal failure
MESH:D063806 muscle pain
MESH:D064420 toxicity
 33542445
Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs.
Badary OA, et. al. (2021); Pharmacogenomics J; 2021 Feb 04 . doi:10.1038/s41397-021-00209-9
MESH:C000657245 covid-19|COVID-19 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|Coronavirus disease 2019|SARS-CoV-2 infections|CoV-2 infection|2019-nCoV infection|Covid-19|COVID-19
MESH:D000163 AIDS
MESH:D000275 depression
MESH:D000544 Alzheimer's diseases
MESH:D000740 anaemia|malarial anaemia
MESH:D000743 hemolytic anemia
MESH:D000799 angioedema
MESH:D001102 virus infection|immunodeficiency virus infection|viral infections
MESH:D001145 ventricular arrhythmias
MESH:D001172 rheumatoid arthritis|RA
MESH:D001201 ascites
MESH:D001284 atrophy
MESH:D001943 breast cancer
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003924 type 2 diabetes mellitus
MESH:D004342 hypersensitivity
MESH:D004827 epilepsy
MESH:D005076 rash|skin rash
MESH:D005955 Glucose-6-phosphate dehydrogenase (G6PD) deficiency
MESH:D006461 hemolysis|haemolysis
MESH:D006932 hyperbilirubinemia
MESH:D007239 malarial infection|falciparum Infection|infections|infected
MESH:D007249 inflammation
MESH:D007565 jaundice
MESH:D008060 lipodystrophy
MESH:D008133 QTc prolongation
MESH:D008171 pulmonary complications
MESH:D008180 systemic lupus erythematosus
MESH:D008268 maculopathy (toxic maculopathy)
MESH:D008288 malaria|malaria parasites
MESH:D009202 cardiomyopathy
MESH:D009369 cancers
MESH:D010009 SJS
MESH:D010300 Parkinson's
MESH:D012128 acute respiratory distress syndrome
MESH:D012141 respiratory tract infections
MESH:D012164 Retinopathy|retinopathy
MESH:D013262 Stevens-Johnson syndrome
MESH:D013927 thrombosis
MESH:D015228 hypertriglyceridemia and lipodystrophy
MESH:D015658 immunodeficiency virus (HIV)-infected|HIV-infected|hyperbilirubinemia in HIV-infected
MESH:D016638 critically ill
MESH:D016778 falciparum malaria
MESH:D016779 G6PD defciency on cerebral malaria
MESH:D018805 sepsis
MESH:D019142 Ebola virus disease
MESH:D020922 inflammation cross-talking
MESH:D039682 HIV-related lipodystrophy
MESH:D050171 dyslipidemia
MESH:D055370 lung injury
MESH:D056486 hepatotoxicity
MESH:D061325 lipodystrophic syndrome
MESH:D063806 myalgia
MESH:D064420 toxicity|drug toxicity
 33807592
Pharmacogenetics Approach for the Improvement of COVID-19 Treatment.
Fricke-Galindo I, et. al. (2021); Viruses; 2021 Mar 05 ; 13 (3) . doi:10.3390/v13030413
MESH:C000657245 covid-19|coronavirus disease 2019|Coronavirus disease 2019|CoV-2 infection|SARS-CoV-2 infected|2019 novel coronavirus-infected pneumonia|Covid-19|COVID-19
MESH:D000743 haemolytic anaemia|hemolytic anemia
MESH:D000860 hypoxia
MESH:D001102 virus disease|immunodeficiency virus-infected
MESH:D001249 asthma
MESH:D001943 breast cancer
MESH:D002908 chronic diseases
MESH:D003110 colon
MESH:D003141 infectious diseases
MESH:D003643 mortality|death
MESH:D003967 diarrhea
MESH:D004211 disseminated intravascular coagulation
MESH:D004827 epilepsy
MESH:D005221 fatigue
MESH:D005955 glucose-6 phosphate dehydrogenase deficiency|G6PD-deficient
MESH:D006402 blood leukocyte abnormalities
MESH:D006461 hemolysis
MESH:D006566 B infection
MESH:D007153 G6PDH-deficient
MESH:D007239 Infection|infected|infection
MESH:D007249 inflammation|Inflammation
MESH:D007566 Dubin-Johnson syndrome
MESH:D007938 Lymphoblastic Leukemia-Lymphoma
MESH:D008180 systemic lupus erythematosus
MESH:D008288 malaria
MESH:D009101 myeloma
MESH:D009202 myocardial injury
MESH:D009325 nausea
MESH:D009765 obesity
MESH:D010020 osteonecrosis
MESH:D012140 respiratory diseases
MESH:D012141 upper respiratory tract infection
MESH:D012164 retinopathy
MESH:D012640 seizure
MESH:D012772 septic shock
MESH:D012791 multisystem disorder
MESH:D012892 REM
MESH:D014839 vomiting
MESH:D015658 HIV infection|HIV-infected|saliva of HIV-infected|HIV-1-infected
MESH:D016638 critically ill
MESH:D017093 liver dysfunction
MESH:D018352 coronavirus diseases|CoV infection
MESH:D019636 neurodegenerative diseases
MESH:D020258 neurotoxicity
MESH:D030342 neuroinflammatory disorders
MESH:D051437 renal failure
MESH:D058186 acute kidney injury
MESH:D063806 myalgia
MESH:D064420 toxicity|Toxicity
rs1047286
G/A,C
C3 718 19:6713251 4
 32511494
Identification of Immune complement function as a determinant of adverse SARS-CoV-2 infection outcome.
Ramlall V, et. al. (2020); medRxiv; 2020 May 13 . doi:10.1101/2020.05.05.20092452
MESH:C000657245 adverse SARSCoV-2 infection|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-2 infections|covid|SARS-CoV-2 disease|CoV-2 infected|SARS-CoV-2 infected|CoV-2 infection|SARSCoV-2 infection|CoV-2 disease|COVID-19
MESH:D000782 aneuploidy
MESH:D001102 Viral infections
MESH:D001766 blindness
MESH:D001778 macular degeneration and coagulation disorders|coagulation disorder|disorders of coagulation|hyper-coagulative disorders|degeneration and coagulation disorders|coagulation disorders|blood coagulation|C19+ Coagulation
MESH:D002318 cardiovascular disease
MESH:D003324 coronary artery disease|Coronary Artery Disease
MESH:D003371 Cough|cough
MESH:D003643 mortality|Mortality|deaths|died|Death HR|death
MESH:D003920 diabetes
MESH:D003924 Type 2 Diabetes|type 2 diabetes
MESH:D003928 diabetic kidney disease
MESH:D005334 fever
MESH:D006009 AMD
MESH:D006470 bleeding|hemorrhage
MESH:D006973 Hypertension|hypertension
MESH:D007153 Complement deficiencies|C19+ Complement Def|complement deficiency disorders|complement deficiency disorder|complement disorders
MESH:D007239 infections|infection
MESH:D007249 inflammation
MESH:D008268 macular degeneration, complement deficiency disorders|macular degeneration or coagulatory dysfunctions
MESH:D009461 coagulatory dysfunction
MESH:D009765 C19+ Obesity|obesity
MESH:D012140 respiratory illness
MESH:D012162 degeneration
MESH:D013921 thrombocytopenia
MESH:D013927 thrombosis
MESH:D015047 Zoonotic infections
MESH:D016638 Critically
MESH:D018352 CoV infections
MESH:D034721 degeneration and the complement system
MESH:D056587 Complement Dysregulation and Disease
OMIM:217000 Complement Factor H (CFH) and Complement Component
OMIM:612348 complement activation disorders|hyper-active complement
 32747830
Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection.
Ramlall V, et. al. (2020); Nat. Med.; 2020 Aug 03 . doi:10.1038/s41591-020-1021-2
MESH:C000657245 CoV-2 infection|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-2-infected|Covid-19|COVID-19|COVID
MESH:D000782 aneuploidy
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001778 macular degeneration and coagulation disorders|coagulation disorder|dysregulated complement or coagulation systems impact disease|macular degeneration or coagulation disorders|coagulopathies|C19+ Coagulation|coagulation disorders|blood coagulation|CD disorders and disorders of coagulation|coagulation dysfunction
MESH:D002318 cardiovascular disease
MESH:D003324 coronary artery disease
MESH:D003371 Cough|cough|C19+ Cough
MESH:D003424 CD disorders
MESH:D003643 mortality|Mortality|deaths|died|Death HR|death
MESH:D003920 diabetes
MESH:D003924 Type 2 Diabetes
MESH:D003928 diabetic kidney disease
MESH:D006009 AMD
MESH:D006470 bleeding|hemorrhage
MESH:D006948 hyperactive complement
MESH:D006973 Hypertension|hypertension
MESH:D007153 complement deficiencies|complement deficiency disorders|complement deficiency disorder|complement disorders
MESH:D007239 infections|infection
MESH:D007249 inflammation
MESH:D008268 macular degeneration (macula), complement deficiency disorders|macular degeneration, coagulatory disorders
MESH:D009765 obesity|Obesity
MESH:D012131 respiratory failure
MESH:D012162 degeneration
MESH:D012640 fits|binomial fits
MESH:D013921 thrombocytopenia
MESH:D013927 thrombosis
MESH:D015658 human disease
MESH:D016638 Critically
MESH:D018352 CoV infections
MESH:D020246 venous thrombosis
MESH:D054556 venous thromboembolism
MESH:D056587 Complement dysregulation
MESH:D058745 error band
OMIM:612348 complement activation disorders
 33609539
A double edged-sword - The Complement System during SARS-CoV-2 infection.
Santiesteban-Lores LE, et. al. (2021); Life Sci; 2021 Feb 17 119245. doi:10.1016/j.lfs.2021.119245
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|SARS-CoV infection|Coronavirus disease 2019|SARS-CoV-2 infections|novel coronavirus pneumonia|novel coronavirus-infected pneumonia|SARS-CoV-2 infected|CoV-2 infection|2019-nCoV infection|COVID-19
MESH:C536439 endotheliitis
MESH:C537005 Complement C3 vs C5 inhibition|C5 Eculizumab
MESH:C565169 C3 deficient
MESH:D000783 vascular thrombi
MESH:D000799 Angioedema
MESH:D001102 viral infection|virus-infected|virus infection|virus infected|viral infections
MESH:D001778 coagulation and thrombolysis|coagulation disorders|dysfunctional coagulation|coagulation dysfunction|coagulopathy
MESH:D001791 platelet aggregation
MESH:D002318 cardiovascular diseases
MESH:D003643 deaths
MESH:D003920 diabetes
MESH:D004342 allergic
MESH:D004487 edema|endothelial injury (cell swelling
MESH:D004832 absence of GPI-linked Complement
MESH:D005334 fever
MESH:D005355 fibrosis
MESH:D006327 block excessive Complement
MESH:D006333 heart failure
MESH:D006402 hematologic disorders
MESH:D006457 Paroxysmal nocturnal haemoglobinuria|paroxysmal nocturnal hemoglobinuria|Paroxysmal Nocturnal Hemoglobinuria
MESH:D006463 Hemolytic Uremic Syndrome
MESH:D006470 hemorrhage
MESH:D007153 Complementing the inflammasome
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D007511 ischemia|ischemia and endotheliitis
MESH:D007674 renal injury
MESH:D007683 acute tubular necrosis
MESH:D008171 lung lesions|lung damage
MESH:D009102 multiple organ failure
MESH:D009157 myasthenia gravis
MESH:D009765 obesity
MESH:D009894 opportunistic infections
MESH:D011014 pneumonia
MESH:D011693 purpura|retiform purpura
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure|weight loss and less respiratory dysfunction
MESH:D013736 testis damage
MESH:D013921 thrombocytopenia
MESH:D013927 thrombus|thrombotic|thrombosis
MESH:D014947 endothelial injury
MESH:D015473 APL
MESH:D017093 liver cell necrosis
MESH:D017566 microvascular injury
MESH:D018352 coronavirus infections|MERS-CoV infection|coronavirus disease|respiratory syndrome coronavirus infection|coronavirus infection|CoV infection
MESH:D020246 deep vein thrombosis
MESH:D025861 Abnormal coagulation
MESH:D045169 severe acute respiratory syndrome
MESH:D054556 venous thromboembolism|Venous and arterial thromboembolic complications
MESH:D055370 lung injury|alveolar damage|lung injuries|pulmonary endothelial damage and dysfunction
MESH:D057049 thrombotic microangiopathy
MESH:D058186 acute kidney injury
MESH:D065766 Atypical hemolytic uremic syndrome
 33838929
SARS-CoV-2 associated Complement genetic variants possibly deregulate the activation of the Alternative pathway affecting the severity of infection.
Tsiftsoglou SA, et. al. (2021); Mol Immunol; 2021 Mar 26 . doi:10.1016/j.molimm.2021.03.021
MESH:C000657245 CoV-2 infection|SARS-CoV-2 infection|COVID-19|SARS-CoV-2 virus infection
MESH:C562924 DDD
MESH:C565169 complement C3 consumption|complement proteins C3|complement component C3|C3 SNPs|human complement component C3
MESH:D000079822 deposit disease
MESH:D001778 coagulation dysfunction
MESH:D005921 glomerulonephritis|glomerulonephritis type II
MESH:D006009 AMD
MESH:D006938 FH
MESH:D006948 hyperactive
MESH:D007239 infections|infection
MESH:D007249 inflammation|systemic inflammation
MESH:D007674 nephropathy|glomerular diseases
MESH:D009102 organ failure
MESH:D014657 vasculitis
MESH:D015432 MPGN II
MESH:D017093 liver injury
MESH:D056647 systemic vasculitis
MESH:D058186 Acute kidney injury
rs1048803
G/T
NRP1 8829 10:33180283 1
 33532777
Effect of mutations in the SARS-CoV-2 spike protein on protein stability, cleavage, and cell-cell fusion function.
Barrett CT, et. al. (2021); bioRxiv; 2021 Jan 25 . doi:10.1101/2021.01.24.428007
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2 infected|CoV-2 infection|SARS-CoV-2-infected|coronavirus disease of 2019|SARS-CoV-2 fitness|COVID-19|hepatitis virus CoV S
MESH:D001102 viral infection
MESH:D003110 colon carcinoma LoVo|colon carcinoma
MESH:D003141 infectious diseases
MESH:D003643 death
MESH:D007239 Infection|infections|infection|infected
MESH:D007898 black arrows
MESH:D008175 Lung Cancer
MESH:D009102 multiple organ failure
MESH:D009369 cancer
MESH:D011014 Pneumonia|pneumonia
MESH:D012128 acute respiratory distress syndrome
MESH:D013927 thrombosis
MESH:D015047 zoonotic|Zoonotic Bat Coronavirus Infection
MESH:D018352 Coronavirus Tropism|respiratory syndrome coronavirus infection|Middle East respiratory syndrome coronavirus infection|respiratory syndrome coronavirus entry|coronavirus tropism
MESH:D018455 pCAGGS-S
MESH:D045464 Hendra Virus F
rs104886029
G/A
KRAS 3845 12:25227348 1
 26878082
An Overview of Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy.
Pillaiyar T, et. al. (2016); J. Med. Chem.; 2016 07 28; 59(14) 6595-628. doi:10.1021/acs.jmedchem.5b01461
- glycemia|SI
MESH:C000657245 mock-infected and SARS-CoV infected Vero|CoV|SARS-CoV infected Vero|SARS-CoV 3CL|Miscellaneous SAR-CoV|Miscellaneous SARS-CoV|SARS-CoV
MESH:C536029 UCH-L1
MESH:C537160 HTS
MESH:C537985 PDB ID|PDB ID 1P9U
MESH:C565529 peptidic SARS-CoV
MESH:D000544 Alzheimer's disease
MESH:D000789 unstable angina
MESH:D001102 viral infection|viral infections
MESH:D001168 inflammatory arthritis
MESH:D001528 Behcet's disease
MESH:D001991 infectious bronchitis virus|infectious bronchitis
MESH:D002357 articular cartilage
MESH:D002493 central nervous system diseases
MESH:D003072 cognitive decline
MESH:D003643 deaths CFRb|deaths|death
MESH:D003773 SARS-CoV plaque reduction
MESH:D003920 diabetes|diabetic
MESH:D003967 diarrhea
MESH:D004417 dyspnea
MESH:D004679 encephalomyelitis
MESH:D005759 gastroenteritis
MESH:D006261 headache
MESH:D006526 hepatitis C|hepatitis C virus NS3
MESH:D006527 Wilson's disease
MESH:D007153 immunodeficiency
MESH:D007239 infection
MESH:D008231 lymphopenia
MESH:D009800 low toxicity
MESH:D011014 pneumonia
MESH:D012131 respiratory illness|respiratory syndrome
MESH:D012141 respiratory tract infections
MESH:D012817 gastrointestinal symptoms
MESH:D014355 Chagas' disease
MESH:D014923 Leu-NHCH-(CH2CH2CON(CH3)2)-CHO
MESH:D015217 heterocyclic ester
MESH:D015431 weight loss
MESH:D015658 immunodeficiency virus (HIV)-luc
MESH:D018352 coronavirus infections|Coronavirus|SARS coronavirus infection|coronavirus mouse hepatitis virus|SARS coronavirus catalyzes|Middle East respiratory syndrome|respiratory syndrome coronavirus|coronavirus|respiratory syndrome coronavirus papain|coronavirus infection|MERS|Middle East respiratory syndrome coronavirus infection Middle East respiratory syndrome coronavirus
MESH:D018805 sepsis
MESH:D045169 SARS|acute respiratory syndrome|SARS-3CL|SARS SARS-CoV|SARS infection
MESH:D056486 hepatitis
MESH:D064420 toxicity
OMIM:612348 Active Heterocyclic
rs104893790
G/A
RHO 6010 3:129529002 1
 28882889
The Rho ADP-ribosylating C3 exoenzyme binds cells via an Arg-Gly-Asp motif.
Rohrbeck A, et. al. (2017); J. Biol. Chem.; 2017 10 27; 292(43) 17668-17680. doi:10.1074/jbc.M117.798231
MESH:C000657245 SARS-CoV
MESH:C554498 AIDS Kaposi sarcoma
MESH:C565169 TAT-C3|C3 or C3-RGD|C3-RGD|enzyme-deficient C3-E174Q
MESH:D001424 bacterial infections
MESH:D004660 encephalitis
MESH:D006566 herpesvirus infection
MESH:D007239 infection
MESH:D009369 cancer
MESH:D009373 embryonic
MESH:D010051 hamster ovary CHO
MESH:D012131 respiratory syndrome
MESH:D012514 Kaposi's sarcoma
MESH:D014376 tuberculosis-infected
MESH:D015658 virus infection
MESH:D018352 SARS coronavirus|SARS-coronavirus spike
MESH:D020521 strokes
rs104893875
C/T
SNCA 6622 4:89828170 1
 33803185
The Nigral Coup in Parkinson's Disease by alpha-Synuclein and Its Associated Rebels.
Sian-Hulsmann J, et. al. (2021); Cells; 2021 Mar 09 ; 10 (3) . doi:10.3390/cells10030598
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2 infected|CoV-2 infected|SARS-CoV-2-infected|COVID 19|Covid-19|COVID-19|COVID
MESH:C535733 der Substantia nigra pars compacta beim idiopathischen Parkinson-Syndrom.Structure
MESH:C537475 Mitochondrial complex I deficiency
MESH:C562385 iron dyshomeostasis
MESH:C566823 autosomal-dominant parkinsonism
MESH:D000068079 motor dysfunction|motor abnormalities
MESH:D000079225 Stress
MESH:D000080874 alpha-synucleinopathy|neurodegenerative synucleinopathies
MESH:D000370 hypogeusia
MESH:D000544 Alzheimer's disease|Alzheimer's disease brains
MESH:D000857 Hyposmia|hyposmia
MESH:D000860 hypoxia
MESH:D001102 viral infection|immunodeficiency virus-infected|immunodeficiency virus infection|viral infections
MESH:D001284 atrophy
MESH:D001480 extrapyramidal movement disorders
MESH:D001927 encephalopathy|Encephalopathy
MESH:D002534 hypoxic brain injury
MESH:D003141 LB disease
MESH:D003643 Death|neurodegenerative cell death
MESH:D003693 delirium
MESH:D003704 dementia
MESH:D003711 demyelinating disease
MESH:D003920 diabetes
MESH:D004409 akinesia
MESH:D004660 encephalitis
MESH:D004672 encephalitis B
MESH:D005911 gliosis
MESH:D006333 autonomic failure
MESH:D006432 iron storage disease
MESH:D006623 Verteilung von Noradrenalin
MESH:D007153 deficiency|immunodeficiency virus/HIV
MESH:D007239 Infections|Infection|infected|infection
MESH:D007249 inflammation|acute inflammation
MESH:D008569 memory T
MESH:D008659 metabolic diseases
MESH:D009069 Movement disorders
MESH:D009127 Hypokinetic-rigid movement disorders
MESH:D009336 Tumor necrosis
MESH:D009410 neuronal loss|SN neuronal loss|neuronal dysfunction|neuronal necrosis|neuronal cell death|SN neuronal degeneration|neuronal damage
MESH:D009421 neurological defects
MESH:D009422 neurological symptoms
MESH:D009443 Lewy neuritis
MESH:D009461 motor deficits|dysfunctional
MESH:D010300 Parkinson's Disease|idiopathic Parkinson's disease|PD brains|Parkinson's|PD|parkinsonsim and Parkinson's disease|Parkinson's disease|familial Parkinson's disease|Parkinson disease|PD-like injury|Lewy bodies of Parkinson disease|Parkinson Disease|neurodegenerative disorder Parkinson's disease|Idiopathic Parkinson's disease|Parkinson's disease-a multifactorial neurodegenerative disorder|autosomal dominant PD
MESH:D010301 encephalitis lethargica|encephalitic parkinsonism|postencephalitic parkinsonism|Encephalitis lethargica
MESH:D010302 Parkinson|parkinsonism
MESH:D010859 pigmentation
MESH:D012120 respiratory syndrome
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012162 degeneration via microgliosis
MESH:D012791 systems atrophies|degeneration in multiple systems atrophy
MESH:D013167 Spondyloarthritis
MESH:D013226 status epilepticus
MESH:D013651 mitochondriopathy, dysfunction of metal homeostasis
MESH:D014202 tremor
MESH:D015526 HIV dementia|Parkinsonism in HIV dementia|AIDS Dementia Complex
MESH:D015658 HIV-infected|HIV infection
MESH:D016464 lysosomal disorders
MESH:D018352 coronavirus disease
MESH:D018476 bradykinesia
MESH:D019636 neurodegenerative disorders|neurodegenerative maladies|Neurodegeneration|neurodegenerative diseases|neurodegeneration|SN neurodegeneration|neurodegenerative disorder
MESH:D020031 Epstein-Barr
MESH:D020258 neurotoxic|neurotoxicity
MESH:D020271 Neurological Diseases
MESH:D020521 strokes
MESH:D020734 parkinsonian deficits|autosomal recessive parkinsonism|parkinsonian brains|Parkinson-like syndrome|parkinsonian|parkinsonian brain
MESH:D020961 Lewy body disease|Lewy body diseases
MESH:D028361 mitochondrial deficits|mitochondrial dysfunction|Mitochondrial dysfunction
MESH:D030342 genetic defect|genetic abnormality|neuropathogenesis of the disorder
MESH:D034721 system dysfunction
MESH:D057165 proteostasis
MESH:D064420 cytotoxicity|toxicity
MESH:D065703 Neuronal Apoptosis
OMIM:256040 proteasomal dysfunction
rs104893877
C/T
SNCA 6622 4:89828149 7
 24752582
27th International Mammalian Genome Conference meeting report.
Gamache B, et. al. (2014); Mamm. Genome; 2014 Jun; 25(5-6) 195-201. doi:10.1007/s00335-014-9513-3
- Laia Capilla|SINEUPs|PWD|inaugural Lorraine Flaherty Awards
MESH:C000657245 SARS-CoV-induced vascular cuffing|SARS-CoV-induced vascular
MESH:C536767 Cristina Vicente Garcia
MESH:C563985 melanoma candidate cancer
MESH:D000080874 synucleinopathies
MESH:D000219 genesis Elizabeth Adams
MESH:D000275 depressive disorder
MESH:D000544 Alzheimer's disease
MESH:D001008 anxiety
MESH:D001102 viral infection
MESH:D001943 breast cancer
MESH:D002658 neurodevelopmental disorders
MESH:D003047 valley fever
MESH:D003638 deafness
MESH:D003920 diabetes
MESH:D005124 morphological abnormalities in the eye
MESH:D005148 facial defects
MESH:D005862 Autonoma de Barcelona
MESH:D005910 glioma
MESH:D006313 sensorineural
MESH:D006323 mitotic arrest
MESH:D006331 cardiac disease
MESH:D006528 hepatocellular carcinoma
MESH:D007153 Nek8-deficient
MESH:D007239 A infection|infections
MESH:D007251 influenza A virus infection
MESH:D007674 kidney disease
MESH:D007690 polycystic kidney disease
MESH:D008223 lymphoma
MESH:D008288 malaria
MESH:D008545 melanoma|melanomas
MESH:D009362 metastases
MESH:D009369 cancer|Science Okumura Kazuhiro Chiba Cancer|del Cancer|tumour
MESH:D010300 Parkinson's disease
MESH:D012162 retinal degeneration
MESH:D012295 rift valley fever
MESH:D012640 fitness Verne Chapman Award Lisa Gralinski
MESH:D012878 skin tumour
MESH:D013927 thrombosis
MESH:D015518 Rett Syndrome disease
MESH:D018798 dietary deficiency
MESH:D019636 neurodegeneration'
MESH:D030342 inherited polyposis
MESH:D034381 hearing loss
MESH:D054331 choice Sonia Castillo-Lluva Instituto de Biologia Molecular y Celular del Cancer
OMIM:614962 diabetic leptin
 28516028
Digested disorder: Quarterly intrinsic disorder digest (April-May-June, 2013).
DeForte S, et. al. (2013); Intrinsically Disord Proteins; 2013 Jan-Dec; 1(1) 27454. doi:10.4161/idp.27454
MESH:C000657245 SARS-CoV N
MESH:C535838 pancreatic islet amyloid
MESH:C536108 disordered N-terminus
MESH:C536599 disordered protein Tau
MESH:C562903 disordered tails
MESH:C563168 Ewing's sarcoma
MESH:D000544 Alzheimer|Alzheimer disease
MESH:D001796 Protein disorder|protein disorder|disordered proteins|disordered protein
MESH:D002318 cardiovascular disease
MESH:D003920 Diabetes
MESH:D003924 type 2 diabetes|Type 2 diabetes
MESH:D008133 long disordered
MESH:D009103 ESI-MS
MESH:D009369 cancer|tumor
MESH:D009436 NTD
MESH:D010300 Parkinson disease
MESH:D014123 Toxoplasma gondii
MESH:D014693 fibrillation
MESH:D019636 neurological diseases|neurodegenerative diseases
MESH:D020919 intrinsic disorder|intrinsic protein disorder|ubiquity of intrinsic disorder|protein intrinsic disorder|Intrinsic disorder|Protein intrinsic disorder|Intrinsic structural disorder
MESH:D028361 structural disorder|Structural disorder
MESH:D030342 disordered hub|disordered immunodominant epitope|disordered|Disordered|gallery of disorder
MESH:D064420 cytotoxicity
OMIM:300855 disordered N-terminal
 33039660
Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases.
Li L, et. al. (2020); Brain Behav Immun; 2020 Oct 08 . doi:10.1016/j.bbi.2020.10.007
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2-infected|coronavirus disease-2019|COVID-19|COVID19 Infect
MESH:C535882 Johnson
MESH:C536050 OGD
MESH:C536395 HSV encephalitis|HSV-1 infection|HSV-2 infection
MESH:C538265 IC Attenuates Reactive Astrogliosis
MESH:C566985 brain atrophy
MESH:D000067390 Cold
MESH:D000070642 Traumatic Brain Injury|traumatic brain Injury|traumatic brain injury
MESH:D000080874 synucleinopathies|synucleinopathy
MESH:D000163 AIDS brains|acquired immunodeficiency syndrome|AIDS
MESH:D000370 hypogeusia/hyposmia|ageusia
MESH:D000544 Alzheimer|Alzheimer's disease|Alzheimer disease brains|Alzheimer's Disease|AD|Alzheimer disease
MESH:D000690 amyotrophic lateral sclerosis|Amyotrophic lateral sclerosis
MESH:D000783 spinal cord ischemia
MESH:D000857 anosmia
MESH:D001102 Neurotropic virus infections|Virus Infections|virus-infected|Viral diseases|viral infections|Infectious Diseases Viral infection|Viral infections|Virus Infection|virus infection|viral infection
MESH:D001327 autoimmunity
MESH:D001424 bacterial infections|astroglial TLRs in bacterial infections|bacterial infection
MESH:D001480 axonal damage
MESH:D001523 behavioral deficits|neuro-psychiatric disorders
MESH:D001925 brain damage|Brain Damage
MESH:D001927 encephalopathy
MESH:D001930 ischemic brain injury
MESH:D002006 Brucella infections|Brucella abortus infection|Brucella infection|brucellosis increases
MESH:D002493 astroglial TLRs in CNS disease|CNS dysfunction|CNS injury and disease|Traumatic CNS injury|CNS injury|CNS disorders|traumatic CNS injuries|astroglial TLRs to CNS injuries|CNS disease and injury
MESH:D002494 central nervous system infection|astroglial TLRs in CNS infections|CNS infections|CNS infections via involvement of TLRs|Infections of the Central Nervous System|CNS infection|central nervous system infections
MESH:D002534 hypoxic injury|hypoxic damage
MESH:D002544 ischemic focal stroke|artery ischaemic stroke
MESH:D002545 Cerebral Ischemia|cerebral ischemia|brain ischemia
MESH:D002561 cerebrovascular disease
MESH:D003072 memory loss and cognitive deficits|cognitive impairment|Cognitive impairment|HIV infection of the brain impairs cognitive
MESH:D003141 cardiorespiratory disease|infectious diseases
MESH:D003643 mortality|Death|death|Mortality and Disease
MESH:D003711 demyelination|chronic demyelinating disease
MESH:D004194 Damage and Lethal Disease|injuries and diseases
MESH:D004487 swelling|ischemia Astrocyte swelling/edema|edema
MESH:D004660 meningitis/encephalitis|Encephalitis|encephalitis
MESH:D004673 acute disseminated encephalomyelitis
MESH:D004679 encephalomyelitis
MESH:D005911 white matter gliosis|gliosis
MESH:D005935 Tumor Necrosis Factor-alpha
MESH:D006313 Neurosensory dysfunction
MESH:D006333 heart failure
MESH:D006816 HD|Huntington's disease|Huntington disease
MESH:D006984 hypertrophy
MESH:D007027 hypothalamic
MESH:D007153 immunodeficiency virus|TLR4 deficiency|TLR3 Deficiency|TLR deficiency|TLR3 deficiency
MESH:D007154 immune system failure
MESH:D007239 Infections|infection|Infection|Infected|life-long infection|infections|infected|neuronal infection
MESH:D007249 inflammation|RAGE-TLR Crosstalk Sustains Chronic Inflammation|inflammatory disease|Inflammation
MESH:D007511 ischemic
MESH:D008107 ALS-like disease
MESH:D008113 familial ALS
MESH:D008581 meningitis
MESH:D008831 microcephaly and congenital brain anomalies
MESH:D009103 multiple sclerosis|multiple sclerosis brain
MESH:D009336 necrotic
MESH:D009369 cancer|Tumor
MESH:D009410 neuronal death|neuronal degeneration|neuronal loss|neuronal injury|neuronal damage|neuronal toxicity|axonal degeneration
MESH:D009422 neurological symptoms|nervous system injury and disease|neurological dysfunction|neurological disorders|Non-Cell-Autonomous Neurodegeneration|Neurological Disorders
MESH:D009437 neuropathic pain
MESH:D009461 degeneration and dysfunction|neurological deficits
MESH:D010146 pain
MESH:D010243 paralysis
MESH:D010300 Parkinson's Disease|Neuropathology of Parkinson disease|PD|Abeta Neuronal death Parkinson's Disease|Parkinson's disease|Parkinson's disease brain|Parkinson's disease brains
MESH:D010301 encephalitic
MESH:D011273 prolongs neuroinflammation
MESH:D011537 itch
MESH:D012131 respiratory failure
MESH:D012598 sclerosis|Sclerosis
MESH:D012640 seizures
MESH:D012769 heat shock proteins
MESH:D012892 glucose deprivation
MESH:D013118 spinal cord astrocytic swelling
MESH:D013119 spinal cord injuries|spinal cord injury
MESH:D013120 glia of ALS spinal cord
MESH:D014901 WNV infections
MESH:D014947 injuries
MESH:D015047 zoonotic
MESH:D015427 spinal cord ischemia-reperfusion injury
MESH:D015526 AIDS dementia
MESH:D015658 HIV-infected|HIV infection|HIV-1 infection|immunodeficiency virus type 1 infection
MESH:D016263 HIV-1-associated neuropathology
MESH:D016920 bacterial meningitis
MESH:D017827 Joseph
MESH:D018177 flavivirus infections|flavivirus infection
MESH:D018352 coronavirus infections|MERS|coronavirus infection|Middle East Respiratory Syndrome|Middle East respiratory syndrome coronavirus infection
MESH:D018980 Williams
MESH:D019636 Neurodegeneration|injury and neurodegenerative diseases|neurodegenerative diseases|neurodegeneration|Neurodegenerative diseases|neurodegenerative disorders|astroglial TLRs to neurodegenerative diseases|neurodegenerative disorder|neurodegenerative disease
MESH:D019965 neurocognitive impairment
MESH:D020258 astrocyte neurotoxicity|Neurotoxic|neurotoxic
MESH:D020271 neurological disease
MESH:D020295 degeneration of ventral midbrain
MESH:D020521 stroke|Stroke
MESH:D045169 Severe Acute Respiratory Syndrome Coronavirus Infection
MESH:D056486 hepatitis coronavirus
MESH:D056784 white matter lesions
MESH:D064420 toxicity
 33504982
Diversity and versatility of p38 kinase signalling in health and disease.
Canovas B, et. al. (2021); Nat Rev Mol Cell Biol; 2021 Jan 27 . doi:10.1038/s41580-020-00322-w
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2-infected|Novel Coronavirus Disease|COVID-19|COVID
MESH:C536030 muscle mass loss
MESH:C536594 bone loss Alzheimer disease
MESH:C536599 Tau hyperphosphorylation in Alzheimers disease|hyperphosphorylated Tau proteins
MESH:C537492 AOM
MESH:C566351 various disease
MESH:C567275 tumours CDD
MESH:C580065 episodic memory
MESH:D000067877 autism spectrum disorder
MESH:D000079225 stress|Osmotic stress|genotoxic stress|Stress
MESH:D000080902 nerve injury
MESH:D000230 pancreatic adenocarcinoma
MESH:D000275 depression
MESH:D000544 episodic memory NCT03402659 Alzheimer disease|hallmark of Alzheimer disease|Alzheimer|Alzheimer's disease|Alzheimer disease-linked|Alzheimer's Disease|Alzheimer disease
MESH:D000690 amyotrophic lateral sclerosis
MESH:D000782 aneuploidy|aneuploid
MESH:D000860 hypoxia
MESH:D001102 viral infection|viral infections
MESH:D001168 autoimmune arthritis|aheumatoid arthritis|arthritis
MESH:D001172 RA Streptococcus aureus|Rheumatoid arthritis|rheumatoid arthritis|RA
MESH:D001249 asthma
MESH:D001327 autoimmune disorders
MESH:D001847 bone remodelling
MESH:D001859 bone loss
MESH:D001943 breast cancer metastases|breast and lung cancer|breast cancer|metastasis of breast cancer|breast cancer metastasis
MESH:D001991 bronchitis
MESH:D002100 cachexia|cancer cachexia
MESH:D002311 Dilated Cardiomyopathye
MESH:D002318 ischaemic cardiovascular events|cardiovascular diseases
MESH:D002908 chronic diseases
MESH:D003072 cognitive impairment|cognitive dysfunction|cognitive impairments
MESH:D003092 colitis-associated tumor initiation
MESH:D003110 colon tumour|colon tumours|colon adenocarcinoma
MESH:D003324 myocardial ischaemia|myocardial ischemia
MESH:D003586 cytomegalovirus infection
MESH:D003643 cardiomyocyte death
MESH:D003704 dementia
MESH:D003807 platinum-sensitive ovarian cancer
MESH:D004194 multifactorial disease
MESH:D004342 pain hypersensitivity
MESH:D004417 dyspnoea
MESH:D004487 swelling
MESH:D004646 emphysema
MESH:D005234 liver steatosis|steatosis|steatohepatitis|fatty liver disease|alcoholic fatty liver disease
MESH:D005355 fibrosis|cardiac fibrosis
MESH:D005909 glioblastoma
MESH:D006130 tumour growth
MESH:D006323 arrest
MESH:D006331 heart ischaemia
MESH:D006333 heart failure
MESH:D006528 liver cancer
MESH:D006816 Huntington|Huntington disease
MESH:D006948 hyperactivity
MESH:D006965 hyperplasia
MESH:D006984 hypertrophy|hypertrophy of cardiomyocytes
MESH:D007027 hypothalamic
MESH:D007154 immune disorders|immune diseases
MESH:D007239 Infection|tuberculosis infection|infection
MESH:D007249 inflammatory diseases|inflammation|skin inflammation|Inflammation|colon inflammation
MESH:D007414 intestinal carcinomas
MESH:D007938 MLL-AF9 leukaemias|leukaemia
MESH:D008107 liver diseases
MESH:D008113 ALS|liver tumours
MESH:D008175 KRAS-addicted lung cancer|lung tumor|lung tumours
MESH:D008545 melanoma
MESH:D008569 spatial memory deficit Autism|impaired spatial learning memory and degenerating neurons Alzheimer disease
MESH:D008659 metabolic diseases|metabolic disease
MESH:D009101 multiple myeloma
MESH:D009133 muscle-wasting syndrome|muscle atrophy|skeletal muscle wasting
MESH:D009135 muscle loss
MESH:D009136 muscular dystrophy
MESH:D009202 cardiomyopathy|myocardial injury|Cardiomyopathy
MESH:D009203 myocardial infarction
MESH:D009362 visceral metastases|metastases
MESH:D009369 tumour niche|Cancer|tumoural myeloid|tumor|Non-cancer|graft failure Cancer|tumour types Cancer Acute myeloid leukaemia|carcinoma|tumour stroma|hyaluronan cancer|tumour initiation|malignancies|tumors|tumours|Tumour stroma|aneuploid cancer|cancer|impairs tumour progression Cancer|tumour
MESH:D009410 hypothalamic neuronal|neuronal death|mitochondrial abnormalities and neuronal degeneration|decreased loss of dopaminergic neurons
MESH:D009437 neuropathic pain
MESH:D009765 obesity
MESH:D010051 ovarian cancer
MESH:D010146 pain
MESH:D010190 pancreatic cancer
MESH:D010300 Parkinson disease|Parkinson's disease
MESH:D010930 Yersinia pestis YopJ
MESH:D011129 retards peripheral myelination
MESH:D011649 pulmonary alveolar regeneration
MESH:D011681 asynchronous oscillations
MESH:D012175 Retinoblastoma|retinoblastoma
MESH:D012509 sarcomas
MESH:D012640 fitness|competitive fitness
MESH:D012769 hyperosmotic shock|shock|shock proteins
MESH:D012878 skin cancer
MESH:D015009 Yersinia enterocolitica infection
MESH:D015179 colorectal cancer|Colon cancer|colon cancer|colorectal adenocarcinoma|colorectal tumours
MESH:D015427 reperfusion injury|ischaemia-reperfusion
MESH:D015470 acute myeloid leukemia
MESH:D017093 liver fibrogenesis|liver injury
MESH:D019636 neurodegenerative diseases|neurodegeneration
MESH:D020279 myelination or neuroinflammation
MESH:D020295 Stemness
MESH:D020961 Lewy body dementia
MESH:D021441 pancreatic ductal carcinoma
MESH:D027601 polyomavirus middleT
MESH:D028361 mitochondrial dysfunction
MESH:D029424 Chronic obstructive pulmonary disease|chronic obstructive pulmonary disease|COPD NCT00559910 Autoinflammatory disease|COPD
MESH:D050197 atherosclerosis
MESH:D054198 acute lymphoblastic leukaemia
MESH:D063806 muscle catabolism
MESH:D064420 cytotoxicity|toxicity|cytotoxicity Cancer
 33530458
Human iPSC-Based Modeling of Central Nerve System Disorders for Drug Discovery.
Qian L, et. al. (2021); Int J Mol Sci; 2021 Jan 26 ; 22 (3) . doi:10.3390/ijms22031203
MESH:C000657245 Coronavirus Disease 2019|coronavirus disease 2019|SARS-CoV-2 infection|Coronavirus disease 2019|iPSC-NPCs, iPSC-astrocytes and glioblastoma SNB-19|COVID-19
MESH:C536954 telencephalic
MESH:C537254 acute hemorrhagic necrotizing encephalopathy
MESH:C562760 stroma capillaries
MESH:C563003 FTD|FTD-ALS
MESH:D000014 functional defect|birth defects|neurogenic defects
MESH:D000067562 late-onset disease
MESH:D000067877 autism spectrum disorders
MESH:D000080874 synucleinopathies
MESH:D000275 depression
MESH:D000544 Alzheimer's Disease|AD hallmarks|Familial AD|familial AD brain|Alzheimer's disease pathology|Alzheimer|wholesome abnormalities of the AD brain|Alzheimer's disease|AD cytopathies|AD dementia|Alzheimer's dementia|familial AD organoids|AD|Alzheimer disease|Alzheimer's disease-like cytopathy
MESH:D000690 Amyotrophic Lateral Sclerosis|sporadic amyotrophic lateral sclerosis|amyotrophic lateral sclerosis
MESH:D000860 hypoxia
MESH:D001102 virus disease|Virus Disease|viral diseases|viral infection|virus infection
MESH:D001254 astrocytic dysfunction
MESH:D001284 atrophy
MESH:D001523 behavioral deficits|psychiatric disorders|neuropsychiatric disease|apathy-associated neuropsychiatric alterations|neuropsychiatric disorders
MESH:D001927 frontal lobe dysfunctions
MESH:D001943 breast cancer
MESH:D002303 neuronal SBFs falls
MESH:D002318 cardiovascular disease
MESH:D002493 CNS diseases|CNS disease|Modeling central nervous system diseases
MESH:D002658 developmental delays
MESH:D002869 chromosomal abnormalities
MESH:D003072 cognitive declines|cognitive impairment
MESH:D003141 infectious diseases|iPSC disease
MESH:D003643 increase cell deaths|deaths|mortalities|death
MESH:D003704 dementia
MESH:D004402 Modelling familial dysautonomia|Familial dysautonomia|FD lymphoblasts|Familial Dysautonomia|FD|familial dysautonomia|FD rNCs|FD-iPSC
MESH:D004660 meningitis/encephalitis
MESH:D004827 epilepsy
MESH:D005909 glioblastoma
MESH:D006323 proliferation arrest
MESH:D006331 cardiac glycosides
MESH:D006816 HD iPSCs|iPSCs Huntington's disease|HD|HD mHTT aggregation|Huntington's Disease|HD iPSC-neurons|Huntington's disease
MESH:D006948 hyperactivity
MESH:D006973 hypertensive vomiting attacks
MESH:D007022 pluripotent stem cell blood-brain
MESH:D007027 hypothalamic organoids
MESH:D007029 Hypothalamus
MESH:D007153 deficiency|immunodeficient
MESH:D007239 ZIKV-infected|infection immune diseases|infected|infection
MESH:D007249 inflammation|neuro-inflammation
MESH:D007319 initiation
MESH:D007635 dendritic deterioration
MESH:D008569 memory deficits|memory loss
MESH:D008607 flame retardants
MESH:D008659 metabolic dysfunction|metabolic disorders
MESH:D008831 microcephaly
MESH:D009127 rigidity
MESH:D009133 muscle wasting
MESH:D009336 necrosis
MESH:D009358 congenital defects like microcephaly
MESH:D009369 cancer
MESH:D009410 neuronal degeneration|neuronal death|vmDAns neuron degeneration|neuronal loss|neuron loss|axonal degeneration
MESH:D009422 neurological symptoms|neurological disorders|neuropathologies
MESH:D009443 soma and neuritis|neuritis
MESH:D009461 MN dysfunction
MESH:D010300 Parkinson's Disease|PD iPSC-vmDAns|PD iPSC-astrocytes|PD|Parkinson's disease|PD astrocyte dysfunction
MESH:D010302 parkinson
MESH:D011371 Hutchinson-Gilford progeria syndrome
MESH:D011595 fluidic agitation
MESH:D011605 psychosis, meningitis
MESH:D012120 respiratory syndromes
MESH:D012140 respiratory disease
MESH:D012141 loss of upper
MESH:D012162 vmDAn degeneration|degeneration of vmDAns
MESH:D012192 leukaemia retrovirus|leukemia retrovirus
MESH:D012640 convulsive|convulsion|Convulsion|seizures|convulsions
MESH:D014202 tremor
MESH:D014277 epileptiform
MESH:D014766 viremia and fetal brain abnormalities
MESH:D014832 disturbance/seizurogenic
MESH:D015518 Rett syndrome
MESH:D016135 Spina bifida
MESH:D016171 TDP-43M337V iPSC-MNs
MESH:D016657 cerebral amyloid angiopathy
MESH:D018302 neuroepithelial rosettes
MESH:D018319 neurogenic deficiency
MESH:D018476 bradykinesia
MESH:D018980 Williams
MESH:D019217 NPCs attrition
MESH:D019636 neurodegenerative disorders|neurodegenerative diseases|neurodegeneration|neurodegenerative disease|excitotoxicity in neurodegenerative disorders|autosomal dominant neurodegenerative disease
MESH:D020258 vhCOs recapitulates neurotoxicity|neurotoxic|neurotoxicity
MESH:D020271 neurological diseases|congenital neurodegenerative disease
MESH:D020288 iPSC-Choroid plexus
MESH:D020295 loss of ventral midbrain
MESH:D020721 iPSC Disease Modeling
MESH:D020886 proprioceptive sensory loss
MESH:D020961 Lewy body dementia
MESH:D030342 genetic diseases
MESH:D051271 Non-cognitive symptoms
MESH:D054081 impairment and cell migration defects
MESH:D057174 FTLD
MESH:D057177 TDP-43 proteinopathy
MESH:D058225 Alzheimer-type amyloid deposits
MESH:D060825 NCC impairment
MESH:D062787 overdose
MESH:D063646 carcinogenesis
MESH:D064420 cytotoxicity|toxicity|Drug Toxicity|Toxicity|Drug toxicity|Cytotoxicity|drug toxicity
MESH:D066126 cardiotoxicity
 33803185
The Nigral Coup in Parkinson's Disease by alpha-Synuclein and Its Associated Rebels.
Sian-Hulsmann J, et. al. (2021); Cells; 2021 Mar 09 ; 10 (3) . doi:10.3390/cells10030598
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2 infected|CoV-2 infected|SARS-CoV-2-infected|COVID 19|Covid-19|COVID-19|COVID
MESH:C535733 der Substantia nigra pars compacta beim idiopathischen Parkinson-Syndrom.Structure
MESH:C537475 Mitochondrial complex I deficiency
MESH:C562385 iron dyshomeostasis
MESH:C566823 autosomal-dominant parkinsonism
MESH:D000068079 motor dysfunction|motor abnormalities
MESH:D000079225 Stress
MESH:D000080874 alpha-synucleinopathy|neurodegenerative synucleinopathies
MESH:D000370 hypogeusia
MESH:D000544 Alzheimer's disease|Alzheimer's disease brains
MESH:D000857 Hyposmia|hyposmia
MESH:D000860 hypoxia
MESH:D001102 viral infection|immunodeficiency virus-infected|immunodeficiency virus infection|viral infections
MESH:D001284 atrophy
MESH:D001480 extrapyramidal movement disorders
MESH:D001927 encephalopathy|Encephalopathy
MESH:D002534 hypoxic brain injury
MESH:D003141 LB disease
MESH:D003643 Death|neurodegenerative cell death
MESH:D003693 delirium
MESH:D003704 dementia
MESH:D003711 demyelinating disease
MESH:D003920 diabetes
MESH:D004409 akinesia
MESH:D004660 encephalitis
MESH:D004672 encephalitis B
MESH:D005911 gliosis
MESH:D006333 autonomic failure
MESH:D006432 iron storage disease
MESH:D006623 Verteilung von Noradrenalin
MESH:D007153 deficiency|immunodeficiency virus/HIV
MESH:D007239 Infections|Infection|infected|infection
MESH:D007249 inflammation|acute inflammation
MESH:D008569 memory T
MESH:D008659 metabolic diseases
MESH:D009069 Movement disorders
MESH:D009127 Hypokinetic-rigid movement disorders
MESH:D009336 Tumor necrosis
MESH:D009410 neuronal loss|SN neuronal loss|neuronal dysfunction|neuronal necrosis|neuronal cell death|SN neuronal degeneration|neuronal damage
MESH:D009421 neurological defects
MESH:D009422 neurological symptoms
MESH:D009443 Lewy neuritis
MESH:D009461 motor deficits|dysfunctional
MESH:D010300 Parkinson's Disease|idiopathic Parkinson's disease|PD brains|Parkinson's|PD|parkinsonsim and Parkinson's disease|Parkinson's disease|familial Parkinson's disease|Parkinson disease|PD-like injury|Lewy bodies of Parkinson disease|Parkinson Disease|neurodegenerative disorder Parkinson's disease|Idiopathic Parkinson's disease|Parkinson's disease-a multifactorial neurodegenerative disorder|autosomal dominant PD
MESH:D010301 encephalitis lethargica|encephalitic parkinsonism|postencephalitic parkinsonism|Encephalitis lethargica
MESH:D010302 Parkinson|parkinsonism
MESH:D010859 pigmentation
MESH:D012120 respiratory syndrome
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012162 degeneration via microgliosis
MESH:D012791 systems atrophies|degeneration in multiple systems atrophy
MESH:D013167 Spondyloarthritis
MESH:D013226 status epilepticus
MESH:D013651 mitochondriopathy, dysfunction of metal homeostasis
MESH:D014202 tremor
MESH:D015526 HIV dementia|Parkinsonism in HIV dementia|AIDS Dementia Complex
MESH:D015658 HIV-infected|HIV infection
MESH:D016464 lysosomal disorders
MESH:D018352 coronavirus disease
MESH:D018476 bradykinesia
MESH:D019636 neurodegenerative disorders|neurodegenerative maladies|Neurodegeneration|neurodegenerative diseases|neurodegeneration|SN neurodegeneration|neurodegenerative disorder
MESH:D020031 Epstein-Barr
MESH:D020258 neurotoxic|neurotoxicity
MESH:D020271 Neurological Diseases
MESH:D020521 strokes
MESH:D020734 parkinsonian deficits|autosomal recessive parkinsonism|parkinsonian brains|Parkinson-like syndrome|parkinsonian|parkinsonian brain
MESH:D020961 Lewy body disease|Lewy body diseases
MESH:D028361 mitochondrial deficits|mitochondrial dysfunction|Mitochondrial dysfunction
MESH:D030342 genetic defect|genetic abnormality|neuropathogenesis of the disorder
MESH:D034721 system dysfunction
MESH:D057165 proteostasis
MESH:D064420 cytotoxicity|toxicity
MESH:D065703 Neuronal Apoptosis
OMIM:256040 proteasomal dysfunction
 33895878
360" days post-injection (dpi), pathological alphaSyn conversion or clinical symptoms in transgenic TgM83+/- mice hemizygously expressing mutated (A53T) human alphaSyn (Prusiner et al. 2015, PNAS 112:E5308-E5317). To advance the assessment of possible alphaSynPD hazards by providing further data, we examined neuropathological and clinical effects upon i.c. transmission of brain, stomach wall and muscle tissue as well as blood from PD patients in TgM83+/- mice up to 612 dpi. This revealed a subtle, yet distinctive stimulation of localized alphaSyn aggregation in the somatodendritic compartment and dystrophic neurites of individual or focally clustered cerebral neurons after challenge with brain and stomach wall homogenates. No such effect was observed with transmitted blood or homogenized muscle tissue. The detected stimulation of alphaSyn aggregation was not accompanied by apparent motor impairments or overt neurological disease in TgM83+/- mice. Our study substantiated that transmitted alphaSynPD seeds, including those from the stomach wall, are able to propagate in new mammalian hosts. The consequences of such propagation and potential safeguards need to be further investigated.">Transmissible alpha-synuclein seeding activity in brain and stomach of patients with Parkinson's disease.
Thomzig A, et. al. (2021); Acta Neuropathol; 2021 Apr 24 . doi:10.1007/s00401-021-02312-4
MESH:C000598645 spheroid-like alphaSyn immunolabelling
MESH:C000657245 SARS-CoV-2-infected|Covid-19
MESH:C536778 SCD
MESH:C537412 substantia nigra reticulata
MESH:C564858 PK-resistant alphaSyn deposits
MESH:D000068079 motor impairments
MESH:D000079822 cerebral alphaSyn deposits
MESH:D000080874 synucleinopathy
MESH:D000544 Alzheimer's disease|Alzheimer's|Alzheimer's transfer|AD|Alzheimer disease
MESH:D001259 ataxia
MESH:D001284 atrophy
MESH:D001791 alphaSyn aggregation|hMW alphaSynPD aggregates|immunolabelling of alphaSynPD aggregates|cerebral alphaSyn aggregation|immunolabelling of hMW alphaSynPD aggregates|cerebral aggregation|subtle cerebral aggregation|alphaSynPD aggregates|aggregated alphaSynPD
MESH:D001796 cerebral protein aggregation
MESH:D001927 encephalopathies
MESH:D002543 intracerebral
MESH:D002544 ischemic stroke
MESH:D003643 died|death
MESH:D003704 dementia
MESH:D006402 cerebral protein aggregation disease|alphaSyn aggregation disease|alphaSyn aggregation diseases|protein aggregation diseases
MESH:D006623 Nachweis der Freiheit von einer Krankheit
MESH:D006816 HD
MESH:D007049 iatrogenic alphaSynPD
MESH:D007239 infection|infected
MESH:D009069 movement impairment|movement disorder
MESH:D009207 MJ
MESH:D009422 neurological impairments or disease|neurological impairments|neurological symptoms
MESH:D010243 paralysis
MESH:D010300 idiopathic Parkinson's disease|NBH Non-PD|PD brains|Parkinson disease|Parkinson s disease|PD|Parkinson's disease|neuropathological hallmark of Parkinson's disease
MESH:D010302 Parkinson|parkinsonism
MESH:D014202 tremor
MESH:D015431 weight loss
MESH:D016472 motor disease
MESH:D016657 cerebral amyloid angiopathy
MESH:D018376 apathy or abnormalities
MESH:D019636 nigrostriatal neurodegeneration|neurodegenerative protein aggregation disorders|neurodegenerative diseases|neurodegenerative protein aggregation disease|neurodegeneration|neurodegenerative disease
MESH:D020271 Neurological disease|neurological disease
MESH:D020961 Lewy body diseases
MESH:D053632 LB-linked alphaSynPD
MESH:D058225 dystrophic neurite|somatodendritic/dystrophic neurite|neuritic alphaSyn|dystrophic neurites
MESH:D060825 impairments
rs104893878
C/G
SNCA-AS1 644248 4:89835580 2
 32825327
Melatonin's Impact on Antioxidative and Anti-Inflammatory Reprogramming in Homeostasis and Disease.
Chitimus DM, et. al. (2020); Biomolecules; 2020 08 20 ; 10 (9) . doi:10.3390/biom10091211
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV-2 respiratory infection|COVID-19 Pneumonia|COVID 19|COVID-19
MESH:C564816 end-organ dysfunction
MESH:D000014 birth asphyxia
MESH:D000067329 Obesity-Related Metabolic Abnormalities
MESH:D000067877 autism spectrum disorders
MESH:D000070642 traumatic brain injury
MESH:D000077260 sleepiness
MESH:D000079225 Stress
MESH:D000081029 pulmonary arterial hypertension
MESH:D000208 acute injury|acute disease
MESH:D000275 Depression|depressive disorder
MESH:D000544 Alzheimer|Alzheimer's disease|Alzheimer's|Alzheimer's Disease Dementia|Alzheimer's Disease|AD
MESH:D000783 vascular disease
MESH:D000860 hypoxemia|hypoxia|Excitotoxicity and Hypoxia
MESH:D001145 malignant arrhythmias
MESH:D001157 Cord Occlusion|utero-ovarian artery occlusion
MESH:D001289 attention deficit-hyperactivity disorder|attention deficit
MESH:D001523 Behavioral Deficits
MESH:D001778 Coagulation Disorders|coagulopathy
MESH:D001929 brain edema
MESH:D001930 Hypoxic-Ischemic Brain Injury|brain injuries|brain injury|Ischemic Brain Injury
MESH:D001943 breast or ovarian cancer|Breast Cancer Tumors
MESH:D002311 dilated cardiomyopathy|Dilated Cardiomyopathy
MESH:D002312 ventricular hypertrophy
MESH:D002318 cardiovascular disorders|Cardiovascular Pathologies|cardiovascular and neurodegenerative diseases|cardiovascular death|Cardiovascular Benefits of Dietary Melatonin|cardiovascular diseases|Cardiovascular Homeostasis and Allostasis|cardiovascular disease|cardiovascular events
MESH:D002493 Central Nervous System Diseases
MESH:D002544 Ischemic-Stroke|Ischaemic Stroke
MESH:D002545 cerebral ischemic lesions|cerebral ischemia|Brain Ischemia|brain ischemia
MESH:D002561 cerebrovascular disease
MESH:D002908 Chronic Disease
MESH:D003072 cognitive impairment|cognitive deterioration|Cognitive Impairment and Alzheimer Disease
MESH:D003141 Homeostasis and Disease
MESH:D003324 ischemic heart disease|myocardial ischemia|coronary artery disease|Coronary Stiffness|Myocardial Ischemia
MESH:D003643 mortality|Death|death
MESH:D003693 Delirium|delirium
MESH:D003704 dementia
MESH:D003920 diabetes|diabetic|Diabetic
MESH:D003924 Type 2 Diabetes Mellitus
MESH:D004211 intravascular coagulation
MESH:D004244 dizziness
MESH:D004417 dyspnea
MESH:D004487 lung edema|Decreasies lung edema|swelling
MESH:D005315 Fetal Brain Injury
MESH:D005355 fibrosis|lung fibrosis|Fibrosis|Lung Fibrosis
MESH:D005767 Gastrointestinal Disorders
MESH:D006130 growth retardation
MESH:D006261 headache
MESH:D006331 Cardiac Ischemia-Reperfusion Injury|Cardiac Inflammatory Injury|Cardiac Syndrome|Heart Diseases|Cardiac Ischemia
MESH:D006333 Heart Failure|Chronic Heart Failure|heart failure
MESH:D006335 Heart Injury
MESH:D006528 Liver Cancer
MESH:D006816 Huntington's diseases|Huntington's Disease
MESH:D006948 hyperactivity
MESH:D006949 hyperlipidemia
MESH:D006970 somnolence
MESH:D006973 Hypertensive Disorders|Hypertension|hypertension|hypertensive|Hypertensive|Hypertension and Nitric Oxide Deficiency
MESH:D006976 pulmonary hypertension|Pulmonary Hypertensive|Pulmonary Hypertension
MESH:D007022 decreases pulmonary blood
MESH:D007029 hypothalamus
MESH:D007035 hypothermia|hypothermia plus melatonin
MESH:D007238 Infarct|infarct|Infarction
MESH:D007239 L-type infection|infection|infected
MESH:D007249 inflammation|hypoxic-ischemic inflammation|Inflammation|neuro-inflammation
MESH:D007319 insomnia|Insomnia
MESH:D007511 ischemia|Ischemia|Hypoxic ischemia|ischemic|ischemic conditions|hypoxic ischemia
MESH:D007589 HIE
MESH:D007635 Dendritic
MESH:D007752 babies born preterm|preterm babies|preterm labor
MESH:D008881 Migraine
MESH:D009202 myocardial injury|Myocardial Damage
MESH:D009203 Myocardial Infarction|myocaRdial Infarction|Myocardial infarction|MyocaRdial Infarction|myocardial infarction|Acute Myocardial Infarction
MESH:D009325 nausea
MESH:D009369 Cancer|cancer
MESH:D009410 ischemic neuronal loss|neuronal death|neuronal homeostasis|neuronal mitochondria|neuronal dysfunction
MESH:D009422 neurological disorders|Neurological Disorders
MESH:D009461 dysfunctional
MESH:D009765 obesity|obese|Obesity
MESH:D010195 Acute Pancreatitis
MESH:D010300 Parkinson's Disease|PD|PD disease|Parkinson's disease|Parkinson's|Parkinson's diseases
MESH:D010302 Parkinson
MESH:D010922 Chronic placental dysfunction
MESH:D011125 APC
MESH:D011225 Pre-Eclampsia|maternal preeclampsia or neonatal encephalopathy|Preeclampsia
MESH:D011595 agitation
MESH:D012128 acute respiratory distress syndrome|ARDS|respiratory distress
MESH:D012131 Respiratory failure|respiratory failure
MESH:D012140 respiratory diseases
MESH:D012640 seizures|Fitness
MESH:D012778 decreased bowel movements
MESH:D012893 sleep-wake disorder|sleep disorders
MESH:D013927 thrombosis
MESH:D014355 Chronic Chagas Disease
MESH:D014693 Ventricular Dyssynchrony
MESH:D014947 Injury
MESH:D015212 Inflammatory Bowel Disease
MESH:D015427 reperfusion injury|ischemia/reperfusion injury|ischemia reperfusion injury|Ischemia-Reperfusion Injury|ischemia-reperfusion injury|Reperfusion Injury|Ischemia and Reperfusion Injury to Brain
MESH:D015428 Myocardial Ischemia-Reperfusion Injury|Myocardial Ischemia/Reperfusion Injury
MESH:D016757 sudden cardiac death
MESH:D018235 Vascular Smooth Muscle Cell Dysfunction
MESH:D018805 Sepsis|sepsis
MESH:D019636 Neurodegeneration|neurodegenerative diseases|neurodegeneration process|neurodegeneration|Neurodegenerative Disorders|Degenerative Neurological Diseases|degenerative neurological disorders|neurodegenerative disorders|Neurodegenerative Disease|neurodegenerative disease of the brain
MESH:D020246 venous thrombosis
MESH:D020257 Left Ventricular Remodelling
MESH:D020258 neurotoxic aggregates|Neurotoxicity|neurotoxicity
MESH:D020271 Neurological diseases
MESH:D020521 stroke
MESH:D020925 hypoxic-ischemic injury|hypoxic-ischemic encephalopathy
MESH:D020964 hyperthermia-induced embryo death
MESH:D024821 Metabolic Syndrome|metabolic syndrome
MESH:D028361 mitochondrial dysfunction
MESH:D029424 chronic obstructive pulmonary disease|Chronic Obstructive Pulmonary Disease|COPD
MESH:D048909 diabetic complications
MESH:D050171 dyslipidemia
MESH:D050197 atherosclerotic|Atherosclerosis|atherosclerosis|atherosclerotic disease
MESH:D051271 ischemia symptoms
MESH:D054556 Venous Thromboembolism
MESH:D055370 lung injury|Lung Injury
MESH:D056486 hepatic carcinoma
MESH:D056784 white matter abnormalities
MESH:D056987 pulmonary vasoplegia
MESH:D058065 Diabetic Cardiomyopathy
MESH:D064420 cytotoxicity|toxicity|Toxicity
MESH:D065634 Cerebrospinal Fluid Deficiency of Melatonin
MESH:D066126 cardiotoxicity|Cardiotoxicity
 33803185
The Nigral Coup in Parkinson's Disease by alpha-Synuclein and Its Associated Rebels.
Sian-Hulsmann J, et. al. (2021); Cells; 2021 Mar 09 ; 10 (3) . doi:10.3390/cells10030598
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2 infected|CoV-2 infected|SARS-CoV-2-infected|COVID 19|Covid-19|COVID-19|COVID
MESH:C535733 der Substantia nigra pars compacta beim idiopathischen Parkinson-Syndrom.Structure
MESH:C537475 Mitochondrial complex I deficiency
MESH:C562385 iron dyshomeostasis
MESH:C566823 autosomal-dominant parkinsonism
MESH:D000068079 motor dysfunction|motor abnormalities
MESH:D000079225 Stress
MESH:D000080874 alpha-synucleinopathy|neurodegenerative synucleinopathies
MESH:D000370 hypogeusia
MESH:D000544 Alzheimer's disease|Alzheimer's disease brains
MESH:D000857 Hyposmia|hyposmia
MESH:D000860 hypoxia
MESH:D001102 viral infection|immunodeficiency virus-infected|immunodeficiency virus infection|viral infections
MESH:D001284 atrophy
MESH:D001480 extrapyramidal movement disorders
MESH:D001927 encephalopathy|Encephalopathy
MESH:D002534 hypoxic brain injury
MESH:D003141 LB disease
MESH:D003643 Death|neurodegenerative cell death
MESH:D003693 delirium
MESH:D003704 dementia
MESH:D003711 demyelinating disease
MESH:D003920 diabetes
MESH:D004409 akinesia
MESH:D004660 encephalitis
MESH:D004672 encephalitis B
MESH:D005911 gliosis
MESH:D006333 autonomic failure
MESH:D006432 iron storage disease
MESH:D006623 Verteilung von Noradrenalin
MESH:D007153 deficiency|immunodeficiency virus/HIV
MESH:D007239 Infections|Infection|infected|infection
MESH:D007249 inflammation|acute inflammation
MESH:D008569 memory T
MESH:D008659 metabolic diseases
MESH:D009069 Movement disorders
MESH:D009127 Hypokinetic-rigid movement disorders
MESH:D009336 Tumor necrosis
MESH:D009410 neuronal loss|SN neuronal loss|neuronal dysfunction|neuronal necrosis|neuronal cell death|SN neuronal degeneration|neuronal damage
MESH:D009421 neurological defects
MESH:D009422 neurological symptoms
MESH:D009443 Lewy neuritis
MESH:D009461 motor deficits|dysfunctional
MESH:D010300 Parkinson's Disease|idiopathic Parkinson's disease|PD brains|Parkinson's|PD|parkinsonsim and Parkinson's disease|Parkinson's disease|familial Parkinson's disease|Parkinson disease|PD-like injury|Lewy bodies of Parkinson disease|Parkinson Disease|neurodegenerative disorder Parkinson's disease|Idiopathic Parkinson's disease|Parkinson's disease-a multifactorial neurodegenerative disorder|autosomal dominant PD
MESH:D010301 encephalitis lethargica|encephalitic parkinsonism|postencephalitic parkinsonism|Encephalitis lethargica
MESH:D010302 Parkinson|parkinsonism
MESH:D010859 pigmentation
MESH:D012120 respiratory syndrome
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012162 degeneration via microgliosis
MESH:D012791 systems atrophies|degeneration in multiple systems atrophy
MESH:D013167 Spondyloarthritis
MESH:D013226 status epilepticus
MESH:D013651 mitochondriopathy, dysfunction of metal homeostasis
MESH:D014202 tremor
MESH:D015526 HIV dementia|Parkinsonism in HIV dementia|AIDS Dementia Complex
MESH:D015658 HIV-infected|HIV infection
MESH:D016464 lysosomal disorders
MESH:D018352 coronavirus disease
MESH:D018476 bradykinesia
MESH:D019636 neurodegenerative disorders|neurodegenerative maladies|Neurodegeneration|neurodegenerative diseases|neurodegeneration|SN neurodegeneration|neurodegenerative disorder
MESH:D020031 Epstein-Barr
MESH:D020258 neurotoxic|neurotoxicity
MESH:D020271 Neurological Diseases
MESH:D020521 strokes
MESH:D020734 parkinsonian deficits|autosomal recessive parkinsonism|parkinsonian brains|Parkinson-like syndrome|parkinsonian|parkinsonian brain
MESH:D020961 Lewy body disease|Lewy body diseases
MESH:D028361 mitochondrial deficits|mitochondrial dysfunction|Mitochondrial dysfunction
MESH:D030342 genetic defect|genetic abnormality|neuropathogenesis of the disorder
MESH:D034721 system dysfunction
MESH:D057165 proteostasis
MESH:D064420 cytotoxicity|toxicity
MESH:D065703 Neuronal Apoptosis
OMIM:256040 proteasomal dysfunction
rs1048943 Affx-11968489
T/C
CYP1A1 1543 15:74720644 1
 32936528
Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19).
Zubiaur P, et. al. (2020); Clin Transl Sci; 2020 Sep 16 . doi:10.1111/cts.12866
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|2019-nCoV acute respiratory disease|novel coronavirus disease|CoV-2 Infection|Coronavirus Disease 2019|Covid-19|COVID-19|COVID
MESH:C536362 Castleman's disease
MESH:C537372 Multicentric Castleman's disease
MESH:C538614 renal-cell carcinomas
MESH:C562393 cutaneous melanoma
MESH:D000067390 cold
MESH:D000070603 osteonecrosis of the femoral head
MESH:D000163 AIDS
MESH:D000275 depression
MESH:D000740 malarial anaemia
MESH:D000743 hemolytic anemia|haemolytic anaemias
MESH:D001007 social anxiety disorder|anxiety disorders
MESH:D001102 virus infection|viral infections
MESH:D001172 rheumatoid arthritis
MESH:D001201 ascites
MESH:D001249 asthma
MESH:D001327 autoimmune diseases
MESH:D001523 aggression
MESH:D002318 cardiovascular diseases
MESH:D003141 infectious|fibrotic diseases
MESH:D003324 coronary artery disease
MESH:D003371 cough
MESH:D003643 deaths|died
MESH:D003920 diabetes
MESH:D003928 diabetic nephropathy
MESH:D004417 shortness of breath
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D005955 G6PD deficient|deficient glucose-6-phosphate dehydrogenase|G6PD deficiency|glucose-6-phosphate dehydrogenase deficiency
MESH:D006333 heart failure
MESH:D006391 hemangiomas
MESH:D006461 hemolysis|haemolysis crisis
MESH:D006509 hepatitis B
MESH:D006526 hepatitis C virus (HCV) infections
MESH:D006973 hypertension
MESH:D007153 deficiency can easily|deficiency|G6PDH-deficient
MESH:D007239 infection
MESH:D007249 inflammation
MESH:D007565 jaundice
MESH:D007674 proteinuric renal disease
MESH:D007943 hairy-cell leukemia
MESH:D008175 lung cancer
MESH:D008228 non-Hodgkin lymphoma
MESH:D008232 lymphoproliferative disorder
MESH:D008288 malaria|malaria infection|Malaria
MESH:D009101 myeloma|multiple myeloma
MESH:D009102 multi-organ failure
MESH:D009103 multiple sclerosis
MESH:D009203 myocardial infarcted
MESH:D009336 tumor necrosis
MESH:D009771 obsessive-compulsive disorder
MESH:D010146 pain
MESH:D010300 Bechet's disease
MESH:D010493 pericarditis
MESH:D010505 familial Mediterranean fever|Familial Mediterranean fever|FMF
MESH:D011014 pneumonia
MESH:D011087 myelofibrosis and polycythemia vera
MESH:D011565 psoriasis
MESH:D012128 acute respiratory distress syndrome
MESH:D012140 respiratory diseases
MESH:D012141 respiratory infection
MESH:D012514 Kaposi's sarcoma
MESH:D015047 zoonotic
MESH:D015179 colorectal cancer
MESH:D015464 chronic myelogenous leukemia
MESH:D015658 HIV infection|HIV-1 infection|HIV infections
MESH:D016584 panic disorder
MESH:D016779 cerebral malaria
MESH:D017577 hyperproliferative cutaneous disorders
MESH:D018352 MERS|Coronavirus disease|human coronavirus infections|MERS zoonotic|Middle East respiratory syndrome
MESH:D018512 parasitemia
MESH:D018754 ventricular dysfunction
MESH:D018805 sepsis
MESH:D029424 chronic obstructive pulmonary disease
MESH:D030361 papillomavirus infections
MESH:D034701 cutaneous diseases
MESH:D040921 traumatic stress disorder
MESH:D055370 lung injuries
MESH:D060085 secondary kidney diseases
MESH:D063806 myalgia
MESH:D064420 toxicity
rs104895094
T/A,C
MEFV 4210 16:3243403 1
 33525390
Multifactorial Rare Diseases: Can Uncertainty Analysis Bring Added Value to the Search for Risk Factors and Etiopathogenesis?
Taruscio D, et. al. (2021); Medicina (Kaunas); 2021 Jan 28 ; 57 (2) . doi:10.3390/medicina57020119
MESH:C000657245 CoV-2 infection|SARS-CoV-2 infection|SARS-CoV-2 Infection|COVID-19
MESH:C537017 KD
MESH:D000013 congenital anomalies|Congenital Anomalies
MESH:D000014 birth defects|births plus fetal deaths
MESH:D000163 AIDS
MESH:D000686 amyloidosis
MESH:D000757 anencephaly
MESH:D001064 acute appendicitis
MESH:D003141 Infectious Diseases|infectious diseases
MESH:D003643 death
MESH:D003920 diabetes
MESH:D005184 neural tube defects|Neural tube defects
MESH:D005315 fetal anomaly
MESH:D005334 Familial Mediterreanean Fever|familial Mediterreanean fever|fever
MESH:D007249 inflammation
MESH:D007938 leukemia|childhood leukaemia
MESH:D008831 microcephaly
MESH:D009080 Kawasaki disease|Kawasaki Disease
MESH:D009369 tumor|tumors
MESH:D010300 Parkinson's disease
MESH:D010505 familial Mediterranean fever|Mediterranean Fever|FMF|Familial Mediterranean fever|Familial Mediterranean Fever
MESH:D011041 II poisoning
MESH:D012120 Acute Multisystem Inflammatory Syndrome
MESH:D012213 rheumatic fever|Acute Rheumatic Fever
MESH:D012480 Salmonellosis
MESH:D012700 diffuse serositis
MESH:D012772 Toxic Shock Syndrome|toxic shock syndrome
MESH:D015179 colorectal cancer
MESH:D015470 secondary acute leukemia|acute leukemia
MESH:D015658 HIV
MESH:D016142 holoprosencephaly
MESH:D035583 multifactorial rare diseases
MESH:D044882 glucose homeostasis
MESH:D054198 lymphoblastic leukemia
MESH:D056486 Hepatitis|hepatitis
MESH:D056587 Childhood Multisystem Inflammatory Syndrome
MESH:D056647 systemic vasculitis
MESH:D056660 painful periodic fever|autoinflammatory disease
MESH:D058729 arterial damage
MESH:D064420 toxicities
rs104895097
C/T
MEFV 4210 16:3243205 1
 33072117
Familial Mediterranean Fever and COVID-19: Friends or Foes?
Stella A, et. al. (2020); Front Immunol; 2020 ; 11 574593. doi:10.3389/fimmu.2020.574593
MESH:C000657245 COVID-19 Hyperinflammatory Syndrome|COVID-19 pneumonia|SARS-CoV-2 infection|COVID19|SARS-CoV-infected|novel coronavirus pneumonia|COvid-19|SARS-CoV-2 Viral Infection|COVID-19
MESH:C536227 leucopenia
MESH:D000370 ageusia
MESH:D000857 anosmia
MESH:D001102 Viral Infections|viral infection|virus infection|viral infections
MESH:D001171 Still's disease
MESH:D002318 Cardiovascular disease
MESH:D002637 chest pain
MESH:D002908 chronic diseases
MESH:D003141 infectious diseases
MESH:D003371 coughing
MESH:D003643 deaths
MESH:D004487 swelling
MESH:D005334 fever
MESH:D006073 gout
MESH:D007239 rhinovirus infection|infections|infected|infection
MESH:D007249 inflammation
MESH:D007938 acute leukaemia
MESH:D007964 leukocytosis
MESH:D008171 lung disease|lung damage
MESH:D008659 metabolic dysfunctions
MESH:D009205 myocarditis
MESH:D009369 cancers
MESH:D010146 pain
MESH:D010493 pericarditis
MESH:D010505 periodic syndrome|Familial Mediterranean Fever|FMF
MESH:D011014 pneumonia|pneumonitis
MESH:D012128 ARDS
MESH:D012817 gastrointestinal symptoms
MESH:D015047 zoonotic
MESH:D018352 coronavirus infections
MESH:D018771 arthralgia
MESH:D055370 lung injury
MESH:D055501 macrophage activation syndrome
MESH:D056660 autoinflammatory syndromes|hereditary periodic fever syndromes|inflammasomopathy (autoinflammatory disorder|autoinflammatory diseases
rs104895512
G/C
NLRP7 199713 19:54936313 1
 32698238
COVID-19 and hydatidiform mole.
Abbas AM, et. al. (2020); Am. J. Reprod. Immunol.; 2020 Jul 22 13310. doi:10.1111/aji.13310
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|2019 novel coronavirus pneumonia|coronavirus disease-2019|COVID-19|NCP
MESH:C536227 leucopenia|Leucopenia
MESH:D000014 uterine abnormalities, defects in the ova
MESH:D001102 viral infection|viral infections
MESH:D001327 autoimmune diseases
MESH:D002318 cardiovascular diseases
MESH:D003371 coughing
MESH:D003643 death
MESH:D004487 edematous swelling of the chorionic villi and trophoblastic hyperplasia
MESH:D006333 implantation failure
MESH:D006828 gestational trophoblastic diseases|Gestational trophoblastic disease|gestational trophoblastic disease
MESH:D007239 infections|infection|infected
MESH:D007249 inflammation
MESH:D007877 Legionella pneumophili
MESH:D008231 Lymphocytopenia|lymphopenia
MESH:D009102 multiple organ failure
MESH:D009336 tumour necrosis
MESH:D009361 cytotrophoblastic invasiveness
MESH:D011014 pneumonia
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 ARDS|acute respiratory distress syndrome|adult respiratory distress syndrome
MESH:D012141 respiratory tract infections
MESH:D014328 trophoblastic diseases
MESH:D015794 CHM
MESH:D016920 bacterial
MESH:D019214 overgrowth
MESH:D030361 papillomavirus (HPV) infection
MESH:D045169 severe acute respiratory syndrome
MESH:D051359 hemophagocytic lymphohistiocytosis
rs10490770 Affx-22367898
T/C
LOC107986083 107986083 3:45823240 3
 33593941
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals.
Zeberg H, et. al. (2021); Proc Natl Acad Sci U S A; 2021 Mar 02 ; 118 (9) . doi:10.1073/pnas.2026309118
MESH:C000657245 SARS-CoV-2 infection|Covid-19|COVID-19
MESH:D001102 viral infections
MESH:D003141 infectious disease|infectious diseases
MESH:D003643 Mortality|mortality
MESH:D004342 allergies
MESH:D006526 hepatitis C infections
MESH:D006527 Wilson
MESH:D007239 infections|infected|infection
MESH:D010146 pain
MESH:D012131 respiratory failure
MESH:D012859 Sjogren's syndrome
MESH:D016638 critical illness|critically ill
MESH:D045169 Severe acute respiratory syndrome
 33619490
Association of CXCR6 with COVID-19 severity: Delineating the host genetic factors in transcriptomic regulation.
Dai Y, et. al. (2021); bioRxiv; 2021 Feb 19 . doi:10.1101/2021.02.17.431554
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|Coronavirus Disease 2019|Covid-19|COVID-19
MESH:C564969 multi-organ damage
MESH:D000544 Alzheimer's disease
MESH:D003139 Common Complex Disease
MESH:D003141 infectious disease
MESH:D003424 Crohn's Disease
MESH:D003643 mortality|death
MESH:D007239 infected|infection
MESH:D007249 inflammation
MESH:D008175 Lung Carcinoma
MESH:D012128 acute respiratory distress syndrome
MESH:D012131 Respiratory Failure|respiratory failure
MESH:D016638 critical illness
 33758887
Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.
Nakanishi T, et. al. (2021); medRxiv; 2021 Mar 12 . doi:10.1101/2021.03.07.21252875
MESH:C000657245 covid-19|SARS-CoV-2 infection|COVID19-Host|COVID19|SARSCoV-2 infections|COVID GWAs|Covid|COVID19 death|SARS-Cov-2 infection|CoV-2 infection|Covid-19|COVID-19|COVID
MESH:C535509 LV
MESH:D000275 Depression
MESH:D001943 breast cancer|contralateral breast cancer|breast cancers
MESH:D002318 Cardiovascular complications|cardiovascular complications
MESH:D003324 coronary heart disease
MESH:D003643 mortality|Death|died|deaths|death
MESH:D003920 diabetes mellitus
MESH:D006333 heart failure
MESH:D006463 HUS
MESH:D007239 infection
MESH:D007249 inflammation
MESH:D009203 acute myocardial infarction|myocardial infarction
MESH:D009223 DM
MESH:D009369 High cancer|cancer
MESH:D009765 obesity
MESH:D010051 ovarian cancer
MESH:D011655 pulmonary embolism
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 Respiratory Failure|Respiratory failure|respiratory failure
MESH:D013927 thrombotic syndrome
MESH:D016638 critical illness
MESH:D017114 acute hepatic failure
MESH:D020246 deep venous thrombosis
MESH:D020521 stroke
MESH:D020936 Familial hypercholesterolaemia
MESH:D029424 chronic obstructive pulmonary disease|COPD
MESH:D050197 Atherosclerosis Society
MESH:D051436 chronic kidney disease
MESH:D054556 venous thromboembolism|Venous thromboembolism|VTE
MESH:D056486 hepatic injury|Hepatic injury
MESH:D058186 acute kidney injury|Kidney injury 1,095|Kidney injury
MESH:D058540 AIC
rs1049130
A/G
HLA-DQB1 3119 6:32662082 1
 32511533
The landscape of host genetic factors involved in infection to common viruses and SARS-CoV-2.
Kachuri L, et. al. (2020); medRxiv; 2020 May 30 . doi:10.1101/2020.05.01.20088054
MESH:C000657245 SARS-CoV-2 infection|COVID-19
MESH:C536260 pneumologie de Quebec
MESH:D000230 adenocarcinomas
MESH:D000544 Alzheimer|Alzheimer's disease|Alzheimer's Disease|Alzheimer disease
MESH:D001102 Viral Infections|Viral Diseases|viral infection|Viral Infection|viral infections
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma
MESH:D001327 autoimmune diseases
MESH:D001714 schizophrenia and bipolar disorder
MESH:D001749 bladder cancer
MESH:D002277 epithelial dysfunction
MESH:D002318 cardiovascular disease
MESH:D002446 celiac disease
MESH:D003139 Common Complex Disease
MESH:D003550 cystic fibrosis
MESH:D003920 diabetes
MESH:D003922 type I diabetes
MESH:D004342 hypersensitivity reactions
MESH:D004406 immunoglobulin A deficiency
MESH:D005909 glioblastoma
MESH:D005910 glioma
MESH:D006509 Hepatitis B
MESH:D007153 immunodeficiency
MESH:D007239 lytic infection|steps of the infection|infections|MCV infection|JCV infection|infection
MESH:D007968 JC polyomavirus infection
MESH:D008171 lung disease|lung eQTLs
MESH:D008175 lung cancer
MESH:D008223 lymphoma
MESH:D008545 melanoma
MESH:D009103 multiple sclerosis|Multiple Sclerosis
MESH:D009369 Cancer|tumor|malignancies|hematologic cancers|tumors|immunogenic tumors|cancer|cancers|tumour
MESH:D010031 ear infection
MESH:D010300 PD-1 blockade
MESH:D011014 pneumonia|lung inflammation
MESH:D012128 respiratory distress
MESH:D012559 Schizophrenia|schizophrenia GWAS|hallmark of schizophrenia|schizophrenia
MESH:D012878 skin cancer
MESH:D014947 injury
MESH:D015212 inflammatory bowel disease
MESH:D015266 Merkel cell carcinoma
MESH:D016393 B cell lymphoma
MESH:D017098 IgA deficiency
MESH:D017250 Norovirus infection
MESH:D018352 respiratory syndrome coronavirus infection
MESH:D019636 neurodegenerative diseases
MESH:D020031 Epstein-Barr virus-related lymphomas|EBV infection
MESH:D027601 neurotropic polyomavirus
MESH:D029424 airway disease
MESH:D030361 Papillomavirus
MESH:D054198 acute lymphoblastic leukemia
MESH:D055370 lung injury
MESH:D063646 carcinogenesis
rs1049728 Affx-5690328
G/C
RELA 5970 11:65653646 1
 33763088
Germline Genetic Variants of Viral Entry and Innate Immunity May Influence Susceptibility to SARS-CoV-2 Infection: Toward a Polygenic Risk Score for Risk Stratification.
Grolmusz VK, et. al. (2021); Front Immunol; 2021 ; 12 653489. doi:10.3389/fimmu.2021.653489
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2 Infection|Covid-19|COVID-19
MESH:D000071074 neonatal sepsis
MESH:D000072742 invasive fungal disease
MESH:D000077273 papillary thyroid carcinoma
MESH:D000152 acne vulgaris
MESH:D000292 pelvic inflammatory disease
MESH:D001015 takayasu arteritis
MESH:D001102 virus infection|viral infections
MESH:D001167 arteritis
MESH:D001168 arthritis
MESH:D001172 rheumatoid arthritis|RA
MESH:D001249 asthma|Asthma
MESH:D001281 atrial fibrillation
MESH:D001327 Autoimmune diseases|autoimmune diseases|Autoimmune disorders|autoimmune disorders
MESH:D001943 breast cancer
MESH:D001989 bronchiolitis obliterans syndrome
MESH:D002181 vulvovaginal candidiasis
MESH:D002294 squamous cell carcinoma|cervical squamous cell carcinoma
MESH:D002311 Dilated cardiomyopathy|DCM|dilated cardiomyopathy|hypertrophic and dilated cardiomyopathies
MESH:D002318 cardiovascular disorders|cardiovascular and metabolic diseases|Cardiovascular death|cardiovascular events
MESH:D002446 celiac disease
MESH:D002544 ischaemic stroke|ischemic stroke|Ischemic stroke
MESH:D002690 Chlamydia trachomatis infection
MESH:D002908 chronic diseases
MESH:D003110 colon
MESH:D003141 infectious diseases
MESH:D003324 coronary artery disease|Coronary artery disease N
MESH:D003371 dry cough
MESH:D003424 Crohn's disease
MESH:D003556 cystitis
MESH:D003586 cytomegalovirus infection|congenital cytomegalovirus (CMV) infection
MESH:D003643 mortality|death
MESH:D003920 diabetes|Diabetic retinopathy|diabetes mellitus
MESH:D003924 type 2 diabetes mellitus
MESH:D004417 dyspnea
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D005759 gastroenteritis
MESH:D005910 glioma
MESH:D006111 Graves' disease
MESH:D006509 HBV-infected|chronic HBV infection|hepatitis B|hepatitis B virus infection
MESH:D006526 HCV infection|hepatitis C virus infection|hepatitis C virus
MESH:D006528 hepatocellular carcinoma|liver cancer
MESH:D006689 Hodgkin lymphoma|hodgkin lymphoma
MESH:D006973 Hypertension|hypertension|hypertensive left ventricular hypertrophy
MESH:D007037 hypothyroidism
MESH:D007239 tuberculosis infection|CMV infection|infections|infected|infection
MESH:D007249 inflammation|Inflammation
MESH:D007319 initiation of the disease
MESH:D007674 IgA nephropathy|nephropathy
MESH:D008107 liver diseases
MESH:D008175 lung cancer
MESH:D008180 systemic lupus|lupus erythematosus|male systemic lupus erythematosus|systemic lupus erythematosus|SLE
MESH:D008181 lupus nephritis
MESH:D008193 Lyme disease
MESH:D008228 non-hodgkin's lymphoma|non-hodgkin lymphoma|non-Hodgkin lymphoma
MESH:D008288 malaria|malaria infection
MESH:D008545 melanoma|melanoma malignum
MESH:D008589 meningococcal
MESH:D008661 Inborn errors of type I
MESH:D008947 MCTD
MESH:D009059 mouth disease
MESH:D009102 sepsis-related organ failure
MESH:D009103 multiple sclerosis|Multiple sclerosis
MESH:D009336 tumour necrosis|tumor necrosis
MESH:D009369 malignant disorder|cancer|cancers|carcinoma|tumors
MESH:D009386 Neoplastic diseases|neoplastic diseases
MESH:D009765 obesity
MESH:D010003 osteoarthritis
MESH:D010031 otitis
MESH:D010300 's disease
MESH:D010518 periodontitis|aggressive periodontitis
MESH:D010859 pigmentation
MESH:D011014 pneumonia
MESH:D011471 advanced prostate cancer|prostate cancer
MESH:D011565 psoriasis|psoriasis vulgaris
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure
MESH:D012162 degeneration
MESH:D012164 retinopathy
MESH:D012409 rubella|rubella vaccination
MESH:D012507 sarcoidosis
MESH:D012559 Schizophrenia|schizophrenia
MESH:D012595 systemic sclerosis
MESH:D013167 ankylosing spondylitis
MESH:D013274 gastric cancer
MESH:D013700 giant cell arteritis
MESH:D013964 thyroid cancer
MESH:D014376 tuberculosis|tuberculosis disease
MESH:D014397 pulmonary tuberculosis
MESH:D015179 colorectal cancer|CRC
MESH:D015470 acute myeloid leukaemia|acute myeloid leukemia|AML
MESH:D015535 psoriatic arthritis
MESH:D015658 vaginosis in HIV-infected|HIV-1 infected|HIV infection|HIV-1 infected adolescents|HIV-1 infection|HIV infections
MESH:D016585 bacterial vaginosis
MESH:D016638 critical illness
MESH:D016920 bacterial
MESH:D017093 hepatic organ failure
MESH:D017359 preeclampsia and HELLP syndrome
MESH:D017379 Left ventricular hypertrophy
MESH:D018357 respiratory syncytial virus disease
MESH:D018442 marginal zone lymphoma
MESH:D018805 sepsis
MESH:D020521 stroke
MESH:D024821 Metabolic syndrome|metabolic syndrome
MESH:D030342 congenital CMV disease
MESH:D030361 papillomavirus-16 infection
MESH:D043183 irritable bowel syndrome
MESH:D049970 Graves' ophthalmopathy|ophthalmopathy
MESH:D050197 atherosclerotic
MESH:D054058 acute coronary syndrome|coronary syndrome
MESH:D054990 idiopathic pulmonary fibrosis
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D055732 cavitary pulmonary aspergillosis|pulmonary aspergillosis
MESH:D055744 invasive aspergillosis
MESH:D065632 chikungunya virus infection
rs1049807
A/G
CCL4 6351 17:36105270 1
 33246355
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.
Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
MESH:C000657245 coronavirus 2 infection|SARS-CoV-2 infection|coronavirus disease 2019|coronavirus (2019-nCoV) infections|COVID-19
MESH:D000077192 lung adenocarcinoma
MESH:D001281 atrial fibrillation
MESH:D001943 Breast cancer
MESH:D002318 cardiovascular diseases
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004487 oedema
MESH:D004646 emphysema
MESH:D005334 fever
MESH:D007239 infection|infected
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 lung damage
MESH:D008175 lung cancer
MESH:D009102 multiple organ failure|sepsis and organ failure
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012818 respiratory and gastrointestinal infections
MESH:D018352 coronavirus disease
MESH:D055370 lung injury|chronic lung disease
MESH:D055371 acute lung injury
MESH:D063806 muscle soreness
rs10503951 Affx-32083528
A/G
LOC105379364 105379364 8:33808162 1
 28951201
Genetic susceptibility to infectious diseases: Current status and future perspectives from genome-wide approaches.
Mozzi A, et. al. (2017); Infect. Genet. Evol.; 2017 Sep 22. doi:10.1016/j.meegid.2017.09.028
- HCHS|Republic of Tanzania|Romania|Kenia AC00600|candidaemia|Malawi HBB
MESH:C000656964 Aspergillus fumigatus infection
MESH:C000657245 SARS-CoV
MESH:C537418 Hepatitits C viruses
MESH:C565232 interleukin-12 deficiency
MESH:C567070 mycobacterial disease
MESH:D000152 Acne vulgaris
MESH:D000163 AIDS
MESH:D000544 Alzheimer abeta oligomer
MESH:D000740 anemia|anaemia|malarial anaemia|anaemia 2012 European
MESH:D001102 viral infection|viral infections
MESH:D001196 Ascaris infection
MESH:D001228 aspergillosis
MESH:D001327 autoimmunity|autoimmune diseases|autoimmune disorders
MESH:D001424 bacterial infections|bacterial infection
MESH:D001523 aggressive type of disease
MESH:D002177 vaginal candidiasis
MESH:D002340 carotid atherosclerosis
MESH:D002575 cervical carcinoma
MESH:D002583 cervical cancer
MESH:D002771 cholera infection
MESH:D003072 cognitive diseases
MESH:D003093 ulcerative colitis
MESH:D003141 infectious disease|infectious diseases
MESH:D003294 febrile seizures
MESH:D003424 Crohn's disease|granulomatous colitis|Crohn disease|Granulomatous colitis
MESH:D003428 nosocomial infections
MESH:D003449 cryoglobulinemia
MESH:D003731 caries Dental caries
MESH:D003920 diabetes
MESH:D003924 non-insulin-dependent diabetes mellitus|type 2 diabetes
MESH:D004067 chronic gastrointestinal tract disease
MESH:D004194 diarrhoeal disease|Diarrhoeal disease
MESH:D005076 rash
MESH:D005334 fever
MESH:D005368 filariasis
MESH:D005759 Gastroenteritis
MESH:D005767 gastrointestinal mucosa
MESH:D005955 G6PD deficiency
MESH:D006069 infection by Neisseria meningitidis
MESH:D006192 infection by Haemophilus
MESH:D006505 chronically-infected
MESH:D006509 HBV infection|chronic HBV infection|febrile seizures Hepatitis B|HBV chronic infection|HBV-infected|Hepatitis B|hepatitis B|hepatitis B virus infection
MESH:D006526 hepatitis C|hepatitis C infections|infectious diseases Viruses Hepatitis C virus|chronic HCV infection|immunodeficiency virus/hepatitis C virus-coinfected|HCV infection|impaired clearance of hepatitis C|HCV infections|hepatitis C virus infection
MESH:D006528 hepatocellular carcinoma
MESH:D007105 Complex disease
MESH:D007239 Helminth infections|infected Holsteins|IAV infection|infections|bovis infection|infection
MESH:D007249 cutaneous inflammation|inflammation|infection and autoimmunity/chronic inflammation
MESH:D007562 CJD
MESH:D007710 Klebsiella pneumonaie infection|Klebsiella pneumoniae infection
MESH:D007898 visceral Leishmaniasis|visceral leishmaniasis|Visceral leishmaniasis
MESH:D007918 MED30 Leprosy susceptiility Neisseria meningitidis|leprosy GWAS|CYLD Leprosy|leprosy
MESH:D007970 leukopenia
MESH:D008103 liver cirrhosis|liver fibrosis|CHC-induced liver cirrhosis|Liver fibrosis
MESH:D008105 primary biliary cirrhosis
MESH:D008107 liver disease
MESH:D008288 malaria|Gambia HBB Severe malaria
MESH:D008413 mastitis
MESH:D008581 meningitis|Diarrhoea and meningitis
MESH:D008589 meningococcal disease|Meningococcal Disease
MESH:D008661 enzyme deficiency
MESH:D009165 mycobacterial infections
MESH:D009369 cancer|cancers|tumor
MESH:D009396 Wilms' tumor|Indonesia and Russia WT1 Tuberculosis|WT1 Tuberculosis
MESH:D009503 neutropenia
MESH:D010272 parasitic infections|parasitic diseases|Parasitic infections
MESH:D010283 paratuberculosis infection|paratuberculosis|Johne's disease
MESH:D010518 Periodontitis|periodontitis
MESH:D010523 peripheral neuropathy
MESH:D011008 invasive pneumococcal infection|pneumococcal|invasive pneumococcal disease
MESH:D011552 aeruginosa pneumonia
MESH:D011565 psoriasis
MESH:D011654 pulmonary edema
MESH:D012131 respiratory syndrome
MESH:D012409 Rubella|rubella
MESH:D012480 Salmonella infection
MESH:D012507 sarcoidosis
MESH:D012640 fitness cost|seizures
MESH:D012772 septic shock
MESH:D012871 skin homeostasis
MESH:D013203 aureus infections|Staphylococcus aureus infection
MESH:D013921 thrombocytopenia
MESH:D014355 Chagas disease
MESH:D014376 Gambia and Ghana ASAP1 Tuberculosis|tuberculosis Beijing|Tuberculosis|tuberculosis
MESH:D014390 pulmonary TB or infected
MESH:D014397 pulmonary tuberculosis
MESH:D014657 vasculitis
MESH:D014901 chronic West Nile virus disease|WNV (West Nile virus) infection|Nile virus disease
MESH:D015212 inflammatory bowel disease
MESH:D015417 DSS
MESH:D015431 weight loss
MESH:D015535 psoriatic arthritis
MESH:D015658 HIV-infection Multiple|HIV-infected|Norwalk virus infection|HIV-1 virus|HIV-infection|HIV infection|HIV-1 infection|virus infection|HIV disease
MESH:D016470 bacteremia|pneumococcal bacteremia|occult pneumococcal bacteremia
MESH:D016779 G6PD deficiency on cerebral malaria|malaria and cerebral malaria|cerebral malaria
MESH:D017093 liver failure
MESH:D017096 prion disease
MESH:D017250 Norovirus infection|Norovirus infections
MESH:D018290 cervical intraepithelial neoplasia
MESH:D018805 septicaemia
MESH:D019142 Ebola hemorrhagic fever
MESH:D019595 Dengue shock syndrome|dengue shock syndrome
MESH:D019694 Chronic hepatitis B
MESH:D019698 hepatocellular carcinoma in chronic hepatitis C virus|cytopenia in chronic hepatitis C|Chronic hepatitis C|chronic hepatitis C|CHC
MESH:D019964 mood disorders
MESH:D025063 fucosyltransferase gene deficiency
MESH:D030361 Papillomavirus (HPV), Varicella Zooster virus|HPV infection
MESH:D050197 atherosclerosis
MESH:D055113 Chronic periodontitis
MESH:D060085 HIV co-infection
MESH:D063646 carcinogenic|Hepatocarcinogenesis
rs1050450 Affx-22405302
G/A
GPX1 2876 3:49357401 1
 32992282
Selenium and selenoproteins in viral infection with potential relevance to COVID-19.
Zhang J, et. al. (2020); Redox Biol; 2020 Sep 10 ; 37 101715. doi:10.1016/j.redox.2020.101715
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|COVID disease|SARS-CoV-2 infected|CoV-2 infection|SARS-COV-2 infection|Coronavirus Disease 2019|2019 novel coronavirus pneumonia|Covid-19|COVID-19|COVID|NCP
MESH:C535833 deficiency increases
MESH:C536166 Keshan disease|Keshan Disease|cardiomyopathy in Keshan Disease
MESH:C566454 thyroid hormone metabolism
MESH:D000079225 Stress
MESH:D000230 adenocarcinoma
MESH:D000783 vascular disease
MESH:D001102 a virally-infected|viral diseases|virus infections|viral infection|virus infection|Viral Infection|viral infections
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma
MESH:D001327 autoimmune diseases|Autoimmune Diseases
MESH:D001424 bacterial infections
MESH:D001714 bipolar disorders
MESH:D002544 ischemic stroke
MESH:D002908 chronic diseases|chronic disease
MESH:D003092 colitis
MESH:D003141 infectious diseases
MESH:D003324 coronary artery disease|coronary heart disease
MESH:D003398 CRS
MESH:D003643 mortality|Mortality|death
MESH:D003920 diabetes
MESH:D004417 breath
MESH:D004461 eclampsia
MESH:D005355 fibrosis
MESH:D006086 deficiency impairs host
MESH:D006333 Heart Failure
MESH:D006480 haemorrhagic fever|hemorrhagic fever
MESH:D006509 Hepatitis B
MESH:D006528 hepatocellular carcinoma|liver cancer|hepatitis B linked to liver cancer
MESH:D007153 Deficiency
MESH:D007154 immunological dysfunction|immune-system dysfunction|immunological diseases
MESH:D007239 rhinovirus infection|infection|infected
MESH:D007249 Deficiency on Inflammation|inflammation
MESH:D007938 lymphoblastic leukaemias
MESH:D008103 liver cirrhosis
MESH:D008104 Alcoholic Liver Cirrhosis
MESH:D008108 alcoholic liver disease
MESH:D008231 lymphopenia
MESH:D009202 cardiomyopathy
MESH:D009207 MJ
MESH:D009369 Cancer|cancer|cancers|neoplasia|tumour
MESH:D009765 obesity
MESH:D010190 pancreatic and renal cancer
MESH:D011014 pneumonia|lung inflammation
MESH:D011125 GS-SeH
MESH:D011225 Preeclampsia
MESH:D011471 Inflammation and prostate cancer|prostate cancer
MESH:D011696 Thrombocytopenic Purpura
MESH:D011697 Thrombocytopenia Purpura
MESH:D012128 Acute Respiratory Distress Syndrome|ARDS|acute respiratory distress syndrome
MESH:D012772 septic shock
MESH:D012818 respiratory symptoms
MESH:D013927 thrombus|thrombotic micronangiopathy
MESH:D013959 thyroid disorders|thyroid disease
MESH:D013967 autoimmune thyroid disease
MESH:D014376 tuberculosis
MESH:D014657 vasculitis
MESH:D015212 inflammatory bowel disease|IBD
MESH:D015470 AML
MESH:D015658 HIV-1 infected|HIV infection
MESH:D016393 B-cell lymphomas
MESH:D016638 critically-ill|critically ill|Critically Ill
MESH:D016736 Anti-Phospholipid Syndrome|Coagulopathy and Antiphospholipid Antibodies
MESH:D018352 MERS|Middle East Respiratory Syndrome|Coronavirus Disease
MESH:D018778 hantavirus infection
MESH:D018805 SIC|sepsis
MESH:D019698 Chronic Hepatitis C
MESH:D020275 GBS
MESH:D029424 chronic obstructive pulmonary disorder|chronic obstructive pulmonary disease|COPD
MESH:D034381 hearing loss
MESH:D050031 Hashimoto's Thyroiditis|Hashimoto's thyroiditis
MESH:D052016 mucositis
MESH:D057767 Kashin-Beck disease
MESH:D063646 carcinogenesis
MESH:D064420 cytotoxicity|toxicity|Toxicity
rs1050723
G/A
MIR6891 102465537 6:31355544 1
 33254234
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control.
Salpini R, et. al. (2021); J Antimicrob Chemother; 2021 01 19 ; 76 (2) 396-412. doi:10.1093/jac/dkaa444
MESH:C000657245 SARS-CoV-2 infection|COVID-19
MESH:D001102 viral infections
MESH:D003643 mortality|deaths
MESH:D007239 infections|infection|infected
MESH:D011014 pneumonia
rs1050828 Affx-34723402
C/T
G6PD 2539 X:154536002 2
 32936528
Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19).
Zubiaur P, et. al. (2020); Clin Transl Sci; 2020 Sep 16 . doi:10.1111/cts.12866
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|2019-nCoV acute respiratory disease|novel coronavirus disease|CoV-2 Infection|Coronavirus Disease 2019|Covid-19|COVID-19|COVID
MESH:C536362 Castleman's disease
MESH:C537372 Multicentric Castleman's disease
MESH:C538614 renal-cell carcinomas
MESH:C562393 cutaneous melanoma
MESH:D000067390 cold
MESH:D000070603 osteonecrosis of the femoral head
MESH:D000163 AIDS
MESH:D000275 depression
MESH:D000740 malarial anaemia
MESH:D000743 hemolytic anemia|haemolytic anaemias
MESH:D001007 social anxiety disorder|anxiety disorders
MESH:D001102 virus infection|viral infections
MESH:D001172 rheumatoid arthritis
MESH:D001201 ascites
MESH:D001249 asthma
MESH:D001327 autoimmune diseases
MESH:D001523 aggression
MESH:D002318 cardiovascular diseases
MESH:D003141 infectious|fibrotic diseases
MESH:D003324 coronary artery disease
MESH:D003371 cough
MESH:D003643 deaths|died
MESH:D003920 diabetes
MESH:D003928 diabetic nephropathy
MESH:D004417 shortness of breath
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D005955 G6PD deficient|deficient glucose-6-phosphate dehydrogenase|G6PD deficiency|glucose-6-phosphate dehydrogenase deficiency
MESH:D006333 heart failure
MESH:D006391 hemangiomas
MESH:D006461 hemolysis|haemolysis crisis
MESH:D006509 hepatitis B
MESH:D006526 hepatitis C virus (HCV) infections
MESH:D006973 hypertension
MESH:D007153 deficiency can easily|deficiency|G6PDH-deficient
MESH:D007239 infection
MESH:D007249 inflammation
MESH:D007565 jaundice
MESH:D007674 proteinuric renal disease
MESH:D007943 hairy-cell leukemia
MESH:D008175 lung cancer
MESH:D008228 non-Hodgkin lymphoma
MESH:D008232 lymphoproliferative disorder
MESH:D008288 malaria|malaria infection|Malaria
MESH:D009101 myeloma|multiple myeloma
MESH:D009102 multi-organ failure
MESH:D009103 multiple sclerosis
MESH:D009203 myocardial infarcted
MESH:D009336 tumor necrosis
MESH:D009771 obsessive-compulsive disorder
MESH:D010146 pain
MESH:D010300 Bechet's disease
MESH:D010493 pericarditis
MESH:D010505 familial Mediterranean fever|Familial Mediterranean fever|FMF
MESH:D011014 pneumonia
MESH:D011087 myelofibrosis and polycythemia vera
MESH:D011565 psoriasis
MESH:D012128 acute respiratory distress syndrome
MESH:D012140 respiratory diseases
MESH:D012141 respiratory infection
MESH:D012514 Kaposi's sarcoma
MESH:D015047 zoonotic
MESH:D015179 colorectal cancer
MESH:D015464 chronic myelogenous leukemia
MESH:D015658 HIV infection|HIV-1 infection|HIV infections
MESH:D016584 panic disorder
MESH:D016779 cerebral malaria
MESH:D017577 hyperproliferative cutaneous disorders
MESH:D018352 MERS|Coronavirus disease|human coronavirus infections|MERS zoonotic|Middle East respiratory syndrome
MESH:D018512 parasitemia
MESH:D018754 ventricular dysfunction
MESH:D018805 sepsis
MESH:D029424 chronic obstructive pulmonary disease
MESH:D030361 papillomavirus infections
MESH:D034701 cutaneous diseases
MESH:D040921 traumatic stress disorder
MESH:D055370 lung injuries
MESH:D060085 secondary kidney diseases
MESH:D063806 myalgia
MESH:D064420 toxicity
 33205496
Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment.
Al-Eitan LN, et. al. (2020); Rev Med Virol; 2020 Nov 17 2194. doi:10.1002/rmv.2194
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|Coronavirus disease 2019|novel coronavirus pneumonia|SARS-CoV-2 infections|CoV-2 infection|coronavirus disease-2019|Covid-19|COVID-19|Covid 19 pneumonia
MESH:D000072658 NSTEMI
MESH:D000740 anemia|anaemia
MESH:D000743 Haemolytic anaemia|hemolytic anemia
MESH:D001102 viral diseases|viral infection
MESH:D001172 rheumatoid arthritis
MESH:D001327 autoimmune disease|autoimmune diseases
MESH:D001778 coagulopathy|coagulation
MESH:D002318 cardiovascular disease|cardiovascular diseases
MESH:D002544 ischemic stroke
MESH:D003371 coughing
MESH:D003643 mortality|deaths|mortalities|death
MESH:D003920 diabetes|diabetic
MESH:D003924 type-2 diabetes mellitus
MESH:D005334 fever
MESH:D006461 haemolysis
MESH:D006509 hepatitis B virus|hepatitis B HBeAg|hepatitis B|hepatitis B virus infection
MESH:D006526 thrombocytopenia in hepatitis C|HCV-infected|HCV
MESH:D006973 hypertension|hypertensive
MESH:D007153 immunodeficiency virus
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D008175 lung tumor
MESH:D008179 chronic discoid lupus erythematosus
MESH:D008180 systemic lupus erythematosus
MESH:D008288 malaria|malaria to autoimmunity
MESH:D009203 myocardial infarction
MESH:D009336 tumour necrosis
MESH:D010300 PD
MESH:D011014 pneumonia|lung inflammation
MESH:D012128 acute respiratory distress syndrome
MESH:D012131 lung failure
MESH:D012140 respiratory disease
MESH:D012141 lung infections|respiratory infections
MESH:D012216 rheumatic
MESH:D013921 thrombocytopenia
MESH:D015047 zoonotic
MESH:D015658 HIV-infected|HIV
MESH:D017093 decreased hepatic midazolam metabolism
MESH:D018352 coronavirus infection|Middle East Respiratory Syndrome|middle east respiratory syndrome|Middle East respiratory syndrome
MESH:D019698 chronic hepatitis C
MESH:D024821 metabolic syndrome
MESH:D052439 lipid toxicity
MESH:D054058 acute coronary syndrome|coronary syndrome
MESH:D055370 lung injury
MESH:D058186 acute renal failure
MESH:D063806 muscle pain
MESH:D064420 toxicity
rs1050829
T/A,C
G6PD 2539 X:154535277 2
 32936528
Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19).
Zubiaur P, et. al. (2020); Clin Transl Sci; 2020 Sep 16 . doi:10.1111/cts.12866
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|2019-nCoV acute respiratory disease|novel coronavirus disease|CoV-2 Infection|Coronavirus Disease 2019|Covid-19|COVID-19|COVID
MESH:C536362 Castleman's disease
MESH:C537372 Multicentric Castleman's disease
MESH:C538614 renal-cell carcinomas
MESH:C562393 cutaneous melanoma
MESH:D000067390 cold
MESH:D000070603 osteonecrosis of the femoral head
MESH:D000163 AIDS
MESH:D000275 depression
MESH:D000740 malarial anaemia
MESH:D000743 hemolytic anemia|haemolytic anaemias
MESH:D001007 social anxiety disorder|anxiety disorders
MESH:D001102 virus infection|viral infections
MESH:D001172 rheumatoid arthritis
MESH:D001201 ascites
MESH:D001249 asthma
MESH:D001327 autoimmune diseases
MESH:D001523 aggression
MESH:D002318 cardiovascular diseases
MESH:D003141 infectious|fibrotic diseases
MESH:D003324 coronary artery disease
MESH:D003371 cough
MESH:D003643 deaths|died
MESH:D003920 diabetes
MESH:D003928 diabetic nephropathy
MESH:D004417 shortness of breath
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D005955 G6PD deficient|deficient glucose-6-phosphate dehydrogenase|G6PD deficiency|glucose-6-phosphate dehydrogenase deficiency
MESH:D006333 heart failure
MESH:D006391 hemangiomas
MESH:D006461 hemolysis|haemolysis crisis
MESH:D006509 hepatitis B
MESH:D006526 hepatitis C virus (HCV) infections
MESH:D006973 hypertension
MESH:D007153 deficiency can easily|deficiency|G6PDH-deficient
MESH:D007239 infection
MESH:D007249 inflammation
MESH:D007565 jaundice
MESH:D007674 proteinuric renal disease
MESH:D007943 hairy-cell leukemia
MESH:D008175 lung cancer
MESH:D008228 non-Hodgkin lymphoma
MESH:D008232 lymphoproliferative disorder
MESH:D008288 malaria|malaria infection|Malaria
MESH:D009101 myeloma|multiple myeloma
MESH:D009102 multi-organ failure
MESH:D009103 multiple sclerosis
MESH:D009203 myocardial infarcted
MESH:D009336 tumor necrosis
MESH:D009771 obsessive-compulsive disorder
MESH:D010146 pain
MESH:D010300 Bechet's disease
MESH:D010493 pericarditis
MESH:D010505 familial Mediterranean fever|Familial Mediterranean fever|FMF
MESH:D011014 pneumonia
MESH:D011087 myelofibrosis and polycythemia vera
MESH:D011565 psoriasis
MESH:D012128 acute respiratory distress syndrome
MESH:D012140 respiratory diseases
MESH:D012141 respiratory infection
MESH:D012514 Kaposi's sarcoma
MESH:D015047 zoonotic
MESH:D015179 colorectal cancer
MESH:D015464 chronic myelogenous leukemia
MESH:D015658 HIV infection|HIV-1 infection|HIV infections
MESH:D016584 panic disorder
MESH:D016779 cerebral malaria
MESH:D017577 hyperproliferative cutaneous disorders
MESH:D018352 MERS|Coronavirus disease|human coronavirus infections|MERS zoonotic|Middle East respiratory syndrome
MESH:D018512 parasitemia
MESH:D018754 ventricular dysfunction
MESH:D018805 sepsis
MESH:D029424 chronic obstructive pulmonary disease
MESH:D030361 papillomavirus infections
MESH:D034701 cutaneous diseases
MESH:D040921 traumatic stress disorder
MESH:D055370 lung injuries
MESH:D060085 secondary kidney diseases
MESH:D063806 myalgia
MESH:D064420 toxicity
 33205496
Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment.
Al-Eitan LN, et. al. (2020); Rev Med Virol; 2020 Nov 17 2194. doi:10.1002/rmv.2194
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|Coronavirus disease 2019|novel coronavirus pneumonia|SARS-CoV-2 infections|CoV-2 infection|coronavirus disease-2019|Covid-19|COVID-19|Covid 19 pneumonia
MESH:D000072658 NSTEMI
MESH:D000740 anemia|anaemia
MESH:D000743 Haemolytic anaemia|hemolytic anemia
MESH:D001102 viral diseases|viral infection
MESH:D001172 rheumatoid arthritis
MESH:D001327 autoimmune disease|autoimmune diseases
MESH:D001778 coagulopathy|coagulation
MESH:D002318 cardiovascular disease|cardiovascular diseases
MESH:D002544 ischemic stroke
MESH:D003371 coughing
MESH:D003643 mortality|deaths|mortalities|death
MESH:D003920 diabetes|diabetic
MESH:D003924 type-2 diabetes mellitus
MESH:D005334 fever
MESH:D006461 haemolysis
MESH:D006509 hepatitis B virus|hepatitis B HBeAg|hepatitis B|hepatitis B virus infection
MESH:D006526 thrombocytopenia in hepatitis C|HCV-infected|HCV
MESH:D006973 hypertension|hypertensive
MESH:D007153 immunodeficiency virus
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D008175 lung tumor
MESH:D008179 chronic discoid lupus erythematosus
MESH:D008180 systemic lupus erythematosus
MESH:D008288 malaria|malaria to autoimmunity
MESH:D009203 myocardial infarction
MESH:D009336 tumour necrosis
MESH:D010300 PD
MESH:D011014 pneumonia|lung inflammation
MESH:D012128 acute respiratory distress syndrome
MESH:D012131 lung failure
MESH:D012140 respiratory disease
MESH:D012141 lung infections|respiratory infections
MESH:D012216 rheumatic
MESH:D013921 thrombocytopenia
MESH:D015047 zoonotic
MESH:D015658 HIV-infected|HIV
MESH:D017093 decreased hepatic midazolam metabolism
MESH:D018352 coronavirus infection|Middle East Respiratory Syndrome|middle east respiratory syndrome|Middle East respiratory syndrome
MESH:D019698 chronic hepatitis C
MESH:D024821 metabolic syndrome
MESH:D052439 lipid toxicity
MESH:D054058 acute coronary syndrome|coronary syndrome
MESH:D055370 lung injury
MESH:D058186 acute renal failure
MESH:D063806 muscle pain
MESH:D064420 toxicity
rs1051042
G/C,T
OAS1 4938 12:112919432 1
 21638280
2'-5' oligoadenylate synthetase 1 polymorphism is associated with prostate cancer.
Mandal S, et. al. (2011); Cancer; 2011 Dec 15; 117(24) 5509-18. doi:10.1002/cncr.26219
MESH:C000657245 SARS-CoV infection
MESH:C537243 hereditary prostate cancer
MESH:C538184 AFD
MESH:C565201 sporadic aggressive prostate carcinoma
MESH:D001102 viral infection
MESH:D003920 diabetes
MESH:D003922 sclerosis and type I diabetes|Type 1 diabetes
MESH:D006323 growth arrest
MESH:D006526 hepatitis C virus infection
MESH:D007239 infections|infection
MESH:D008103 OAS-1 determines liver fibrosis
MESH:D009103 multiple sclerosis
MESH:D009369 Cancer|KU Cancer|cancer|tumor|cancers|Cancers
MESH:D011471 prostate cancer|Prostate cancer|prostate cancer disease|Prostate Cancer|sporadic prostate cancer
MESH:D012410 congenital rubella virus infection
MESH:D012598 sclerosis
MESH:D014901 West Nile virus infection
MESH:D018357 respiratory syncytial virus infection
MESH:D020022
rs10514906
A/T
SMIM15-AS1 101928630 5:61178754 1
 33791744
The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: analysis of high-throughput genetic, epigenetic, and gene expression studies.
Malato J, et. al. (2021); medRxiv; 2021 Mar 24 . doi:10.1101/2021.03.23.21254175
MESH:C000657245 2019 Coronavirus Disease|SARS-CoV-2 pneumonia|Coronavirus Disease 2019|Coronavirus disease 2019|SARS-CoV-2 infections|Covid-19|COVID-19
MESH:D001102 viral infections
MESH:D001145 arrythmia
MESH:D001249 asthma
MESH:D001327 autoimmune disease
MESH:D002318 cardiovascular dysfunctions|cardiovascular diseases
MESH:D002908 chronic disease
MESH:D003643 mortality
MESH:D003920 diabetes mellitus
MESH:D005221 Q fever fatigue syndrome|fatigue|fatigue syndrome|Fatigue Syndrome
MESH:D006973 hypertension
MESH:D007153 immunodeficiencies
MESH:D007154 Immunological abnormalities
MESH:D007239 Infection|Infections|Infected|CFS infected|infections|infection|infected
MESH:D007249 inflammation
MESH:D008231 lymphopenia
MESH:D008659 metabolic dysfunction
MESH:D009103 Multiple Sclerosis
MESH:D009369 cancer
MESH:D009461 dysfunctions
MESH:D009765 obesity
MESH:D012140 chronic obstructive respiratory disease
MESH:D012141 respiratory infections
MESH:D012507 sarcoidosis
MESH:D015673 Immunologic abnormalities in chronic fatigue syndrome|adolescent chronic fatigue syndrome|chronic fatigue syndrome|myalgic encephalomyelitis|Myalgic encephalomyelitis/Chronic Fatigue Syndrome|sclerosis and chronic fatigue syndrome|myalgic encephalomyelitis/chronic fatigue syndrome|Myalgic encephalomyelitis/chronic fatigue syndrome|Chronic Fatigue Syndrome|Myalgic Encephalomyelitis|fatigue-immune dysfunction syndrome|Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
MESH:D016638 critically ill
MESH:D018352 MERS|Middle East Respiratory Syndrome Coronavirus Attachment|Middle East Respiratory Syndrome|middle east respiratory syndrome
MESH:D020271 neurological diseases
MESH:D029424 COPD
MESH:D043183 irritable bowel syndrome
MESH:D052456 hypo-responsive
MESH:D054971 orthostatic intolerance
rs10518270
A/G,T
LOC105372262 105372262 19:7716549 2
 33133166
Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis.
Smatti MK, et. al. (2020); Front Genet; 2020 ; 11 578523. doi:10.3389/fgene.2020.578523
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|SARS-CoV-1 infected|SARS-CoV-infected|SARS-CoV-2 infections|SARS-CoV-1 infection|CoV-2 infections|COVID-19
MESH:C538098 Paget's disease
MESH:D001102 viral infections
MESH:D001281 AF
MESH:D003141 infectious diseases
MESH:D003643 mortality|death
MESH:D006509 hepatitis B|hepatitis B virus infection
MESH:D007239 Infection|infections|infection
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012141 respiratory infections
MESH:D015211 CHR
MESH:D018352 SARS-coronavirus-infected
MESH:D045169 severe acute respiratory syndrome|SARS illness
 33934196
Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection.
Hashemi SMA, et. al. (2021); Arch Virol; 2021 May 02 . doi:10.1007/s00705-021-05070-6
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV infection|COVID19|SARS-CoV-2 infections|novel coronavirus pneumonia|CoV-2 infection|novel coronavirus infections|SARS-CoV-2-infected|COVID-19|new coronavirus disease|SARS-CoV-1 infection Itoyama|Coronavirus disease 2019|2019 infection|SARS-CoV-1 infection outcome Patarcic|SARS-CoV-1 infection|Covid-19|coronavirus disease-2019
MESH:C535882 Johnson L
MESH:C536174 panbronchiolitis
MESH:C538614 renal cell carcinoma
MESH:C564969 multi-organ disease
MESH:C567355 immunodeficiency virus-mediated syncytia
MESH:D000544 Alzheimer's disease|Alzheimer disease
MESH:D000860 hypoxemia|hypoxia
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001424 bacterial infections
MESH:D001847 bone homeostasis
MESH:D001943 breast cancer
MESH:D002318 cardiovascular disease|cardiovascular systems|cardiovascular diseases
MESH:D002537 atherosclerotic cerebral infarction
MESH:D002544 acute cerebral infarction
MESH:D002908 rhinovirus illness
MESH:D003141 atherothrombotic disease|infectious diseases
MESH:D003428 nosocomial infection
MESH:D003643 mortality|deaths|mortalities|death|mortal
MESH:D003920 diabetes|diabetes mellitus
MESH:D003924 type 2 diabetes|type 2 diabetes mellitus
MESH:D004194 multiple diseases and disorders|numerous diseases and disorders
MESH:D004487 alveolar edema
MESH:D004646 emphysema
MESH:D004675 tick-borne encephalitis
MESH:D005355 fibrosis
MESH:D005921 glomerulosclerosis
MESH:D006331 congenital heart disease
MESH:D006333 heart failure
MESH:D006461 hemolysis
MESH:D006509 hepatitis B virus infection|hepatitis B
MESH:D006526 HCV infection|hepatitis C virus (HCV) infection|hepatitis C virus infection|hepatitis C viral infection
MESH:D006973 hypertension|hypertensive
MESH:D007239 Decreased infection|infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 Collapsing glomerulopathy|kidney disease|nondiabetic nephropathy|glomerulopathy
MESH:D008103 hepatic fibrosis
MESH:D008171 pulmonary damage|lung disease|lung damage
MESH:D008288 malaria parasites
MESH:D008545 melanoma|malignant melanoma
MESH:D008659 metabolic disorders
MESH:D008661 Inborn errors of type I
MESH:D009103 multiple sclerosis
MESH:D009336 tumour necrosis
MESH:D009362 metastasis of tumors
MESH:D009369 cancerous|cancer|cancers|tumor|carcinoma
MESH:D009393 nephritis
MESH:D010051 ovaries
MESH:D010190 invasiveness of pancreatic cancer
MESH:D010300 PD
MESH:D011014 pneumonia|lung inflammation
MESH:D011471 prostate cancer metastasis|NCI-H660 prostate cancer|prostate cancer|aggressive prostate cancer|sporadic prostate cancer
MESH:D011565 psoriasis
MESH:D011654 pulmonary edema
MESH:D011658 pulmonary fibrosis
MESH:D011660 hypoxaemic cor pulmonale
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome|ARDS|adult respiratory distress syndrome
MESH:D012131 respiratory failure|pulmonary failure
MESH:D012140 chronic respiratory disease|respiratory disease
MESH:D012141 respiratory viruses infections|upper respiratory tract infections
MESH:D012598 sclerosis
MESH:D012769 shock
MESH:D012871 skin diseases
MESH:D013927 thrombotic
MESH:D015140 vascular dementia
MESH:D015179 colorectal cancer
MESH:D015619 respiratory system edema
MESH:D015658 HIV infection|HIV-1 infection
MESH:D016638 critical illness|critically ill
MESH:D018352 MERS-CoV infection|respiratory syndrome coronavirus infection|coronavirus disease|SARS coronavirus infection|CoV-1 infection|coronavirus infection|Coronavirus infection|Middle East respiratory syndrome-coronavirus infection
MESH:D019698 chronic hepatitis C virus infection
MESH:D020258 neurotoxicity
MESH:D045169 severe acute respiratory syndrome|SARS infection
MESH:D050197 atherosclerotic|atherosclerosis|atherosclerotic lesions
MESH:D051436 chronic kidney disease
MESH:D054058 acute coronary syndrome
MESH:D054990 idiopathic pulmonary fibrosis
MESH:D055370 lung injury
MESH:D055371 acute lung failure|acute lung injury
MESH:D058186 Acute kidney injury
MESH:D059446 asplenia
rs1051868 Affx-4048547
G/A
CLCC1 23155 1:108930151 1
 33791744
The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: analysis of high-throughput genetic, epigenetic, and gene expression studies.
Malato J, et. al. (2021); medRxiv; 2021 Mar 24 . doi:10.1101/2021.03.23.21254175
MESH:C000657245 2019 Coronavirus Disease|SARS-CoV-2 pneumonia|Coronavirus Disease 2019|Coronavirus disease 2019|SARS-CoV-2 infections|Covid-19|COVID-19
MESH:D001102 viral infections
MESH:D001145 arrythmia
MESH:D001249 asthma
MESH:D001327 autoimmune disease
MESH:D002318 cardiovascular dysfunctions|cardiovascular diseases
MESH:D002908 chronic disease
MESH:D003643 mortality
MESH:D003920 diabetes mellitus
MESH:D005221 Q fever fatigue syndrome|fatigue|fatigue syndrome|Fatigue Syndrome
MESH:D006973 hypertension
MESH:D007153 immunodeficiencies
MESH:D007154 Immunological abnormalities
MESH:D007239 Infection|Infections|Infected|CFS infected|infections|infection|infected
MESH:D007249 inflammation
MESH:D008231 lymphopenia
MESH:D008659 metabolic dysfunction
MESH:D009103 Multiple Sclerosis
MESH:D009369 cancer
MESH:D009461 dysfunctions
MESH:D009765 obesity
MESH:D012140 chronic obstructive respiratory disease
MESH:D012141 respiratory infections
MESH:D012507 sarcoidosis
MESH:D015673 Immunologic abnormalities in chronic fatigue syndrome|adolescent chronic fatigue syndrome|chronic fatigue syndrome|myalgic encephalomyelitis|Myalgic encephalomyelitis/Chronic Fatigue Syndrome|sclerosis and chronic fatigue syndrome|myalgic encephalomyelitis/chronic fatigue syndrome|Myalgic encephalomyelitis/chronic fatigue syndrome|Chronic Fatigue Syndrome|Myalgic Encephalomyelitis|fatigue-immune dysfunction syndrome|Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
MESH:D016638 critically ill
MESH:D018352 MERS|Middle East Respiratory Syndrome Coronavirus Attachment|Middle East Respiratory Syndrome|middle east respiratory syndrome
MESH:D020271 neurological diseases
MESH:D029424 COPD
MESH:D043183 irritable bowel syndrome
MESH:D052456 hypo-responsive
MESH:D054971 orthostatic intolerance
rs1052746182 Affx-446875244
T/G
ACE2 59272 X:15564208 2
 32938937
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.
Sorokina M, et. al. (2020); Sci Data; 2020 09 16 ; 7 (1) 309. doi:10.1038/s41597-020-00652-6
MESH:C000657245 SARS-CoV-2 infection|Novel Coronavirus-Infected Pneumonia|COVID-19
MESH:C536528 vdW-van der
MESH:C564120 000,000 infections
MESH:D002318 cardiovascular disease
MESH:D003371 dry cough
MESH:D005221 tiredness
MESH:D005334 fever
MESH:D007239 infected
MESH:D009369 Cancer|cancer
MESH:D011014 pneumonia
MESH:D018352 coronavirus infections
 33195397
Drug Weaponry to Fight Against SARS-CoV-2.
Cabezón E, et. al. (2020); Front Mol Biosci; 2020 ; 7 204. doi:10.3389/fmolb.2020.00204
MESH:C000657245 SARS-CoV-2 infected|coronavirus disease 2019|SARS-CoV-2 infection|Covid-19|COVID-19|coronavirus Disease 2019
MESH:D001102 virus infection|viral infection
MESH:D001172 rheumatoid arthritis
MESH:D002318 Cardiovascular disease
MESH:D003643 mortality of the disease|mortality|death
MESH:D006973 hypertension
MESH:D007239 Infected|infected|infection|MERSCoV infection
MESH:D007674 embryonic kidneys
MESH:D009102 multi-organ failure
MESH:D011014 pneumonia
MESH:D012140 respiratory diseases
MESH:D018352 MERS-CoV infections|coronavirus infection|SARS coronavirus infection|Middle East Respiratory Syndrome|coronavirus tropism
MESH:D019698 chronic hepatitis C
MESH:D045169 Severe Acute Respiratory Syndrome
rs1052992527
A/G
APC 324 5:112707605 1
 33907749
Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19.
Roy Wong LY, et. al. (2021); bioRxiv; 2021 Apr 21 . doi:10.1101/2021.04.20.440676
MESH:C000657245 SARS-CoV-2 infection|Coronavirus disease 2019|SARS-CoV-infected|CoV-2 infection|SARS-CoV-2 infected|SARS-CoV-2-infected|Covid-19|SARS-CoV-2 Infection|COVID-19|acute respiratory syndrome-CoV infection
MESH:D000783 pulmonary vascular thrombi
MESH:D000857 anosmia
MESH:D001249 asthma|allergic asthma
MESH:D003643 mortality|Mortality|died|death
MESH:D004194 Damage and Lethal Disease
MESH:D004342 allergic disorders
MESH:D004487 Edema|alveolar edema|edema
MESH:D005598 pathological disease
MESH:D007239 Infection|Infected|infections|infection|infected
MESH:D007249 lymphoid inflammation|inflammation
MESH:D008171 lung lesion
MESH:D008231 Lymphopenia
MESH:D011014 lung inflammation
MESH:D012131 respiratory dendritic|respiratory failure
MESH:D012220 decreased rhinitis
MESH:D013927 Thrombosis|thrombosis
MESH:D015431 weight loss
MESH:D017563 interstitial disease
MESH:D018352 coronavirus infections|coronavirus infection
MESH:D045169 Severe acute respiratory syndrome
MESH:D055370 alveolar damage
MESH:D057772 Pulmonary Vascular Endothelialitis
MESH:D065631 allergic rhinitis
rs1053878 Affx-33346826
G/A
ABO 28 9:133256264 1
 33750629
DNA genotyping of the ABO gene showed a significant association of the A-group (A1/A2 variants) with severe COVID-19.
Gómez J, et. al. (2021); Eur J Intern Med; 2021 Feb 25 . doi:10.1016/j.ejim.2021.02.016
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|Covid-19|COVID-19
MESH:D001102 viral infection
MESH:D001778 coagulation
MESH:D002318 cardiovascular disease
MESH:D003643 mortality
MESH:D006973 Hypertension|hypertension|hypertensives
MESH:D007239 infected|infection
MESH:D011014 Pneumonia|pneumonia
MESH:D012120 acute respiratory syndrome|respiratory syndrome
MESH:D012131 Respiratory Failure|respiratory failure
MESH:D013923 thromboembolic and arterial disease
MESH:D014842 von Willebrand
MESH:D020246 deep-vein thrombosis|venous thrombotic
rs1057440362
C/T
SRL 6345 16:4242199 1
 33101356
Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene Variants.
Iyer GR, et. al. (2020); Front Genet; 2020 ; 11 861. doi:10.3389/fgene.2020.00861
MESH:C000657245 covid-19|SARS-CoV-2 infection|COVID19|novel coronavirus disease|COVID-19
MESH:C536174 panbronchiolitis
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001249 asthma
MESH:D001988 bronchiolitis
MESH:D002318 cardiovascular disorders
MESH:D003092 colitis
MESH:D003141 infectious diseases
MESH:D003229 conjunctival infection
MESH:D003586 cytomegalovirus disease
MESH:D003643 mortality
MESH:D003715 dengue fever
MESH:D003920 diabetes|diabetes mellitus
MESH:D004342 allergic
MESH:D004417 shortness of breath
MESH:D004675 tick-borne encephalitis
MESH:D005355 fibrosis
MESH:D006333 chronic heart failure
MESH:D006965 hyperplasia
MESH:D007239 establishing infections|infections|infection|infected
MESH:D007249 inflammation
MESH:D008171 lung abnormalities|lung disease|lung diseases
MESH:D009080 Kawasaki disease
MESH:D011009 pneumoconiosis
MESH:D011471 prostate cancer
MESH:D011658 pulmonary fibrosis
MESH:D012128 respiratory distress
MESH:D012131 respiratory disorders|respiratory failure
MESH:D012140 respiratory illness
MESH:D012141 upper respiratory infection
MESH:D014376 tuberculosis
MESH:D014397 pulmonary tuberculosis
MESH:D015179 colorectal cancer
MESH:D015658 HIV-1 infection
MESH:D018352 coronavirus disease|MERS|Middle East Respiratory Syndrome
MESH:D018980 Williams
MESH:D020521 stroke
MESH:D030342 genetic disease
MESH:D054243 vesicular stomatitis virus infection
MESH:D054990 idiopathic pulmonary fibrosis|Idiopathic pulmonary fibrosis
MESH:D055371 acute lung injury
MESH:D055744 invasive pulmonary aspergillosis infection|invasive pulmonary Aspergillosis infection
MESH:D058625 end-stage lung disease
MESH:D064420 memory Cytotoxic T
rs1057516488
C/T
C9orf3 84909 9:95107082 1
 33599292
Development and application of sensitive, specific and rapid CRISPR-Cas13-based diagnosis.
Gao D, et. al. (2021); J Med Virol; 2021 Feb 18 . doi:10.1002/jmv.26889
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|coronavirus disease-2019|COVID-19
MESH:D001102 viral infection
MESH:D001327 autoimmune diseases
MESH:D002908 chronic diseases|chronic disease
MESH:D003141 infectious disease|infectious diseases
MESH:D003643 A clear determination of infection
MESH:D003920 diabetes
MESH:D005199 Fanconi anemia
MESH:D007239 Infection|infections|infected|infection
MESH:D007674 embryonic kidney
MESH:D009369 cancer|tumor
MESH:D011125 APC|familial adenomatous polyposis
MESH:D015047 zoonotic
MESH:D018352 MERS
MESH:D018500 X-linked nephrogenic diabetes insipidus
rs1057518979
G/A
MUT 4594 6:49459429 1
 32645951
Implications of SARS-CoV-2 Mutations for Genomic RNA Structure and Host microRNA Targeting.
Hosseini Rad Sm A, et. al. (2020); Int J Mol Sci; 2020 Jul 07 ; 21 (13) . doi:10.3390/ijms21134807
MESH:C000657245 SARS-CoV-2 infection|COVID-19
MESH:C535807 MBS
MESH:C564479 silencer (ISS) motifs
MESH:D001102 Virus Infection|viral infection|virus infection|viral infections
MESH:D001943 breast tumor
MESH:D002318 cardiovascular disease|cardiovascular death|cardiovascular events
MESH:D003324 coronary artery disease
MESH:D003643 mortality
MESH:D005355 myocardial fibrosis
MESH:D006331 heart disease
MESH:D006332 cardiac hypertrophy
MESH:D006333 heart failure
MESH:D006479 Crimean-Congo hemorrhagic fever disease
MESH:D006509 HBV infection|hepatitis B virus-infected|hepatitis B
MESH:D006525 hepatitis viruses
MESH:D006528 hepatocellular carcinoma
MESH:D007153 CpG deficiency
MESH:D007239 infections|infected|infection
MESH:D008107 liver diseases
MESH:D009369 cancer|tumor|tumour
MESH:D012128 acute respiratory distress syndrome
MESH:D012640 fitness
MESH:D013274 gastric cancer|gastric cancers
MESH:D015047 zoonotic
MESH:D019142 Ebola virus infections
MESH:D045169 SARS infection
rs1058867
G/A
IL10RB 3588 21:33297076 1
 33246355
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.
Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
MESH:C000657245 coronavirus 2 infection|SARS-CoV-2 infection|coronavirus disease 2019|coronavirus (2019-nCoV) infections|COVID-19
MESH:D000077192 lung adenocarcinoma
MESH:D001281 atrial fibrillation
MESH:D001943 Breast cancer
MESH:D002318 cardiovascular diseases
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004487 oedema
MESH:D004646 emphysema
MESH:D005334 fever
MESH:D007239 infection|infected
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 lung damage
MESH:D008175 lung cancer
MESH:D009102 multiple organ failure|sepsis and organ failure
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012818 respiratory and gastrointestinal infections
MESH:D018352 coronavirus disease
MESH:D055370 lung injury|chronic lung disease
MESH:D055371 acute lung injury
MESH:D063806 muscle soreness
rs1059293
C/T
TMEM50B 757 21:33437386 1
 33246355
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.
Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
MESH:C000657245 coronavirus 2 infection|SARS-CoV-2 infection|coronavirus disease 2019|coronavirus (2019-nCoV) infections|COVID-19
MESH:D000077192 lung adenocarcinoma
MESH:D001281 atrial fibrillation
MESH:D001943 Breast cancer
MESH:D002318 cardiovascular diseases
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004487 oedema
MESH:D004646 emphysema
MESH:D005334 fever
MESH:D007239 infection|infected
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 lung damage
MESH:D008175 lung cancer
MESH:D009102 multiple organ failure|sepsis and organ failure
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012818 respiratory and gastrointestinal infections
MESH:D018352 coronavirus disease
MESH:D055370 lung injury|chronic lung disease
MESH:D055371 acute lung injury
MESH:D063806 muscle soreness
rs1059983
A/T
PPIA 5478 7:44799764 1
 26318518
Genetic deficiency and polymorphisms of cyclophilin A reveal its essential role for Human Coronavirus 229E replication.
von Brunn A, et. al. (2015); Curr Opin Virol; 2015 Oct; 1456-61. doi:10.1016/j.coviro.2015.08.004
- MERS-CoV infections
MESH:C000657245 CoV|SARS-CoV, HCoV-NL63|HCoV-NL63, HCoV-HKU1, SARS-CoV and MERS-CoV|coronaviruses SARS-CoV, HCoV-NL63|SARS-CoV and MERS-CoV viruses|SARS-CoV|CoV infection
MESH:C537931 pan-CoV
MESH:D001102 viral infection
MESH:D002371 Feline CoV (FCoV) serotypes I
MESH:D003324 coronary artery disease
MESH:D003333 SARS-CoV, HCoV-229E|CoV-229E|HCoV-229E-LUC virus-infected
MESH:D006526 HCV infection|hepatitis C virus infection
MESH:D006528 hepatocellular carcinoma
MESH:D007239 FCoV infection|infections|infection
MESH:D011014 pneumonia
MESH:D011488 CoV proteins
MESH:D012131 respiratory syndrome
MESH:D012141 respiratory tract infections|infection of respiratory and gastrointestinal
MESH:D014842 von Hahn|von
MESH:D015658 virus infection
MESH:D016766 Feline Infectious Peritonitis|CoV Feline Infectious Peritonitis Virus
MESH:D018352 middle east respiratory syndrome coronavirus infection|middle East respiratory syndrome|coronavirus HKU1|coronavirus|SARS-coronavirus-host|coronavirus infection|Ausbruch von MERS-Coronavirus|Respiratory Syndrome Coronavirus|SARS coronavirus tightly
MESH:D030342 genetic deficiency|Genetic deficiency
MESH:D045169 Coronaviruses post-SARS
rs1061147 Affx-6438960
A/C
CFH 3075 1:196685194 1
 33102952
Complement in secondary thrombotic microangiopathy.
Palma LMP, et. al. (2020); Kidney Int Rep; 2020 Oct 21 . doi:10.1016/j.ekir.2020.10.009
MESH:C000656865 P-aHUS
MESH:C000657245 SARS-CoV-2 infection|Covid-19|COVID-19
MESH:C537005 C5 blockade
MESH:C537147 Oklahoma
MESH:C537359 methylmalonic aciduria cblC
MESH:C537418 C (cblC) deficiency
MESH:C543759 Scleroderma|scleroderma
MESH:C565633 pulmonary vasculature
MESH:C567355 Complement-Mediated Disorders
MESH:D000081207 complement dysfunction
MESH:D000230 pancreatic adenocarcinoma
MESH:D000743 haemolytic uraemic syndrome|microangiopathic hemolytic anemia
MESH:D000783 TMA
MESH:D000848 H Ab aHUS
MESH:D001002 anuria
MESH:D001102 Viral infections|Virus Infection|viral infections
MESH:D001327 autoimmune disease|autoimmune diseases|Autoimmune Diseases
MESH:D001778 Altered Coagulation|coagulation disorders
MESH:D003141 infectious diseases
MESH:D003643 mortality
MESH:D003715 dengue infection
MESH:D004211 Disseminated Intravascular Coagulation
MESH:D004402 FD
MESH:D004461 eclampsia
MESH:D004487 swelling
MESH:D005334 fever|Fever
MESH:D005921 glomerulonephritis
MESH:D006417 hematuria
MESH:D006461 Hemolysis
MESH:D006463 hemolytic-uremic syndrome|hemolytic uremic syndrome|hemolytic uremic syndromes|Hemolytic Uremic Syndrome|HUS|STEC-HUS|H Ab STEC-HUS|HUS STEC-HUSStreptococcus|Hemolytic uremic syndrome
MESH:D006712 homocystinuria
MESH:D006973 hypertension-MOD|Hypertension|hypertension|Hypertensive Crisis|hypertensive|Hypertensive Emergency
MESH:D006974 Malignant Hypertension|Malignant hypertension|malignant hypertension
MESH:D007153 complement defects|Complement Defects|complement blockade|abnormalities of the complement|deficiency|Complement abnormalities|complement abnormalities
MESH:D007239 Infections|Infection|infections|infection
MESH:D007511 ischemia
MESH:D007674 IgA nephropathy|Scleroderma Renal Crisis|renal disease|renal injury|scleroderma renal crisis|Glomerular Diseases|Scleroderma renal crisis and renal involvement|glomerular diseases|thrombi in glomerular capillaries|glomerular capillaries|Differentiating scleroderma renal crisis|IgA Nephropathy|glomerular thrombi|C3 glomerulopathy|Scleroderma renal crisis|glomerular deposits|C3 Glomerulopathy|eculizumab in scleroderma renal crisis|renal diseases
MESH:D007676 end stage renal disease|End Stage Kidney Disease
MESH:D008180 lupus|systemic lupus erythematosus|Lupus Erythematosus (SLE), Antiphospholipid Syndrome|SLE
MESH:D008181 renal TMA in lupus nephritis|lupus nephritis
MESH:D008201 intestinal lymphangiectasia
MESH:D008288 malaria|Malaria
MESH:D009102 organ dysfunction
MESH:D009336 necrosis
MESH:D009369 malignancy|cancer
MESH:D010265 Monoclonal gammopathy|gammopathy
MESH:D010300 PD
MESH:D011125 coli-HUS
MESH:D011693 purpura
MESH:D011697 Thrombotic thrombocytopenic purpura|Thrombotic Thrombocytopenic Purpura|thrombotic thrombocytopenic purpura|congenital thrombotic thrombocytopenic purpura
MESH:D012080 HUS Eculizumab/CKD Aldridge
MESH:D012141 Respiratory tract infection
MESH:D012595 systemic sclerosis
MESH:D013921 Thrombocytopenia|thrombocytopenia
MESH:D013927 intravascular thrombosis|Thrombotic Angiopathies and Antiphospholipid Syndrome|thrombotic
MESH:D014917 Bordetella pertussis infection
MESH:D014947 injury|endothelial injury
MESH:D015882 acute cortical necrosis
MESH:D016736 Antiphospholipid Syndrome|refractory catastrophic antiphospholipid syndrome|Coagulopathy and Antiphospholipid Antibodies|Catastrophic antiphospholipid syndrome|Anti-phospholipid syndrome|catastrophic antiphospholipid syndrome|antiphospholipid syndrome
MESH:D016780 vivax malaria
MESH:D016873 Ehrlichiosis infection
MESH:D016884 APS
MESH:D017359 eclampsia and HELLP syndrome|preeclampsia and HELLP syndrome
MESH:D017695 tissue injury
MESH:D018805 sepsis
MESH:D019851 hypercoagulability
MESH:D020022 genetic complement alterations
MESH:D020936 familial aHUS
MESH:D030342 Genetic abnormalities|genetic defects|genetic abnormalities|genetic complement abnormalities
MESH:D034721 systemic diseases
MESH:D045169 Severe deficiency
MESH:D051437 Microangiopathic hemolysis and renal failure|Renal Failure
MESH:D055370 lung injury
MESH:D057049 Thrombotic microangiopathy|thrombotic microangiopathies|Renal Thrombotic Microangiopathy|Thrombotic Microangiopathy|renal thrombotic microangiopathy|Thrombotic Microangiopathy and IgA Nephropathy|Thrombotic microangiopathies|thrombotic microangiopathy syndrome|Thrombotic Microangiopathies|thrombotic microangiopathy
MESH:D058186 acute renal failure|acute kidney injury|kidney injury|Acute kidney injury
MESH:D064420 toxicity
MESH:D065766 Atypical hemolytic uremic syndrome|Atypical Hemolytic Uremic Syndrome|Atypical Uremic Hemolytic Syndrome
rs1061170
C/T
CFH 3075 1:196690107 3
 32637948
Genetic architecture of host proteins interacting with SARS-CoV-2.
Pietzner M, et. al. (2020); bioRxiv; 2020 Jul 01 . doi:10.1101/2020.07.01.182709
MESH:C000657245 CoV-2 infection|SARS-Cov-2 infection|covid-19|SARS-CoV-2 infection|coronavirus disease 2019|Covid-19|COVID-19
MESH:D000783 arterial vascular disease
MESH:D000795 Fabry's disease
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma|asthma-GRS
MESH:D001778 coagulopathy
MESH:D002318 Cardiovascular Disease
MESH:D003139 Common Complex Disease
MESH:D003324 coronary artery disease|coronary heart disease|Coronary Disease
MESH:D003643 mortality|Mortality
MESH:D003920 diabetes mellitus|diabetes
MESH:D003924 Type 2 Diabetes|type 2 diabetes
MESH:D004342 allergic disease
MESH:D007239 infected
MESH:D007249 inflammation
MESH:D007319 inability
MESH:D009336 necrotic
MESH:D009800 deterioration
MESH:D010300 Parkinson's disease
MESH:D011618 psychotic disorder
MESH:D011655 pulmonary embolism
MESH:D012131 respiratory failure
MESH:D013924 phlebitis and thrombophlebitis
MESH:D014842 van Willebrand
MESH:D018352 Coronavirus disease
MESH:D019851 hypercoagulation
MESH:D020246 venous thrombosis
MESH:D029424 chronic obstructive pulmonary disease
MESH:D054556 venous thromboembolism
 33102952
Complement in secondary thrombotic microangiopathy.
Palma LMP, et. al. (2020); Kidney Int Rep; 2020 Oct 21 . doi:10.1016/j.ekir.2020.10.009
MESH:C000656865 P-aHUS
MESH:C000657245 SARS-CoV-2 infection|Covid-19|COVID-19
MESH:C537005 C5 blockade
MESH:C537147 Oklahoma
MESH:C537359 methylmalonic aciduria cblC
MESH:C537418 C (cblC) deficiency
MESH:C543759 Scleroderma|scleroderma
MESH:C565633 pulmonary vasculature
MESH:C567355 Complement-Mediated Disorders
MESH:D000081207 complement dysfunction
MESH:D000230 pancreatic adenocarcinoma
MESH:D000743 haemolytic uraemic syndrome|microangiopathic hemolytic anemia
MESH:D000783 TMA
MESH:D000848 H Ab aHUS
MESH:D001002 anuria
MESH:D001102 Viral infections|Virus Infection|viral infections
MESH:D001327 autoimmune disease|autoimmune diseases|Autoimmune Diseases
MESH:D001778 Altered Coagulation|coagulation disorders
MESH:D003141 infectious diseases
MESH:D003643 mortality
MESH:D003715 dengue infection
MESH:D004211 Disseminated Intravascular Coagulation
MESH:D004402 FD
MESH:D004461 eclampsia
MESH:D004487 swelling
MESH:D005334 fever|Fever
MESH:D005921 glomerulonephritis
MESH:D006417 hematuria
MESH:D006461 Hemolysis
MESH:D006463 hemolytic-uremic syndrome|hemolytic uremic syndrome|hemolytic uremic syndromes|Hemolytic Uremic Syndrome|HUS|STEC-HUS|H Ab STEC-HUS|HUS STEC-HUSStreptococcus|Hemolytic uremic syndrome
MESH:D006712 homocystinuria
MESH:D006973 hypertension-MOD|Hypertension|hypertension|Hypertensive Crisis|hypertensive|Hypertensive Emergency
MESH:D006974 Malignant Hypertension|Malignant hypertension|malignant hypertension
MESH:D007153 complement defects|Complement Defects|complement blockade|abnormalities of the complement|deficiency|Complement abnormalities|complement abnormalities
MESH:D007239 Infections|Infection|infections|infection
MESH:D007511 ischemia
MESH:D007674 IgA nephropathy|Scleroderma Renal Crisis|renal disease|renal injury|scleroderma renal crisis|Glomerular Diseases|Scleroderma renal crisis and renal involvement|glomerular diseases|thrombi in glomerular capillaries|glomerular capillaries|Differentiating scleroderma renal crisis|IgA Nephropathy|glomerular thrombi|C3 glomerulopathy|Scleroderma renal crisis|glomerular deposits|C3 Glomerulopathy|eculizumab in scleroderma renal crisis|renal diseases
MESH:D007676 end stage renal disease|End Stage Kidney Disease
MESH:D008180 lupus|systemic lupus erythematosus|Lupus Erythematosus (SLE), Antiphospholipid Syndrome|SLE
MESH:D008181 renal TMA in lupus nephritis|lupus nephritis
MESH:D008201 intestinal lymphangiectasia
MESH:D008288 malaria|Malaria
MESH:D009102 organ dysfunction
MESH:D009336 necrosis
MESH:D009369 malignancy|cancer
MESH:D010265 Monoclonal gammopathy|gammopathy
MESH:D010300 PD
MESH:D011125 coli-HUS
MESH:D011693 purpura
MESH:D011697 Thrombotic thrombocytopenic purpura|Thrombotic Thrombocytopenic Purpura|thrombotic thrombocytopenic purpura|congenital thrombotic thrombocytopenic purpura
MESH:D012080 HUS Eculizumab/CKD Aldridge
MESH:D012141 Respiratory tract infection
MESH:D012595 systemic sclerosis
MESH:D013921 Thrombocytopenia|thrombocytopenia
MESH:D013927 intravascular thrombosis|Thrombotic Angiopathies and Antiphospholipid Syndrome|thrombotic
MESH:D014917 Bordetella pertussis infection
MESH:D014947 injury|endothelial injury
MESH:D015882 acute cortical necrosis
MESH:D016736 Antiphospholipid Syndrome|refractory catastrophic antiphospholipid syndrome|Coagulopathy and Antiphospholipid Antibodies|Catastrophic antiphospholipid syndrome|Anti-phospholipid syndrome|catastrophic antiphospholipid syndrome|antiphospholipid syndrome
MESH:D016780 vivax malaria
MESH:D016873 Ehrlichiosis infection
MESH:D016884 APS
MESH:D017359 eclampsia and HELLP syndrome|preeclampsia and HELLP syndrome
MESH:D017695 tissue injury
MESH:D018805 sepsis
MESH:D019851 hypercoagulability
MESH:D020022 genetic complement alterations
MESH:D020936 familial aHUS
MESH:D030342 Genetic abnormalities|genetic defects|genetic abnormalities|genetic complement abnormalities
MESH:D034721 systemic diseases
MESH:D045169 Severe deficiency
MESH:D051437 Microangiopathic hemolysis and renal failure|Renal Failure
MESH:D055370 lung injury
MESH:D057049 Thrombotic microangiopathy|thrombotic microangiopathies|Renal Thrombotic Microangiopathy|Thrombotic Microangiopathy|renal thrombotic microangiopathy|Thrombotic Microangiopathy and IgA Nephropathy|Thrombotic microangiopathies|thrombotic microangiopathy syndrome|Thrombotic Microangiopathies|thrombotic microangiopathy
MESH:D058186 acute renal failure|acute kidney injury|kidney injury|Acute kidney injury
MESH:D064420 toxicity
MESH:D065766 Atypical hemolytic uremic syndrome|Atypical Hemolytic Uremic Syndrome|Atypical Uremic Hemolytic Syndrome
 33328453
Genetic architecture of host proteins involved in SARS-CoV-2 infection.
Pietzner M, et. al. (2020); Nat Commun; 2020 12 16 ; 11 (1) 6397. doi:10.1038/s41467-020-19996-z
MESH:C000657245 CoV-2 infection|covid-19|SARS-CoV-2 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|Covid-19|COVID-19
MESH:D000783 arterial vascular disease
MESH:D000795 Fabry's disease
MESH:D001172 rheumatoid arthritis|RA
MESH:D001249 asthma|asthma-GRS
MESH:D001778 coagulopathy
MESH:D002318 cardiovascular traits|Cardiovascular disease|cardiovascular disease
MESH:D003324 coronary artery disease|coronary disease|coronary heart disease
MESH:D003643 mortality|death
MESH:D003920 diabetes|diabetes mellitus
MESH:D004342 allergic disease
MESH:D007105 complex disease
MESH:D007239 Infection|infected|infection
MESH:D007249 inflammation
MESH:D007319 inability
MESH:D009336 necrotic
MESH:D009800 deterioration
MESH:D010300 Parkinson's disease
MESH:D011618 psychotic disorder
MESH:D011655 pulmonary embolism
MESH:D012131 respiratory failure
MESH:D013924 phlebitis and thrombophlebitis
MESH:D014842 van Willebrand
MESH:D016638 critical illness
MESH:D018352 Coronavirus disease
MESH:D019851 hypercoagulation|Hypercoagulation
MESH:D020246 venous thrombosis
MESH:D029424 chronic obstructive pulmonary disease
MESH:D054556 venous thromboembolism
rs1061622 Affx-4748563
T/G
TNFRSF1B 7133 1:12192898 2
 33246355
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.
Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
MESH:C000657245 coronavirus 2 infection|SARS-CoV-2 infection|coronavirus disease 2019|coronavirus (2019-nCoV) infections|COVID-19
MESH:D000077192 lung adenocarcinoma
MESH:D001281 atrial fibrillation
MESH:D001943 Breast cancer
MESH:D002318 cardiovascular diseases
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004487 oedema
MESH:D004646 emphysema
MESH:D005334 fever
MESH:D007239 infection|infected
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 lung damage
MESH:D008175 lung cancer
MESH:D009102 multiple organ failure|sepsis and organ failure
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012818 respiratory and gastrointestinal infections
MESH:D018352 coronavirus disease
MESH:D055370 lung injury|chronic lung disease
MESH:D055371 acute lung injury
MESH:D063806 muscle soreness
 33342718
Macrophage-derived cytokines in pneumonia: Linking cellular immunology and genetics.
Dukhinova M, et. al. (2020); Cytokine Growth Factor Rev; 2020 Dec 03 . doi:10.1016/j.cytogfr.2020.11.003
MESH:C000657245 COVID-19 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|COVID19|COVID19 disease|novel coronavirus pneumonia|SARS-CoV-Infected|SARS-CoV-2-Infected|SARS-CoV-2-infected|Covid-19|COVID-19|new coronavirus disease
MESH:C537409 Stat-1 deficiency
MESH:C563662 Invasive pneumococcal disease|invasive pneumococcal disease
MESH:C565292 atopic asthma
MESH:C567070 deficiency mycobacterial disease
MESH:D000081207 Primary Immunodeficiencies
MESH:D000755 sickle cell disease
MESH:D001102 Virus Infection|virus infection|viral infection|viral infections
MESH:D001170 septic complications
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma|adult asthma
MESH:D001327 autoimmunity|autoimmune disease|autoimmune diseases
MESH:D001424 bacterial infection
MESH:D001766 complete IRF9 deficiency
MESH:D001943 breast Cancer|breast cancer|Breast cancer
MESH:D002318 cardiovascular disorders|cardiovascular and metabolic disorders|cardiovascular damage
MESH:D003141 Monogenic Diseases|infectious diseases|Infectious disease
MESH:D003550 cystic fibrosis
MESH:D003643 mortality
MESH:D003920 diabetes|diabetes mellitus|diabetic|Diabetes
MESH:D003924 type 2 diabetes mellitus
MESH:D003928 Diabetic nephropathy|diabetic nephropathy
MESH:D005355 fibrosis|lung fibrosis
MESH:D005910 asthma in glioma
MESH:D006509 hepatitis B, hepatitis C
MESH:D006937 hypercholesterolemia
MESH:D006976 pulmonary hypertension
MESH:D007153 PPARgamma deficiency|deficiency|immunodeficiency
MESH:D007154 immune disorders
MESH:D007239 Infection|Infections|Tuberculosis infection|infections|infection|infected
MESH:D007249 allergic airway inflammation|inflammation|Inflammation
MESH:D008171 lung dysfunction|lung disease|lung damage|lung immunoparalysis
MESH:D008175 lung cancer|lung Cancer|Lung tumors
MESH:D008180 systemic lupus erythematosus|SLE
MESH:D008545 melanoma
MESH:D008581 Meningitis
MESH:D008586 pneumococcal meningitis
MESH:D008659 metabolic disorders
MESH:D008661 Inborn errors
MESH:D009102 multiorganic failure|systemic organ failure
MESH:D009202 cardiomyopathy|Inflammatory cardiomyopathy
MESH:D009336 tumor necrosis
MESH:D009369 Cancer|cancer|tumor
MESH:D009461 dysfunctional
MESH:D010051 ovarian cancer
MESH:D010149 postoperative pneumonia|Postoperative pneumonia
MESH:D011008 pneumococcal pneumonia
MESH:D011014 pneumonias|comorbidity-pneumonia|pneumonia|pneumonitis|Pneumonia|Lung inflammation|pulmonary inflammation|pulmonary inflammatory diseases|lung inflammation
MESH:D011020 Pneumocystis pneumonia|Pneumocystis jirovecii pneumonia
MESH:D011471 prostate cancer aggressiveness|prostate cancer
MESH:D011649 alveolar proteinosis|pulmonary alveolar proteinosis
MESH:D011655 pulmonary obstruction
MESH:D011658 pulmonary fibrosis
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 respiratory distress syndrome|acute respiratory distress syndrome
MESH:D012131 respiratory failure|lung fibrosis and organ failure
MESH:D012140 respiratory disease
MESH:D012141 lung infections|Respiratory infection|Lung infection
MESH:D012595 systemic sclerosis
MESH:D012772 septic shock
MESH:D012857 pulmonary tissue damage in SIV-infected
MESH:D014095 impacts disease
MESH:D014947 trauma
MESH:D015212 inflammatory bowel disease
MESH:D015472 acute eosinophilic pneumonia
MESH:D015499 functional deficiency
MESH:D016920 bacterial pneumonia|bacterial pneumonias
MESH:D018357 Respiratory Syncytial Virus Infected|respiratory syncytial virus infection
MESH:D018805 Sepsis|sepsis
MESH:D020814 Escherichia coli pneumonia
MESH:D024821 metabolic syndrome
MESH:D029424 Chronic obstructive lung disorder|chronic obstructive pulmonary disease|COPD|asthma and chronic obstructive airways disease
MESH:D030342 inborn|inherited IRF9 deficiency
MESH:D034721 Systemic disorders
MESH:D045169 severe disease
MESH:D054243 oncolytic vesicular stomatitis|Oncolytic vesicular stomatitis
MESH:D055370 lung injury|pulmonary injury
MESH:D056586 acute chest syndrome|chest syndrome
rs1061624
A/G
TNFRSF1B 7133 1:12207208 2
 33246355
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.
Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
MESH:C000657245 coronavirus 2 infection|SARS-CoV-2 infection|coronavirus disease 2019|coronavirus (2019-nCoV) infections|COVID-19
MESH:D000077192 lung adenocarcinoma
MESH:D001281 atrial fibrillation
MESH:D001943 Breast cancer
MESH:D002318 cardiovascular diseases
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004487 oedema
MESH:D004646 emphysema
MESH:D005334 fever
MESH:D007239 infection|infected
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 lung damage
MESH:D008175 lung cancer
MESH:D009102 multiple organ failure|sepsis and organ failure
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012818 respiratory and gastrointestinal infections
MESH:D018352 coronavirus disease
MESH:D055370 lung injury|chronic lung disease
MESH:D055371 acute lung injury
MESH:D063806 muscle soreness
 33901540
Will a little change do you good? A putative role of polymorphisms in COVID-19.
Paim AAO, et. al. (2021); Immunol Lett; 2021 Apr 23 . doi:10.1016/j.imlet.2021.04.005
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-2 infections|SARS-CoV-2 Infections|SARS-CoV Infection|SARS-CoV-1 infection|SARS-Cov infection|Coronavirus Disease 2019|SARS-CoV-2-infected|SARS-CoV-2 Infection|Covid-19|coronavirus disease-2019|COVID-19
MESH:D000860 hypoxia
MESH:D001102 viral-infected|viral infections
MESH:D002318 cardiovascular disease
MESH:D003141 infectious disorders|infectious diseases
MESH:D003371 cough
MESH:D003643 Mortality|mortality|deaths|death
MESH:D003920 diabetes
MESH:D003967 diarrhea
MESH:D004342 allergies
MESH:D004417 shortness of breath
MESH:D005221 fatigue
MESH:D005271 femoral head necrosis
MESH:D005334 fever
MESH:D006261 headaches
MESH:D006331 cardiac injury
MESH:D006527 Wilson
MESH:D007154 dysfunctional immunity
MESH:D007239 infections|infected|infection
MESH:D007249 hyper inflammation|inflammation
MESH:D009102 organ failure
MESH:D011014 pneumonia
MESH:D012128 respiratory distress syndrome|acute respiratory distress syndrome|ARDS
MESH:D012141 respiratory infections
MESH:D014376 tuberculosis
MESH:D015658 HIV
MESH:D016638 critically ill|septic pediatric critically ill
MESH:D018352 respiratory syndrome coronavirus infection|coronavirus infection|Coronavirus disease|CoV infection
MESH:D018357 respiratory syncytial virus infection
MESH:D018805 sepsis
MESH:D045169 SARS|severe acute respiratory syndrome|Severe Acute Respiratory Syndrome
MESH:D063806 myalgia
rs1061628 Affx-4751227
C/T
TNFRSF1B 7133 1:12207942 1
 33246355
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.
Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
MESH:C000657245 coronavirus 2 infection|SARS-CoV-2 infection|coronavirus disease 2019|coronavirus (2019-nCoV) infections|COVID-19
MESH:D000077192 lung adenocarcinoma
MESH:D001281 atrial fibrillation
MESH:D001943 Breast cancer
MESH:D002318 cardiovascular diseases
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004487 oedema
MESH:D004646 emphysema
MESH:D005334 fever
MESH:D007239 infection|infected
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 lung damage
MESH:D008175 lung cancer
MESH:D009102 multiple organ failure|sepsis and organ failure
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012818 respiratory and gastrointestinal infections
MESH:D018352 coronavirus disease
MESH:D055370 lung injury|chronic lung disease
MESH:D055371 acute lung injury
MESH:D063806 muscle soreness
rs1063340
G/C,T
CCL3 6348 17:36088417 1
 33246355
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.
Karakas Celik S, et. al. (2020); Int J Immunogenet; 2020 Nov 27 . doi:10.1111/iji.12522
MESH:C000657245 coronavirus 2 infection|SARS-CoV-2 infection|coronavirus disease 2019|coronavirus (2019-nCoV) infections|COVID-19
MESH:D000077192 lung adenocarcinoma
MESH:D001281 atrial fibrillation
MESH:D001943 Breast cancer
MESH:D002318 cardiovascular diseases
MESH:D002561 vascular dysfunction
MESH:D003141 infectious diseases
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes
MESH:D004487 oedema
MESH:D004646 emphysema
MESH:D005334 fever
MESH:D007239 infection|infected
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 lung damage
MESH:D008175 lung cancer
MESH:D009102 multiple organ failure|sepsis and organ failure
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012818 respiratory and gastrointestinal infections
MESH:D018352 coronavirus disease
MESH:D055370 lung injury|chronic lung disease
MESH:D055371 acute lung injury
MESH:D063806 muscle soreness
rs1064651
C/G
GBA 2629 1:155235727 1
 32471800
Gaucher disease and SARS-CoV-2 infection: Emerging management challenges.
Mistry P, et. al. (2020); Mol Genet Metab; 2020 07 ; 130 (3) 164-169. doi:10.1016/j.ymgme.2020.05.002
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|COVID-19 illness|COVID19|SARS-CoV-2 infections|novel coronavirus pneumonia|SAR-CoV-2 infection|SARS-CoV-2 infected|CoV-2 infection|SARS-CoV-2 disease|CoV-2 infected|Covid-19|COVID-19|coronavirus disease 2019 pneumonia
MESH:C535727 hepatosplenomegaly
MESH:C538137 hyperferritinemia
MESH:D000783 pulmonary vascular disease
MESH:D000860 hypoxemia|hypoxia
MESH:D001102 viral disease
MESH:D001424 bacterial infection
MESH:D001778 coagulopathy
MESH:D001847 cytopenia and bone disease
MESH:D002114 valvular calcification, aortic calcification
MESH:D002318 cardiovascular calcifications
MESH:D002908 chronic disorders
MESH:D003141 infectious disease
MESH:D003324 non-atherosclerotic coronary artery disease
MESH:D003371 cough
MESH:D003643 mortality|death
MESH:D003920 diabetes mellitus|diabetes
MESH:D004406 dysgammaglobulinemia
MESH:D004417 dyspnea
MESH:D005124 eye movement abnormalities
MESH:D005221 fatigue|malaise
MESH:D005334 fevers|fever
MESH:D005767 gastrointestinal disturbance
MESH:D005776 glucocerebrosidase|Gaucher disease type 1|Gaucher macrophages|Gaucher type I|GD infected|Type 1 Gaucher disease|Gaucher type I disease|glucocerebrosidase function|Gaucher disease|type I Gaucher|Gaucher's disease|GD type III|GD|gaucher disease
MESH:D006331 heart disease
MESH:D006349 calcification of heart valves
MESH:D006971 hypersplenism
MESH:D006973 hypertension|hypertensive
MESH:D006976 pulmonary hypertension
MESH:D007153 complement|immunodeficiency
MESH:D007154 immunological abnormalities
MESH:D007239 infections|infection|infected
MESH:D007244 infectious mononucleosis
MESH:D007249 metabolic inflammation|inflammation|chronic metabolic inflammation|Inflammation
MESH:D007674 kidney disease
MESH:D008171 pulmonary disease|lung disease|pulmonary syndrome
MESH:D008661 inborn errors of metabolism|inborn error of metabolism
MESH:D009080 Kawasaki Disease and Toxic Shock Syndrome
MESH:D009101 myeloma|gammopathy/myeloma|multiple myeloma
MESH:D009102 multiple organ dysfunction|multiorgan failure
MESH:D009205 myocarditis|hepatic impairment and myocarditis
MESH:D009369 malignancy|malignancies
MESH:D009404 nephrotic syndrome
MESH:D009765 obesity
MESH:D010243 palsy
MESH:D010300 Parkinson's disease
MESH:D010302 parkinsonism
MESH:D011014 pneumonia
MESH:D011649 pulmonary alveolar
MESH:D012120 acute respiratory disease syndrome
MESH:D012128 ARDS|acute respiratory distress syndrome
MESH:D012141 pulmonary infection
MESH:D013122 spinal deformities
MESH:D013163 splenomegaly
MESH:D013923 thromboembolic
MESH:D016464 lysosomal dysfunction|inborn lysosomal dysfunction
MESH:D017563 parenchymal lung disease
MESH:D018352 coronavirus infections|Coronavirus infections
MESH:D019337 hematological malignancies
MESH:D019636 neurodegenerative disorder
MESH:D020065 hepatopulmonary syndrome
MESH:D034721 multi-system inflammatory syndrome disease
MESH:D051359 hemophagocytic lymphohistiocytosis
MESH:D055370 lung injury|immunodeficiency,chronic lung disease|immunodeficiency and chronic lung disease
MESH:D059413 massive intra-abdominal lymphadenopathy
rs1064797077
G/A
AVPR2 554 X:153906384 1
 33599292
Development and application of sensitive, specific and rapid CRISPR-Cas13-based diagnosis.
Gao D, et. al. (2021); J Med Virol; 2021 Feb 18 . doi:10.1002/jmv.26889
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|coronavirus disease-2019|COVID-19
MESH:D001102 viral infection
MESH:D001327 autoimmune diseases
MESH:D002908 chronic diseases|chronic disease
MESH:D003141 infectious disease|infectious diseases
MESH:D003643 A clear determination of infection
MESH:D003920 diabetes
MESH:D005199 Fanconi anemia
MESH:D007239 Infection|infections|infected|infection
MESH:D007674 embryonic kidney
MESH:D009369 cancer|tumor
MESH:D011125 APC|familial adenomatous polyposis
MESH:D015047 zoonotic
MESH:D018352 MERS
MESH:D018500 X-linked nephrogenic diabetes insipidus
rs1065489
G/T
CFH 3075 1:196740644 1
 33102952
Complement in secondary thrombotic microangiopathy.
Palma LMP, et. al. (2020); Kidney Int Rep; 2020 Oct 21 . doi:10.1016/j.ekir.2020.10.009
MESH:C000656865 P-aHUS
MESH:C000657245 SARS-CoV-2 infection|Covid-19|COVID-19
MESH:C537005 C5 blockade
MESH:C537147 Oklahoma
MESH:C537359 methylmalonic aciduria cblC
MESH:C537418 C (cblC) deficiency
MESH:C543759 Scleroderma|scleroderma
MESH:C565633 pulmonary vasculature
MESH:C567355 Complement-Mediated Disorders
MESH:D000081207 complement dysfunction
MESH:D000230 pancreatic adenocarcinoma
MESH:D000743 haemolytic uraemic syndrome|microangiopathic hemolytic anemia
MESH:D000783 TMA
MESH:D000848 H Ab aHUS
MESH:D001002 anuria
MESH:D001102 Viral infections|Virus Infection|viral infections
MESH:D001327 autoimmune disease|autoimmune diseases|Autoimmune Diseases
MESH:D001778 Altered Coagulation|coagulation disorders
MESH:D003141 infectious diseases
MESH:D003643 mortality
MESH:D003715 dengue infection
MESH:D004211 Disseminated Intravascular Coagulation
MESH:D004402 FD
MESH:D004461 eclampsia
MESH:D004487 swelling
MESH:D005334 fever|Fever
MESH:D005921 glomerulonephritis
MESH:D006417 hematuria
MESH:D006461 Hemolysis
MESH:D006463 hemolytic-uremic syndrome|hemolytic uremic syndrome|hemolytic uremic syndromes|Hemolytic Uremic Syndrome|HUS|STEC-HUS|H Ab STEC-HUS|HUS STEC-HUSStreptococcus|Hemolytic uremic syndrome
MESH:D006712 homocystinuria
MESH:D006973 hypertension-MOD|Hypertension|hypertension|Hypertensive Crisis|hypertensive|Hypertensive Emergency
MESH:D006974 Malignant Hypertension|Malignant hypertension|malignant hypertension
MESH:D007153 complement defects|Complement Defects|complement blockade|abnormalities of the complement|deficiency|Complement abnormalities|complement abnormalities
MESH:D007239 Infections|Infection|infections|infection
MESH:D007511 ischemia
MESH:D007674 IgA nephropathy|Scleroderma Renal Crisis|renal disease|renal injury|scleroderma renal crisis|Glomerular Diseases|Scleroderma renal crisis and renal involvement|glomerular diseases|thrombi in glomerular capillaries|glomerular capillaries|Differentiating scleroderma renal crisis|IgA Nephropathy|glomerular thrombi|C3 glomerulopathy|Scleroderma renal crisis|glomerular deposits|C3 Glomerulopathy|eculizumab in scleroderma renal crisis|renal diseases
MESH:D007676 end stage renal disease|End Stage Kidney Disease
MESH:D008180 lupus|systemic lupus erythematosus|Lupus Erythematosus (SLE), Antiphospholipid Syndrome|SLE
MESH:D008181 renal TMA in lupus nephritis|lupus nephritis
MESH:D008201 intestinal lymphangiectasia
MESH:D008288 malaria|Malaria
MESH:D009102 organ dysfunction
MESH:D009336 necrosis
MESH:D009369 malignancy|cancer
MESH:D010265 Monoclonal gammopathy|gammopathy
MESH:D010300 PD
MESH:D011125 coli-HUS
MESH:D011693 purpura
MESH:D011697 Thrombotic thrombocytopenic purpura|Thrombotic Thrombocytopenic Purpura|thrombotic thrombocytopenic purpura|congenital thrombotic thrombocytopenic purpura
MESH:D012080 HUS Eculizumab/CKD Aldridge
MESH:D012141 Respiratory tract infection
MESH:D012595 systemic sclerosis
MESH:D013921 Thrombocytopenia|thrombocytopenia
MESH:D013927 intravascular thrombosis|Thrombotic Angiopathies and Antiphospholipid Syndrome|thrombotic
MESH:D014917 Bordetella pertussis infection
MESH:D014947 injury|endothelial injury
MESH:D015882 acute cortical necrosis
MESH:D016736 Antiphospholipid Syndrome|refractory catastrophic antiphospholipid syndrome|Coagulopathy and Antiphospholipid Antibodies|Catastrophic antiphospholipid syndrome|Anti-phospholipid syndrome|catastrophic antiphospholipid syndrome|antiphospholipid syndrome
MESH:D016780 vivax malaria
MESH:D016873 Ehrlichiosis infection
MESH:D016884 APS
MESH:D017359 eclampsia and HELLP syndrome|preeclampsia and HELLP syndrome
MESH:D017695 tissue injury
MESH:D018805 sepsis
MESH:D019851 hypercoagulability
MESH:D020022 genetic complement alterations
MESH:D020936 familial aHUS
MESH:D030342 Genetic abnormalities|genetic defects|genetic abnormalities|genetic complement abnormalities
MESH:D034721 systemic diseases
MESH:D045169 Severe deficiency
MESH:D051437 Microangiopathic hemolysis and renal failure|Renal Failure
MESH:D055370 lung injury
MESH:D057049 Thrombotic microangiopathy|thrombotic microangiopathies|Renal Thrombotic Microangiopathy|Thrombotic Microangiopathy|renal thrombotic microangiopathy|Thrombotic Microangiopathy and IgA Nephropathy|Thrombotic microangiopathies|thrombotic microangiopathy syndrome|Thrombotic Microangiopathies|thrombotic microangiopathy
MESH:D058186 acute renal failure|acute kidney injury|kidney injury|Acute kidney injury
MESH:D064420 toxicity
MESH:D065766 Atypical hemolytic uremic syndrome|Atypical Hemolytic Uremic Syndrome|Atypical Uremic Hemolytic Syndrome
rs1065852 Affx-19669904
G/A
LOC102723722 102723722 22:42130692 1
 32763298
Molecular effects and retinopathy induced by hydroxychloroquine during SARS-CoV-2 therapy: Role of CYP450 isoforms and epigenetic modulations.
Paniri A, et. al. (2020); Eur J Pharmacol; 2020 Nov 05 ; 886 173454. doi:10.1016/j.ejphar.2020.173454
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|Covid-19|COVID-19
MESH:C538365 autosomal recessive retinitis pigmentosa
MESH:D000080362 Stargardt disease
MESH:D000163 acquired immune deficiency syndrome
MESH:D000402 obstruction
MESH:D000787 angina
MESH:D001007 anxiety
MESH:D001102 viral infections
MESH:D001172 rheumatoid arthritis|RA
MESH:D001327 autoimmune disease|autoimmune diseases|autoimmune disorders
MESH:D001928 cerebral drug metabolism via brain miRNAs
MESH:D001943 breast tumor|Breast tumor|breast cancer
MESH:D002493 central nervous system disorders
MESH:D002637 chest pain
MESH:D002833 choroid capillaries
MESH:D003103 retina-choroid
MESH:D003141 infectious diseases
MESH:D003398 CRS
MESH:D003643 mortality|deaths|died
MESH:D003882 dermatomyositis
MESH:D004244 dizziness
MESH:D004408 dysgeusia
MESH:D004415 dyspepsia
MESH:D005076 rash
MESH:D005128 ocular toxicity
MESH:D005767 gastrointestinal difficulties
MESH:D005901 glaucoma eyes
MESH:D006261 headaches
MESH:D006528 hepatoma
MESH:D007239 infected|infection
MESH:D007249 inflammation|autoimmune inflammation
MESH:D007674 renal dysfunction|embryonic kidney
MESH:D007775 lactation
MESH:D008133 prolongation of the QT interval
MESH:D008178 cutaneous lupus erythematosus
MESH:D008180 systemic lupus erythematosus|SLE
MESH:D008288 malaria|malaria to autoimmunity
MESH:D008659 hepatocytic cholesterol metabolism
MESH:D009202 biventricular cardiomyopathy
MESH:D009369 cancerous|cancer|tumor|cancers|hematological cancer
MESH:D009765 obesity
MESH:D011125 APC
MESH:D011605 psychosis
MESH:D012164 retinal disease|Retinopathy|retinal damage|retinopathy|retinal toxicity
MESH:D012173 retinal pigmented
MESH:D012216 rheumatic diseases
MESH:D012640 convulsions
MESH:D012817 gastrointestinal problems
MESH:D012871 skin disorders
MESH:D014786 impaired vision
MESH:D015179 colorectal cancer
MESH:D015658 HIV-infection|HIV
MESH:D015799 OAT
MESH:D016464 lysosomal dysfunction
MESH:D016638 critically ill
MESH:D017093 liver injury promotion|liver injury
MESH:D017495 hyperpigmentation|skin hyperpigmentation
MESH:D018352 SARS coronavirus infection|coronavirus tropism
MESH:D019572 dystrophic retina
MESH:D019636 neurodegenerative diseases
MESH:D021081 rhythm disorders
MESH:D058499 retinal dystrophic RCS
MESH:D063646 carcinogenesis
MESH:D064420 toxicity|adverse neuropsychiatric reaction
MESH:D066126 cardiotoxicity
rs10735079
G/A
OAS3 4940 12:112942203 6
 33363283
Life-Threatening COVID-19: Defective Interferons Unleash Excessive Inflammation.
Zhang Q, et. al. (2020); Med (N Y); 2020 Dec 18 ; 1 (1) 14-20. doi:10.1016/j.medj.2020.12.001
MESH:C000657245 SARS-CoV-2 pneumonia|covid-19|COVID-19 pneumonia|Severe Coronavirus Pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|COVID-19 Pneumonia|SARS-CoV-2-infected|SARS-CoV-2 Infection|Covid-19|COVID-19|COVID
MESH:C537017 KD
MESH:D000544 AD deficiencies|autosomal-dominant (AD) defects
MESH:D001102 viral infections
MESH:D003324 Coronary artery disease NS
MESH:D003643 mortality|Death|died|death
MESH:D003920 diabetes|Diabetes
MESH:D004660 encephalitis
MESH:D006331 cardiac disease
MESH:D006969 deficiency of type I IFNs|type I interferonopathies
MESH:D006973 Hypertension NS|hypertension
MESH:D007153 IRF7-deficient pDCs|immunodeficiencies
MESH:D007154 immunological abnormalities
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation|Inflammation
MESH:D008171 Chronic pulmonary disease|chronic pulmonary disease|pulmonary conditions
MESH:D008180 systemic lupus erythematosus
MESH:D008661 Inborn Errors of Type I IFNs|Inborn errors of type I|inborn errors|Inborn Errors of Type I IFN|inborn errors of type I
MESH:D009080 Kawasaki disease
MESH:D009181 fungal disease
MESH:D009765 obesity
MESH:D011014 pneumonia
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 Respiratory Failure|respiratory failure
MESH:D012141 respiratory infection
MESH:D013734 autosomal-recessive (AR) defects|AR IRF7 deficiency|AR deficiencies
MESH:D015431 weight loss
MESH:D016638 critical illness|critical disease|critically ill
MESH:D016884 autoimmune polyendocrinopathy
MESH:D045169 severe diseases
 33590936
Genetic and epigenetic factors associated with increased severity of Covid-19.
Yildirim Z, et. al. (2021); Cell Biol Int; 2021 Feb 16 . doi:10.1002/cbin.11572
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|novel coronavirus pneumonia|2019 novel coronavirus diseases|SARS-CoV-2 infections|CoV-2 infection|2019-nCoV infection|SARS-CoV-2-infected|COVID-19|Coronavirus disease 2019|SARS-CoV-Infected|SARS-CoV-2 infected|SARS-Cov-2 infection|coronavirus disease-2019|Covid-19|SARS-CoV-2 Infection|coronavirus disease 2019 pneumonia|COVID19 lethality
MESH:C536170 DD
MESH:C566739 autosomal-dominant deficiencies
MESH:D000067390 cold
MESH:D000544 Alzheimer's disease
MESH:D000860 hypoxia
MESH:D001102 viral disease|viral infection|virus infection|viral infections
MESH:D001778 coagulation
MESH:D002318 cardiovascular disease
MESH:D003139 common cold
MESH:D003643 mortality|Mortality|Death|deaths|mortalities|death
MESH:D003920 diabetes|diabetes mellitus|diabetic
MESH:D003924 Type 2 diabetes
MESH:D005355 fibrosis
MESH:D006526 HCV infection|hepatitis C virus infection
MESH:D006566 B infection
MESH:D006973 hypertension
MESH:D007153 deficiency
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D007674 nondiabetic kidney disease|Collapsing glomerulopathy|Collapsing Glomerulopathy|glomerulopathy
MESH:D008180 lupus
MESH:D008661 Inborn errors of type I
MESH:D009102 multi-organ failure
MESH:D009103 familial multiple sclerosis
MESH:D009369 malignancy|cancer
MESH:D009422 neurological disorders
MESH:D011014 pneumonia|pneumonitis
MESH:D011471 prostate cancer
MESH:D012128 ARDS|acute respiratory distress syndrome|respiratory distress
MESH:D012131 respiratory failure
MESH:D012598 sclerosis
MESH:D012772 septic shock
MESH:D013927 thrombosis
MESH:D016638 critical illness|critical disease
MESH:D016893 Deficiency of IFNARs narrow
MESH:D018243 teratocarcinoma
MESH:D018352 coronavirus infections|respiratory syndrome coronavirus infection|human coronavirus infections
MESH:D018805 sepsis
MESH:D019698 chronic hepatitis C infection|chronic hepatitis C
MESH:D030342 inherited TLR3 deficiency
MESH:D045169 severe acute respiratory syndrome
MESH:D050197 atherosclerosis
MESH:D051436 chronic kidney disease
MESH:D054556 venous thromboembolism|Venous thromboembolism
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D058186 Acute kidney injury
MESH:D060085 immunodeficiency virus coinfected
 33593941
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals.
Zeberg H, et. al. (2021); Proc Natl Acad Sci U S A; 2021 Mar 02 ; 118 (9) . doi:10.1073/pnas.2026309118
MESH:C000657245 SARS-CoV-2 infection|Covid-19|COVID-19
MESH:D001102 viral infections
MESH:D003141 infectious disease|infectious diseases
MESH:D003643 Mortality|mortality
MESH:D004342 allergies
MESH:D006526 hepatitis C infections
MESH:D006527 Wilson
MESH:D007239 infections|infected|infection
MESH:D010146 pain
MESH:D012131 respiratory failure
MESH:D012859 Sjogren's syndrome
MESH:D016638 critical illness|critically ill
MESH:D045169 Severe acute respiratory syndrome
 33807915
The Role of Immunogenetics in COVID-19.
Pojero F, et. al. (2021); Int J Mol Sci; 2021 Mar 05 ; 22 (5) . doi:10.3390/ijms22052636
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|COVID-19 Disease|Coronavirus disease 19|CoV-2 infection|Coronavirus Disease 2019|CoViD-19|Covid 19|COVID-19|COVID|Coronavirus disease 2019|SARS-CoV-2 infected|SARS-Cov-2 infection|COVID-2019 infection|coronavirus disease-2019|SARS-CoV-2 Infection|coronavirus disease 19|Covid-19|COVID19+
MESH:D000068376 secondary organ dysfunction
MESH:D000077277 esophageal squamous cell carcinomas
MESH:D000079225 stress
MESH:D000163 AIDS Acquired immunodeficiency syndrome|AIDS
MESH:D000544 AD IRF7-deficiency|AD deficiencies|Alzheimer's disease|Alzheimer's Disease|AD
MESH:D000860 hypoxia
MESH:D001102 Viral Infections|viral diseases|viral infection|virus infection|viral infections
MESH:D001249 asthma|Asthma|Bronchial asthma
MESH:D001327 Autoimmune diseases|autoimmune diseases|autoimmune disorders
MESH:D001943 breast cancer
MESH:D001988 bronchiolitis
MESH:D002318 cardiovascular disease
MESH:D003141 Infectious Diseases|infectious diseases
MESH:D003371 dry cough
MESH:D003424 Crohn's disease
MESH:D003643 Mortality|mortality|deaths|died|death
MESH:D003704 dementia
MESH:D003715 Dengue fever
MESH:D003920 diabetes
MESH:D004417 dyspnoea
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D006948 hyperactivity
MESH:D006973 hypertension
MESH:D007039 AH
MESH:D007153 Deficiency
MESH:D007239 HCMV Infection|Infection|infections|infected|infection
MESH:D007249 hyper inflammation|inflammatory disorders|inflammation|Inflammatory Disease|Inflammation
MESH:D007896 leishmaniasis|Leishmania braziliensis
MESH:D007951 myeloid leukemia
MESH:D008231 lymphopenia|Lymphopenia
MESH:D008545 white melanoma
MESH:D008569 Homeostasis of Resident Memory|rules memory T
MESH:D008661 Inborn errors of type I
MESH:D009080 Kawasaki disease|Kawasaki Disease
MESH:D009081 mucolipidosis type IV
MESH:D009102 organ dysfunction|multi-organ system dysfunction
MESH:D009369 Cancer|cancer|carcinoma
MESH:D009765 obesity
MESH:D011014 pneumonia
MESH:D012128 Acute Respiratory Distress Syndrome|acute respiratory distress syndrome|ARDS|Autosomal-recessive ARDS Acute respiratory distress syndrome|respiratory distress
MESH:D012131 Respiratory Failure|Respiratory failure|respiratory impairment|respiratory failure
MESH:D012140 respiratory disease
MESH:D012409 rubella
MESH:D012769 shock
MESH:D012818 respiratory symptoms
MESH:D013734 autosomal-recessive (AR) deficiencies|AR IRF7-deficient
MESH:D014376 tuberculosis
MESH:D015179 colorectal cancer
MESH:D015212 inflammatory bowel disease
MESH:D015658 HIV infection|HIV Human immunodeficiency virus
MESH:D016470 bacteremia
MESH:D016638 critical illness|critically ill|Critically Ill
MESH:D018352 coronavirus infection|MERS
MESH:D018805 Sepsis|sepsis
MESH:D028361 mitochondrial disorder
MESH:D029424 chronic obstructive pulmonary disease|Chronic Obstructive Pulmonary Disease
MESH:D030342 genetic variation and disease|genetic defects
MESH:D045169 severe acute respiratory syndrome
MESH:D050197 Atherosclerosis|atherosclerosis
MESH:D052476 ApoE epsilon4epsilon4
MESH:D054990 idiopathic pulmonary fibrosis
MESH:D060085 secondary infections
 33934196
Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection.
Hashemi SMA, et. al. (2021); Arch Virol; 2021 May 02 . doi:10.1007/s00705-021-05070-6
MESH:C000657245 COVID-19 pneumonia|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV infection|COVID19|SARS-CoV-2 infections|novel coronavirus pneumonia|CoV-2 infection|novel coronavirus infections|SARS-CoV-2-infected|COVID-19|new coronavirus disease|SARS-CoV-1 infection Itoyama|Coronavirus disease 2019|2019 infection|SARS-CoV-1 infection outcome Patarcic|SARS-CoV-1 infection|Covid-19|coronavirus disease-2019
MESH:C535882 Johnson L
MESH:C536174 panbronchiolitis
MESH:C538614 renal cell carcinoma
MESH:C564969 multi-organ disease
MESH:C567355 immunodeficiency virus-mediated syncytia
MESH:D000544 Alzheimer's disease|Alzheimer disease
MESH:D000860 hypoxemia|hypoxia
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001424 bacterial infections
MESH:D001847 bone homeostasis
MESH:D001943 breast cancer
MESH:D002318 cardiovascular disease|cardiovascular systems|cardiovascular diseases
MESH:D002537 atherosclerotic cerebral infarction
MESH:D002544 acute cerebral infarction
MESH:D002908 rhinovirus illness
MESH:D003141 atherothrombotic disease|infectious diseases
MESH:D003428 nosocomial infection
MESH:D003643 mortality|deaths|mortalities|death|mortal
MESH:D003920 diabetes|diabetes mellitus
MESH:D003924 type 2 diabetes|type 2 diabetes mellitus
MESH:D004194 multiple diseases and disorders|numerous diseases and disorders
MESH:D004487 alveolar edema
MESH:D004646 emphysema
MESH:D004675 tick-borne encephalitis
MESH:D005355 fibrosis
MESH:D005921 glomerulosclerosis
MESH:D006331 congenital heart disease
MESH:D006333 heart failure
MESH:D006461 hemolysis
MESH:D006509 hepatitis B virus infection|hepatitis B
MESH:D006526 HCV infection|hepatitis C virus (HCV) infection|hepatitis C virus infection|hepatitis C viral infection
MESH:D006973 hypertension|hypertensive
MESH:D007239 Decreased infection|infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 Collapsing glomerulopathy|kidney disease|nondiabetic nephropathy|glomerulopathy
MESH:D008103 hepatic fibrosis
MESH:D008171 pulmonary damage|lung disease|lung damage
MESH:D008288 malaria parasites
MESH:D008545 melanoma|malignant melanoma
MESH:D008659 metabolic disorders
MESH:D008661 Inborn errors of type I
MESH:D009103 multiple sclerosis
MESH:D009336 tumour necrosis
MESH:D009362 metastasis of tumors
MESH:D009369 cancerous|cancer|cancers|tumor|carcinoma
MESH:D009393 nephritis
MESH:D010051 ovaries
MESH:D010190 invasiveness of pancreatic cancer
MESH:D010300 PD
MESH:D011014 pneumonia|lung inflammation
MESH:D011471 prostate cancer metastasis|NCI-H660 prostate cancer|prostate cancer|aggressive prostate cancer|sporadic prostate cancer
MESH:D011565 psoriasis
MESH:D011654 pulmonary edema
MESH:D011658 pulmonary fibrosis
MESH:D011660 hypoxaemic cor pulmonale
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 acute respiratory distress syndrome|ARDS|adult respiratory distress syndrome
MESH:D012131 respiratory failure|pulmonary failure
MESH:D012140 chronic respiratory disease|respiratory disease
MESH:D012141 respiratory viruses infections|upper respiratory tract infections
MESH:D012598 sclerosis
MESH:D012769 shock
MESH:D012871 skin diseases
MESH:D013927 thrombotic
MESH:D015140 vascular dementia
MESH:D015179 colorectal cancer
MESH:D015619 respiratory system edema
MESH:D015658 HIV infection|HIV-1 infection
MESH:D016638 critical illness|critically ill
MESH:D018352 MERS-CoV infection|respiratory syndrome coronavirus infection|coronavirus disease|SARS coronavirus infection|CoV-1 infection|coronavirus infection|Coronavirus infection|Middle East respiratory syndrome-coronavirus infection
MESH:D019698 chronic hepatitis C virus infection
MESH:D020258 neurotoxicity
MESH:D045169 severe acute respiratory syndrome|SARS infection
MESH:D050197 atherosclerotic|atherosclerosis|atherosclerotic lesions
MESH:D051436 chronic kidney disease
MESH:D054058 acute coronary syndrome
MESH:D054990 idiopathic pulmonary fibrosis
MESH:D055370 lung injury
MESH:D055371 acute lung failure|acute lung injury
MESH:D058186 Acute kidney injury
MESH:D059446 asplenia
 33966626
COVID-19 one year into the pandemic: from genetics and genomics to therapy, vaccination, and policy.
Novelli G, et. al. (2021); Hum Genomics; 2021 May 10 ; 15 (1) 27. doi:10.1186/s40246-021-00326-3
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|Coronavirus disease 2019|covid-gavi|SARS-CoV-2 infections|Covid|CoV-2 infection|Covid-Vac|COVID-19 disease|Covid-19|COVID-19|COVID
MESH:C535509 LV
MESH:C535882 Argentina Johnson&Johnson|Xia H, Johnson
MESH:C537769 OAS
MESH:D000080343 Torcia MG
MESH:D000163 AIDS
MESH:D000544 AD
MESH:D001102 virus infection|viral infections
MESH:D001281 AF
MESH:D001327 autoimmune diseases
MESH:D003141 Infectious Diseases|Infectious Disease|infectious diseases
MESH:D003371 dry cough
MESH:D003643 mortality|deaths|death
MESH:D003920 diabetes mellitus
MESH:D004194 multifactorial and multigenic disease
MESH:D004342 Allergy|allergic reactions
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D005862 de Oliveira T
MESH:D006261 headaches
MESH:D006467 hemophilia|Hemophilia growth
MESH:D007239 Infection|infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 kidney diseases
MESH:D008171 lung disease
MESH:D008661 Inborn errors of type I
MESH:D009207 MJ
MESH:D009223 DM
MESH:D009369 cancer
MESH:D009422 neurological disorders
MESH:D009765 obese
MESH:D011014 pneumonia
MESH:D012128 Acute respiratory distress syndrome|acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory epithelia|respiratory failure
MESH:D012872 Tegally H, Wilkinson E
MESH:D015658 HIV|HIV-1 infection
MESH:D016638 critical illness
MESH:D018352 coronavirus infections|respiratory syndrome coronavirus infection|MERS|SARS coronavirus infection|Middle East respiratory syndrome
MESH:D020181 Obstructive sleep apnea syndrome|obstructive sleep apnea syndrome
MESH:D029424 Chronic obstructive pulmonary disease|chronic obstructive pulmonary disease|COPD
MESH:D063806 myalgia
rs10735810
/
: 2
 32480226
Effects of host genetic variations on response to, susceptibility and severity of respiratory infections.
Ghafouri-Fard S, et. al. (2020); Biomed. Pharmacother.; 2020 Aug ; 128 110296. doi:10.1016/j.biopha.2020.110296
MESH:C000657245 CoV-2 infection|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV infection|COVID-19
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001988 bronchiolitis|TLR9 Bronchiolitis
MESH:D003141 infectious diseases
MESH:D003643 mortality|death
MESH:D007239 RSV infection|infections|infection|infected
MESH:D009369 cancer
MESH:D009461 dysfunction
MESH:D011008 Pneumococcal disease|Pneumococcal diseases
MESH:D011014 pneumonia
MESH:D012120 acute respiratory syndrome coronavirus infection
MESH:D012128 Acute respiratory distress syndrome|TNFalpha ARDS|acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory disorders
MESH:D012141 respiratory tract infections|respiratory infections
MESH:D012772 Septic shock|Pneumococcal septic shock|septic shock
MESH:D014376 Tuberculosis|tuberculosis
MESH:D014397 pulmonary tuberculosis|Pulmonary tuberculosis
MESH:D016638 septic pediatric critically ill
MESH:D018352 respiratory syndrome coronavirus infection
MESH:D018805 Sepsis|sepsis
 33184476
Genetic influences on viral-induced cytokine responses in the lung.
Forbester JL, et. al. (2020); Mucosal Immunol; 2020 Nov 12 . doi:10.1038/s41385-020-00355-6
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-infected|novel coronavirus pneumonia|SARS-CoV-2 disease|SARS-CoV-2-infected|Covid-19|COVID-19
MESH:C536395 HSV-1 encephalitis
MESH:C536528 hyper-responsive LPS|hyper-responsive LPS phenotypeLocated
MESH:D000079225 damage stress
MESH:D000081207 Primary immunodeficiencies|primary immunodeficiency disorders
MESH:D000163 AIDS
MESH:D001102 virus disease|viral diseases|pulmonary viral infections|viral infections|viral disease|Viral infections|viral lung infection|virus infections|virus infection|viral infection
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma|allergic asthma
MESH:D001327 autoimmune disease
MESH:D001988 RSV bronchiolitis|bronchiolitis|RSV-bronchiolitis|virus bronchiolitis
MESH:D002318 cardiovascular disease
MESH:D002908 rhinovirus illness
MESH:D003139 common diseases
MESH:D003141 infectious disease|IAV disease|infectious diseases
MESH:D003643 mortality|died|deaths|death
MESH:D003645 sudden death
MESH:D003920 diabetes
MESH:D004802 lung eosinophilia
MESH:D005334 fever
MESH:D007153 deficiency|immunodeficiencies|immunodeficiency
MESH:D007239 Infection|Infections|RSV-infected|IAV infection|infections|infection|infected
MESH:D007249 allergic inflammation|inflammation|inflammation post-IAV infection
MESH:D008171 lung disease|lung damage
MESH:D008180 systemic lupus erythematosus
MESH:D008661 Inborn errors of type I|inborn errors
MESH:D009102 multiple organ failure|hypercytokinaemia with multiorgan failure
MESH:D009336 tumour necrosis
MESH:D009765 obesity
MESH:D011014 lung inflammatory disease|pneumonia|pneumonitis|lung inflammation|pulmonary inflammation
MESH:D011657 pulmonary eosinophilia
MESH:D012120 respiratory syndromes
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 infection decreases lung injury|respiratory dysfunction
MESH:D012140 Respiratory Disease|respiratory diseases|respiratory disease
MESH:D012141 respiratory tract infections|pulmonary infections|respiratory infections
MESH:D012772 septic shock
MESH:D015047 zoonotic
MESH:D015212 inflammatory bowel disease
MESH:D015431 weight loss
MESH:D015658 HIV-1 infection
MESH:D016638 Critically
MESH:D018357 respiratory syncytial virus infection|Respiratory syncytial virus infection|respiratory syncytial virus disease|Respiratory syncytial virus disease
MESH:D018980 Williams
MESH:D030342 inherited IRF9 deficiency
MESH:D045169 severe acute respiratory syndrome
MESH:D051359 haemophagocytic lymphohistiocytosis
MESH:D052456 TLR4 hypo-responsiveness
MESH:D054066 NK cell deficiency
MESH:D055370 lung injury
MESH:D055501 pulmonary macrophage
MESH:D058606 TLR3-pathway deficiencies
MESH:D060085 coinfection|bacterial co-infection
MESH:D061325 hyperinflammatory syndrome
OMIM:613661 iPS-DCs and iPSDMs
rs10741657 Affx-4577802
A/G
LOC107984314 107984314 11:14893332 1
 33537824
Potential immunomodulatory effects of vitamin D in the prevention of severe coronavirus disease 2019: An ally for Latin America (Review).
Turrubiates-Hernández FJ, et. al. (2021); Int J Mol Med; 2021 04 ; 47 (4) . doi:10.3892/ijmm.2021.4865
MESH:C000657245 covid-19|COVID-19 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|novel coronavirus pneumonia|2019 infection|COVID Quasi|CoV-2 infection|2019-nCoV infection|cOVID-19|COVID-19|COVID|new coronavirus disease
MESH:C565301 25(OH)D deficiency|25(OH)DNephrotic syndrome
MESH:D000071069 dry conditions
MESH:D000309 insufficiency/deficiency|insufficiency
MESH:D001171 still deficiencies
MESH:D001172 rheumatoid arthritis
MESH:D001327 autoimmune diseases
MESH:D001991 bronchitis
MESH:D002277 guias alimentarias para
MESH:D002318 cardiovascular disease
MESH:D002908 chronic diseases
MESH:D003398 CRS
MESH:D003550 cystic fibrosis
MESH:D003643 mortality|Mortality|deaths|death|mortal
MESH:D003920 diabetes
MESH:D004403 diarrheal disease
MESH:D004421 Excess 1,25(OH)2D
MESH:D004681 autoimmune encephalomyelitis
MESH:D004827 epilepsy
MESH:D005862 Brasileira de Endocrinologia e Metabologia|Deficiencia de vitamina
MESH:D006333 25(OH)DLiver failure
MESH:D006934 hypercalcemia
MESH:D006973 hypertension
MESH:D007239 infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 glomerular diseases|Kidney Disease|kidney disease
MESH:D008180 systemic lupus erythe-matosus-the hype|systemic lupus erythematosus
MESH:D008286 malabsorption syndromes|intestinal malabsorption syndromes
MESH:D009102 multiple organ failure|multiple organ damage
MESH:D009369 cancer
MESH:D009404 nephrotic syndrome
MESH:D009765 obesity
MESH:D010018 osteomalacia
MESH:D010859 skin pigmentation|skin cancerSkin pigmentation
MESH:D011014 pneumonia
MESH:D011507 proteinuria Decreased synthesis of 1,25(OH)2DChronic kidney disease
MESH:D012120 respiratory syndrome
MESH:D012128 Acute respiratory distress syndrome|acute respiratory distress syndrome|ARDS|acute lung injury and the acute respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory illnesses
MESH:D012141 acute respiratory tract infection|respiratory infection|acute respiratory tract infections|upper respiratory infection|respiratory tract infections|respiratory infections
MESH:D012778 short bowel syndrome
MESH:D012818 respiratory symptoms
MESH:D013471 sunburn
MESH:D014397 pulmonary tuberculosis
MESH:D015212 inflammatory bowel disease
MESH:D016638 critically ill
MESH:D017093 liver failure
MESH:D018352 respiratory syndrome coronavirus infection|coronavirus disease|MERS|Middle East respiratory syndrome
MESH:D051437 Decreased renal mass
MESH:D054740 tolerogenic dendritic cell
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D058625 deficiency in chronic liver disease|Chronic liver disease Decreased hydroxylation
rs1074637
T/C
TANC2 26115 17:63365469 1
 33349849
The effect of angiotensin-converting enzyme levels on Covid-19 susceptibility and severity: a Mendelian randomization study.
Butler-Laporte G, et. al. (2020); Int J Epidemiol; 2020 Dec 08 . doi:10.1093/ije/dyaa229
MESH:C000657245 covid-19|SARS-CoV-2 infection|coronavirus disease 2019|Coronavirus disease 2019|Covid-19|Covid-19-infected|COVID-19
MESH:D002318 cardiovascular system|cardiovascular diseases|cardiovascular-disease
MESH:D003141 infectious-disease|infectious disease
MESH:D003643 mortality|died|death
MESH:D003920 diabetes mellitus|diabetes
MESH:D006333 heart failure
MESH:D006973 Hypertension|hypertension
MESH:D007239 infections|infection
MESH:D008310 Classification of Diseases
MESH:D009203 myocardial infarction
MESH:D009369 Cancer
MESH:D010003 EA/OA EAF
MESH:D012131 respiratory failure
MESH:D045169 severe disease
rs10754558
G/C,T
NLRP3 114548 1:247448734 1
 33584697
Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective.
();
MESH:C000657245 Coronavirus Disease 2019|SARS-CoV-2 infection|coronavirus disease-2019|COVID-19
MESH:D000069279 drug-resistant epilepsy
MESH:D000070642 traumatic brain injury
MESH:D000072716 cancer pain
MESH:D000079225 Stress
MESH:D000224 Addison's Disease|Addison's disease|Addison's Skin inflammation
MESH:D000275 depression
MESH:D000544 Alzheimer|Alzheimer's disease|Alzheimer's like disease|Alzheimer-like disease|Alzheimer's Disease|AD|Alzheimer disease
MESH:D001007 anxiety
MESH:D001018 aortic occlusive disease
MESH:D001168 polyarthritis|Arthritis|Polyarthritis|arthritis
MESH:D001172 rheumatoid arthritis|RA
MESH:D001228 Aspergillus infection
MESH:D001249 asthma
MESH:D001327 autoimmune diseases|autoimmune disorders
MESH:D001424 bacterial infections
MESH:D001523 behavioral deficits
MESH:D002189 Cannabis Withdrawal Syndrome
MESH:D002294 cutaneous squamous cell carcinoma
MESH:D002318 cardiovascular disease|cardiovascular diseases|Cardiovascular disorders|Cardiovascular Disease
MESH:D002375 catalepsy
MESH:D002544 ischemic stroke
MESH:D002598 Chagas cardiomyopathy
MESH:D003092 colitis|Colitis
MESH:D003324 coronary artery disease|Coronary Artery Disease
MESH:D003424 Crohn's disease
MESH:D003643 mortality
MESH:D003704 dementia|Dementia
MESH:D003920 diabetics|diabetes|diabetic|diabetic inflammation|normoglycemia Zucker diabetic fatty|Zucker diabetic fatty|Diabetes
MESH:D003922 Type-1 diabetes|type-1 diabetes|Type 1 Diabetes|type-1 diabetes and celiac disease
MESH:D003924 Type-2 diabetes|Type 2 Diabetes|type 2 diabetes|type-2 diabetes
MESH:D003928 diabetic nephropathy Yes Rheumatoid Arthritis|Diabetic Nephropathy|diabetic nephropathy|diabetic kidney disease
MESH:D004487 swelling
MESH:D004681 autoimmune encephalomyelitis
MESH:D004827 epileptic encephalopathy|epileptic spasms
MESH:D005234 steatohepatitis High|steatohepatitis|alcoholic fatty liver disease|non-alcoholic steatohepatitis
MESH:D005355 fibrosis
MESH:D006073 gout
MESH:D006086 graft-versus-host disease
MESH:D006333 MI heart failure
MESH:D006973 hypertensive sclerosis
MESH:D007239 Infections|infections|infection|infected
MESH:D007249 Inflammasome-Mediated Chronic Inflammation|inflammation of joints|Inflammation|inflammatory diseases|inflammatory disorders|inflammation|skin inflammation|Inflammatory Disorders|neuro-inflammation|inflammatory disease|liver inflammation
MESH:D007340 beta cell dysfunction
MESH:D007674 nephropathy|renal disorders|Kidney Diseases
MESH:D008175 lung cancer
MESH:D008180 Systemic Lupus Erythematosus|Systemic lupus erythematosus|systemic lupus erythematosus|SLE
MESH:D008545 Melanoma 2 proteins|malignant melanoma
MESH:D008569 memory impairment in Alzheimer-like disease|memory impairment and neuroinflammation|memory impairment
MESH:D008659 metabolic disorders
MESH:D009103 multiple sclerosis
MESH:D009128 spasticity
MESH:D009190 myelodysplastic syndrome
MESH:D009203 Myocardial Infarction|Myocardial infarction|myocardial infarction
MESH:D009325 nausea
MESH:D009336 necrosis
MESH:D009369 Cancer|cancerous|cancer|cancers|tumor|Cancers
MESH:D009410 axonal degeneration and neuroinflammation|neuronal death|neuronal pyroptosis|axonal degeneration
MESH:D009422 neurological disorders
MESH:D009437 Neuropathic Pain
MESH:D009765 obese|obesity
MESH:D010146 pain|Pain
MESH:D010300 Parkinsons' disease|PD|Parkinson's disease
MESH:D010505 periodic syndrome
MESH:D011507 Proteinuria
MESH:D011537 chronic itch
MESH:D011565 psoriasis
MESH:D012080 CKD
MESH:D012421 rupture
MESH:D012480 Salmonella infection
MESH:D012516 osteosarcoma
MESH:D012559 Schizophrenia|schizophrenia
MESH:D012595 systemic sclerosis
MESH:D012598 sclerosis
MESH:D012640 seizures
MESH:D012772 endotoxic shock
MESH:D012829 silicosis
MESH:D012871 dry skin
MESH:D012878 skin cancers|skin cancer
MESH:D014125 congenital toxoplasmosis
MESH:D014355 Trypanosoma cruzi seropositive
MESH:D014402 tuberous sclerosis|tuberous sclerosis complex
MESH:D014839 vomiting
MESH:D015179 microsatellite unstable colon cancers|colorectal and small bowel cancer
MESH:D015212 inflammatory bowel disease|Inflammatory Bowel Diseases|IBD|Inflammatory bowel disease
MESH:D016638 critically ill
MESH:D016883 DKA|Diabetic Ketoacidosis
MESH:D017544 abdominal aneurysmal and occlusive aortic disease
MESH:D019636 neurodegenerative disorders|neurodegenerative diseases|Neurodegenerative Diseases|neurodegeneration|neurodegenerative
MESH:D020078 augments neuroinflammation
MESH:D020258 neurotoxicity
MESH:D020295 mesencephalic neurons
MESH:D020521 stroke
MESH:D023921 coronary stenosis
MESH:D029424 chronic obstructive pulmonary disorder|COPD
MESH:D050197 atherosclerotic|atherosclerosis
MESH:D051271 SLE symptoms
MESH:D051436 chronic kidney disease
MESH:D054058 coronary syndrome
MESH:D054990 idiopathic pulmonary fibrosis
MESH:D056587 Cryopyrin-Associated Periodic Syndrome|familial cold autoinflammatory syndrome
MESH:D056660 systemic autoinflammatory disease|autoinflammatory diseases|autosomal-dominant autoinflammatory disorder
MESH:D058065 diabetic cardiomyopathy
MESH:D058186 acute kidney injury
MESH:D064420 cytotoxicity|Cytotoxicity
MESH:D065626 nonalcoholic fatty liver disease
MESH:D065768 Lennox-Gastaut
OMIM:191900 Muckle-Wells syndrome
rs10757212
G/A
LOC107987053 107987053 9:21304804 1
 33184476
Genetic influences on viral-induced cytokine responses in the lung.
Forbester JL, et. al. (2020); Mucosal Immunol; 2020 Nov 12 . doi:10.1038/s41385-020-00355-6
MESH:C000657245 SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-infected|novel coronavirus pneumonia|SARS-CoV-2 disease|SARS-CoV-2-infected|Covid-19|COVID-19
MESH:C536395 HSV-1 encephalitis
MESH:C536528 hyper-responsive LPS|hyper-responsive LPS phenotypeLocated
MESH:D000079225 damage stress
MESH:D000081207 Primary immunodeficiencies|primary immunodeficiency disorders
MESH:D000163 AIDS
MESH:D001102 virus disease|viral diseases|pulmonary viral infections|viral infections|viral disease|Viral infections|viral lung infection|virus infections|virus infection|viral infection
MESH:D001172 rheumatoid arthritis
MESH:D001249 asthma|allergic asthma
MESH:D001327 autoimmune disease
MESH:D001988 RSV bronchiolitis|bronchiolitis|RSV-bronchiolitis|virus bronchiolitis
MESH:D002318 cardiovascular disease
MESH:D002908 rhinovirus illness
MESH:D003139 common diseases
MESH:D003141 infectious disease|IAV disease|infectious diseases
MESH:D003643 mortality|died|deaths|death
MESH:D003645 sudden death
MESH:D003920 diabetes
MESH:D004802 lung eosinophilia
MESH:D005334 fever
MESH:D007153 deficiency|immunodeficiencies|immunodeficiency
MESH:D007239 Infection|Infections|RSV-infected|IAV infection|infections|infection|infected
MESH:D007249 allergic inflammation|inflammation|inflammation post-IAV infection
MESH:D008171 lung disease|lung damage
MESH:D008180 systemic lupus erythematosus
MESH:D008661 Inborn errors of type I|inborn errors
MESH:D009102 multiple organ failure|hypercytokinaemia with multiorgan failure
MESH:D009336 tumour necrosis
MESH:D009765 obesity
MESH:D011014 lung inflammatory disease|pneumonia|pneumonitis|lung inflammation|pulmonary inflammation
MESH:D011657 pulmonary eosinophilia
MESH:D012120 respiratory syndromes
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 infection decreases lung injury|respiratory dysfunction
MESH:D012140 Respiratory Disease|respiratory diseases|respiratory disease
MESH:D012141 respiratory tract infections|pulmonary infections|respiratory infections
MESH:D012772 septic shock
MESH:D015047 zoonotic
MESH:D015212 inflammatory bowel disease
MESH:D015431 weight loss
MESH:D015658 HIV-1 infection
MESH:D016638 Critically
MESH:D018357 respiratory syncytial virus infection|Respiratory syncytial virus infection|respiratory syncytial virus disease|Respiratory syncytial virus disease
MESH:D018980 Williams
MESH:D030342 inherited IRF9 deficiency
MESH:D045169 severe acute respiratory syndrome
MESH:D051359 haemophagocytic lymphohistiocytosis
MESH:D052456 TLR4 hypo-responsiveness
MESH:D054066 NK cell deficiency
MESH:D055370 lung injury
MESH:D055501 pulmonary macrophage
MESH:D058606 TLR3-pathway deficiencies
MESH:D060085 coinfection|bacterial co-infection
MESH:D061325 hyperinflammatory syndrome
OMIM:613661 iPS-DCs and iPSDMs
rs10759932 Affx-33154062
T/C
TLR4 7099 9:117702866 1
 33763088
Germline Genetic Variants of Viral Entry and Innate Immunity May Influence Susceptibility to SARS-CoV-2 Infection: Toward a Polygenic Risk Score for Risk Stratification.
Grolmusz VK, et. al. (2021); Front Immunol; 2021 ; 12 653489. doi:10.3389/fimmu.2021.653489
MESH:C000657245 SARS-CoV-2 infection|SARS-CoV-2 Infection|Covid-19|COVID-19
MESH:D000071074 neonatal sepsis
MESH:D000072742 invasive fungal disease
MESH:D000077273 papillary thyroid carcinoma
MESH:D000152 acne vulgaris
MESH:D000292 pelvic inflammatory disease
MESH:D001015 takayasu arteritis
MESH:D001102 virus infection|viral infections
MESH:D001167 arteritis
MESH:D001168 arthritis
MESH:D001172 rheumatoid arthritis|RA
MESH:D001249 asthma|Asthma
MESH:D001281 atrial fibrillation
MESH:D001327 Autoimmune diseases|autoimmune diseases|Autoimmune disorders|autoimmune disorders
MESH:D001943 breast cancer
MESH:D001989 bronchiolitis obliterans syndrome
MESH:D002181 vulvovaginal candidiasis
MESH:D002294 squamous cell carcinoma|cervical squamous cell carcinoma
MESH:D002311 Dilated cardiomyopathy|DCM|dilated cardiomyopathy|hypertrophic and dilated cardiomyopathies
MESH:D002318 cardiovascular disorders|cardiovascular and metabolic diseases|Cardiovascular death|cardiovascular events
MESH:D002446 celiac disease
MESH:D002544 ischaemic stroke|ischemic stroke|Ischemic stroke
MESH:D002690 Chlamydia trachomatis infection
MESH:D002908 chronic diseases
MESH:D003110 colon
MESH:D003141 infectious diseases
MESH:D003324 coronary artery disease|Coronary artery disease N
MESH:D003371 dry cough
MESH:D003424 Crohn's disease
MESH:D003556 cystitis
MESH:D003586 cytomegalovirus infection|congenital cytomegalovirus (CMV) infection
MESH:D003643 mortality|death
MESH:D003920 diabetes|Diabetic retinopathy|diabetes mellitus
MESH:D003924 type 2 diabetes mellitus
MESH:D004417 dyspnea
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D005759 gastroenteritis
MESH:D005910 glioma
MESH:D006111 Graves' disease
MESH:D006509 HBV-infected|chronic HBV infection|hepatitis B|hepatitis B virus infection
MESH:D006526 HCV infection|hepatitis C virus infection|hepatitis C virus
MESH:D006528 hepatocellular carcinoma|liver cancer
MESH:D006689 Hodgkin lymphoma|hodgkin lymphoma
MESH:D006973 Hypertension|hypertension|hypertensive left ventricular hypertrophy
MESH:D007037 hypothyroidism
MESH:D007239 tuberculosis infection|CMV infection|infections|infected|infection
MESH:D007249 inflammation|Inflammation
MESH:D007319 initiation of the disease
MESH:D007674 IgA nephropathy|nephropathy
MESH:D008107 liver diseases
MESH:D008175 lung cancer
MESH:D008180 systemic lupus|lupus erythematosus|male systemic lupus erythematosus|systemic lupus erythematosus|SLE
MESH:D008181 lupus nephritis
MESH:D008193 Lyme disease
MESH:D008228 non-hodgkin's lymphoma|non-hodgkin lymphoma|non-Hodgkin lymphoma
MESH:D008288 malaria|malaria infection
MESH:D008545 melanoma|melanoma malignum
MESH:D008589 meningococcal
MESH:D008661 Inborn errors of type I
MESH:D008947 MCTD
MESH:D009059 mouth disease
MESH:D009102 sepsis-related organ failure
MESH:D009103 multiple sclerosis|Multiple sclerosis
MESH:D009336 tumour necrosis|tumor necrosis
MESH:D009369 malignant disorder|cancer|cancers|carcinoma|tumors
MESH:D009386 Neoplastic diseases|neoplastic diseases
MESH:D009765 obesity
MESH:D010003 osteoarthritis
MESH:D010031 otitis
MESH:D010300 's disease
MESH:D010518 periodontitis|aggressive periodontitis
MESH:D010859 pigmentation
MESH:D011014 pneumonia
MESH:D011471 advanced prostate cancer|prostate cancer
MESH:D011565 psoriasis|psoriasis vulgaris
MESH:D012128 acute respiratory distress syndrome|ARDS
MESH:D012131 respiratory failure
MESH:D012162 degeneration
MESH:D012164 retinopathy
MESH:D012409 rubella|rubella vaccination
MESH:D012507 sarcoidosis
MESH:D012559 Schizophrenia|schizophrenia
MESH:D012595 systemic sclerosis
MESH:D013167 ankylosing spondylitis
MESH:D013274 gastric cancer
MESH:D013700 giant cell arteritis
MESH:D013964 thyroid cancer
MESH:D014376 tuberculosis|tuberculosis disease
MESH:D014397 pulmonary tuberculosis
MESH:D015179 colorectal cancer|CRC
MESH:D015470 acute myeloid leukaemia|acute myeloid leukemia|AML
MESH:D015535 psoriatic arthritis
MESH:D015658 vaginosis in HIV-infected|HIV-1 infected|HIV infection|HIV-1 infected adolescents|HIV-1 infection|HIV infections
MESH:D016585 bacterial vaginosis
MESH:D016638 critical illness
MESH:D016920 bacterial
MESH:D017093 hepatic organ failure
MESH:D017359 preeclampsia and HELLP syndrome
MESH:D017379 Left ventricular hypertrophy
MESH:D018357 respiratory syncytial virus disease
MESH:D018442 marginal zone lymphoma
MESH:D018805 sepsis
MESH:D020521 stroke
MESH:D024821 Metabolic syndrome|metabolic syndrome
MESH:D030342 congenital CMV disease
MESH:D030361 papillomavirus-16 infection
MESH:D043183 irritable bowel syndrome
MESH:D049970 Graves' ophthalmopathy|ophthalmopathy
MESH:D050197 atherosclerotic
MESH:D054058 acute coronary syndrome|coronary syndrome
MESH:D054990 idiopathic pulmonary fibrosis
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D055732 cavitary pulmonary aspergillosis|pulmonary aspergillosis
MESH:D055744 invasive aspergillosis
MESH:D065632 chikungunya virus infection
rs10763962
C/T
LINC00838 100505583 10:33927825 1
 32909007
Determinants of SARS-CoV-2 receptor gene expression in upper and lower airways.
Aliee H, et. al. (2020); medRxiv; 2020 Sep 02 . doi:10.1101/2020.08.31.20169946
MESH:C000656865 logFC P Value logFC P Value logFC P Value logFC P Value logFC P|logFC P Value logFC P Value logFC P
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV-2 infections|novel coronavirus pneumonia|COVID infection|CoV-2 infection|Coronavirus Disease 2019 Pneumonia|novel coronavirus 2019|Covid-19|COVID-19|2019 Novel Coronavirus-Infected Pneumonia|COVID
MESH:C565427 lymphopenic
MESH:D000860 hypoxemia
MESH:D001249 asthma
MESH:D001988 bronchiolitis
MESH:D002318 cardiovascular disease
MESH:D003371 cough
MESH:D003643 mortality|Mortality|Death
MESH:D003920 diabetes
MESH:D003967 diarrhea
MESH:D004417 dyspnea
MESH:D005221 fatigue
MESH:D005334 fever
MESH:D006965 hyperplasia
MESH:D006973 hypertension
MESH:D007239 Infection|infected|infection
MESH:D007249 inflammatory diseases|inflammation
MESH:D008171 lung disease
MESH:D008173 obstructive pulmonary diseases
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D011014 Pneumonia
MESH:D012128 Acute Respiratory Distress Syndrome|acute respiratory distress syndrome|ARDS
MESH:D012131 Respiratory Failure|respiratory failure
MESH:D012140 respiratory diseases
MESH:D012141 upper airway infection|respiratory infections
MESH:D013927 thrombosis
MESH:D017093 liver injury
MESH:D018352 coronavirus tropism
MESH:D063129 parental asthma
MESH:D063806 myalgia
rs10774671
G/A,C
OAS1 4938 12:112919388 3
 21638280
2'-5' oligoadenylate synthetase 1 polymorphism is associated with prostate cancer.
Mandal S, et. al. (2011); Cancer; 2011 Dec 15; 117(24) 5509-18. doi:10.1002/cncr.26219
MESH:C000657245 SARS-CoV infection
MESH:C537243 hereditary prostate cancer
MESH:C538184 AFD
MESH:C565201 sporadic aggressive prostate carcinoma
MESH:D001102 viral infection
MESH:D003920 diabetes
MESH:D003922 sclerosis and type I diabetes|Type 1 diabetes
MESH:D006323 growth arrest
MESH:D006526 hepatitis C virus infection
MESH:D007239 infections|infection
MESH:D008103 OAS-1 determines liver fibrosis
MESH:D009103 multiple sclerosis
MESH:D009369 Cancer|KU Cancer|cancer|tumor|cancers|Cancers
MESH:D011471 prostate cancer|Prostate cancer|prostate cancer disease|Prostate Cancer|sporadic prostate cancer
MESH:D012410 congenital rubella virus infection
MESH:D012598 sclerosis
MESH:D014901 West Nile virus infection
MESH:D018357 respiratory syncytial virus infection
MESH:D020022
 33593941
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals.
Zeberg H, et. al. (2021); Proc Natl Acad Sci U S A; 2021 Mar 02 ; 118 (9) . doi:10.1073/pnas.2026309118
MESH:C000657245 SARS-CoV-2 infection|Covid-19|COVID-19
MESH:D001102 viral infections
MESH:D003141 infectious disease|infectious diseases
MESH:D003643 Mortality|mortality
MESH:D004342 allergies
MESH:D006526 hepatitis C infections
MESH:D006527 Wilson
MESH:D007239 infections|infected|infection
MESH:D010146 pain
MESH:D012131 respiratory failure
MESH:D012859 Sjogren's syndrome
MESH:D016638 critical illness|critically ill
MESH:D045169 Severe acute respiratory syndrome
 33791713
Alternative splicing of OAS1 alters the risk for severe COVID-19.
Huffman J, et. al. (2021); medRxiv; 2021 Mar 25 . doi:10.1101/2021.03.20.21254005
MESH:C000657245 SARS-CoV-2 infection|Covid-19|COVID-19|COVID
MESH:D003643 died
MESH:D007239 infection
MESH:D008661 Inborn errors of type I
MESH:D012131 Respiratory Failure|respiratory failure
MESH:D016638 critical illness|critically ill
rs10794307
C/T
IFITM3 10410 11:322722 1
 33101356
Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene Variants.
Iyer GR, et. al. (2020); Front Genet; 2020 ; 11 861. doi:10.3389/fgene.2020.00861
MESH:C000657245 covid-19|SARS-CoV-2 infection|COVID19|novel coronavirus disease|COVID-19
MESH:C536174 panbronchiolitis
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001249 asthma
MESH:D001988 bronchiolitis
MESH:D002318 cardiovascular disorders
MESH:D003092 colitis
MESH:D003141 infectious diseases
MESH:D003229 conjunctival infection
MESH:D003586 cytomegalovirus disease
MESH:D003643 mortality
MESH:D003715 dengue fever
MESH:D003920 diabetes|diabetes mellitus
MESH:D004342 allergic
MESH:D004417 shortness of breath
MESH:D004675 tick-borne encephalitis
MESH:D005355 fibrosis
MESH:D006333 chronic heart failure
MESH:D006965 hyperplasia
MESH:D007239 establishing infections|infections|infection|infected
MESH:D007249 inflammation
MESH:D008171 lung abnormalities|lung disease|lung diseases
MESH:D009080 Kawasaki disease
MESH:D011009 pneumoconiosis
MESH:D011471 prostate cancer
MESH:D011658 pulmonary fibrosis
MESH:D012128 respiratory distress
MESH:D012131 respiratory disorders|respiratory failure
MESH:D012140 respiratory illness
MESH:D012141 upper respiratory infection
MESH:D014376 tuberculosis
MESH:D014397 pulmonary tuberculosis
MESH:D015179 colorectal cancer
MESH:D015658 HIV-1 infection
MESH:D018352 coronavirus disease|MERS|Middle East Respiratory Syndrome
MESH:D018980 Williams
MESH:D020521 stroke
MESH:D030342 genetic disease
MESH:D054243 vesicular stomatitis virus infection
MESH:D054990 idiopathic pulmonary fibrosis|Idiopathic pulmonary fibrosis
MESH:D055371 acute lung injury
MESH:D055744 invasive pulmonary aspergillosis infection|invasive pulmonary Aspergillosis infection
MESH:D058625 end-stage lung disease
MESH:D064420 memory Cytotoxic T
rs10830963 Affx-6373733
C/G
MTNR1B 4544 11:92975544 1
 32992875
Targeting Host Defense System and Rescuing Compromised Mitochondria to Increase Tolerance against Pathogens by Melatonin May Impact Outcome of Deadly Virus Infection Pertinent to COVID-19.
Tan DX, et. al. (2020); Molecules; 2020 Sep 25 ; 25 (19) . doi:10.3390/molecules25194410
MESH:C000657245 covid-19|SARS-CoV-2 infection|coronavirus disease 2019|Coronavirus disease 2019|Coronavirus Disease 2019|Covid-19|COVID-19|coronavirus disease 2019 pneumonia
MESH:C537182 IVF
MESH:C537277 glycosyl phosphatidylinositol anchored
MESH:C564971 inborne disadvantage concerning mitochondria
MESH:C567425 endocrinopathies
MESH:D000067390 cold
MESH:D000079225 stresses|cold stress
MESH:D000544 Alzheimer's disease
MESH:D000690 amyotrophic lateral sclerosis
MESH:D000860 anoxia|hypoxia|tumor hypoxia
MESH:D001102 virus disease|viral diseases|Virus infection|Viral Infection|viral infections|enteritis virus infection|Virus Infection|Deadly Virus Infection|virus infections|virus infection|viral infection|viral infectious diseases|deadly virus infections
MESH:D001327 autoimmune diseases
MESH:D001523 psychiatric disease
MESH:D001778 blood coagulation
MESH:D001930 injuries of brain|hypoxic-ischemic brain injury
MESH:D001943 breast cancer|breast and prostate cancers
MESH:D002114 calcification
MESH:D002318 cardiovascular disorders|cardiovascular disease|cardiovascular diseases
MESH:D002545 cerebral ischemia
MESH:D003072 neuroinflammation and cognitive dysfunction
MESH:D003141 infectious disease|infectious diseases
MESH:D003586 cytomegalovirus infection
MESH:D003643 mortality|deaths|cardiac death|death
MESH:D003645 sudden death
MESH:D003920 diabetes|diabetes mellitus|diabetic|Diabetes
MESH:D004660 encephalitis
MESH:D005171 Factor VIIa
MESH:D006331 heart disease|heart diseases|cardiac microvascular ischemia-reperfusion injury|cardiac ischemia
MESH:D006461 hemolysis
MESH:D006525 hepatitis virus infections
MESH:D006526 infections by hepatitis C
MESH:D006528 hepatoma|cancer stemness of hepatocellular carcinoma cells via glycolysis metabolism
MESH:D006973 hypertension
MESH:D007153 Melatonin deficiency|melatonin deficiency
MESH:D007238 heart infarction
MESH:D007239 Infection|infections|asiaticus infected|infection|infected
MESH:D007249 inflammation|Inflammation
MESH:D007410 intestinal injury
MESH:D007511 intestinal ischemia|ischemia
MESH:D007674 nephropathies
MESH:D008545 melanoma cells
MESH:D008569 memory deficits
MESH:D008659 metabolic disorders
MESH:D009135 myopathies
MESH:D009181 fungal infections
MESH:D009202 myocardial injury|myocardial damage
MESH:D009203 acute myocardial infarction|myocardial infarction
MESH:D009369 cancer|tumor
MESH:D009422 neurological damage
MESH:D009461 dysfunctional
MESH:D009765 obesity|obese
MESH:D010048 multiple ovarian cysts
MESH:D010195 pancreatic beta-cell loss due to glucotoxicity
MESH:D010300 Parkinson disease|Parkinson's disease
MESH:D010510 periodontal diseases
MESH:D011236 prediabetes
MESH:D011782 tetraplegia
MESH:D012140 respiratory diseases|damage the mitochondrial respiratory metabolism|respiratory metabolism
MESH:D012409 rubella
MESH:D012640 fitness
MESH:D012771 Ebola hemorrhagic shock syndrome
MESH:D013923 Thromboembolism|Thromboembolic
MESH:D013927 vascular thrombosis|Thrombosis|thrombotic catastrophe|thrombosis
MESH:D015427 ischemia/reperfusion injury
MESH:D015428 myocardial ischemia-reperfusion injury
MESH:D015658 immunodeficiency viruses (HIV) infected|HIV-1-infected
MESH:D016638 critical illness
MESH:D017093 liver mitochondria|fulminant hepatic failure
MESH:D017379 left ventricular hypertrophy
MESH:D018352 MERS
MESH:D019636 Neurodegeneration|neurodegenerative diseases|neurodegeneration
MESH:D020244 malignant middle cerebral artery infarction
MESH:D020246 venous thrombosis
MESH:D020271 neurological diseases
MESH:D020734 parkinsonian
MESH:D028361 mitochondrial damage|Mitochondrial dysfunction|mitochondrial dysfunction|mitochondrial injury|Mitochondrial diseases
MESH:D030401 melatonin deficiency favors cytochrome C
MESH:D044882 glucose metabolism
MESH:D050197 atherosclerosis
MESH:D055370 lung injury
MESH:D060825 impaired early insulin secretion
MESH:D064420 cytotoxicity
MESH:D066126 cardiotoxicity
rs10842898
G/C,T
KLRG1 10219 12:9109693 1
 32747830
Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection.
Ramlall V, et. al. (2020); Nat. Med.; 2020 Aug 03 . doi:10.1038/s41591-020-1021-2
MESH:C000657245 CoV-2 infection|SARS-CoV-2 infection|coronavirus disease 2019|SARS-CoV-2-infected|Covid-19|COVID-19|COVID
MESH:D000782 aneuploidy
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001778 macular degeneration and coagulation disorders|coagulation disorder|dysregulated complement or coagulation systems impact disease|macular degeneration or coagulation disorders|coagulopathies|C19+ Coagulation|coagulation disorders|blood coagulation|CD disorders and disorders of coagulation|coagulation dysfunction
MESH:D002318 cardiovascular disease
MESH:D003324 coronary artery disease
MESH:D003371 Cough|cough|C19+ Cough
MESH:D003424 CD disorders
MESH:D003643 mortality|Mortality|deaths|died|Death HR|death
MESH:D003920 diabetes
MESH:D003924 Type 2 Diabetes
MESH:D003928 diabetic kidney disease
MESH:D006009 AMD
MESH:D006470 bleeding|hemorrhage
MESH:D006948 hyperactive complement
MESH:D006973 Hypertension|hypertension
MESH:D007153 complement deficiencies|complement deficiency disorders|complement deficiency disorder|complement disorders
MESH:D007239 infections|infection
MESH:D007249 inflammation
MESH:D008268 macular degeneration (macula), complement deficiency disorders|macular degeneration, coagulatory disorders
MESH:D009765 obesity|Obesity
MESH:D012131 respiratory failure
MESH:D012162 degeneration
MESH:D012640 fits|binomial fits
MESH:D013921 thrombocytopenia
MESH:D013927 thrombosis
MESH:D015658 human disease
MESH:D016638 Critically
MESH:D018352 CoV infections
MESH:D020246 venous thrombosis
MESH:D054556 venous thromboembolism
MESH:D056587 Complement dysregulation
MESH:D058745 error band
OMIM:612348 complement activation disorders
rs10849829
G/A,T
OASL 8638 12:121032453 1
 33205496
Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment.
Al-Eitan LN, et. al. (2020); Rev Med Virol; 2020 Nov 17 2194. doi:10.1002/rmv.2194
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|SARS-CoV infection|Coronavirus disease 2019|novel coronavirus pneumonia|SARS-CoV-2 infections|CoV-2 infection|coronavirus disease-2019|Covid-19|COVID-19|Covid 19 pneumonia
MESH:D000072658 NSTEMI
MESH:D000740 anemia|anaemia
MESH:D000743 Haemolytic anaemia|hemolytic anemia
MESH:D001102 viral diseases|viral infection
MESH:D001172 rheumatoid arthritis
MESH:D001327 autoimmune disease|autoimmune diseases
MESH:D001778 coagulopathy|coagulation
MESH:D002318 cardiovascular disease|cardiovascular diseases
MESH:D002544 ischemic stroke
MESH:D003371 coughing
MESH:D003643 mortality|deaths|mortalities|death
MESH:D003920 diabetes|diabetic
MESH:D003924 type-2 diabetes mellitus
MESH:D005334 fever
MESH:D006461 haemolysis
MESH:D006509 hepatitis B virus|hepatitis B HBeAg|hepatitis B|hepatitis B virus infection
MESH:D006526 thrombocytopenia in hepatitis C|HCV-infected|HCV
MESH:D006973 hypertension|hypertensive
MESH:D007153 immunodeficiency virus
MESH:D007239 infections|infected|infection
MESH:D007249 inflammation
MESH:D008175 lung tumor
MESH:D008179 chronic discoid lupus erythematosus
MESH:D008180 systemic lupus erythematosus
MESH:D008288 malaria|malaria to autoimmunity
MESH:D009203 myocardial infarction
MESH:D009336 tumour necrosis
MESH:D010300 PD
MESH:D011014 pneumonia|lung inflammation
MESH:D012128 acute respiratory distress syndrome
MESH:D012131 lung failure
MESH:D012140 respiratory disease
MESH:D012141 lung infections|respiratory infections
MESH:D012216 rheumatic
MESH:D013921 thrombocytopenia
MESH:D015047 zoonotic
MESH:D015658 HIV-infected|HIV
MESH:D017093 decreased hepatic midazolam metabolism
MESH:D018352 coronavirus infection|Middle East Respiratory Syndrome|middle east respiratory syndrome|Middle East respiratory syndrome
MESH:D019698 chronic hepatitis C
MESH:D024821 metabolic syndrome
MESH:D052439 lipid toxicity
MESH:D054058 acute coronary syndrome|coronary syndrome
MESH:D055370 lung injury
MESH:D058186 acute renal failure
MESH:D063806 muscle pain
MESH:D064420 toxicity
rs1085307856
A/AG
ASXL1 171023 20:32434638 1
 32708264
Clinico-Biological Features and Clonal Hematopoiesis in Patients with Severe COVID-19.
Duployez N, et. al. (2020); Cancers (Basel); 2020 Jul 21 ; 12 (7) . doi:10.3390/cancers12071992
MESH:C000657245 coronavirus disease 2019|SARS-CoV-2 infection|Coronavirus disease 2019|COVID-19
MESH:C536227 hematopoiesis|Clonal hematopoiesis|Clonal Hematopoiesis|Hematopoiesis-Negative Clonal Hematopoiesis-Positive|blood count CH Clonal hematopoiesis CHIP Clonal hematopoiesis|Hematopoiesis
MESH:C538011 obliterative arterial disease
MESH:C564258 myocardial infarction and obliterative arterial disease
MESH:D000079225 stress|Stress-Induced Abnormalities and Clonal Hematopoiesis
MESH:D000783 arterial disease|000 Arterial disease
MESH:D002318 Hematopoiesis and Cardiovascular Disease|cardiovascular diseases
MESH:D002544 ischemic stroke
MESH:D003141 Infectious Diseases|infectious disease
MESH:D003324 coronary heart disease
MESH:D003371 Cough
MESH:D003643 mortality|Death|death
MESH:D003920 diabetes|Diabete
MESH:D004417 Dyspnea
MESH:D005221 Tiredness
MESH:D005334 Fever
MESH:D005355 Cirrhosis
MESH:D006261 Headache
MESH:D006333 Ischemic Heart Failure|Cardiac failure
MESH:D006402 cytopenias
MESH:D006973 hypertension
MESH:D007022 Clonal Hematopoiesis and Blood-Cancer
MESH:D007239 infection|infected
MESH:D007249 inflammation
MESH:D009190 myelodysplastic syndromes
MESH:D009196 myeloproliferative neoplasms
MESH:D009203 Myocardial infarction|myocardial infarction
MESH:D009369 malignancy|cancer|cancers|tumor|myeloid malignancies|hematological cancer
MESH:D009765 obesity
MESH:D011655 pulmonary embolism|Pulmonary Embolism
MESH:D012140 Respiratory illness|respiratory diseases
MESH:D012817 Gastrointestinal symptoms
MESH:D015470 acute myeloid leukemia
MESH:D019337 myeloid hematological malignancies|hematological malignancies|Hematological malignancy|hematological malignancy
MESH:D020246 deep vein thrombosis
MESH:D020521 Stroke|strokes
MESH:D029424 chronic obstructive pulmonary disease
MESH:D050197 Atherosclerotic Cardiovascular Disease
MESH:D051437 000 Renal insufficiency
MESH:D054437 myelodysplastic/myeloproliferative neoplasms
MESH:D054556 venous thromboembolic disease|Venous thromboembolic disease
MESH:D063806 Muscle pain
rs10853727
T/C
IFNL4 101180976 19:39249823 1
 26038748
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.
Egli A, et. al. (2014); Emerg Microbes Infect; 2014 Jul; 3(7) 51. doi:10.1038/emi.2014.51
MESH:C000657245 SARS-CoV
MESH:C536528 van der Waals
MESH:C564133 atopy
MESH:D001102 Viral infections|viral infection|viral tropism|Viral infection|viral infections
MESH:D001249 asthma
MESH:D001327 autoimmune disease|autoimmune diseases
MESH:D001424 bacterial infections
MESH:D003141 Infectious diseases|infectious diseases
MESH:D003586 cytomegalovirus infection
MESH:D004342 allergic airway disease
MESH:D005767 gastrointestinal
MESH:D006509 hepatitis B
MESH:D006526 hepatitis C viral|hepatitis C|hepatitis C virus infections|HCV-infected|chronic HCV infection|Sendai virusand hepatitis C virus|hepatitis C virus-infected|impaired clearance of hepatitis C|HCV infection|hepatitis C virus 1B infection|HIV/HCV co-infected|hepatitis C virus infection
MESH:D006528 hepatoma
MESH:D007239 CMV-infected|infection
MESH:D007249 inflammation
MESH:D007251 influenza A virus infection
MESH:D007674 embryonic kidney
MESH:D008171 infection of lung|lung diseases
MESH:D008180 systemic lupus erythematosus
MESH:D009103 multiple sclerosis
MESH:D011565 psoriasis
MESH:D014766 CMV viremia
MESH:D015179 CMV infection increases colonic
MESH:D015458 T-cell leukemia virus type-1 mono-infection
MESH:D015658 HIV/HCV-coinfected|Hantaan virus infection|HIV|Virus infection|HIV-1 coinfected|immunodeficiency virus type 1 infection
MESH:D018352 respiratory syndrome coronavirus
MESH:D019698 chronic hepatitis C virus infection|chronic hepatitis C|chronic hepatitis C viral infection|chronic hepatitis C virus type 1 infection|acute hepatitis C
MESH:D020336 spastic paraparesis
MESH:D056486 posttransplant hepatitis c infection|liver damage|hepatitis
MESH:D059787 acute virus infection
MESH:D060085 HCV-coinfected
rs10877012
G/C,T
CYP27B1 1594 12:57768302 1
 33537824
Potential immunomodulatory effects of vitamin D in the prevention of severe coronavirus disease 2019: An ally for Latin America (Review).
Turrubiates-Hernández FJ, et. al. (2021); Int J Mol Med; 2021 04 ; 47 (4) . doi:10.3892/ijmm.2021.4865
MESH:C000657245 covid-19|COVID-19 pneumonia|coronavirus disease 2019|SARS-CoV-2 infection|novel coronavirus pneumonia|2019 infection|COVID Quasi|CoV-2 infection|2019-nCoV infection|cOVID-19|COVID-19|COVID|new coronavirus disease
MESH:C565301 25(OH)D deficiency|25(OH)DNephrotic syndrome
MESH:D000071069 dry conditions
MESH:D000309 insufficiency/deficiency|insufficiency
MESH:D001171 still deficiencies
MESH:D001172 rheumatoid arthritis
MESH:D001327 autoimmune diseases
MESH:D001991 bronchitis
MESH:D002277 guias alimentarias para
MESH:D002318 cardiovascular disease
MESH:D002908 chronic diseases
MESH:D003398 CRS
MESH:D003550 cystic fibrosis
MESH:D003643 mortality|Mortality|deaths|death|mortal
MESH:D003920 diabetes
MESH:D004403 diarrheal disease
MESH:D004421 Excess 1,25(OH)2D
MESH:D004681 autoimmune encephalomyelitis
MESH:D004827 epilepsy
MESH:D005862 Brasileira de Endocrinologia e Metabologia|Deficiencia de vitamina
MESH:D006333 25(OH)DLiver failure
MESH:D006934 hypercalcemia
MESH:D006973 hypertension
MESH:D007239 infections|infection|infected
MESH:D007249 inflammation
MESH:D007674 glomerular diseases|Kidney Disease|kidney disease
MESH:D008180 systemic lupus erythe-matosus-the hype|systemic lupus erythematosus
MESH:D008286 malabsorption syndromes|intestinal malabsorption syndromes
MESH:D009102 multiple organ failure|multiple organ damage
MESH:D009369 cancer
MESH:D009404 nephrotic syndrome
MESH:D009765 obesity
MESH:D010018 osteomalacia
MESH:D010859 skin pigmentation|skin cancerSkin pigmentation
MESH:D011014 pneumonia
MESH:D011507 proteinuria Decreased synthesis of 1,25(OH)2DChronic kidney disease
MESH:D012120 respiratory syndrome
MESH:D012128 Acute respiratory distress syndrome|acute respiratory distress syndrome|ARDS|acute lung injury and the acute respiratory distress syndrome
MESH:D012131 respiratory failure
MESH:D012140 respiratory illnesses
MESH:D012141 acute respiratory tract infection|respiratory infection|acute respiratory tract infections|upper respiratory infection|respiratory tract infections|respiratory infections
MESH:D012778 short bowel syndrome
MESH:D012818 respiratory symptoms
MESH:D013471 sunburn
MESH:D014397 pulmonary tuberculosis
MESH:D015212 inflammatory bowel disease
MESH:D016638 critically ill
MESH:D017093 liver failure
MESH:D018352 respiratory syndrome coronavirus infection|coronavirus disease|MERS|Middle East respiratory syndrome
MESH:D051437 Decreased renal mass
MESH:D054740 tolerogenic dendritic cell
MESH:D055370 lung injury
MESH:D055371 acute lung injury
MESH:D058625 deficiency in chronic liver disease|Chronic liver disease Decreased hydroxylation
rs10896434 Affx-5781220
C/A
LOC107984344 107984344 11:69122694 1
 33359911
Naringerin as candidate drug against SARS-CoV-2: The role for TPC2 genomic variants in COVID-19.
Di Maria E, et. al. (2020); Pharmacol Res; 2020 Dec 24 105402. doi:10.1016/j.phrs.2020.105402
MESH:C000657245 CoV-2 infection|SARS-CoV-2 infection|Covid-19|COVID-19
MESH:D002318 cardiovascular disease
MESH:D003920 diabetes
MESH:D006526 hepatitis C virus (HCV) infection|hepatitis C virus secretion
MESH:D007239 infected
MESH:D008659 metabolic disorders
MESH:D012131 respiratory failure
MESH:D018352 MERS|CoVs infection
rs10900585
G/T
ATP2B4 493 1:203684896 1
 33277640
Host genetics and infectious disease: new tools, insights and translational opportunities.
Kwok AJ, et. al. (2021); Nat Rev Genet; 2021 03 ; 22 (3) 137-153. doi:10.1038/s41576-020-00297-6
MESH:C000657245 covid-19|SARS-CoV-2 infection|Covid-19|COVID-19|COVID
MESH:C535338 total meningitis
MESH:C536020 agammaglobulinaemia|X-linked agammaglobulinaemia
MESH:C537005 C5-C9 deficiency C5, C6, C7
MESH:C537409 X-linked agammaglobulinemia
MESH:C537979 candidiasis CARD9
MESH:C563662 Invasive pneumococcal|invasive pneumococcal disease
MESH:C565169 pus Complement deficiencies C3 deficiency C3 AR Recurrent pyogenic infections
MESH:C565533 CYBA
MESH:C567115 primary immunodeficiency disorders Combined humoral
MESH:D000073296 non-infectious disease
MESH:D000081207 Primary immunodeficiencies|primary immunodeficiency disorders
MESH:D000163 AIDS
MESH:D000267 adhesion deficiency
MESH:D000544 AD
MESH:D000857 anosmia
MESH:D001102 virus disease|virus infection|viral infections
MESH:D001168 progressive polyarthritis|arthritis
MESH:D001170 infectious arthritis
MESH:D001228 Aspergillus infections
MESH:D001260 Ataxia telangiectasia|Ataxia-telangiectasia
MESH:D001327 autoimmunity|autoimmune diseases
MESH:D001424 Pyogenic bacterial infections|bacterial infections
MESH:D002177 candidiasis
MESH:D002180 X-linked Oral candidiasis
MESH:D002494 central nervous system infections
MESH:D003092 colitis
MESH:D003139 common cold
MESH:D003141 infectious disease|Infectious diseases|infectious diseases|multiple diseases|Infectious disease|infectious disease GWAS
MESH:D003371 cough
MESH:D003457 cryptosporidiosis Phagocytic cell defects Chronic granulomatous disease
MESH:D003643 mortality|death
MESH:D003715 dengue fever
MESH:D003881 Invasive dermatophytic
MESH:D003967 diarrhoea
MESH:D004342 allergy|hypersensitivity
MESH:D004660 encephalitis TLR3 AD Encephalitis|encephalitis
MESH:D004819 Epidermodysplasia verruciformis TMC6
MESH:D005334 fever
MESH:D005955 thalassaemia and glucose 6-phosphate dehydrogenase (G6PD) deficiency
MESH:D006105 chronic granulomatous disease|Chronic granulomatous disease|Granulomatous lesions
MESH:D006509 hepatitis B vaccination|HBV infection|hepatitis B|hepatitis B virus infection
MESH:D006525 viral hepatitis|Viral hepatitis
MESH:D006526 HCV infection|acute hepatitis C virus (HCV) infections|hepatitis C virus infection|hepatitis C virus
MESH:D007022 falciparum parasite to hijack red blood cell cytoskeletal remodelling
MESH:D007105 complex disease
MESH:D007153 Complement deficiencies|immunodeficiency disorders|TLR3 deficiencies|deficiency|complement deficiencies|immunodeficiencies|TLR3 deficiency|immunodeficiency
MESH:D007154 immunological abnormalities
MESH:D007239 skin infections|falciparum-infected|Infections|infection|rhinovirus infections|infections|infected|benign infection
MESH:D007249 inflammation
MESH:D007418 paralytic
MESH:D007710 Klebsiella
MESH:D007918 leprosy lesions|leprosy
MESH:D008232 X-lymphoproliferative disease
MESH:D008288 malaria|Malaria|hepatitis and malaria
MESH:D008586 pneumococcal meningitis
MESH:D008589 meningococcal disease|meningococcal infection|Meningococcal disease|meningococcal
MESH:D008661 inborn error|Inborn errors of type I|inborn errors|Inborn errors
MESH:D009181 fungal infections
MESH:D009336 tumour necrosis
MESH:D009361 invasive disease
MESH:D009369 cancer
MESH:D009765 obesity
MESH:D010272 parasitic infection
MESH:D010518 periodontitis
MESH:D011014 pneumonia|pneumonitis
MESH:D011020 Pneumocystis jirovecii pneumonia
MESH:D011051 paralytic poliomyelitis
MESH:D012131 respiratory failure
MESH:D012140 respiratory disease
MESH:D012141 upper respiratory tract infections
MESH:D012214 Rheumatic heart disease|rheumatic heart disease
MESH:D012409 Rubella vaccination|rubella
MESH:D012480 nontyphoidal Salmonella bacteraemia|Salmonella bacteraemia
MESH:D012640 fitness
MESH:D012878 non-melanoma skin cancer
MESH:D013734 AR Cutaneous and mucosal lesions
MESH:D013746 tetanus
MESH:D014005 Deep dermatophytosis and inherited CARD9 deficiency
MESH:D014376 tuberculosis|Tuberculosis|tuberculosis hyper
MESH:D014390 meningeal tuberculosis
MESH:D014397 pulmonary tuberculosis
MESH:D014435 Non-typhoidalSalmonellainfection Non-typhoidal Salmonella bacteraemia|Typhoid Enteric fever
MESH:D014901 Nile neuroinvasive disease
MESH:D015212 inflammatory bowel disease|inflammatory bowel diseases
MESH:D015658 immunodeficiency virus (HIV) infection|Refs HIV infection|HIV infection|HIV-1 infection|HIV disease
MESH:D016393 hypogammaglobulinaemia or B cell lymphoma
MESH:D016470 bacteremia
MESH:D016511 Combined immunodeficiency|combined immunodeficiency|deficiencies Severe combined immunodeficiency
MESH:D016638 critical illness|critical disease
MESH:D016778 falciparum malaria
MESH:D016870 disseminated Neisseria infections
MESH:D018805 sepsis and pneumonia|sepsis
MESH:D018980 Williams
MESH:D019142 Ebola virus disease
MESH:D019595 Dengue fever Dengue shock syndrome|dengue hemorrhagic fever|dengue shock syndrome
MESH:D019694 Hepatitis B Chronic HBV infection
MESH:D019698 Hepatitis C Chronic HCV infection|chronic hepatitis C
MESH:D020031 Epstein-Barr virus infection
MESH:D020803 simplex virus encephalitis
MESH:D030342 inherited IRF9 deficiency|inherited MDA5 deficiency|genetic disorders|genetic defect|pneumococcal genetic variation|inherited TLR3 deficiency
MESH:D040181 X-linked Invasive disease
MESH:D045169 pneumonitis IRF7 X-linked Severe lung infection
MESH:D053306 hyper-IgM syndrome|hyper IgM syndromes|bronchiectasis Hyper-IgM syndrome AID
MESH:D053358 X-linked anhidrotic ectodermal dysplasia
MESH:D053360 hypohydrotic ectodermal dysplasia
MESH:D053632 IRAK-4 deficiency|bronchiectasis X-linked agammaglobulinaemia BTK X-linked|X-linked Haemophagocytosis
MESH:D056486 Hepatitis
MESH:D058495 haploinsufficiency|Haploinsufficient
rs10902122
C/T
IFITM3 10410 11:321239 1
 33101356
Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene Variants.
Iyer GR, et. al. (2020); Front Genet; 2020 ; 11 861. doi:10.3389/fgene.2020.00861
MESH:C000657245 covid-19|SARS-CoV-2 infection|COVID19|novel coronavirus disease|COVID-19
MESH:C536174 panbronchiolitis
MESH:D001102 viral infection|virus infection|viral infections
MESH:D001249 asthma
MESH:D001988 bronchiolitis
MESH:D002318 cardiovascular disorders
MESH:D003092 colitis
MESH:D003141 infectious diseases
MESH:D003229 conjunctival infection
MESH:D003586 cytomegalovirus disease
MESH:D003643 mortality
MESH:D003715 dengue fever
MESH:D003920 diabetes|diabetes mellitus
MESH:D004342 allergic
MESH:D004417 shortness of breath
MESH:D004675 tick-borne encephalitis
MESH:D005355 fibrosis
MESH:D006333 chronic heart failure
MESH:D006965 hyperplasia
MESH:D007239 establishing infections|infections|infection|infected
MESH:D007249 inflammation
MESH:D008171 lung abnormalities|lung disease|lung diseases
MESH:D009080 Kawasaki disease
MESH:D011009 pneumoconiosis
MESH:D011471 prostate cancer
MESH:D011658 pulmonary fibrosis
MESH:D012128 respiratory distress
MESH:D012131 respiratory disorders|respiratory failure
MESH:D012140 respiratory illness
MESH:D012141 upper respiratory infection
MESH:D014376 tuberculosis
MESH:D014397 pulmonary tuberculosis
MESH:D015179 colorectal cancer
MESH:D015658 HIV-1 infection
MESH:D018352 coronavirus disease|MERS|Middle East Respiratory Syndrome
MESH:D018980 Williams
MESH:D020521 stroke
MESH:D030342 genetic disease
MESH:D054243 vesicular stomatitis virus infection
MESH:D054990 idiopathic pulmonary fibrosis|Idiopathic pulmonary fibrosis
MESH:D055371 acute lung injury
MESH:D055744 invasive pulmonary aspergillosis infection|invasive pulmonary Aspergillosis infection
MESH:D058625 end-stage lung disease
MESH:D064420 memory Cytotoxic T
rs10903032
G/A
LOC107985738 107985738 1:24154374 1
 26038748
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.
Egli A, et. al. (2014); Emerg Microbes Infect; 2014 Jul; 3(7) 51. doi:10.1038/emi.2014.51
MESH:C000657245 SARS-CoV
MESH:C536528 van der Waals
MESH:C564133 atopy
MESH:D001102 Viral infections|viral infection|viral tropism|Viral infection|viral infections
MESH:D001249 asthma
MESH:D001327 autoimmune disease|autoimmune diseases
MESH:D001424 bacterial infections
MESH:D003141 Infectious diseases|infectious diseases
MESH:D003586 cytomegalovirus infection
MESH:D004342 allergic airway disease
MESH:D005767 gastrointestinal
MESH:D006509 hepatitis B
MESH:D006526 hepatitis C viral|hepatitis C|hepatitis C virus infections|HCV-infected|chronic HCV infection|Sendai virusand hepatitis C virus|hepatitis C virus-infected|impaired clearance of hepatitis C|HCV infection|hepatitis C virus 1B infection|HIV/HCV co-infected|hepatitis C virus infection
MESH:D006528 hepatoma
MESH:D007239 CMV-infected|infection
MESH:D007249 inflammation
MESH:D007251 influenza A virus infection
MESH:D007674 embryonic kidney
MESH:D008171 infection of lung|lung diseases
MESH:D008180 systemic lupus erythematosus
MESH:D009103 multiple sclerosis
MESH:D011565 psoriasis
MESH:D014766 CMV viremia
MESH:D015179 CMV infection increases colonic
MESH:D015458 T-cell leukemia virus type-1 mono-infection
MESH:D015658 HIV/HCV-coinfected|Hantaan virus infection|HIV|Virus infection|HIV-1 coinfected|immunodeficiency virus type 1 infection
MESH:D018352 respiratory syndrome coronavirus
MESH:D019698 chronic hepatitis C virus infection|chronic hepatitis C|chronic hepatitis C viral infection|chronic hepatitis C virus type 1 infection|acute hepatitis C
MESH:D020336 spastic paraparesis
MESH:D056486 posttransplant hepatitis c infection|liver damage|hepatitis
MESH:D059787 acute virus infection
MESH:D060085 HCV-coinfected
rs10903034
C/T
LOC107985738 107985738 1:24154415 1
 26038748
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.
Egli A, et. al. (2014); Emerg Microbes Infect; 2014 Jul; 3(7) 51. doi:10.1038/emi.2014.51
MESH:C000657245 SARS-CoV
MESH:C536528 van der Waals
MESH:C564133 atopy
MESH:D001102 Viral infections|viral infection|viral tropism|Viral infection|viral infections
MESH:D001249 asthma
MESH:D001327 autoimmune disease|autoimmune diseases
MESH:D001424 bacterial infections
MESH:D003141 Infectious diseases|infectious diseases
MESH:D003586 cytomegalovirus infection
MESH:D004342 allergic airway disease
MESH:D005767 gastrointestinal
MESH:D006509 hepatitis B
MESH:D006526 hepatitis C viral|hepatitis C|hepatitis C virus infections|HCV-infected|chronic HCV infection|Sendai virusand hepatitis C virus|hepatitis C virus-infected|impaired clearance of hepatitis C|HCV infection|hepatitis C virus 1B infection|HIV/HCV co-infected|hepatitis C virus infection
MESH:D006528 hepatoma
MESH:D007239 CMV-infected|infection
MESH:D007249 inflammation
MESH:D007251 influenza A virus infection
MESH:D007674 embryonic kidney
MESH:D008171 infection of lung|lung diseases
MESH:D008180 systemic lupus erythematosus
MESH:D009103 multiple sclerosis
MESH:D011565 psoriasis
MESH:D014766 CMV viremia
MESH:D015179 CMV infection increases colonic
MESH:D015458 T-cell leukemia virus type-1 mono-infection
MESH:D015658 HIV/HCV-coinfected|Hantaan virus infection|HIV|Virus infection|HIV-1 coinfected|immunodeficiency virus type 1 infection
MESH:D018352 respiratory syndrome coronavirus
MESH:D019698 chronic hepatitis C virus infection|chronic hepatitis C|chronic hepatitis C viral infection|chronic hepatitis C virus type 1 infection|acute hepatitis C
MESH:D020336 spastic paraparesis
MESH:D056486 posttransplant hepatitis c infection|liver damage|hepatitis
MESH:D059787 acute virus infection
MESH:D060085 HCV-coinfected
rs10903035
G/A
LOC107985738 107985738 1:24155450 2
 26038748
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.
Egli A, et. al. (2014); Emerg Microbes Infect; 2014 Jul; 3(7) 51. doi:10.1038/emi.2014.51
MESH:C000657245 SARS-CoV
MESH:C536528 van der Waals
MESH:C564133 atopy
MESH:D001102 Viral infections|viral infection|viral tropism|Viral infection|viral infections
MESH:D001249 asthma
MESH:D001327 autoimmune disease|autoimmune diseases
MESH:D001424 bacterial infections
MESH:D003141 Infectious diseases|infectious diseases
MESH:D003586 cytomegalovirus infection
MESH:D004342 allergic airway disease
MESH:D005767 gastrointestinal
MESH:D006509 hepatitis B
MESH:D006526 hepatitis C viral|hepatitis C|hepatitis C virus infections|HCV-infected|chronic HCV infection|Sendai virusand hepatitis C virus|hepatitis C virus-infected|impaired clearance of hepatitis C|HCV infection|hepatitis C virus 1B infection|HIV/HCV co-infected|hepatitis C virus infection
MESH:D006528 hepatoma
MESH:D007239 CMV-infected|infection
MESH:D007249 inflammation
MESH:D007251 influenza A virus infection
MESH:D007674 embryonic kidney
MESH:D008171 infection of lung|lung diseases
MESH:D008180 systemic lupus erythematosus
MESH:D009103 multiple sclerosis
MESH:D011565 psoriasis
MESH:D014766 CMV viremia
MESH:D015179 CMV infection increases colonic
MESH:D015458 T-cell leukemia virus type-1 mono-infection
MESH:D015658 HIV/HCV-coinfected|Hantaan virus infection|HIV|Virus infection|HIV-1 coinfected|immunodeficiency virus type 1 infection
MESH:D018352 respiratory syndrome coronavirus
MESH:D019698 chronic hepatitis C virus infection|chronic hepatitis C|chronic hepatitis C viral infection|chronic hepatitis C virus type 1 infection|acute hepatitis C
MESH:D020336 spastic paraparesis
MESH:D056486 posttransplant hepatitis c infection|liver damage|hepatitis
MESH:D059787 acute virus infection
MESH:D060085 HCV-coinfected
 28255563
The Role of Type III Interferons in Hepatitis C Virus Infection and Therapy.
Bruening J, et. al. (2017); J Immunol Res; 2017; 20177232361. doi:10.1155/2017/7232361
MESH:C000657245 SARS-CoV
MESH:D000309 insufficient
MESH:D001102 Viral infections|viral infection|Viral infection|viral infections
MESH:D001424 bacterial infections
MESH:D001651 extrahepatic diseases
MESH:D002780 intrahepatic infection
MESH:D004342 allergy
MESH:D005355 fibrosis|cirrhosis
MESH:D006509 hepatitis B
MESH:D006525 viral hepatitis
MESH:D006526 infected chimpanzees HCV infection|Hepatitis C Virus Infection|Hepatitis C Virus|impaired clearance of hepatitis C|HCV infection|hepatitis C|hepatitis C virus infections|chronic HCV infection|Hepatitis C|hepatitis C disease|contracting hepatitis C|hepatitis C virus-infected|Modeling hepatitis C virus infection|acute HCV infection|acute hepatitis C virus infection|hepatitis C virus infection
MESH:D006528 hepatocellular carcinoma|hepatoma|Hepatoma
MESH:D007239 infections|infection
MESH:D007249 inflammation|liver inflammation
MESH:D007251 influenza A virus infection
MESH:D007635 myeloid dendritic
MESH:D008545 melanoma
MESH:D009404 NS
MESH:D014766 viremia
MESH:D015658 HIV/HCV-coinfected|hepatotropic virus infection|Hantaan virus infection|virus infections|Virus infection|virus infection|immunodeficiency virus type 1 infection
MESH:D016751 hepatiti